postgraduate quiz instructions all slides carry equal marks there is no negative marking each slide...
TRANSCRIPT
Postgraduate Quiz
Instructions• All slides carry equal marks• There is no negative marking• Each slide will be given 30 seconds to 1 minute
after reading out the question
All the Best!
Q1.
• 18 years female presented with high grade fever• She was a known case of HIV
PBF• Identify the abnormality• Advice Cytochemistry
Q2.
• 48 years ♀ presented with weakness & variable cytopenias• She was being treated for depression
Trephine biopsy• Identify the abnormality• Advice Confirmatory test
Q4.
HPLC graph from BioRad Classic
• Identify the abnormality
• What will be the expected clinical phenotype?
Q6.
64 year male with splenomegaly.• Interpret the flow cytometry• Suggest a molecular confirmatory test for this disease?
Q8.
Describe the morphology of the cell in the peripheral blood film.Mention 2 conditions where this can be seen
Father (Case II)
Son (Case I )
?
Methemoglobin levels:
7.5% & after blood transfusion- 0.3%
OxyHb is capable of reversible oxygenation; its heme iron is in the reduced (or ferrous) stateMetHb: Heme oxidizes spontaneously & is incapable of reversible oxygenation
Q10.
• 21 years ♀ presented with gum bleeds & skin nodule• Blood counts showed increased TLC with thrombocytopenia
BM aspirate1. Suggest possible diagnosis2. Suggest associated
cytogenetic abnormality
Q6.• 2 year male presented with epistaxis• Coagulogram: PT- 13 sec, APTT-27 secs, N platelets
Platelet aggregation
Physiological Agonists ADP 10mMCollagen 2mg/ml Epinephrine 10mM Arachidonic acid 0.5mM
• What is the diagnosis?• What will you find in a finger prick smear• What is the mode of inheritance of the condition?
Q 11.
Kidney biopsy from a 33 yr female with seizures and acute renal failure following fever for a day.
• What is the diagnosis?• What will the PT & PTTK
results?• Mention one therapeutic
modality.
Two siblings ages 3 & 5 years presented with pallor and mild hemolytic faciesBM was done to investigate cause of anemia
Q 12.
BM aspirate
Descibe the BM findingsAny confirmatory tests?
Trephine biopsy
Q 13.
6 months child presented with progressive anemia and splenomegalyScreening for thalassemia was negative
Descibe the findingsAny special stains?
Q 14.• 13 yrs male presented with fever & echymosis for 3 days• Blood cell counts showed anemia, leucocytosis and thrombocytopenia
BM MPO
Describe the BM findings and interpret the MPO stain