MANSONELLA PERSTANS

GD: Tropical Africa, Central and Eastern South America, Central America & Caribbean.Pathogenesis: MansonellosisHabitat: Body Cavities (peritoneal cavity or pleural cavity)Vector: Culicoides sp. (female/biting midges)

EPIDEMIOLOGY

MORPHOLOGY Microfilaria

200 μm in length; width of 4.5  μm; have the ability to elongate and contract (can vary in measurement and form)

unsheathed nuclei extend to the end of the blunt tail head spot sometimes has a V-shaped

appearance Adult

white and thread-like cylindrical in shape Male

45 mm by 60 μm; tail is full coil Female

70-80 mm in length; 120 μm in diameter

LIFE CYCLE

MANIFESTATION often asymptomatic (no symptoms

shown) associated with angioedema, pruritus,

fever, headaches, arthralgias, and neurologic manifestations.

eosinophilia, headache, fever, or abdominal pain may also be present

nodules in conjunctiva (kampala or Ugandan eye worm) 

microscopic examination blood samples antigen detection

DIAGNOSIS

TREATMENT

albendazole and mebendazole combination treatments of diethylcarbamazine

and mebendazole doxycycline