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Basel has been the scene of events, discoveries and ideas that initially seemed insignificant but later altered the world: the discovery of LSD and DDT, the impact of the Basel Mission, the Zionist World Congress. Personalities like Hans Holbein, Karl Jaspers and Friedrich Nietzsche once lived here, moulding the city and helping to make its name known around the world. Who remembers the once world famous figure-skaters ‹Frick and Frack›? What has Basel got to do with the international cocoa trade, or with the beginnings of nature conservation? And did you know that the very first time the Koran appeared in printed form was in this strictly Protestant city on the river Rhine? The authors Matthias Buschle and Daniel Hagmann have collated numerous exciting and informative stories to produce a treasure trove for anyone interested in history and an Eldorado for anyone who is simply curious. About the authors: Matthias Buschle (*1970) is an art historian, journalist and exhibition curat

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Page 1: How Basel changed the world

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Page 3: How Basel changed the world

How Baselchanged the worldBy Matthias Buschle and Daniel Hagmann

Christoph Merian Verlag

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Table of Contentsp. 9

Introduction

p. 13“ Sugar … spinach …

haemoglobin. ”The measurements of

Gustav von Bunge

p. 20“ This is such stuff

as dreams are made of. ”The discovery

of LSD

p. 28Freidorf

and Bauhaus. Global architecture

on Basel foundations

p. 34Ice-skaters,

Idioms, Slang and Erasmus

of Rotterdam

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p. 39The Art of

Art Dealing. Art Basel

p. 44The Bells of Basel.

The modern woman and

world peace

p. 50Excuse me, but

where is Basel III ?The city and the

Bank for International Settlements

p. 55A “ painting

to dream about ”.Die Toteninsel

p. 60Love of Animals,

Bone Screws, IPOs.

The boom in accident surgery

p. 65Cortisone and

Vitamin C.Tadeus Reichstein,

a master of the tiniest substances

p. 71A Bitter-Sweet Success Story.The missions,

slave liberationand the

cocoa trade

p. 77Habent sua fata libelli.

The Civilizing Process

p. 82A Bad Leg.

Paracelsus and the reform of

modernmedicine

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p. 90Romantic Matriarchy.

Johann Jakob Bachofen

and mother right

p. 96The Stumbling Block.

The origins of global nature

conservation

p. 103Poison for the World.

Dichlorodiphenyl-trichloroethane

becomes DDT

p. 108A Song for

Peace.Mediating between

revolution and monarchy

in Basel

p. 114SPQB

instead of SPQR.

Conclave and papal coronation

in Basel

p. 121Nietzsche’s First Book.

The tragedy at the birth of

his philosophy

p. 129Explosive !

Christian Friedrich Schönbein

and guncotton

p. 134A Clash of Cultures.

The commotion caused by

the fi rst printing of the Koran

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p. 141New Early Music.

The Schola Cantorum Basiliensis

and Paul Sacher

p. 148“ In Basel I founded the Jewish State. ”

The Zionist Congress in Basel

p. 154A Typeface

travels the World.How the

Haas Grotesk became

Helvetica

p. 160The Bernoulli

Century. Eight representatives

of one family infl uence the world.

p. 164Russian Reverse.

Yet another change

p. 173Thanks

p. 175Imprint

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Introduction“ Is it possible for the fl ap of a butterfl y’s wing in Brazil to set off a tornado in Texas ? ” The mathemat-ician, meteorologist and co-inventor of Chaos The-ory, Edward N. Lorenz, raised this issue in 1972. In our little chronicle, How Basel changed the world, we intend to pursue this butterfl y eff ect, albeit from a rather local perspective : the centre of the world in this book is Basel. Here too, world-shaking events have taken place and the eff ects of experiences and discoveries here have ultimately been felt across the globe – irrespective of their apparent irrelevance at the time or their subordinate importance, as well as the role originally played by chance.

The German news magazine Der Spiegel called the city of Basel a “ global city in pocket-book for-

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mat ”. But is Basel really a city of world importance ? Although global players of world renown have been active here, and indeed still are – one only has to think of Erasmus of Rotterdam, Friedrich Nietzsche, Herzog & de Meuron and the Basel “ Chemische ” (chemical industries) – Basel is more a provincial town than a metropolis. What is more, in the ori-ginal sense of the term “ provincial ” it is an inde-pendent part of a larger whole. If small events can unpredictably alter a system in the long-term, then world history can also be changed from Basel. There would be a correspondence between the but-terfl y in Brazil and the black-headed gull in the air above the so-called knee of the river Rhine …

This book tracks down such impacts by viewing the world from Basel and asking : What happened here that had global consequences ? What ideas and products from Basel have infl uenced the course of world history ?

How Basel changed the world is a book about local history, written out of love of country, and very much in the spirit of the great Swiss author Gerhard Meier : “ I believe that you only become a world citizen through being a provincial. You have to go through the offi cial channels : from provincial to global citizen. ” How Basel changed the world may involve a touch of navel gazing, but it does so with-out self-aggrandizement. It is based on a diff erent prototype, namely, the St. Mary Mead Principle. This fi ctional English town is in a position to pre-sent remarkable crime statistics : over a space of

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about forty years, sixteen murders were committed there. In the words of Miss Marple : “ Terrible things happen in a place like this, I tell you. You have the opportunity to observe things here like you never have in a city. ” Agatha Christie’s Miss Marple, a somewhat singular older lady, solves her cases with the help of a simple but extremely eff ective prin-ciple : she questions odd everyday things, fi nding in them the key to the crimes. “ Who cut holes in Mrs Jones’s net shopping bag ? Why did Mrs Sims only wear her new fur coat once ? ” How Basel changed the world does not engage in criminalistics, but like St. Mary Mead, Basel here becomes a backdrop against which to view the world.

But why Basel ? The words of at least one prom-inent witness speak for the choice of the city on the knee of the Rhine : “ Basel seems to me to be either at the heart of Christianity, or else to be situated not very far from it. ” Enea Silvio Piccolomini, later known as Pope Pius II, wrote this on the occasion of the Council of Basel (1431 – 1449). To put it in today’s terms : What is special about Basel is not that this city is more closely linked than any other with world history, but the way in which it is linked. Whereby “ world ” here means not “ the whole world ” but rather “ the surrounding world ”, the concentric-ally expandable region around the city. Sometimes the impacts have extended far out over the world’s oceans, sometimes they have only eff ected Europe.

This book is an “ essay ” in the original sense, an experiment. It actually consists of a number of

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essays, freely formulated texts in a non-scientifi c language. It is a book that keep to the facts, while sometimes pointing up links with a certain relish and humour The choice of stories adheres to the same principle : whereas an attempt has been made to take the most important “ world events ” into account, the intention is not to fl aunt achievement. The small, sometimes almost forgotten story is of equal importance.

How Basel changed the world could of course have many more pages and include, for example, the signifi cance of the 20th century church father, Karl Barth, the fi rst Indian rhinoceros worldwide to be born in a zoo, the impact on everyday life of those little helpers Valium and Ritalin, the history of ready-made pastry, the links between capital, rum and the slave trade, the settlement of the dan-gerous giant hogweed in Europe or the birth of the concept of freedom from pain.

Matthias Buschle and Daniel Hagmann

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“ Sugar … spinach … haemoglobin. ”

The measurements of Gustav von Bunge

“ 100 g dry matter contain mg of iron : Sugar … 0 / Blood serum … 0 / Chicken egg white … trace / Honey … 1.2 / Rice … 1.0 – 2.0 / Pearl barley … 1.4 – 1.5 / Pears … 2.0 / Dates … 2.1 / cow’s milk … 2.3 / mother’s milk … 2.3 – 3.1 / Plums … 2.8 / dog’s milk … 3.2 / fi gs … 3.7 / raspberries … 3.9 / peeled hazelnuts … 4.3 / Barley … 4.5 / Cabbage, inner yel-low leaves … 4.5 / Rye … 4.9 / Peeled almonds … 4.9 / Wheat … 5.5 / Grapes (Malaga) … 5.6 / Blue-berries … 5.7 / Potatoes … 6.4 / Peas … 6.2 – 6.6 / Cherries, black, stone-less … 7.2 / Beans, white … 8.3 / Carrots … 8.6 / Wheat bran … 8.8 / Strawber-ries … 8.6 – 9.3 / Lentils … 9.5 / Almonds, brown skins … 9.5 / Cherries, red, stone-less … 10 / Hazel-nuts, brown skins … 13 / Apples … 13 / Dandelion,

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leaves … 14 / Cabbage, outer green leaves … 17 / Asparagus … 20 / Egg yolk … 10 – 24 / Spinach … 33 – 39 / Pig’s blood … 226 / Hematogen … 290 / Hemoglobin … 340 ”

It was this table compiled by the Basel physi-ologist Gustav von Bunge (1844 – 1920) that consol-idated the victory of spinach as the vegetable with the highest iron content. It was printed in the fi rst edition of his Lehrbuch der Physiologie des Menschen (Textbook of Physiological and Pathological Chemis-try) in 1901. The iron values rise as the list of sub-stances proceeds : sugar has no iron, haemoglobin, the colour component of red blood vessels, has the most (moreover, haematogen is a substance that von Bunge himself fi rst tracked down ; the word “ haematogen ” – coined by him as a transitional term – means blood-producer). Spinach is the last vegetable on the list, so it is the vegetable contain-ing the most iron.

There is a decisive qualifi cation, however, and this is mentioned in the fi rst line of the list : “ con-tained in 100 g dry matter ”. Now we do not eat spin-ach in powder form. The plant consists to a good 90 % of water, meaning that what we eat only con-tains 3.3 to 3.9 mg iron per 100 g – which may make spinach an iron-rich vegetable, but does not achieve the outstanding values of the powder form.

Faulty reasoning : The spinach example is often used in reference texts and newspaper articles when writing about faulty reasoning. After all, this error had far-reaching eff ects : generations of chil-

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dren were fed spinach, although only very few of them like the bitter-tasting vegetable. There are even stories about mothers cooking vanilla pud-ding with spinach in the hope that this sweet cam-oufl age might make eating it more pleasant for their children.

There was a similar trick behind the invention of the comic fi gure Popeye the Sailor Man in the USA in 1929 ; one year later, Popeye even made it into animated cartoons. In critical situations – not in his early years, but only when Popeye was used in nutrition campaigns – the sailor opened a tin of spinach and ate it. Immediately, he turned into a muscle man who overcame his opponents through the power of spinach. In any case, the sure winner in this early PR-campaign was the manufacturer of tinned spinach : consumption of it increased by a third as a result.

A thinker. But back to Basel and Gustav von Bunge. He was born in Dorpat (today Tartu, Es -tonia), where the family belonged to the small Ger-man upper-class. It was in Dorpat that he completed his chemistry studies and wrote his post-doctoral treatise in the fi eld of physiology. He then went on to study medicine in Leipzig and Strasbourg and received a doctorate in medical science from the University of Leipzig. In 1885 he was appointed to a professorial chair at the University of Basel, where he lived, researched and taught until his death.

Gustav von Bunge was an excellent scientist with an equivalent reputation who opted to remain

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in Basel although he was off ered professorships elsewhere. He is regarded as a trailblazer in many fi elds of physiological research : he laid the foun-dations for vitamin research, was a pioneer in the research of milk and mineral substances and he was among the fi rst to draw attention to the dan-gers of industrial sugar, alcohol and nicotine. To -day he is mainly only referred to in two contexts : the spinach issue, and his support of the temper-ance movement. After all, von Bunge believed that excessive consumption of alcohol could lead to damage of the genome.

A thought. One important discovery by Gustav von Bunge was the role of iron in nutrition. In the course of his research on milk he established that this fl uid actually contained very little iron (see the table above). However, as iron was already consid-ered to be a vital substance at the time, von Bunge did research on new-born animals, wondering where young animals got the important iron from. His con-clusions were astonishing, here too with reference to dry matter : in the case of mammals, the new-born animals get a large quantity of iron from their mother. Her depot is reduced in the fi rst weeks of their life, but it is suffi cient until the young animals are themselves capable of eating food containing iron. Von Bunge’s prime example were guinea pigs : they eat greenery immediately after they are born, which is why their supply of iron is so small.

It was for this reason that the physiologist ex -amined the iron content of diff erent food stuff s,

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publishing his fi ndings in a total of three succes-sive textbooks which were issued in several editions and languages. This was how his table with the iron values was disseminated. The scientist was not only a theorist, but was also very interested in practical application, which led him to make concrete sug-gestions about nutrition.

Von Bunge found out, for example, that white fl our contains very little iron : “ In addition to the poor iron content of milk there is the surprising fact of lack of iron in the most important vegetable foodstuff s, cereals [i. e. grains], at least in the form in which they are generally eaten, that is, with their seed coat removed, the so-called bran. When rice grain reaches the market the coat has already been removed ; it corresponds not to barley corn, but rather to pearl barley or white fl our for bread. When fl our is bagged the coat, the so-called bran, is separated from the fl our. […] The iron in cereals is contained in the coat. Wheat bran contains fi ve times as much iron as wheat fl our. ” For this reason, von Bunge advocated whole grain bread : “ Bran bread is four times better than white bread : 1. It contains more iron ; 2. It contains more calcium […] ; 3. It stimulates peristalsis thanks to its cellulose content […] ; 4. It cleans the teeth. ” He suggested meat as the main source of iron, plus vegetables : “ Apart from the above-mentioned, these include bran bread, potatoes, carrots, cabbage, and leg-umes. ” Von Bunge’s concerns illustrate the altered role of nutrition in industrial society : it was no

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longer defi ned in terms of hunger and satiety, shortage and stores, but also in terms of health.

Success : Von Bunge’s suggestions on nutrition became widely known. A claim made at a medical congress in 1895 should serve to illustrate this. One Professor Heubner stated : “ I can certainly say that I myself was very happy about having got to know the fi rst work by Mr. Bunge in this connection and I have followed all his studies with the greatest interest. Meantime I have come to realise that it is of extraordinary advantage to give young children even vegetables at an early age. In my own circle – where one has fi rst to gain people’s trust – I have sometimes met with the greatest astonishment in this connection when I have said to parents who consulted me : ‘ Give the child – which has perhaps 8 teeth – a spoon full of spinach or carrots or the likes every day. ’ I have done this on the basis of long and in-depth experience. Recently, recognition of the usefulness of this approach has also spread to Berlin. ”

Here – and von Bunge himself quotes that pro-fessor in his textbook – spinach achieved its unde-served fame through the backdoor, as it were, from the mouth of a fellow-researcher, given that von Bunge did not question the reference to spinach in this quotation. So he is not altogether innocent of the miseries experienced by so many children with spinach.

A thought experiment. But things could have been worse. After all, Gustav von Bunge did sug-

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gest another foodstuff as a source of iron – fortu-nately without much resonance : “ A little piece of blood sausage renders the same service. ” Just imagine, vanilla pudding with blood sausage. Bu.

� Bunge, Gustav von : Lehrbuch der Physiologie des Menschen. Leipzig 1905.

� Feron, Francois : Spinat enthält viel Eisen. In Bouvet, Jean-Francois et al (eds.) : Vom Eisen im Spinat und anderen populä-ren Irrtümern. Beliebte Volksweisheiten und kuriose Denk fehler unter die Lupe genommen. Munich 1999, pp. 183 – 186.

� Schmidt, Gerhard : Das geistige Vermächtnis von Gustav v. Bunge. Basel 1973.

� Winkler, Willi : Die grosse Spinat-Verschwörung. In Süddeut-sche Zeitung. Munich, 7 August 2010.

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“ This is such stuff as dreams are made of. ”

The discovery of LSD

If this is chance, then there is method in it : a labor-atory accident led to the discovery of the hallucin-ogenic eff ect of lysergic acid diethylamide (better known under the abbreviation LSD). On 16 April 1943 the chemist Albert Hofmann (1906 – 2008) returned to his laboratory at the pharmaceuticals company Sandoz in Basel after his lunch-break intending to continue his tests with that active agent. To do so, he had to produce the agent again in a process of synthesis. In the last phase of that synthesis it happened : Hofmann came in contact with the fl uid. At fi rst he did not notice anything, but in the course of the afternoon he felt somewhat strange and had to interrupt his work and go home, “ as I was befallen with a great unrest, plus a slight

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feeling of dizziness ”. At home he lay down and fell into a not unpleasant state similar to intoxication and marked by extremely agitated imaginative activity.

For two hours Albert Hofmann lived in a diff er-ent world. He recalled later : “ The outside world changed as if in a dream. Objects increasingly assumed the quality of a relief with unusual dimen-sions and colours became more brilliant. Even my self-perception and my feeling of time were altered. If I kept my eyes closed, I was overwhelmed by an uninterrupted stream of fantastic images of extra-ordinary plasticity and vivacity, accompanied by an intense kaleidoscopic play of colours. ” When Hofmann emerged from this state he immediately suspected poisoning. As the natural scientist in him was determined to get to the bottom of the surprising eff ect of the substance, the following Monday he began a self-test – and fortunately informed his laboratory assistant about his inten-tions.

A trip into the unknown. For although Hofmann swallowed only a tiny amount of LSD (0.25 mg), what then began was what would be called a hor-ror trip today. After about three-quarters of an hour the scientist became dizzy and nauseous and suff ered from visual disorders and bouts of laugh-ter. His head and hands felt cold, his throat dry, dis-turbing emotions alternated with feelings of numb-ness. Everything in his visual range fl uctuated and became distorted as if in a curved mirror.

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Hofmann just about managed to ride home on his bicycle, accompanied by his laboratory assist-ant. The woman next door brought him litres of milk as detoxifi cation, but he suddenly mistook her for an evil witch. The doctor who was called was baffl ed : pulse, blood pressure and breathing were normal, only the pupils were extremely dilated, and the chemist was incapable of formulating a single coherent sentence. Inside, Hofmann felt as if he were in the grip of a demon, powerless, alien. In the late evening he fell asleep exhausted – only to wake up the following day feeling like new : his breakfast tasted wonderful and the garden glittered and glowed in the sunlight. This extraordinary emo-tional state lasted all day long.

The miracle drug. The researcher was very sur-prised by the intense eff ect of such a tiny amount of the substance. Further self-tests followed, and then Sandoz also tested the substance in a series of experiments with animals. Subsequently, the chemists developed diff erent altered LSD products with no hallucinatory eff ect. The most eff ective of them was marketed as medication for treating migraine under the brand-name Deseril.

The use of LSD in psychiatry was much more consequential. The fi rst systematic use on people took place at the psychiatric clinic of the Univer-sity of Zurich in 1947. The pharmaceuticals com-pany sold LSD for psychiatric treatment and scien-tifi c research under the trade name of Delysid. The patient information leafl et recommends the medi-

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cation “ for mental unblocking in analytical psycho-therapy, especially in case of anxiety and compul-sive neuroses ”, but among possible fields of application mentioned were also “ experimental examinations of the essence of psychoses ”. In the 1950s it was believed that schizophrenia, depres-sion, alcoholism, arthritis and much more could be healed using LSD.

The sacrament of the Summer of Love. Over the years, however, instead of becoming a big seller for the pharmaceuticals company and a glorious chap-ter in the discoverer’s career, LSD became a prob-lem child – which is how Albert Hofmann put it himself in retrospect in 1979. After all, in the 1960s the substance mutated into a “ chemical sacra-ment ”, as one fan put it. Consuming drugs was part of the new lifestyle in the counter-culture in Amer-ica that grew out of the Civil Rights Movement and the protests against the Vietnam War. The aim was to reprogram the brain and liberate users from learned patterns, such as aggression, conventional thinking or poor self-estimation – through the use of psychedelic drugs. While this was still the priv-ilege of a relatively small circle of scientists and art-ists in the 1950s, now millions of Americans were gaining experience with LSD. Hippies, Hells Angels, rock musicians, they all wanted to try “ acid ”, as it was known in the jargon. The 1967 Summer of Love made LSD the ultimate party drug – at the same time forming the high point and the end of the LSD wave.

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“ The Politics of Ecstasy ”. Timothy Leary played a major role in this drugs culture facilitated by Hof-mann’s discovery. Leary was a military psychologist and doctor, who worked with alternative therapy methods in California. At fi rst he experimented with Psilocybin, a substance made out of Mexican mushrooms. But then a much more potent drug came on the market, LSD. Leary believed he had found the key to successful therapy, although his experiments can no longer be verifi ed. LSD eu -phoria, on the other hand, also leads to random consumption, horror trips and suicide attempts.

The result was considerable resistance in the form of a new anti-drugs policy. The substance was prohibited in the United States in 1966, and a few years later in Germany. Timothy Leary’s major con-fession of faith, his book The Politics of Ecstasy pub-lished in 1968, was on the index in Germany for 25 years. Leary himself was repeatedly arrested. He broke out of prison and, in 1971, sought political asylum in Switzerland, in vain. However, the Swiss authorities refused to deport him to the States.

A consciousness change with consequences. But that is not the end of the LSD story. The drug may not be addictive, but it is also not suitable for daily consumption, which is why its sales quickly declined after it was prohibited. Towards the end of the 20th century LSD gained in popularity again on the techno scene. Its impact on culture in the late 20th century however, is irreversible, at least according to the Legend of LSD, as the German

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author Günter Amendt called his critical review. Were the cultural revolution of the1960s, sexual lib-eration, the breakthrough for ecological thinking, the boom in pop music, really only due to the psy-chedelic power of LSD ? Would there be no com-puter revolution, no Internet, no Apple success story without LSD, as some convinced fans argue ?

LSD during the Cold War. LSD is certainly no normal substance. It has a special status, holding out the promise of religious, spiritual and sensual experience. What is more, it is not just a medica-tion and a drug, but potentially also a chemical weapon. As early as 1953, the CIA began its Mind Control Project, a decades-long series of tests with LSD aimed at fi nding out how healthy people reacted to the substance. The CIA is said to have wanted to order ten kilos of LSD from Sandoz for this purpose, a quantity suffi cient to send millions of people on a trip. The experiment was discontin-ued in the US in the 1970s under pressure from Congress.

In other western states too, similar tests were carried out with more or less voluntary candidates. Presumably the Warsaw Pact allies did compar able tests during the Cold War. The Czech pharmaceut-icals company Sposa produced LSD and exported it to the Eastern Bloc countries. GDR military hand-books describe possible uses of psycho-poisons like LSD in great detail.

Chance and sustainability. LSD was invented, or rather found, in Basel. Albert Hofmann’s discovery

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