patomekanisme thalasemia
DESCRIPTION
mecanism of thalasemiaTRANSCRIPT
![Page 1: patomekanisme thalasemia](https://reader036.vdocuments.pub/reader036/viewer/2022082417/563db7c0550346aa9a8d9eb1/html5/thumbnails/1.jpg)
Thalasemia β
Gangguan pembentukan gen
globin β
<<rantai β dalam tubuh
Rantai α berlebihan tidak seimbang
Terbentuk molekul abnormal
Sifat tdk stabil, mdh terpresipitasi & gang eritropoiesis
Produksi eritrosit
Hb
ANEMIA
Lemas, pusing
Gangguan pertumbuhan
Gangguan pekembangan
Hematopoiesis extrameduler
Tulang : os.maxilla & zigomaticum
Facies cooley
Hepar dan lien hepatosplenomegali
![Page 2: patomekanisme thalasemia](https://reader036.vdocuments.pub/reader036/viewer/2022082417/563db7c0550346aa9a8d9eb1/html5/thumbnails/2.jpg)