generation of functional human pancreatic β cells in vitro felicia w. pagliuca, jeffrey r. millman,...
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![Page 1: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/1.jpg)
Generation of Functional Human Pancreatic β Cells In Vitro
Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer Hyoje Ryu, Quinn P. Peterson, Dale Greiner, Douglas A. Melton
Cell Volume 159, Issue 2, Pages 428-439 (October 2014)
DOI: 10.1016/j.cell.2014.09.040
Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 2: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/2.jpg)
Figure 1
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 3: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/3.jpg)
Figure 2
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 4: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/4.jpg)
Figure 3
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 5: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/5.jpg)
Figure 4
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 6: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/6.jpg)
Figure 5
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 7: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/7.jpg)
Figure 6
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 8: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/8.jpg)
Figure S1
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 9: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/9.jpg)
Figure S2
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 10: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/10.jpg)
Figure S3
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 11: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/11.jpg)
Figure S4
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 12: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/12.jpg)
Figure S5
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions
![Page 13: Generation of Functional Human Pancreatic β Cells In Vitro Felicia W. Pagliuca, Jeffrey R. Millman, Mads Gürtler, Michael Segel, Alana Van Dervort, Jennifer](https://reader036.vdocuments.pub/reader036/viewer/2022062715/56649d765503460f94a57a28/html5/thumbnails/13.jpg)
Cell 2014 159, 428-439DOI: (10.1016/j.cell.2014.09.040) Copyright © 2014 Elsevier Inc. Terms and Conditions