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TAIWAN TAIWAN TAIWAN TAIWAN ADVENTISTADVENTISTADVENTISTADVENTIST HOSPITALHOSPITALHOSPITALHOSPITAL
VOL.VOL.VOL.VOL.7777,,,, NO.NO.NO.NO.01010101 92929292 01010101 15151515
1. Metronidazole
500 mg
Anegyn® Metronidazole
(91.10.11)
2. Chlorpheniramine
Tab
OBCOOBCOOBCOOBCO /
( 8 mm)
4. Sulpiride 200 mg Surin® Tab Dogmatyl® Tab ODOG2ODOG2ODOG2ODOG2 / (
9.1mm) f 471
1. Alendronate Na. Fosamax® 10mg Fosamax® 70mg OFOS7
/ / /
1 Taxotere®
advanced breast cancer &
colitis, ulcerative
pharmaceutic-
al/
;
30mg
Takeda/
1 Quinidine
Sulfate® Tab
bronchospasm
Xanthium
Phyllocontin
2 Hypoca® Cap OHYP Barnidipine HCl 15mg Ca channel blocker /
Plendil
Norvasc
6 Musco®
LMUS Ambroxol HCl 3mg / ml Expectorant / Mucosolvan®
30 mg Tab
.
(6)
Tosylate
375mg
Wellcome
60IU
Quinaglute® TabLeucomycin ® CapInsulin Autrapid & Insulin ProtaphaneLosec® IV
Melleril® 25mg TabCanestan® CreamSerevent® InhalerSlow-K® TabHeadgen® Tab
DC
Bonefos® InjFOY® InjPicibanil® 5KE Inj.Somatosan® Inj.Sandosdatin® LAR Inj.
Targocid® InjAkineton® Tab
Rinderon®-A OintTopsym® LotionTrusopt® Oph SolnUrea® CreamAluminum® Tab
Dilatrend® TabKBT® TabKlean-Prep® PowderLivial® TabRenitec® 5mg TabSinemet®
CR TabMixtard® Insulin
Aldomet® TabAtropin (Tromine®) TabDiflucan® CapStelazine® TabVit B1 Tab
*PublicPublicPublicPublic 'Tahbdc'(Z:)'Tahbdc'(Z:)'Tahbdc'(Z:)'Tahbdc'(Z:)"2002"2002"2002"2002
1.Dopamine agonist popimrolepramipexolepergolide lisuride
motor fluctuation
0.03% )
2.
( 2 Barkin )
4.
5.
1rule of nines 9% 18% 18% 18% 36%
1%
4
Metalyse® Inj. 10000U.)
Tennecteplase (Metalyse Inj.10000U.)()
( ICU CCU )
Tab. 5mg)
(5) Psychotherapeutic drugsBupropion HCL ( Wellbutrin® S-R Tab.
150mg)
risperidonequetiapineamisulpride )
(2)
clozapine 400 mg/day risperidone 6 mg/day olanzapine 20 mg/day quetiapine quetiapine quetiapine quetiapine
300 mg/day300 mg/day300 mg/day300 mg/dayamisulpride 800mg/day
5
clozapine 300-600mg/mL
IBS 1. 2. 3. 4. 5. 6. 7. 8. 9. Rome II
IBS
IBS
IBS
1. IBS 246 2. 135 IBS
1. IBS 135 2. 246 IBS 1.
2.
4.
IBS Mast cell
6
/
/
IBS
() 5-HT3 5-HT3
serotonin
5-HT3 5-HT3 5-HT4 5-HT3
5-HT3 5-HT3
IBS Ondansetron
Ondansetron (Zofran®)
50 IBS 28 IBS
Ondansetron 5-HT4
5-HT4 acetylcholine prokinesia
7
IBS serotonergic serotonin
enterochromaffin-likeSerotonin 5-HT15-HT25-HT35-HT4 5-HT7
serotonin (acetylcholine tachykinin) 5-HT15-HT3 5-HT4
serotonin 5-HT2a5-HT4 5-HT7Serotonin 5-HT3 5-HT4 5-HT1b/d
5-HT 5-HT1D
5-HT 5-HT3 Alosetron GR-68755 Azasetron Y-25130
CilansetronKC-9946DolasetronMDL-73147 5-HT4 PrucaloprideR0-93877TegaserodHTF-919
Mosapride 5-HT4 PiboserodSB-207266A 5-HT7 5-HT1A Buspiron 5-HT1B/D Sumatriptan 5-HT3 Alosetron (Lotronex® 1 mg/Tab, GlaxoWellcome) FDA Alosetron IBS Alosetron
5-HT3
5-HT3 IBS AlosetronAlosetron IBS
serotonin
462 IBS 335 12 0.1mg 0.5 mg2 mg Alosetron 2 mg Alosetron
623 IBS 1 mg Alosetron
Mebeverine 135 mg 3 12 IBS
647 IBS 324 1 mg Alosetron 323 12
Alosetron 24% 16% Alosetron
AlosetronAlosetron
Dolasetron Mesylate (Anzemet® 50 & 100 mg Tab, Aventis)
8
5-HT4
QT
5-HT4 5-HT4 TagaserodMosaprideML-10302
Tagaserod Prucalopride Cisapride
Mosapride 5-HT3
Tegaserod 24 IBS
Tegaserod 2mg
Tegaserod IBS
Prucalopride IBS
24 Prucalopride 1mg 2mg
Prucalopride 1mg 2mg
Prucalopride
Prucalopride
4824 48 251 Prucalopride 0.5mg 2mg
12
5-HT4 5-HT4 5-HT4
5-HT4 5-HT4
Piboserod 5-HT4
1mg Piboserod 90 % Cisapride IBS Piboserod
Piboserod 20mg 10 IBS
Piboserod
5-HT3)
Sumatriptan 5-HT1a Buspiron (Relac®) fundic tone
5-HT1b/d Sumatriptan
5-HT1b/d Sumatriptan 5-HT1a
5-HT1a 8-OH-DPAT 5-HT1a
5-HT7 5-HT7 IBS
IBS IBS
Rome II
70 %
end-pointfunctional parameter
serotonin 5-HT3 5-HT4
serotonin
10
5-HT3 Alosetron IBS 1. 2. 5-HT3 3. compliance Alosetron IBS
5-HT4 TegaserodPrucalopride QT
Piboserod 5-HT4 IBS 5-HT7 5-HT1b/d Sumatriptan 5-HT1b/d
IBS serotonin5-HT3
IBS
5-HT4
IBS
tachykinin
1. Fabrizio D.P.& Marcello T. “Irritable Bowel Syndrome: new agents targeting serotonin receptor subtypes” Drugs 2001; 61(3): 317 ~ 332.
2. Drugs Facts and Comparisons. 2001
()
8/27
1818181859595959
8 27
1. 184/102mmHg () 63 /min 18
36.4
3. X /
4.
11
Myoglobulin 69.5 < 70 ng/ml
5.
6.1919191915151515 NTG 1# 3 L / minIVF N/S 80 c.c/hr
Bokey 3#
10.610.610.610.6ng/ml ICU
9. ICU 3 L / minIVF with N/S 40c.c./hr Tridil
25mg with HS 250c.c keep 3c.c./hr 2.5%G/S 500c.c.+ Heparin 25000I.U. run
20c.c./hr APTT 1.5~2.0 check
CPK CK-MB2020202056565656 401401401401mg% 8888.1.1.1.1ng/ml
8 / 27 8 / 28 8 / 29 8 / 30
Bokey 1# qd
2.
4.06:0006:0006:0006:00 check CPK CK-MB 363363363363mg% 7.37.37.37.3ng/ml
APT-P/APT-C 61.3/ 33.8
5. T
7.Teria gel topical use for neck sore , and scanol 1# state ; DC Tridil
inj change to Isordil 1#tid po , Xanax 1/2#tid , DC persantin, heparin , Scanol
and Dorsiflex 1#tid x 2 days.
8.1616161600 00 00 00
8 29
1.
2. 666600000000 Cholesterol179mg%( 120~200mg% )
TG 126mg%( 30~200mg% )H.D.L.37.8 ( 35~77mg%)
3. sennapur 2# h.s.
8 30
DC Sennapur 100mmHg
DC Norvasc
....
(>50)
13
(3)
depression)T ST
(2)
(2)
(3)
6.6.6.6. ST 5 (4)
(5)
(4)
3.>70%
4.
CK-MB()CK-BB() 3~12
CK-MB 24 48~72 2.Cardic troponins(
)Troponin I,T,C Troponin-I
MI 3~12 24~48 5~14
MI CK-MB 3.Myoglobin(
) MI MI1~3 12~24
T S-T 24
Troponin-I Myoglobulin CPK
CK-MB Subendocardium infarction
3L/min
(2)
(isosorbide Dinitrate)
30 4~8
2.5~40mg 3~4 (3)
1~2 5mcg/min
5mcg/min
ICU TridilTridilTridilTridil (Nitroglycerin)25mg
with HS 250c.c keep 3c.c./hr 5mcg/min
8/28 Nitrate
IsordilIsordilIsordilIsordil(isosorbide Dinitrate)10mg 1#tid
B. NorvascNorvascNorvascNorvasc(Amlodipine)5mg8/27 1#qd
thiazide
DC
51% ASA
Thromboxane A2()
Prostacyclin I2()
B. Bokey(Aspirin)100mg 3#
Bokey ICU Bokey 100mg 1#
qd
A. Dipyridamole(PAF)(Collagen)
ASA Wafarin Heparin
Dipyridamole ASA
16
ASA
Heparin ASA DC
6.HeparinHeparinHeparinHeparin
Heparin
70~80 units/kg IV bolus
15~18 units/kg/hr aPPT(actived partial thromboplastin time)
(24~40) 1.5~2 2~5
Heparin Aspirin
Heparin
2.5%G/S 500c.c.+ Heparin 25000I.U. run 20c.c./hr
18units/kg/hr MI
6hr APT-p/APT-c 1.5~2 heparin8/28
ST
MI DC Heparin
7.AcertilAcertilAcertilAcertil(perindopril)
2mg qd
8.:
8/27 MgO MgO MgO MgO 1#tid 8/28
scanolscanolscanolscanol() dorsiflexdorsiflexdorsiflexdorsiflex() 1#tid x 2days
XanaxXanaxXanaxXanax(
Alprazolam) 1/2 tid 8/29
SennapurSennapurSennapurSennapur()2# hs 8/30
1. Textbook of Therapeutics,6th edition / p811~p826 / William & Wilkins company 2. The Washiongton Manual of Medical Therapeutics / p81~p92 /
3. Poket Guide to Diagnostic Tests,2nd
edition /
17
methacrylic acid copolymer 150‚ 000tricetinbutyl acetateethyl acetate
ethanol absolute
(Dermatophytes):(Trichophyton)(Microsporum)
1.()()(
)()
2.()
3.()
7. 3—5
oligophrenia phenylalanine
(tyrosine)
aspartame (aspartic acid)
aspartame
TAIWAN TAIWAN TAIWAN TAIWAN ADVENTISTADVENTISTADVENTISTADVENTIST HOSPITALHOSPITALHOSPITALHOSPITAL
VOL.VOL.VOL.VOL.7777,,,, NO.NO.NO.NO.01010101 92929292 01010101 15151515
1. Metronidazole
500 mg
Anegyn® Metronidazole
(91.10.11)
2. Chlorpheniramine
Tab
OBCOOBCOOBCOOBCO /
( 8 mm)
4. Sulpiride 200 mg Surin® Tab Dogmatyl® Tab ODOG2ODOG2ODOG2ODOG2 / (
9.1mm) f 471
1. Alendronate Na. Fosamax® 10mg Fosamax® 70mg OFOS7
/ / /
1 Taxotere®
advanced breast cancer &
colitis, ulcerative
pharmaceutic-
al/
;
30mg
Takeda/
1 Quinidine
Sulfate® Tab
bronchospasm
Xanthium
Phyllocontin
2 Hypoca® Cap OHYP Barnidipine HCl 15mg Ca channel blocker /
Plendil
Norvasc
6 Musco®
LMUS Ambroxol HCl 3mg / ml Expectorant / Mucosolvan®
30 mg Tab
.
(6)
Tosylate
375mg
Wellcome
60IU
Quinaglute® TabLeucomycin ® CapInsulin Autrapid & Insulin ProtaphaneLosec® IV
Melleril® 25mg TabCanestan® CreamSerevent® InhalerSlow-K® TabHeadgen® Tab
DC
Bonefos® InjFOY® InjPicibanil® 5KE Inj.Somatosan® Inj.Sandosdatin® LAR Inj.
Targocid® InjAkineton® Tab
Rinderon®-A OintTopsym® LotionTrusopt® Oph SolnUrea® CreamAluminum® Tab
Dilatrend® TabKBT® TabKlean-Prep® PowderLivial® TabRenitec® 5mg TabSinemet®
CR TabMixtard® Insulin
Aldomet® TabAtropin (Tromine®) TabDiflucan® CapStelazine® TabVit B1 Tab
*PublicPublicPublicPublic 'Tahbdc'(Z:)'Tahbdc'(Z:)'Tahbdc'(Z:)'Tahbdc'(Z:)"2002"2002"2002"2002
1.Dopamine agonist popimrolepramipexolepergolide lisuride
motor fluctuation
0.03% )
2.
( 2 Barkin )
4.
5.
1rule of nines 9% 18% 18% 18% 36%
1%
4
Metalyse® Inj. 10000U.)
Tennecteplase (Metalyse Inj.10000U.)()
( ICU CCU )
Tab. 5mg)
(5) Psychotherapeutic drugsBupropion HCL ( Wellbutrin® S-R Tab.
150mg)
risperidonequetiapineamisulpride )
(2)
clozapine 400 mg/day risperidone 6 mg/day olanzapine 20 mg/day quetiapine quetiapine quetiapine quetiapine
300 mg/day300 mg/day300 mg/day300 mg/dayamisulpride 800mg/day
5
clozapine 300-600mg/mL
IBS 1. 2. 3. 4. 5. 6. 7. 8. 9. Rome II
IBS
IBS
IBS
1. IBS 246 2. 135 IBS
1. IBS 135 2. 246 IBS 1.
2.
4.
IBS Mast cell
6
/
/
IBS
() 5-HT3 5-HT3
serotonin
5-HT3 5-HT3 5-HT4 5-HT3
5-HT3 5-HT3
IBS Ondansetron
Ondansetron (Zofran®)
50 IBS 28 IBS
Ondansetron 5-HT4
5-HT4 acetylcholine prokinesia
7
IBS serotonergic serotonin
enterochromaffin-likeSerotonin 5-HT15-HT25-HT35-HT4 5-HT7
serotonin (acetylcholine tachykinin) 5-HT15-HT3 5-HT4
serotonin 5-HT2a5-HT4 5-HT7Serotonin 5-HT3 5-HT4 5-HT1b/d
5-HT 5-HT1D
5-HT 5-HT3 Alosetron GR-68755 Azasetron Y-25130
CilansetronKC-9946DolasetronMDL-73147 5-HT4 PrucaloprideR0-93877TegaserodHTF-919
Mosapride 5-HT4 PiboserodSB-207266A 5-HT7 5-HT1A Buspiron 5-HT1B/D Sumatriptan 5-HT3 Alosetron (Lotronex® 1 mg/Tab, GlaxoWellcome) FDA Alosetron IBS Alosetron
5-HT3
5-HT3 IBS AlosetronAlosetron IBS
serotonin
462 IBS 335 12 0.1mg 0.5 mg2 mg Alosetron 2 mg Alosetron
623 IBS 1 mg Alosetron
Mebeverine 135 mg 3 12 IBS
647 IBS 324 1 mg Alosetron 323 12
Alosetron 24% 16% Alosetron
AlosetronAlosetron
Dolasetron Mesylate (Anzemet® 50 & 100 mg Tab, Aventis)
8
5-HT4
QT
5-HT4 5-HT4 TagaserodMosaprideML-10302
Tagaserod Prucalopride Cisapride
Mosapride 5-HT3
Tegaserod 24 IBS
Tegaserod 2mg
Tegaserod IBS
Prucalopride IBS
24 Prucalopride 1mg 2mg
Prucalopride 1mg 2mg
Prucalopride
Prucalopride
4824 48 251 Prucalopride 0.5mg 2mg
12
5-HT4 5-HT4 5-HT4
5-HT4 5-HT4
Piboserod 5-HT4
1mg Piboserod 90 % Cisapride IBS Piboserod
Piboserod 20mg 10 IBS
Piboserod
5-HT3)
Sumatriptan 5-HT1a Buspiron (Relac®) fundic tone
5-HT1b/d Sumatriptan
5-HT1b/d Sumatriptan 5-HT1a
5-HT1a 8-OH-DPAT 5-HT1a
5-HT7 5-HT7 IBS
IBS IBS
Rome II
70 %
end-pointfunctional parameter
serotonin 5-HT3 5-HT4
serotonin
10
5-HT3 Alosetron IBS 1. 2. 5-HT3 3. compliance Alosetron IBS
5-HT4 TegaserodPrucalopride QT
Piboserod 5-HT4 IBS 5-HT7 5-HT1b/d Sumatriptan 5-HT1b/d
IBS serotonin5-HT3
IBS
5-HT4
IBS
tachykinin
1. Fabrizio D.P.& Marcello T. “Irritable Bowel Syndrome: new agents targeting serotonin receptor subtypes” Drugs 2001; 61(3): 317 ~ 332.
2. Drugs Facts and Comparisons. 2001
()
8/27
1818181859595959
8 27
1. 184/102mmHg () 63 /min 18
36.4
3. X /
4.
11
Myoglobulin 69.5 < 70 ng/ml
5.
6.1919191915151515 NTG 1# 3 L / minIVF N/S 80 c.c/hr
Bokey 3#
10.610.610.610.6ng/ml ICU
9. ICU 3 L / minIVF with N/S 40c.c./hr Tridil
25mg with HS 250c.c keep 3c.c./hr 2.5%G/S 500c.c.+ Heparin 25000I.U. run
20c.c./hr APTT 1.5~2.0 check
CPK CK-MB2020202056565656 401401401401mg% 8888.1.1.1.1ng/ml
8 / 27 8 / 28 8 / 29 8 / 30
Bokey 1# qd
2.
4.06:0006:0006:0006:00 check CPK CK-MB 363363363363mg% 7.37.37.37.3ng/ml
APT-P/APT-C 61.3/ 33.8
5. T
7.Teria gel topical use for neck sore , and scanol 1# state ; DC Tridil
inj change to Isordil 1#tid po , Xanax 1/2#tid , DC persantin, heparin , Scanol
and Dorsiflex 1#tid x 2 days.
8.1616161600 00 00 00
8 29
1.
2. 666600000000 Cholesterol179mg%( 120~200mg% )
TG 126mg%( 30~200mg% )H.D.L.37.8 ( 35~77mg%)
3. sennapur 2# h.s.
8 30
DC Sennapur 100mmHg
DC Norvasc
....
(>50)
13
(3)
depression)T ST
(2)
(2)
(3)
6.6.6.6. ST 5 (4)
(5)
(4)
3.>70%
4.
CK-MB()CK-BB() 3~12
CK-MB 24 48~72 2.Cardic troponins(
)Troponin I,T,C Troponin-I
MI 3~12 24~48 5~14
MI CK-MB 3.Myoglobin(
) MI MI1~3 12~24
T S-T 24
Troponin-I Myoglobulin CPK
CK-MB Subendocardium infarction
3L/min
(2)
(isosorbide Dinitrate)
30 4~8
2.5~40mg 3~4 (3)
1~2 5mcg/min
5mcg/min
ICU TridilTridilTridilTridil (Nitroglycerin)25mg
with HS 250c.c keep 3c.c./hr 5mcg/min
8/28 Nitrate
IsordilIsordilIsordilIsordil(isosorbide Dinitrate)10mg 1#tid
B. NorvascNorvascNorvascNorvasc(Amlodipine)5mg8/27 1#qd
thiazide
DC
51% ASA
Thromboxane A2()
Prostacyclin I2()
B. Bokey(Aspirin)100mg 3#
Bokey ICU Bokey 100mg 1#
qd
A. Dipyridamole(PAF)(Collagen)
ASA Wafarin Heparin
Dipyridamole ASA
16
ASA
Heparin ASA DC
6.HeparinHeparinHeparinHeparin
Heparin
70~80 units/kg IV bolus
15~18 units/kg/hr aPPT(actived partial thromboplastin time)
(24~40) 1.5~2 2~5
Heparin Aspirin
Heparin
2.5%G/S 500c.c.+ Heparin 25000I.U. run 20c.c./hr
18units/kg/hr MI
6hr APT-p/APT-c 1.5~2 heparin8/28
ST
MI DC Heparin
7.AcertilAcertilAcertilAcertil(perindopril)
2mg qd
8.:
8/27 MgO MgO MgO MgO 1#tid 8/28
scanolscanolscanolscanol() dorsiflexdorsiflexdorsiflexdorsiflex() 1#tid x 2days
XanaxXanaxXanaxXanax(
Alprazolam) 1/2 tid 8/29
SennapurSennapurSennapurSennapur()2# hs 8/30
1. Textbook of Therapeutics,6th edition / p811~p826 / William & Wilkins company 2. The Washiongton Manual of Medical Therapeutics / p81~p92 /
3. Poket Guide to Diagnostic Tests,2nd
edition /
17
methacrylic acid copolymer 150‚ 000tricetinbutyl acetateethyl acetate
ethanol absolute
(Dermatophytes):(Trichophyton)(Microsporum)
1.()()(
)()
2.()
3.()
7. 3—5
oligophrenia phenylalanine
(tyrosine)
aspartame (aspartic acid)
aspartame
