Drugs effecting the digestive organs

function

Part 1

Among substances that influence on functioning of digestive organs there are

following groups of drugs:Drugs which influence on appetite;

Emetic and antiemetic drugs;

Drugs which are used in case of disturbed function of gastric glands;

Drugs effecting liver function;

Drugs used in case of disturbed excretory function of pancreas;

Laxative agents;

Drugs which influence on motor function of intestines

Drugs which influence on

appetite:

Drugs which improve appetite

Drugs which depress appetite

Гіркоти

Полин гіркий

Золототисячник малий

Деревій звичайний

PhepranonumForm of production - 0,025 g tablets

Mechanism of action of emetic and antiemetic drugs

Metoclopramide, reglan and cerucalFrom of production: 0,01 g tablets, ampoules with 2 ml of 0,5 % solution.

MotiliumForm of production: 0,01 g tablets

Drugs which stimulate gastric secretion:

With diagnostic aim: caffeine, histamine, gastrin.With treating aim: plantain juice, plantaglucide, natural gastric juice, pepsin, hydrochloric acid.

Drugs which depress gastric secretion:

Drugs which block choline receptros:M-cholinoblockers (nonselective cholionolyutics): atropine sulfateM1-cholinoblockers with selective action (selective cholinolytics): gastrozepinganglioblockers: pirilen, benzohexonium

Drugs which block histamine-Н2-receptors: cimetidine, renitidine, famotidine, nizatidine, rexatidineInhibitors of proton pump: omeprazole, controlokProstaglandines and their synthetic derivatives: misoprostolAntacid drugs:

System: sodium hydrocarbonateNonsystem: aluminum hydroxide, magnesium oxide, almagel, maalox, renni

Gastroprotectors:Drugs which form mechanic protection of mucous membrane of stomach: sucralfate, de-nolDrugs which increase protective function of mucous barrier and stability of mucous membrane towards action of damaging factor: carbenoxolon, misoprostol

Atropine sulfate (Atropini sulfas). Powder for preparation of 0,5 % and 1 % eye drops, 1% eye

ointment, 0,0005 g tablets, ampoules with 1 ml of 0,1 % solution.

Gastrozepin (Gastrocepinum) Forms of production: 0,025 g and 0,05 g tablets; ampoules

with 0,01 g of dry substance.

Cimetidine Form of production: 0, 2 g tablets.

Ranitidine (Ranitidin) Forms of production: 0,15 g and 0,3 g tablets and ampoules with 2 ml of

2,5 % solution.

FamotidinForms of production: 0,02 g and 0,04 g tablets.

Omeprazole Form of production – 0,02 g capsules.

Antaciddrugs

Systemantacids

Nonsystemantacids

AlmagelCombined drug which contains gel of aluminum hydroxide,

magnesium oxide and D-sorbit. Form of production: 170 ml bottles.

Antacid drugs

Maalox Combined rugs which contains gel of aluminum hydroxide,

magnesium oxide.

Sucralfate Form of production: 1 g tablets

De-nolForm of production: 0,12g tablets.

Pylobact Omeprazole + Clarythromycin + Tinidazole

Schemes of combined treatment of gastric ulcer

De-nol + amoxycillin

De-nol + metronidazole

Omeprazole + amoxycillin + clarythromycin

De-nol + clarythromycin + metronidazole

De-nol + controlok + amoxycilin + clarythromycin