1

بسمه تعالی

شغلی سابق علمی

مشخصات فردی

آزاد خالذیبم بم خبادگی:

51/2/5131تبسیخ تلذ:

یهلیت: ایشا

دعتبىهحل تلذ: کش

55541112-31-98+ تلفي:

:آدسط الکتشیک

Azadkh99@gmail.com

Khaledi-a@kaums.ac.ir

سابق تحصیلی

35-31داؾگب علم پضؽکی عذج، ،آصهبیؾگبیکبسدای علم *

،جذی ؽبپس ااص* کبسؽبعی علم آصهبیؾگبی، داؾگب علم پضؽکی

38-38 کبسؽبعی اسؽذ هیکشة ؽبعی پضؽکی، داؾکذ پضؽکی، داؾگب علم *

31-15پضؽکی تشاى،

2

ؾگب داؾکذ پضؽکی، دا( ثبکتشی ؽبعی پضؽکی، PhD* دکتشای تخصصی)

15-11 .علم پضؽکی هؾذ

پایان وام ا

اتخبثی دس mfs efflux pumpsفشاای اسصیبثی : ارشذپبیبى به کبسؽبعی

ثغتشی دس ایضل بی ثبلیی اعیتثبکتشثهبی جذا ؽذ اص ثیوبساى

ICU. ثخؼ

hpaA-CagA صایی ژى فیژىثشسعی ایوی (:PhD)تخصصی پبیبى به دکتشای

. BALB/Cلیکثبکتش پیلسی کلیشاظ آى دس هذل هؽی

پژشی –علمی سابق:

ای داخلی بیه المللی ارائ خالص مقاالت در کىگري

ثیوبساى دس اسپبتژى کلی اؽیشیؾیب ثیتیکی آتی هقبهت الگی

ثیي کگش الیي هلی کگش ؽؾویي، 5111-5115عبل دس کشج عشپبیی .هؾذ پضؽکی علم داؾگب ثبلیی، ؽبعی هیکشة للیالو

ثبکتش اعیت ثبلیی بی ایضل ثیي ثیتیک تیآ هقبهت الگی ثیوبسعتبى هختلف بی ثخؼ دس دیغک اتؾبس سػ اص اعتفبد ثب ثهبی

دهیي عشاعشی کگش عیضدویي ،5111-5115 عبل دس گلغتبى اعتبى هطشی .اسدثیل پضؽکی علم داؾگب ایشاى، ؽبعی هیکشة للیالو ثیي کگش

ؽیذ پضؽکی علم داؾگب دس ثبلیي آصهبیؾگب کگش چبسهیي دس ؽشکت

.12/11/5111، ثؾتی

ثیوبسعتبى دس بف ثذ خى بی و ثبکتشیبیی آلدگی هیضاى ثشسعی

بی هقبهت ب عفت داؾجیی کؾسی کگش1390 عبل دس تشاى ؽشیعتی

.گیالى، لگشد –1391هب اسدیجؾت داسییی

Hossein Saghi, Davoud Esmaeili, Abbas Bahador, Azad Khaledi, Ferdoes Amiri Dastjerdi,

Study of expression of the gene aphA6 in multidrug -resistant Acinetobacter baumannii

against Thyme essence with Real Time PCR, Tehran,15th

International Congress of

Microbiology,2014.

بی ثشسعی بپبستیکلPLGA ایوتشاپی اختصبصی، کگش ثیي

5111، داؾگب علم پضؽکی هؾذ دس عبل آلشژی الوللی آعن

:سخىراوی درکىگري ا

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Study of bacterial infection in patients receiving kidney transplant, Mashhad, Iran

(International congress, Mashhad, 2015).

:سابق شغلی

ؾگب تبثع دا بی گزساذى طشح یشی اغبی دس ثیوبسعتبى

علم پضؽکی

بی:علوی هقبالت دس ژسبل داس

The Navid No Journal

Journal of Research in Medical Sciences

American Journal of Infection Control

Gene Report

International Archives of Health Sciences

:سابق تذریس

پضؽکیسؽت بی ؾجیبى داتئسی ظشی ط هیکشة ؽبعی دس،

داؾگب علم پضؽکی ، هبهبیی، تغزی علم آصهبیؾگبیدذاپضؽکی

کبؽبى.

بعی عولی تؾخیصی هلکلی داؾجیبى کبسؽبعی اسؽذ ثبکتشی ؽ

کبؽبى. داؾگب علم پضؽکی دکتشی تخصصی

.ىکبؽب داؾگب علم پضؽکی دکتشی تخصصی هیکشة ؽبعی دبى دذاى.

.داؾجیبى دکتشی ثبکتشی ؽبعی ثبکتشی بی ثی اصی عخت سؽذ

.کبؽبى داؾگب علم پضؽکی تخصصی

.داؾگب علم پضؽکی داؾجیبى دکتشی تخصصی هجبی پبتژغیت

.کبؽبى

4

.داؾگب داؾجیبى دکتشی تخصصی ثبکتشی ؽبعی عیغتوبتیک پیؾشفت

.کبؽبى علم پضؽکی

تی مصب اتمام یافتای تحقیقا طرح:

ثشسعی ثیبىMFS Efflux Pumps بی اعیتثبکتشثهبی اتخبثی دس ایضل

5111-5115، هجشی طشح، RT-PCRث سػ ICUجذا ؽذ اص ثخؼ

بی ای دسصذ علل ثشسعی هقبیغT Regulatory دس خى هحیطی افشاد هجتال ث

5131-5111ثشعلص افشاد عبلن، وکبس طشح،

ثشسعی تأثیشهخلط اعبظ بی گیبیOriganum vulgare،Zataria multiflora

Satureja khuzestaniea ثشسی ثیبى ژى بی هقبهت آتی ثیتیکیbla-OXA-23

aphA6 ایضل بی ثبلیی آعیتثبکتش ثهبی ثیوبسعتبى بی هتخت

. Real-Time PCRتشاى ث سػ

صایی ژى فیژىثشسعی ایوی hpaA-CagA لیکثبکتش پیلسی کلیشاظ آى

BALB/Cدس هذل هؽی

آیؾي عغل ثش ایضل بی ثشسعی تبثیش اعبظ بی داسچیي ،

عدهبط exoS ampCهقبم ث چذ داس ثیبى ژى بی

آئشژیصا جذا ؽذ اص عفت عختگی

در حال اوجامای تحقیقاتی طرح:

هقبم ث UPEC) ثشسعی هیضاى فشاای غجی ایضل بی اسپبتژى) *

(، ایتگشى کالط یک تؾکیل ثیفیلن دس ایضل بی MDRچذ داس)

( افشاد هشاجع کذ ث ثیوبسعتبى ؽذای UTIجذاؽذ اص عفت ادساسی)

قن

هلذ کلجغیال پهیبی ثبلیی ثشسعی تبیپیگ هلکلی ایضل*

( جذا ؽذ اص ثخؼ بی هختلف ESBLثتبالکتبهبصبی عیع الطیف)

(PFGE)ثیوبسعتبى ثؾتی کبؽبى ثب سػ پبلظ فیلذ ژل الکتشفسصیظ

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- هیضاى ثش تؾکیل ثیفیلن قش اکغیذ سی اتبرس اثشثشسعی *

اعتبفیلککط اسئطدس ica Aثیبى ژى

ی( آتیفیلوی ث یکپالکت)بیی ثبکتشی یاثشات آت یثشسع*

اتشککط ( ثش یذاع اعیک) ب­گلغگ یثب یتهتبثل یذایاکغ

یغیيهقبم ث کهب یظفکبل

تالیف ترجم کتاب

شذي مىتشرای کتاب

ثذاؽت دعت دس هشاکض اسائ خذهبت دسهبی عشپبیی، هشاقجت دس (5

اتؾبسات .هضل هشاکض گذاسی اص عبلوذاى ثیوبساى هضهي

. 5118تشجوبى خشد. عبل

عبل .اتؾبسات علم فى هعیي ، هیکشة ؽبعی دبى دذاى (2

5111.

عبل .لم فى هعیياتؾبسات ع هیکشة ؽبعی عوهی تخصصی، (1

5113 .

ضذ عفی آهبد عبصی اثضاس تجیضات پضؽکی دس هشاکض دسهبی (8

.5113 ثذاؽتی. اتؾبسات ی گبس. عبل

تکىیکای ملکلی با تسلط کافی

1. PCR

2. RT-PCR

3. Real-Time-PCR

4. Cloning of genes

5. Expression of genes

6. Purification of proteins (Chromatography)

7. SDS-PAGE

8. Western blot

9. Cell culture

10. Eliza test

11. Transformation

12. Extraction of DNA, RNA and Plasmid

13. Dialysis

14. cDNA synthesis

15. Gel electrophoresis

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با تسلط وسبی یافسارای بیاوفرماتیک ورم

1. Gene runner

2. Primer premier

3. Beacon designer

4. Bio-edit

5. Mega

6. Primer plex

7. CMA (Comprehensive meta-analysis).

8. Gene Discover

9. Gene Designer

10. Mfold

11. JCAT

12. Graph Pad

چاپ شذي مقاالت

1. Clonal lineages and virulence factors among Acinetobacter baumannii isolated from Southwest of Iran.

J. Pure Appl. Micribiol. 7, 1559-66.

2. Evaluation of antibacterial properties of nano silver Iranian MTA against Fusobacterium nucleatum.

European Journal of Experimental Biology 3 (6), 88-94.

3. Phylogenetic relationships among Staphylococcus aureus isolated from clinical samples in Mashhad,

Iran Journal of infection and public health.

4. Antibiotic susceptibility pattern and identification of extended spectrum β-lactamases (ESBLs) in

clinical isolates of Klebsiella pneumoniae from Shiraz, Iran. Iranian Journal of Microbiology 8 (1), 55.

5. The Proteins of Type IV Secretion System as Promising Candidates for Helicobacter pylori Vaccine.

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6. The Prevalence of ISAba1 and ISAba4 in Acinetobacter baumannii Species of Different International

Clone Lineages Among Patients With Burning in Tehran, Iran. Jundishapur journal of microbiology 8 (7).

7. Antibacterial Effects of Origanum vulgare Essence against Multidrug-Resistant Acinetobacter

baumannii Isolated from Selected Hospitals of Tehran, Iran. Avicenna Journal of Clinical Microbiology

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8. Photocatalytic Effects of Acrylic Resins Incorporated with Nano-titanium Dioxide on Planktonic and

Biofilm Growth of Four Cariogenic Bacteria. Annual Research & Review in Biology 4 (17), 2695.

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9. Study of expression of the gene alpha-6 in multidrug-resistant acinetobacter baumannii against thyme

essence with real time PCR . Iranian Journal of Public Health 43 (2), 36.

10. An in vitro assessment of the antibacterial properties of nanosilver Iranian MTA against

Porphyromonas gingivalis. Journal of Chemical & Pharmaceutical Research 5 (10).

11. Evaluation the Accuracy of drug susceptibility testing by disk diffusion method in Medical diagnostic

Laboratories of Hamedan University of Medical Sciences. Der Pharma Chemica, 2016, 8(4):14-19.

12. Prevalence of Extended-Spectrum-β-Lactamase-producing Escherichia coli isolates among

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14. Prevalence of Extended-Spectrum-β-Lactamase-producing Escherichia coli isolates among

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15. Prevalence and types of bacteria associated with neonatal sepsis in neonatal ward from Ghaem

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16. In vitro evaluation of MFS efflux pumps among multidrug resistant Acinetobacter baumannii isolated

from patients hospitalized in ICU. Der Pharma Chemica, 2016, 8(1):104-110.

17. Expression of MFS efflux pumps among multidrug resistant Acinetobacter baumannii clinical

isolates. Der Pharmacia Lettre, 2016, 8 (2):262-267.

18. The role of HPaA protein as candidate vaccine against Helicobacter pylori. Der pharma letter. Jan

2016.

19. Cloning, Expression and Purification of HpaA Recombinant Protein of H. pylori as a Vaccine

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20. Identification of Pathogenic Bacteria in Blood Cultures and Susceptibility Testing of Isolates with

Various Antibiotics. Avicenna J Clin Microb Infec . 2016 June 15.

21. Prevalence of Nontuberculous Mycobacteria isolated from environmental samples in Iran; A meta-

analysis. Journal of Research in Medical Sciences.

22. Determination of antimicrobial resistance pattern of Acinetobacter baumannii isolated from patients in

intensive care unit (ICU) .Medical Journal of Mashhad University of Medical Sciences.

23. Prevalence of Nontuberculous Mycobacteria (NTM) in Iranian Clinical Specimens: Systematic

Review and Meta-Analysis. J Med Bacteriol.

24. Prevalence of Cep Gene of Brucella isolated from Clinical Specimens in Hospitals from Kermanshah

of Iran.

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25.Expression, Purification and Characterization of the Mixed Total -OMP- CagA from Brucella abortus

and Helicobacter pylori as Vaccine Candidate.

26. Prevalence of nosocomial infection in different wards of Ghaem hospital, Mashhad. Avicenna Journal

of Clinical Microbiology and Infection.

27. Increasing trend of imipenem–resistance among Acinetobacter baumannii isolated from hospital

acquired pneumonia in northeast of Iran. Journal of Pharmacy and Bioallied Sciences.

28. Prevalence of Legionella Species in Water Resources of Iran: A Systematic Review and Meta-

Analysis. Iranian Journal of Medical Sciences.

29. Relationship between antibiotic resistance with spa gene polymorphism coding protein A and its

typing with PCR-RFLP technique in S. aureus isolated from foodstuffs.

30. The study of inhibitory effects of Satureja khuzestanica essence against housekeeping fabD and exoA

genes of Pseudomonas aeruginosa using RT-PCR technique. Asieh Abbasi, Arash Mahboubi, Azad

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31. The Prevalence of virB2 and 16SrRNA Genes of Brucella Isolated from Clinical Samples of

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32. Prevalence of HBsAg and Associated Risk Factors with Hepatitis B Infection among Pregnant

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33. Evaluation of the Sero-epidemiology of Toxoplasma gondii in Patients Visiting Ghaem Hospital,

Mashhad, Iran. Navid Journal.

34. Study of drug resistance of Staphylococcus aurous and Pseudomonas aeruginosa strains isolated from

environmental samples of Hamadan educational hospitals in 2017 using disk diffusion and minimum

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35. The Prevalence of virB2 and 16SrRNA Genes of Brucella Isolated from Clinical Samples of

Hospitals, Western Iran. Iran J Public Health.

36. Mutations of rpob Gene Associated with Rifampin Resistance among Mycobacterium Tuberculosis

Isolated in Tuberculosis Regional Reference Laboratory in Northeast of Iran during 2015-2016 Citation.

Ethiopian journal of health sciences.

37. Molecular Detection of Virulence Genes of Salmonella gallinarum from Iranian Poultry. Journal of

Research in Medical and Dental Science.

38. Identification and Isolation of Mycobacterium tuberculosis from Iranian Patients with Recurrent TB

using Different Staining Methods .Journal of Research in Medical and Dental Science.

39. Study of serum bactericidal and splenic activity of Total-OMP- CagA combination from Brucella

abortus and Helicobacter pylori in BALB / c mouse model. Microbial Pathogenesis.

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40. The pattern of antibiotic resistance of common bacteria causing nosocomial infections. World Family

Medicine/Middle East Journal of Family Medicine.

41. Distribution of Human Papilloma Virus-16 E7 oncoprotein in Iranian Patients with Cervix Cancer.

Journal of Research in Medical and Dental Science.

42. Prevalence of Catheter-associated bacteriuria in patients who received short-term catheterization in

the northeast of Iran. Novelty in Biomedicine.

43. Study of Bacterial Infections Among Patients Receiving Kidney Transplant in Mashhad, Iran.

Experimental and Clinical Transplantation (2017).

44. Relationship Between Antibiotic Resistance with Spa Gene Polymorphism Coding Protein A and its

Typing with PCR-RFLP Technique in S. aureus Isolated from Foodstuffs. Avicenna J Clin Microbiol

Infect.

45. Investigate the Inhibitory Effects of Satureja khuzestanica Essential Oil against Housekeeping fabD

and exoA Genes of Pseudomonas aeruginosa from Hospital Isolates using RT-PCR Technique. Annals of

Medical and Health Sciences Research.

46. Prevalence of ESBLs in Acinetobacter baumannii isolated from intensive care unit (ICU) of Ghaem

hospital, Mashhad, Iran. Journal of Pure and Applied Microbiology.

47. Prevalence of Nosocomial Infection in Different Wards of Ghaem Hospital, Mashhad. Avicenna J

Clin Microbiol Infect.

48. Urinary tract infections in kidney transplant recipients 1 year after transplantation. Journal of

Research in Medical Sciences.

49. Evaluate the Relationship between Class 1 Integrons and Drug Resistance Genes in Clinical Isolates

of Pseudomonas aeruginosa. The Open Microbiology Journal.

50. Study of Satureja Khuzestanica essential oil against quorum sensing of Pseudomonas aeroginosa

using RT- PCR. Iran J Public Health.2017.

51. Tuberculosis Status and Coinfection of Pulmonary Fungal Infections in Patients Referred to Reference

Laboratory of Health Centers Ghaemshahr City during 2007-2017 . Ethiopian Journal of Health

Sciences.2018.

52. Antimicrobial resistance pattern of Acinetobacter baumanii isolated from patients in intensive care

unit of Imam Khomeini hospital, Tehran. Journal of Gorgan University of Medical Sciences. 2018.

53. Evaluation of the Prevalence of Nosocomial Infection in Different Wards of Be’sat Hospital of

Hamedan. Avicenna J Clin Microbiol Infect.2018.

54. Study on the killing effect of cold atmospheric pressure plasma on MRSA Staphylococcus aureus in

vitro and in vivo infection model. Malaysian Journal of Microbiology. 2019.

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55. Study of virulence genes and related with biofilm formation in Pseudomonas aeruginosa isolated

from clinical samples of Iranian patients; A systematic review. Gene Reports. 2019.

56. Alerting prevalence of MBLs producing Pseudomonas aeruginosa isolates. Gene Reports. 2019.

57. Satureja khuzestanica Essential Oil against Quorum Sensing of Pseudomonas aeroginosa Using RT-

PCR. Iran J Public Health.2019.

58. Molecular detection of antibiotic resistance genes, and class I, and II integrons in Salmonella

enteritidis isolated from Iranian one-day-old chicks. Gene Reports. 2019.

59. Epinecidin-1, a highly potent marine antimicrobial peptide with anticancer and immunomodulatory

activities. BMC Pharmacology and Toxicology.2019.

60. Cloning, expression, and purification of HpaA-CagA fusion recombinant protein of Helicobacter pylori

in E. coli BL 21 strain. Gene Reports. 2019.

61. Evaluation of the prevalence of Legionella pneumophila in Iranian clinical samples: A systematic

review and meta-analysis. Microbial Pathogenesis.2019.

62. Vaccine potential of LenA and LcpA proteins of Leptospira interrogans in combination with

Escherichia coli heat-labile enterotoxin, B subunit (LTB. Iranian Journal of Microbiology.2019.

63. Prevalence of Linguatula serrata Nymphs in Goats Slaughtered in Mashhad Slaughterhouse, Iran.

Avicenna Journal of Clinical Microbiology and Infection. 2019.

64. Study of inhibitory effects of the mixture of cinnamon and ginger extracts on cagA gene expression

of Helicobacter pylori by Real-Time RT-PCR technique. Gene Reports. 2019.

65. A meta-analysis of the prevalence of class 1 integron and correlation with antibiotic resistance in

Pseudomonas aeruginosa recovered from Iranian burn patients. Journal of Burn Care & Research.2019.

66. Inhibitory Effects of a Herbal Ointment against Pseudomonas aeruginosa. Medical Laboratory

Journal. 2019.

67. Prevalence of Legionella Species in Water Resources of Iran: A Systematic Review and Meta-Analysis.

2018. Iran J Med Sci.

68. Tuberculosis Status and Coinfection of Pulmonary Fungal Infections in Patients Referred to

Reference Laboratory of Health Centers Ghaemshahr City during 2007-2017. Ethiop J Health Sci. 2018.

69. Prevalence of Integrons and Antibiotic Resistance Pattern in Acinetobacter baumannii Isolated from

Clinical Samples of Iranian Patients; A Systematic Review and Meta-analysis. Ethiopian Journal of Health

Sciences.2019.

70. Investigation of prevalence and antibiotic resistance pattern of bacteria isolated from urinary tract

infections in women referred to Ghaem hospital in Mashhad. Feyz. 2019.

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مقاالت اکسپت شذي

71. Specific Diagnosis of Chlamydia trachomatis as an Agent of Sexually Transmitted Disease using a

Molecular Method. Iran J Public Health.

72. A Systematic Review of the Effects of Satureja Khuzestanica Jamzad and Zataria Multiflora Boiss

against Pseudomonas Aeruginosa. Iran J Med Sci.

73. Reduced efflux pumps expression of Pseudomonas aeruginosa with Satureja khuzistanica Essential

oil. Iran J Med Sci.

74. Study of MBL producing Acinetobacter baumannii isolates and detection of its related IMP gene by

molecular method. Iran J Public Health.

75. Study of Urinary Tract Infection Caused by Bacterial Pathogens and Their Pattern of Antibiotic

Resistance among Iranian Patients Who Receive the Kidney Transplant: A Systematic Review and Meta-

Analysis. Iran J Public Health.

76. Pulmonary mycoses co-infection among Iranian patients with clinically suspected cases of pulmonary

tuberculosis. Iran J Public Health.

77. Antimicrobial effect of Opuntia ficus-indica extract on Escherichia coli isolated from patients with

urinary tract infection. Iran J Public Health.

78. Molecular typing of Clinical isolates of Acinetobacter baumannii using random amplified

polymorphic DNA (RAPD-PCR). Iran J Public Health.

79. Efficacy of PCR analysis of mip, dotH and gspD genes with culture in detection of Legionella

pneumophila. Iran J Public Health.

80. Diagnosis of Acute Toxoplasmosis by IgG Avidity Method in Pregnant Women Referring to

Therapeutic and Health Centers of Mashhad University of Medical Sciences. Iran J Public Parasitol.

81. Construction, cloning and expression of CagA recombinant protein of Helicobacter pylori. Avicenna

Journal of Medical Biotechnology.

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