hla-drb1 ∗ 0401 and hla-drb1 ∗ 0408 are strongly associated with the development of antibodies...

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HLA-DRB1 0401 and HLA-DRB1 0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis Steve Hoffmann, Sabine Cepok, Verena Grummel, Klaus Lehmann-Horn, Jörg Hackermueller, Peter F. Stadler, Hans-Peter Hartung, Achim Berthele, Florian Deisenhammer, Ralf Wasmuth, Bernhard Hemmer The American Journal of Human Genetics Volume 83, Issue 2, Pages 219-227 (August 2008) DOI: 10.1016/j.ajhg.2008.07.006 Copyright © 2008 The American Society of Human Genetics Terms and Conditions

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Page 1: HLA-DRB1 ∗ 0401 and HLA-DRB1 ∗ 0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis Steve

HLA-DRB1 0401 and HLA-DRB1 0408 Are Strongly Associated with the Development ∗ ∗of Antibodies against Interferon-β Therapy in Multiple Sclerosis 

Steve Hoffmann, Sabine Cepok, Verena Grummel, Klaus Lehmann-Horn, Jörg Hackermueller, Peter F. Stadler, Hans-Peter Hartung, Achim Berthele, Florian Deisenhammer, Ralf Wasmuth, Bernhard Hemmer 

The American Journal of Human Genetics Volume 83, Issue 2, Pages 219-227 (August 2008)

DOI: 10.1016/j.ajhg.2008.07.006

Copyright © 2008 The American Society of Human Genetics Terms and Conditions

Page 2: HLA-DRB1 ∗ 0401 and HLA-DRB1 ∗ 0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis Steve

Figure 1

The American Journal of Human Genetics 2008 83, 219-227DOI: (10.1016/j.ajhg.2008.07.006) Copyright © 2008 The American Society of Human Genetics Terms and Conditions

Page 3: HLA-DRB1 ∗ 0401 and HLA-DRB1 ∗ 0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis Steve

Figure 2

The American Journal of Human Genetics 2008 83, 219-227DOI: (10.1016/j.ajhg.2008.07.006) Copyright © 2008 The American Society of Human Genetics Terms and Conditions

Page 4: HLA-DRB1 ∗ 0401 and HLA-DRB1 ∗ 0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis Steve

Figure 3

The American Journal of Human Genetics 2008 83, 219-227DOI: (10.1016/j.ajhg.2008.07.006) Copyright © 2008 The American Society of Human Genetics Terms and Conditions