marc d. riedel associate professor, ece university of minnesota ee 5393: circuits, computation and...
TRANSCRIPT
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Marc D. RiedelAssociate Professor, ECE University of Minnesota
EE 5393: Circuits, Computation and BiologyEE 5393: Circuits, Computation and Biology
ORAND AND
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Instructor
Prof. Marc Riedeltel.: (612) 625-6086email: [email protected] office: EE/CSi 4-167
office hours: Th. 1:00–3:00pm
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Teaching Assistants
Joshua Kristemail: [email protected]: Keller Hall 4-136
office hours: after every graded homework is returned
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EE5393: Circuits, Computation, and Biology
• Lecture: Wed. & Friday, 2:30–3:45pmLocation: Keller Hall 3-230
• Prereqs: none • Textbooks: none• Website: http://tinyurl.com/ee5393
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Grading
• 20% Quizzes:11 quizzes
(best 10 of 11 scores)
• 80% Homeworks:5 homeworks
(best 4 of 5 scores)
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“A person's mental activities are entirely due to the behavior of nerve cells, glial cells, and the atoms, ions, and molecules that make them up and influence them.”
– Francis Crick, 1982
Astonishing Hypothesis
“That the astonishing hypothesis is astonishing.”
– Christophe Koch, 1995
The Astonishing Part:
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Domains of Expertise
• Vision• Language• Abstract Reasoning• Farming
Human
Circuit
• Number Crunching
• Mining Data• Iterative
Calculations
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Circuits & Computers as a Window into our Linguistic Brains
CircuitBrainConceives of circuits and
computation by “applying” language.
Lousy at all the tasks that the brain that
designed it is good at (including language).
?
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Language as a Window into the way the Brain Works
Steven Pinker, Harvard
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“Minnesota Farmer”
• Most of the cells in his body are not his own!
• Most of the cells in his body are not even human!
• Most of the DNA in his body is alien!
Who is this guy?
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“Minnesota Farmer”
• 100 trillion bacterial cells of at least 500 different types inhabit his body.
Who is this guy?
He’s a human-bacteria hybrid:
vs.
• only 1 trillion human cells of 210 different types.
[like all of us]
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“Minnesota Farmer”
Who is this guy?What’s in his gut?
• 100 trillion bacterial cells of at least 500 different types inhabit his body.
He’s a human-bacteria hybrid:
vs.
• only 1 trillion human cells of 210 different types.
[like all of us]
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About 3 pounds of bacteria!
What’s in his gut?“E. coli, a self-replicating object only a thousandth of a millimeter in size, can swim 35 diameters a second, taste simple chemicals in its environment, and decide whether life is getting better or worse.”
– Howard C. Berg
flagellum
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Bacterial Motor
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Bacterial Motor
Electron Microscopic Image
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“Stimulus, response! Stimulus response! Don’t you ever think!”
We should put these critters to
work…
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Artificial Life
US Patent 20070122826 (pending):“The present invention relates to a minimal set of protein-coding genes which provides the information required for replication of a free-living organism in a rich bacterial culture medium.” – J. Craig Venter Institute
Going from reading genetic codes to writing them.
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Artificial Life
Going from reading genetic codes to writing them.
Moderator: “Some people have accused you of playing God.”
J. Craig Venter:“Oh no, we’re not playing.
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