8/18/2019 Eliminasi Dan Ekskresi Toksikan

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ELIMINASI DAN EKSKRESITOKSIKANDAN FAKTOR YANG MEMPENGARUHI

Hodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey

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• &e'(')*(n *nt*k

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'eningk(tny(ko')leksit(s s*(t*org(nis'eHodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey

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A&T- /A$MEM1E$AH"..• k*r(n T*b*h

• (tio *(s 1er'*k((n T*b*h deng(nM(ss( T*b*h

• &o')(rte'en T*b*h i.e., cells,tiss*es, org(ns5.

•  J*'l(h i)id

• 6(rriers terh(d() ingk*ng(nEkstern(lHodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey

8/18/2019 Eliminasi Dan Ekskresi Toksikan

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-A$ T6H /A$6E1EA$ 75

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d(r(h

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toxic:

;ieli'in(si ke d(l('e')ed*

Hodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey

8/18/2019 Eliminasi Dan Ekskresi Toksikan

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-A$ T6H /A$6E1EA$ 25

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d(n eli'in(si 'et(bolit'el(l*i *rine

H(l y(ng 'e')eng(r*hieli'in(si toksik(n 'el(l*igin

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-A$ T6H /A$6E1EA$ 35

1(d( Al+eoli #• )t(ke -2 ke d(r(h• Eli'in(si =-2 d(ri d(r(h• Eli'in(si toksik(n y(ng

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1roses DIFUSI PASIF

Hodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey

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-A$ T6H /A$ 6E1EA$45

-rg(n T*b*h y(ng ber)er(n d(l(' 

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1roses Tr(ns)ort Toksik(n keEli'in(tion 1oint #

Hodgson, E. A Textbook of Modern Toxicology 3rd ed. 2004. John Wiley !ons,"nc # $e% Jersey