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Integrity : NAFLD의 타겟 탐색 이경미 Clarivate Analytics Life Science Consultant 2019. 06. 13

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Page 1: Integrity · 2020-01-03 · Details Ref. I Ref. 1 Activity Farnesoid receptor activation, induction Farnesoid receptor activation, induction FXR FXR Model COS monkey kidney cells

Integrity :

NAFLD의타겟탐색

이경미Clarivate AnalyticsLife Science Consultant

2019. 06. 13

Page 2: Integrity · 2020-01-03 · Details Ref. I Ref. 1 Activity Farnesoid receptor activation, induction Farnesoid receptor activation, induction FXR FXR Model COS monkey kidney cells

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Agenda

• Integrity 소개

• 데모를통한타겟검색

• 관심질환의 Targetscape 검색

• 타겟관관련된의약품개발현황

• 비슷한구조의의약품, 차이점은?

Page 3: Integrity · 2020-01-03 · Details Ref. I Ref. 1 Activity Farnesoid receptor activation, induction Farnesoid receptor activation, induction FXR FXR Model COS monkey kidney cells

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Integrity 란?

• 의약품 R&D 데이터베이스 – For Scientist, By Scientist

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Demo를통한검색

• 관심질환의 Target landscape 검색 – Non-alcoholic fatty liver disease (NAFLD)

• Target의의약품현황은? – Development

• 비슷한구조의의약품, 차이점? – Structure similarity

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Summary: 관심질환의 Targetscape 검색

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Page 7: Integrity · 2020-01-03 · Details Ref. I Ref. 1 Activity Farnesoid receptor activation, induction Farnesoid receptor activation, induction FXR FXR Model COS monkey kidney cells

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Summary: Target 과관련된현재의약품개발현황

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Page 9: Integrity · 2020-01-03 · Details Ref. I Ref. 1 Activity Farnesoid receptor activation, induction Farnesoid receptor activation, induction FXR FXR Model COS monkey kidney cells

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Summary: 비슷한구조의의약품, 차이점은?

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