2005

NitrilesQ 0520 Highly Enantioselective Cyanosilylation of Aldehydes Catalyzed by Novel

β-Amino Alcohol—Titanium Complexes. — Under optimized conditions, aromatic, conjugated, heteroaromatic, and aliphatic aldehydes react with TmsCN in the presence of only 5 mol% of Ti(OiPr)4/(+)-AMA (1:1) to give Tms ethers of cyanohydrins in high yields and up to 94% enantioselectivities. — (LI, Y.; HE, B.; QIN, B.; FENG*, X.; ZHANG, G.; J. Org. Chem. 69 (2004) 23, 7910-7913; Key Lab. Green Chem. Technol., Sichuan Univ., Chengdu, Sichuan 610064, Peop. Rep. China; Eng.) — Klein

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