imrt ve vmat hangi qamedikalfizik.org/uploads/files/14_mdf_kongre/1_gun...• tekrar hesaplama !!...

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IMRT - VMAT HANG İ QA YÜCEL SAĞLAM MEDİKAL FİZİK UZMANI

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Page 1: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

IMRT - VMAT HANGİ QAYÜCEL SAĞLAM MEDİKAL FİZİK UZMANI

Page 2: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hasta-spesifik QA ???

• Neden Hasta Spesifik QA ?

• Hangi Hasta Spesifik QA ?

• Hangi Hasta QA ekipmanı ?

• Hangi Hastaya ?

• Nasıl Değerlendireceğiz ?

Page 3: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Neden Hasta Spesifik QA?

• Data doğruluğu• Planlanan parametre = delivery

• Doz ? (mlc ) doğruluğu• Planlanan doz = delivery• Linak parametre - doz dağılımı

kontrolu?

• İlk fraksiyon ?• Set-up ?• Basit ekipman ?• Gerçek tedavi şartları ?• İnhomojenite phantom ?• Tekrar hesaplama !!• Zaman ?• RT process ?

•LOCAL TEST

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Gerçek Hasta QA ???

Hasta planı hybrid plan

Page 5: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi Hasta Spesifik QA ?• Pre-treatment QA

• On treatment, in vivo monitoring

• Post treatment

Page 6: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi Hasta Spesifik QA = Pre treatment qa

= Pre-treatment qa iki popüler yöntem• Per-beam dose verification

• Her alanda tek tek• Daha hızlı, kolay set-up• Hasta alan geometrisi farkli• Film,2-d array, epid, 3D

• Cumulative dose verification• Tüm alanların toplamı• Gerçek plana yakın• Tüm plan Point dose • Film, 2-d array, epid, 3D

Page 7: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi Hasta Spesifik QA ?• Tek bir hasta kontrolü- Tek fraksiyon ?

• iki yöntemin kendi arasındaki farkları ?

• Kullanılan ekipmana göre farklı sonuçlar?

• Her yöntem IMRT ve VMAT yöntemi desteklemiyor

Page 8: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi Hasta Spesifik QA ?• Tüm planın toplam dozu ?

• Per-beam dose verification

• Cumulative dose verification

• Imrt-Vmat için ayrı pre-treatment yöntemi ?

• Imrt için Per-beam / Cumulative dose verification

• VMAT için Cumulative dose verification

• Kullanılan yönteme göre plan nasıl değiştirilecek ?

• Hatalı alan? (Per-beam dose verification)

• Tüm plan ? (Cumulative dose verification)

Page 9: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipmani ?

Hasta spesifik QA

+ Pre-treatment QA

+ Cumulative dose verification

Page 10: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipmani?

• 0 boyutlu• İyonizasyon odası • Diyotlar • TLD

• 1 boyutlu• Stack of TLD chips • Linear array detectors

• 2 boyutlu• Film• EPID EPID • 2D-Array

• 3 boyutlu• Gel• 2 perpendicular diode

array• Arc-check• 4d monte carlo simulation

Hasta spesifik QA-Pre-treatment QA-Cumulative dose verification

Page 11: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device
Page 12: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipman ?Single field isodose

• İyon odası fizikselözellikler?• Non coplanar field ?

• Point absolut dose ?

• IMRT isodose gradient ?

Intensity modulated field

Page 13: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipman ?

Page 14: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipman ?

Page 15: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipman ?

Page 16: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

• İyon odası• point dose ?

• Film dozimetri• Kalibrasyon ?• Prosedür ?

• EPID• Kalibrasyon ?• Correlation factor ?

• 2-Array • resolution ?• İyon-diyot ?

• 3D array• 2D array göre ektra zaman !• Karışık sonuçlar !

Hangi QA ekipmanı ?

Page 17: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi QA ekipman ?Jonathan G. Li and et al, Comparison of two commercial detector arrays for IMRT quality assurance Journal of applied clinical medical physics, vol 10,no 2 spring 2009

Stefan Both and et al, A study to establish reasonable action limits for patient specific IMRT QA, Journal of applied clinical medical physics, vol 8, no 2 2007

Litaratürde kesin bir sey yok !!

Daniel A. Low et al, Dosimetry tools and techniques for IMRT. Med. Phys. vol38:no 1313 – 1338,2011

Page 18: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Hangi Hastaya ?

• SBRT

• SRS

• Kompleks vakalar

• Palyatif veya 3D yapilabilecek

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SBRT-SRS+Hasta Spesifik QA

Page 20: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Kompleks vakalar+Hasta Spesifik QA

Page 21: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Palyatif veya 3D yapılabilecek vakalar

Hasta Spesifik QA ?

Page 22: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Nasıl Değerlendireceğiz ?

• GAMA index-analiz?• ACTION LIMIT nedir?

• Vakaya göre • Kullanılan ekipmana göre

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GAMA index-analiz ?

>90% of all surveyed use 3%/3mm or greater

Page 24: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Nasıl Değerlendireceğiz ?

Page 25: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

GUIDELINES FOR THE VERIFICATION OF IMRT 2008 by ESTROBecause of the special shape and delivery of IMRT fields, it is not a priory certain that ionisation chamber measurements can be analysed using the procedures outlined in existing dosimetry protocols. In Section 3.1 theresults of some studies are presented yielding information on the use of ionisation chambers,and some other detectors, in IMRT fields.

this moment it is, however, not yet clear to which extent the methods presented in this booklet may also be applied for the verification of 4DIMRT.

At this moment it is not yet clear to what extent multiple 2D analysis is sufficient or a complete 3D verification is required.

Verification of IMRT delivery in a phantom does not provide informationabout the actual dose delivered to a patient, which requires an in vivo approach.

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As a final remark it should be noted that it is important, but sometimes difficult, to determine if discrepancies between measured and planned dose distributions are caused by the treatment planning system, the data transfer, the treatment unit, the measurement device or the data analysis.

GUIDELINES FOR THE VERIFICATION OF IMRT 2008 by ESTRO

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Hasta Spesifik QA yeterli ?Guanghua Yan and et al, On the sensitivity of patient-specific IMRT QA to MLC positioning errorsJournal of applied clinical medical physics, vol 10,no 1 2009

However, considering the significant dosimetric effect such MLC errors could cause,patient-specific IMRT QA should be combined with a periodic MLC QA programin order to guarantee the accuracy of IMRT delivery.

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Hasta QAData doğruluğuDoz doğruluğu

Periyodik QA

Makina spesifik QA

MLC doğruluğuLinac doz doğruluğu

End to end test

Doz doğruluğuRt process

Mu calculation software

Tps kontrolR&V Data doğruluğu

DynaLog MLC Files

MLC doğruluğu

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Hasta spesifik QA

Periyodik QA

Page 31: IMRT VE VMAT hangi QAmedikalfizik.org/uploads/files/14_MDF_Kongre/1_gun...• Tekrar hesaplama !! ... • Per-beam dose verification ... the treatment unit, the measurement device

Teşekkürler.......