orientalcosmetics - repository.kisti.re.kr · 안전성 무자극,무allergy등...
TRANSCRIPT
. TCI Report
KISTI
. , ,⋅ ⋅
, .
2006 TCI
S/W⋅
⋅
⋅
⋅
. 2005 3,300
.
,
.
(KISTI)
· ( )
.
, .
.
.
,
,
.
,
,
.
2008 10
Table of
72 2.
< I-2> ··················································10
< I-4> ········································13
< I-5> ····································15
< II-1> ··30
< II-2> ········34
< II-3> ······················40
< II-4> ··········48
< II-5> ··50
< II-6> ························52
< II-7> ········54
< II-8> ········55
< II-9> ········································55
< II-10> ··········56
< II-11> ························66
< III-1> ·········69
< III-2> ·····························70
< III-3> ···············85
< III-4> ·································88
< III-5> ·································89
< III-6> 5 ······················89
< I-2> ·······················7
< I-3> ·····································8
< I-4> ········································12
< I-5> ······························16
< I-6> ··································18
< II-1> ···························56
< II-2> ·····································60
< II-3> ···················································61
< II-4> ·················································62
< II-5> ·············································63
< III-1> ·······································72
< IV-1> ·······························93
< IV-2> ·······································94
< IV-3> ·························································96
< IV-4> ··········97
< IV-5> ······················98
I
.
/ /
.
,
,
.
( , , ,
, , , , , , ,
) 11 ,
,
.
, .
,
,
.
< -1>
.
.
, , ,
.
, , , , , , , ,
, .
, , , ,
.
,
,
.
, ,
,
,
.
.
,
.
,
. “
Technology Commercialization Intelligence Report
” 3 1).
(1)
, .
,
“ ” , ,
.
(2)
, , , , ,
.
(3)
.
06
,
30 2 5 ,
: , , , 2005, , p. 117
) : 1 2
: 30 40 ,
.
, , ,
, , ,
Collagen .
KISTI
, (<
-3)>.
< -3>
QC
, , ,
,
, , , ,
, ,
Finger printing ,
, ,
, , ,
, NT
.
(capsulation) ,
DDS(drug delivery system)
. ,
,
, .
(liquid crystal) 1
, (patch) , (lamella liquid
crystal) , (multiple emulsion) .
DDS(drug delivery system) ,
,
, ,
(emulsion) .
( )
,
(collagen , cytokine , mRNA
) .
,
. ,
,
.
, replica
, ,
( < -3>) .
010
, , ,
, ,
< -3>
Dermaspectrometer,mexameter
Collagen Fibroblasts
Titro processor
( )
In vitro in vivo ( )
.
, ,
,
.
( )
In vitro in vivo ( )
.
, ,
,
.
In vitro in vivo
( ) .
, ,
.
012
( ) Collagen
( ) in vitro
Collagen .
, ,
.
,
, , ,
.
< -4>
: , , 2007. 4
, , ,
, . <
-4> .
( , )
( , )
( ) ( , )
( , )
( , )
.
well-being ,
,
.
,
, ,
. ( ) ,
.
.
,
, ,
.
‘ ’ .
2003
2007 10% .
.
: , , 2007.4
40 50 30
20 .
, ,
.
.
.
.
,
, , ,
2~3 .
, TV ,
( ) .
.
,
. ,
.
,
, ,
, , ,
.
, . ,
, .
, / /
.
.
< -6>
II PROTEIN CHIP Section 02
020
.
( ) ,
,
.
.
,
.
.
2000 10%
, 2007 16%
.
, .
022
.
.
LG ,
NT, BT, IT, ET
.
(42 ), (20 ), LG (68
), (48 ) .
44
.
.
2003
4200 , 2004 4800 , 2005 7800 , 2006 8200 ,
2007 9200 10% ,
.
2008
2009
.
,
.
. 40 50
30 20
,
.
, ,
, , , , ,
.
(4)
.
024
. ,
,
.
.
, , , , ,
, OEM ODM ,
, ,
.
.
, , ,
.
. ,
.
.
,
.
,
.
026
. 2003
. " "
,
. 1974 (WHO, World Health Organization)
,
, (Well-being)
(Health is not merely the absence of disease, but a state
of complete physical, mental and social well-being) .
(B&H:
Beauty & Health)
.
'
( )’ ' ( ) ’
.
, ,
.
.
, .
.
.
,
.
, ,
. ,
, ,
.
,
.
9 ,
7 695 2).
,
2001 2006 6 11
2) 2006
.
FTA
.
7
,
.
,
.
.
.
(1)
panese and Chinese) ,
( ) . Wakan Herb
, Wakan
.
Wakan
.
.
)
.
030
Technology Commercialization Intelligence Report
,
.
Anti- Aging ,
Kao
EGCG
. Kose
.
( ) ‘ ’
.
,
. , , ,
, .
.
)
‘Wakanka’( ) 40 50
Wakanka Star fruit leaf( ), Japanese
angelica root( ) . ‘Precious Turn’ 10 20
Wakan [Perilla( )],
, [Citrus junos( ), Fennel( ), Honeysuckle flower
( )], [ Coix seed , Peach leaf ( ]
.
2)
3)
Coix seed( , Ginseng root( ), Licorice root ), Honey-
suckle flower , Japanese angelica root ), Chinese
caterpillar fungus ), Mugwort leaf , Mallow ),
Sweet flag root( , Citrus junos , Nettle leaf
, Perilla leaf , Peach leaf( . ‘Junkisei(
Technology Commercialization Intelligence Report
)’ 20 Wakan Nettle leaf(
), Soybean ,Quince( , Royal jelly, Spring water
.
root ( ), Peony root ( ), Scutellaria root ( ),
Honeysuckle flower ( ) .
5)
‘SINOADORE’ 20 30 Wakan
Japanese angelica root( , Coix seed( ), Honeysuckle
flower( ), Pearl protein( ), Peony root( ),
Sophora root( ) . ‘AYURA’
Wakan Lotus seed( ), Peach seed( ),
Peony root ( ), Hypericam( ) . ‘SOKA MOKKA’
20 30 Wakan Citrus junos( ),
Green Tea( ), Houttuynia( ), .
6)
034
. ,
.
2005 ( ), ( )
(Sephora)
.
(L’Oreal)
Garnier Nutritionist .
Horphag Research Ltd.
Pycnogenol ,
. Milk Thistle
.
.
.
. , , , , ,
.
1973
‘ ' . ( )
( ) ( )
, 1980
' ' . , (
) ( )
1997 ' '( )
.
( ) ( )
7 6 , 11 ,
1 2 , 2 3 .
.
.
036
: ,
( )
1)
40 1967 '
' , 1972
, 1973
(1997 )
LG
(2001 )
(2006 )
, , , ,
, , ,
Technology Commercialization Intelligence Report
, ‘ ’ . 1975
, 1981 , 1987
( )
. 1987 ( ) (
) , 1997
. 2001
, 2002
. 2006
' ’
. 2004~2008 DNA
DNA (Bioin-
formatics)
‘2008 ’
.
’ ,
. ,
, ,
. ( )
,
, , ( ) ,
038
3)
,
.
.
2008
.
,
. , ,
, ,
, ,
GAP(Good Agricultural Practices- )
. ,
,
.
1)
' ,
.
,
.
.
.
,
.
1973
040
Technology Commercialization Intelligence Report
. , , , , , , , ,
, , , , , , , , ,
, , , , ,
,
, .
.
( ), ,
, , 5 . LG
, EL-1
, , , , ,
,
.
, , ,
, , ,
, ,
,
C, , ,
, , ,
, ,
- ,
, ,
, ,
, ,
,
,
, ,
,
, , ,
, ,
, , ,
, , ,
, , ,
, ,
C, , , ,
, ,
,
, ,
, , ,
, ,
A , ,
, , ,
B ,
, B ,
, ,
,
,
, ,
,
,
, , ,
,
, ,
,
,
, D , ,
,
, ,
,
, , ,
, , , ,
,
, , , , ,
042
1)
30
( ) ,
( ) .
, , , , 5
.
, , , ,
5 .
.
3)
( ), ( ), ( ), 5
, ,
.
.
. ( ) ,
, , , , . ( )
( ) 12
7
.
. ( ) 14
.
6)
35
( ) ( )
044
, .
( ) , , , ,
5 .
.
( )
3 ( , , ) ( )
, , ( ) , , , ( )
, , 7
.
8)
( ) ( ) .
, ,
.
( ) , , , , , ,
3
.
3 ( ) , ,
, , , , ,
, , , 9 .
10)
. 30
, , 3 .
11)
.
.
,
046
12)
.
110 ,
, .
13)
14)
. ( ) ,
, ,
. ( )
( )- , ( )- , ( )- , ( )- , ( )-
.
(10 ), ( ), (
) 10 ,
, , , .
( ) ,
‘ ’
.
.
LG ‘ ’
, , ,
, ,
.
‘ ’ 2005 2
. MLPS
, DDS (Drug Delivery System) .
048
, NAG
( ) ,
1) ,
2003 3 21
“ ”
.
.
.
, ,
.
,
( )
(
) .
,
, (
,
) .
, (
, ,
, ,
) .
,
.
,
050
Technology Commercialization Intelligence Report
, NT, BT , , IT
.
,
.
(< -5>) ,
NT,
BT .
-5
,
, , ,
,
,
. ,
, ,
, .
, , , , 5
, ,
.
< -6>
( )
,
.
.
.
NT, BT, IT, ET
.
( )
.
.
M M M M M
H M L
H H H M
L L L M
M M M H M
M M M
Target Ipsa
2004
: ( , n=20), (H: High, M: Medium, L: Low)
( )
,
,
(Confocal, OCT, Raman Spectroscopy )
.
.
054
M L H H H H H
(HUT) L M M H H M L
M M H L M M H
: , ,
2004
: ( , n=20), (H: High, M: Medium, L: Low)
< -9>
: , ,
2004
( )
,
Technology Commercialization Intelligence Report
, ,
.
M H L H H L
M H L L H L
H L L H L H
: , ,
2004
: ( , n=20), (H: High, M: Medium, L: Low)
, ,
(< -1>).
< -1>
: ( ), R&D , 2007
056
, , .
< -2>
. , 1980
1995 2000
.
.
< -3>
1 1 1 1 1 2 2 3 4 5 5
1
, 83
(31%) , 59 (19%), 105 (40%),
26 (10%) .
.
EP, 10%
JP, 19%
KR, 31%
US, 40%
Dow Corning Ltd. 8 , Council of Scientific & Industrial
6 , Rohm and Haas Company 6 , ( ) 6
, Elan Phapma 5 4
.
( ), , LG ( ), ,
( ) .
,
, ,
, ,
.
< -5>
8
6
6
6
5
5
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
0 1 2 3 4 5 6 7 8 9
Do w Co r n i n g
Co u n c i l o f S c i e n t i f i c & I n d u s t r i a l
R e s e a r c h
R o h m a n d Ha a s Co mp a n y
E L AN P HA R MA
NOE V I R CO L T D
S HI S E I DO CO L T D
Ap p t e c I n c .
Os mo t i c a Co r p
GE R VAS I O C AR L A
S t r a t h a u s e n , Ge r o l d
K I S T
Amb r o s P h a r ma S . R . L .
S UNT OR Y L T D
DA V I S B R E NT W
T a k a s a g o I n t e r n a t i o n a l
13 16
8 3) .
060
5 .
, ,
.
,
. ,
.
,
, 10 ,
.
.
.
3) Phrma, 2005
. ,
.
.
(2)
,
.
10% .
, . ,
.
520
,
3 1 .
062
, ,
,
(< -11>).
NT, BT, IT, ET
.
III
,
,
,
.
Euromonitor International , 2005
2,576 , 2008 2,861
. 5% 13 4
.
,
.
2005 2006 2007 2008
( ) 2,576 2,697 2,777 2,861
( ) 12 9000 13 4000 13 8000 14 3000
: Euromonitor International , 2007
: 1. 2008
3%
5%
.
,
2002 3 8 , 2003 4 2 , 2004 4 8 , 2005
7 8 , 2006 8 2 , 2007 9 2
11.2% , 2008 1 1
.
( : )
4,200 4,800 7,800 8,200 9,200 1 1000
: / , 2007
: 2008 2003 2007 19%
, < -1>.
‘ ’ LG ‘ ’ ‘
’, ‘ ’ .
5
, LG 1
.
. ,
, ,
.
.
.
.
068
.
.
, ,
.
.
/ ,
.
n
. , 2010
.
n
,
.
.
n
, .
,
070
Technology Commercialization Intelligence Report
. 2 3
.
n
50 , 150
.
2003
.
n
.
,
.
(2)
5,000
LG 2003 ` `
. 2003 9 ` `
, 1,000
.
.
50 , , , , , , ,
150 ,
.
.
.4)
,
. Avon
‘Surage( )’ .
‘Sinoadore' ,
,
R&D .
4) , ‘ ’, J of Korean
Cosmetology, 2007. 12
Technology Commercialization Intelligence Report
, , , R&D
.
‘Freeplus’ , 80
‘ ’ .
NaturNorth Technologies
.
‘ ’ ,
‘ ’ .
. ‘Shahnaz Diamond'
,
(Ayuryeda)
.
(2)
,
. 1967
‘ ’ 1972
1973
‘ ’ . 1997
35
,
.
20, 30
‘ ’ .
,
. , , , ,
“ ” , ,
(8 ), , , .
,
.
(20 )
.
.
.
074
2006 4
, . 2011 20
,
.
. 2007 8,000
.
( ) LG
‘
’ . 2003 9
3 1
.
1
.
2005 340 2006 800
, 1
.
. ,
.
,
.
.
20 , .
,
. 3
.
,
.
2 LG
.
.
8 , 2 , 1.5
.
20 30
.
.
076
2003
200 . 2004
22
.
( ,
, , ) 20 .
,
.
< -3>
·
- ,
-
-
LG
, , ) - ,
- - + +
-
-
- ( , )
- - , ,
) -
- ( , , )
- -
- ( ) ( )
- MME
9 -‘ ’
-
- ( ,
, , , )
-NBT
-
- -
, , , , )
-30
- -3
-
- -
-
- ,
- ,
-30 40 - ,
-
-
, , , )
078
. (genomics),
(proteomics)
.
.
.
.
2,697 .
30%, 25%,
24% , , , ,
.
3% 2013
3,316 ,
5% 2013 16 5,000
< -4>
) 1. 2008
3%
2. 5%
.
5 7,400 .
3% 2013 6 8,539
. 2007 9,200 2013
2 3,700 < -5>.
3 4 ,
.
.
,
080
Technology Commercialization Intelligence Report
20 30
.
( : )
) 1. 2008
3%
,
. , 5 25 67%
(< -6>).
< -6> 5
(%)
( )
2009 6000 2011 7500 25%
2010 600 2012 880 47%
2008 300 2010 500 67%
2010 1200 2012 1500 25%
: , , , 2008. 1
PROTEIN CHIP Section 04
.
,
,
.
, ,
, < -1>.
.
< -1>
084
.
.
/
. ,
, , , DB
, .
< -2>
: , , 2007
,
. (
) (
)
.
< -3> ,
, , .
< -3>
086
, ,
, .
,
.
,
.
< -4>
4.
< -5>
.
088
.
.
,
.
,
NT, BT, IT, ET
.
.
.
, .
.
,
,
.
, DB , ,
,
· .
, , , 2006. 6
2. ,
, , , 2005. 12
3. , ,
, , 2004, 12
4. , , J. of
Korean Cosmetology, 2007, 12 , pp. 36 40
5. , “ ”, ,
2003
7. , " ", 2005
8. (2005 , 2006 , 2007 )
9. ( ) , ,
, 2007. 4
11. , , ,
, , , PP. 40 43.
12. ( ) R&D , R&D , 2007. 5.
13. , , , 2007. 6
14. , , , 2008. 10
090
, 2005. 6
, pp. 114 125
, 2005 ,
, 2008. 3
2005. 10
21. , " ", 5 , 2007
22. , “
”, 2004
23. , , 2008. 4
24. R&D , ( ) R&D , 2007. 5
25. , , , 2007
26. , , ,
, 2006. 10
28. http://jangup.com
29. http://www.dailycosmetic.com
30. http://www.cmn.co.kr
31. http://www.beautynury.com
32. http://www.bosa.co.kr