ramadology - lens chapter
DESCRIPTION
Ramadology - Lens chapterTRANSCRIPT
Crystalline lens
Crystalline lens
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� Anatomy ��
� Cataract �����
- Congenital
- Senile
- Complicated
- Traumatic
� Ectopia Lentis �
- Subluxation
- Dislocation
Crystalline lens
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
CCCCrystalline LenSSSS
Suspensory zonules = Zonules of Zinn = Ciliary zonulesSuspensory zonules = Zonules of Zinn = Ciliary zonulesSuspensory zonules = Zonules of Zinn = Ciliary zonulesSuspensory zonules = Zonules of Zinn = Ciliary zonules
5 mm 10 mm
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
---- Avascular, biconvex, elastic, transparent structure.
Suspended in its place by the suspensory ligament ( Zonule( Zonule( Zonule( Zonulessss of of of of ZZZZinn )inn )inn )inn ). -
Gross Anatomy
ite:SSSS1.
- AnteriorAnteriorAnteriorAnterior to it : Iris ( separated by posterior chamber )
- PosteriorPosteriorPosteriorPosterior to it : Vitreous ( separated by RetroRetroRetroRetro----lental spacelental spacelental spacelental space ) �
hape:SSSS2.
- Anterior Anterior Anterior Anterior surfacesurfacesurfacesurface: LESS convex than posterior [ its centre is : Anterior pole ] �
- Posterior Posterior Posterior Posterior surfacesurfacesurfacesurface: MORE convex [ its centre is : posterior pole ] �
- Axis = Axis = Axis = Axis = ThicknessThicknessThicknessThickness: Line joins the anterior & posterior poles ( 5555 mm ).
---- Equator = lens Equator = lens Equator = lens Equator = lens edgeedgeedgeedge: Gives attachment to the suspensory ligament ( 10101010 mm ).
onsistency:CCCC3.
- YoungYoungYoungYoung: Soft
- OldOldOldOld : Hard
olor:CCCC4.
- ChildrenChildrenChildrenChildren: Colorless�
- AdultAdultAdultAdult : Yellowish tinge
- OldOldOldOld : Grayish
�� ) 1.4= (Average ndex:i efractiveefractiveefractiveefractiveRRRR5.
- CortexCortexCortexCortex: 1.38
- NucleusNucleusNucleusNucleus: 1.42
The ability of lens to converge parallel rays. :powerpowerpowerpowerefractive efractive efractive efractive RRRR6.
- Inside the eye : +18 DDDD (Un-accommodated)
- Outside the eye: + 70 DDDD due to :
1) � Curvature (Becomes spherical)
2) � Refractive index
So, the Cornea is the Main refractive So, the Cornea is the Main refractive So, the Cornea is the Main refractive So, the Cornea is the Main refractive mediamediamediamedia in the eye.in the eye.in the eye.in the eye. ����
P O W
1 1 3 Anatomy
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Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
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Minute anatomyMinute anatomyMinute anatomyMinute anatomy
SutureSutureSutureSutures in Lenss in Lenss in Lenss in Lens
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Minute Anatomy
1. 1. 1. 1. CCCCapsuleapsuleapsuleapsule::::
Character Significance
capsular epithelium.-anterior subby SecretedSecretedSecretedSecreted
membrane. Elastichighly Accommodation
Semi-permeable membrane - Diffusion of nutrients in & waste products out
- Protection: Of lens fibers from aqueous enzymes
anterior capsule > posterior. Thickness:Thickness:Thickness:Thickness: ……………….……………….……………….……………….……………….……………….
ubcapsular epitheliumubcapsular epitheliumubcapsular epitheliumubcapsular epitheliumSSSS2. 2. 2. 2.
- SSSSite: Lines the capsule ( anteriorly & at equator ) NOTNOTNOTNOT posterior. �
- SSSShape: Cuboid , columnar & pyramidal.
♣♣♣♣ Function :Function :Function :Function :
1. AAAAnterior cells: secrete capsule.
2. PPPPosterior sub-capsular : in 3333rdrdrdrd
month of pregnancy form embryonic nucleus. �
3. PPPPyramidal ( Equatorial ) cells : differentiate into lens fibers.
ibers of lens:ibers of lens:ibers of lens:ibers of lens:FFFF3. 3. 3. 3.
- DifferentiateDifferentiateDifferentiateDifferentiate from: Equatorial cells.
---- DividedDividedDividedDivided into:
1) Peripheral fibers: Sost ( corFex ).
2) CentGal fibers : Hard ( nucleus ) d.t. compression & sclerosis ( loss of water )
---- SuturesSuturesSuturesSutures: Site of articulation of lens fibers (In FetalFetalFetalFetal nucleus � erect Yerect Yerect Yerect Y----shapshapshapshaped anteriorly ed anteriorly ed anteriorly ed anteriorly & Inverted Y posteriorly Inverted Y posteriorly Inverted Y posteriorly Inverted Y posteriorly ) �
into:is divided NucleusNucleusNucleusNucleusIf a section in eye is done by slit lam, the N.B.N.B.N.B.N.B. ��������
1) EmbryonicEmbryonicEmbryonicEmbryonic nucleus: 1-3 months intGauterine.
2) FetalFetalFetalFetal nucleus: From 3rd
month till birth
3) InfantileInfantileInfantileInfantile nucleus: up to puberty.
4) Adult Adult Adult Adult nucleus: After puberty.
ciliary zonules ciliary zonules ciliary zonules ciliary zonules = = = = inn inn inn inn ZZZZof of of of sssszonulezonulezonulezonule= = = = N.B.: Suspensory ligaments of lens N.B.: Suspensory ligaments of lens N.B.: Suspensory ligaments of lens N.B.: Suspensory ligaments of lens ��������
---- Extend Extend Extend Extend from:from:from:from: ciliary body to the edge ( equator ) of lens.
---- Secreted Secreted Secreted Secreted by:by:by:by: ciliary body epithelium.
---- Function:Function:Function:Function: Accommodation.
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Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Mechanism of
Contraction of ciliary muscle �
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Hyaloid arteryHyaloid arteryHyaloid arteryHyaloid artery
AccommodationMechanism of
� relaxation of zonules � � lens curvature �
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
� � power of lens
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
1) Water : 65%
2) Proteins : 34% [ Highest protein content of any other tissue in the body
3) Minerals : 1%
1) Before Before Before Before birthbirthbirthbirth: Hyaloid artery.
2) After After After After birthbirthbirthbirth: diffusion from aqueous (through
- AnaerobicAnaerobicAnaerobicAnaerobic ( as the lens is avascular = NO
carriers as vitamin C & Glutathione.
1) RefractiRefractiRefractiRefractionononon of light.
2) AccommodationAccommodationAccommodationAccommodation: The ability of the eye to change its power to see
distances ]
3) Protection of the Protection of the Protection of the Protection of the retinaretinaretinaretina by absorbing the U.V. rays.
If remnantremnantremnantremnant of hyaloid artery is present after birth, it will leave opacity at the posterior pole of lens
Deficiency of vitamin C & Glutathione
Cataract cause
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Composition
Highest protein content of any other tissue in the body ] �
Blood supply
" AvascularAvascularAvascularAvascular """"
(through the semisemisemisemi----permeablepermeablepermeablepermeable membrane of capsule)
Metabolism
NO enough O2 ). Oxidation occurs by dehydrogenation which requires hydrogen
Nerve supply
NONONONO nerve supply
Lymph supply
NONONONO lymph supply
Function of lens
The ability of the eye to change its power to see clearly at different distances [ far or near
absorbing the U.V. rays.
of hyaloid artery is present after birth, it will leave opacity at the posterior pole of lens
� Posterior polar cataract Posterior polar cataract Posterior polar cataract Posterior polar cataract
Deficiency of vitamin C & Glutathione � Disturbed metabolism � Opacity of lens (Cataract)
of vision � PAINLESSCataract cause
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
). Oxidation occurs by dehydrogenation which requires hydrogen
different distances [ far or near
of hyaloid artery is present after birth, it will leave opacity at the posterior pole of lens
Opacity of lens (Cataract)
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
of the lens. opacityopacityopacityopacityIt is the : DefinitionDefinitionDefinitionDefinition
Classifications :Classifications :Classifications :Classifications :
A. According to the cause:A. According to the cause:A. According to the cause:A. According to the cause:
1) Congenital
2) Acquired [Traumatic, Complicated or Senile]
B. According to the site:B. According to the site:B. According to the site:B. According to the site:
1) Capsular: anterior or posterior
2) CorFical: anterior or posterior
3) Nuclear
4) CorFico-nuclear
C. According to the age:C. According to the age:C. According to the age:C. According to the age:
1) Soft CataractSoft CataractSoft CataractSoft Cataract: before 25252525 years.
CauseCauseCauseCause: Congenital, Traumatic or Complicated.
nucleus. Soft: NucleusNucleusNucleusNucleus
crystalline crystalline crystalline crystalline mainly Lens protein:Lens protein:Lens protein:Lens protein:
TTTTTTTTTTTT: as in congenital cataract.
2) Hard cataractHard cataractHard cataractHard cataract: above 25252525 years
CauseCauseCauseCause: Senile, Traumatic or Complicated.
nucleus. hard: NucleusNucleusNucleusNucleus
albuminoid protein (albuminoid protein (albuminoid protein (albuminoid protein (: mainly Lens proteinLens proteinLens proteinLens protein
enzymes.
TTTTTTTTTTTT: as in senile cataract.
After cataractAfter cataractAfter cataractAfter cataract
NONONONO
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of the lens.
2) Acquired [Traumatic, Complicated or Senile]
: Congenital, Traumatic or Complicated.
which can be digested by aqueous enzymes. ))))protein solublesolublesolublesolubleprotein (protein (protein (protein (crystalline crystalline crystalline crystalline
: as in congenital cataract.
: Senile, Traumatic or Complicated.
be digested by aqueous NOTNOTNOTNOTwhich can ))))protein insolubleinsolubleinsolubleinsolublealbuminoid protein (albuminoid protein (albuminoid protein (albuminoid protein (
Cataractالميّه البيضا
After cataractAfter cataractAfter cataractAfter cataract, if some lens particles are left
after cataract, if some lens particles are left
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
which can be digested by aqueous enzymes.
be digested by aqueous
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Definition Definition Definition Definition
BilateralBilateralBilateralBilateral, Gradually progressiveGradually progressiveGradually progressiveGradually progressive lens opacity, affecting oldoldoldold age, NOTNOTNOTNOT d.t. trauma, local or general disease. ��
Incidence:Incidence:Incidence:Incidence:
• AgeAgeAgeAge: > 50 years
• SexSexSexSex: ♀ = ♂
• HereditaryHereditaryHereditaryHereditary: may play role
[Cataract tends to appear at an earlier ageearlier ageearlier ageearlier age in successive generations (anticipation ) (anticipation ) (anticipation ) (anticipation ) ]
• SideSideSideSide : Bilateral (One eye precedes the other eye) ����
Etiology:Etiology:Etiology:Etiology:
Types: Types: Types: Types:
1) CorFical 75%1) CorFical 75%1) CorFical 75%1) CorFical 75% 2) Nuclear 20%2) Nuclear 20%2) Nuclear 20%2) Nuclear 20% 3) CorFico3) CorFico3) CorFico3) CorFico----nuclear 5%nuclear 5%nuclear 5%nuclear 5%
P O W
5 5 5
Senile Cataract
������������ Metabolic disturbancesMetabolic disturbancesMetabolic disturbancesMetabolic disturbances �
� Change in Lens proteins:proteins:proteins:proteins: Coagulation
� Change in WaterWaterWaterWater content: Hydration.
The metabolic disturbances may occur due to :
permeability. capsule1) DistLrbed
break down �activate dormant enzymes ( α & β proteases ) �: d.t. accumulation of lactic acid pH2) DistLrbed
of lens protein � opacity.
.vitamin C & glutathione3) Deficiency in
disturbances. Endocrinal4)
.U.V. rays5)
6) � Fat content & insoluble protein with � in soluble protein.
7) � Na, Ca , � K.
75
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Slit lamp ( BioSlit lamp ( BioSlit lamp ( BioSlit lamp ( Bio----microscopy )microscopy )microscopy )microscopy )
Direct ophthalmoscopeDirect ophthalmoscopeDirect ophthalmoscopeDirect ophthalmoscope
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Method of examination of lens Method of examination of lens Method of examination of lens Method of examination of lens
By TorchTorchTorchTorch OrOrOrOr Slit lampSlit lampSlit lampSlit lamp (gives more details with powerful illumination & magnification).
To examine:
1) LensLensLensLens Capsule
2) LensLensLensLens Opacity
3) Anterior chamber depth
4) IrisIrisIrisIris
5) IrisIrisIrisIris shadow
In dark room to dilate pupil [Red Reflex �
� Clear areas: appears Red.
� Opacity: appears Dark.
�: To know if there is Tonometry
[Glaucoma should be tGeated 1should be tGeated 1should be tGeated 1should be tGeated 1
� Def. The shadow of iris on the lens opacity.
� Shape: Black Crescent in the pupil.
Oblique Illumination is directed to eye at 45 to see shadow : How �
lear C When to see shadow : �
� It is present in:
( Immature cataract
[Iris shadow becomes smaller while
Hypermature cataract �
Oblique illumination
Red Reflex is a more reliable
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ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Method of examination of lens Method of examination of lens Method of examination of lens Method of examination of lens
Oblique illumination
details with powerful illumination & magnification).
3) Anterior chamber depth
]In dark room to dilate pupil
lytic glaucoma-morphic glaucoma & phaco-e.g. Phaco in I.O.P. �
should be tGeated 1should be tGeated 1should be tGeated 1should be tGeated 1stststst for fear of optic nerve atrophy ]
���Iris Shadow��
�
The shadow of iris on the lens opacity.
in the pupil.
°Oblique Illumination is directed to eye at 45
.Opacitybetween iris & the intervallear
is occupied by clear lens fibers ) interval(
[Iris shadow becomes smaller while the cataract is going to maturity]
i.e. NO Iris shadow in Mature cataract
is occupied by aqueous ) interval( Hypermature cataract
blique illumination �Red Reflex
more reliable method in estimation the maturity of cataract than iris
shadow.�
76
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
lytic glaucoma
atrophy ]
.°
is occupied by clear lens fibers )
the cataract is going to maturity]
ed Reflex Tonometry
method in estimation the maturity of cataract than iris
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Types of senile cataract :Table
Nuclear Hypermature Mature Intumescent Immature
6/9 �H.M H.M H.M C.F or H.M 6/9 � C.F. Symptoms
Visual acuity
Central lens
opacity
Shrunken +
deposits Totally Opaque
Sectors + Swollen
+ water vacuoles.
Grayish sectors
at periphery
Signs Lens
N. Thickened N. Glistening N. Lens
capsule
N. Deep N. Shallow N. A.C. depth
N. Tremulous N. Pushed anteriorly N. Iris
Present May be Absent May be Present Iris shadow
Dark central
disc against a
reddish
background
(Black reflex in
cataracta nigra)
Absent Absent Partially seen
Black triangular
sectors against a
reddish
background
Red Reflex
N. may � N. may � N. Tension
of visionof visionof visionof vision ���� lesslesslesslessD.D. of gradual painD.D. of gradual painD.D. of gradual painD.D. of gradual pain - Open angle glaucoma. - Senile cataract - Age related macular degeneration ( ARMD ). - Progressive (malignant) myopia. - Diabetic retinopathy. - Optic neuropathy / atrophy
Senile cataractSenile cataractSenile cataractSenile cataract A.RA.RA.RA.R.M.D.M.D.M.D.M.D OOOOpen angle glaucomapen angle glaucomapen angle glaucomapen angle glaucoma OOOOptic atrophyptic atrophyptic atrophyptic atrophy
LensLensLensLens Greyish white N. N N
Red ReflexRed ReflexRed ReflexRed Reflex Affected N. N. N.
Light ReflexLight ReflexLight ReflexLight Reflex Present Present Present � down to loss
IOPIOPIOPIOP N. N. � N
FundFundFundFunduuuus s s s N. Macular degeneration Optic cupping Optic atrophy
FieldFieldFieldField N. Central scotoma Central & peripheral
defect Complete field defect
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Senile Nuclear cataract Senile Cortical cataract
Pathological lens sclerosislens sclerosislens sclerosislens sclerosis � Nuclear opacification Cortical opacification DefinitionDefinitionDefinitionDefinition
� Progression is very slow.very slow.very slow.very slow.
� NO stages NO stages NO stages NO stages i.e NONONONO intumescent, NONONONO hypermature.
� The lens acquires a colourcolourcolourcolour
(due to Urochrome pigment)
� Opacity is affecting the cortexcortexcortexcortex
[ PeripheryPeripheryPeripheryPeriphery of lens at first thenthenthenthen become total ]total ]total ]total ]
� Last fibersLast fibersLast fibersLast fibers to be opaque are the subcapsular fiberssubcapsular fiberssubcapsular fiberssubcapsular fibers.
� Most common tSTe of senile cataract ( 75% ). ��������
CharacterCharacterCharacterCharacter
No stages �
GradesGradesGradesGrades Grade I : GGGGrey
Grade II : YYYYellow
Grade III : Light BBBBrown
Grade IV : BBBBrown (cataracta brunescens) �
or
BBBBlack (Cataracta nigra) �
Immature
( Lens is NOTNOTNOTNOT totally opaque )
with its base Opacity begins as triangular streaksOpacity begins as triangular streaksOpacity begins as triangular streaksOpacity begins as triangular streaks
directed towards the equator.
�Mature
(lens is Totally Totally Totally Totally Opaque) Hypermature
Degeneration & liquefaction of lens matter �
loss of water � shrinkage
Stages: Stages: Stages: Stages:
Nuclear [ Immature stage ] SymptomSymptomSymptomSymptomssss
d.t. opacity & of vision of vision of vision of vision � lesslesslesslessGradual painGradual painGradual painGradual pain �
( increased R.I ). myopiaindex
Fixed muscaFixed muscaFixed muscaFixed musca d.t. opacity.
� UniUniUniUni----ocular diplopia ocular diplopia ocular diplopia ocular diplopia d.t. sectorial change in
refractive index.
� Gradual painGradual painGradual painGradual painlesslesslessless � of vision (Uom 6/6 of vision (Uom 6/6 of vision (Uom 6/6 of vision (Uom 6/6 ����
C.F) C.F) C.F) C.F) d.t. opacity & index hypermetropia
Fixed muscaFixed muscaFixed muscaFixed musca d.t. opacity.
� UniUniUniUni----ocular diplopia ocular diplopia ocular diplopia ocular diplopia d.t. sectorial change in
refractive index.
� Day BlindnessDay BlindnessDay BlindnessDay Blindness (as there is miosis during the
day)�
� 2222ndndndnd
sightsightsightsight� : sclerosis �����RI ����� lens power
���� index myopia �
SOSOSOSO, a presbyopic patient Can read again without his
reading glasses.
� Night blindnessNight blindnessNight blindnessNight blindness as the peripheral opacity
interfere with the entry of light to peripheral
retina (where rods present) �
� Glare & colored halosGlare & colored halosGlare & colored halosGlare & colored halos around light.
See Table SignsSignsSignsSigns
Types of senile cataract ………….
� Causes of gradual painless � of vision………....
Senile nuclear sclerosis…………..
Types of senile cataract ………….
� Causes of gradual painless � of vision………....
Complicated Cataract …..……
D.D.D.D.D.D.D.D.
77
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
�
DefDefDefDef.... It is a physiologicalphysiologicalphysiologicalphysiological nucleus sclerosis (loss of water)
C/P: C/P: C/P: C/P:
�Symptoms:Symptoms:Symptoms:Symptoms: VisionVisionVisionVision is NOTNOTNOTNOT affected!
�Signs: Signs: Signs: Signs:
���� Oblique illumination:Oblique illumination:Oblique illumination:Oblique illumination: Grayish pupil
���� Red Reflex:Red Reflex:Red Reflex:Red Reflex: Normal (as lens is transparent)
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Immature cataract
Mature cataract
Hypermature cataract
Senile nuclear sclerosis �
sclerosis (loss of water)
affected! (as lens is transparent )
Grayish pupil ( d.t. � R.I of lens)
(as lens is transparent)
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
N.B. Hypermature cataract
The nucleus sinksnucleus sinksnucleus sinksnucleus sinks by gravity to the lower portion of lens [ The Upper edge of nucleus may be seen when the pupil is
dilated ] as the degenerated lens matter becomes liquefied into a milky fluid.
Complications of hypermature cataract
is irritant ) (whichof lens protein DegenerationDegenerationDegenerationDegeneration1) 1) 1) 1)
lens displacement (subluxation or dislocation) � of zonules DegenerationDegenerationDegenerationDegeneration 2)2)2)2)
Intumescent Cataract (Swelling) N.B. ���� Mechanism: Mechanism: Mechanism: Mechanism: Rapid break down of lens protein
PhacoPhacoPhacoPhaco [[[[ predisposed eyein �may IOP : IOP : IOP : IOP : ����
���� Treatment :Treatment :Treatment :Treatment : Do laser iridotomy before cataract operation .
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
N.B. Hypermature cataract
2 types
TypicalTypicalTypicalTypical �
(Discussed B4)
�typetypetypetype MorgagnianMorgagnianMorgagnianMorgagnian
by gravity to the lower portion of lens [ The Upper edge of nucleus may be seen when the pupil is
dilated ] as the degenerated lens matter becomes liquefied into a milky fluid. [[[[ Lens does NOT Lens does NOT Lens does NOT Lens does NOT
Complications of hypermature cataract�toxic uveitis-Phacoi) � is irritant )
ii) Phaco-lytic glaucoma�
lens displacement (subluxation or dislocation)
Intumescent Cataract (Swelling)
Rapid break down of lens protein � Rapid � in osmolarity of lens � Rapid hydrationRapid hydrationRapid hydrationRapid hydration
as the iris is pushed by lens � ]]]]morphic glaucoma morphic glaucoma morphic glaucoma morphic glaucoma ----PhacoPhacoPhacoPhaco
Do laser iridotomy before cataract operation .
78
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
by gravity to the lower portion of lens [ The Upper edge of nucleus may be seen when the pupil is
Lens does NOT Lens does NOT Lens does NOT Lens does NOT shrink ]shrink ]shrink ]shrink ]
Complications of hypermature cataract
Intumescent Cataract (Swelling)
Rapid hydrationRapid hydrationRapid hydrationRapid hydration of lens.
Closure of angle �as the iris is pushed by lens
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
work !work !work !work !Unable to do his Unable to do his Unable to do his Unable to do his
NONONONO Medical TTT of cataract till NOW [Everyone has his own needs]
Types of IOL
:site1. According to the
A.C. IOL
i) Angle fixed
ii) Iris fixed
� P.C. IOL:
The best correction of aphakia because it is the nearest to nodal point.
i) In the bag
ii) Sulcus fixed
iii) Iris sutured
:material2. According to the
Hard : PMMA ( poly methyl meth-acrylate )
� Soft ( foldable ) : made from silicon or acrylic.
Accommodative
:II K formulaRS ⌧
P = A - 0.9 K - 2.5 L
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Treatment of senile cataractTreatment of senile cataractTreatment of senile cataractTreatment of senile cataract
������������ The Treatment is The Treatment is The Treatment is The Treatment is ONLYONLYONLYONLY Surgical Surgical Surgical Surgical (lens(lens(lens(lens extraction)extraction)extraction)extraction) ������������
� Cataract extractionCataract extractionCataract extractionCataract extraction Correction of aphakiaCorrection of aphakiaCorrection of aphakiaCorrection of aphakia
Time of operation ?Time of operation ?Time of operation ?Time of operation ?
When the patient is unable to do his work irrespective
to the stage, depending on patient's requirement.
���� Type of operation ?Type of operation ?Type of operation ?Type of operation ?
- Intra-capsular cataract Extraction (ICCE) ………..
- Extra-capsular cataract Extraction (ECCE) ………..
- Phaco-emulsification ………..
Which eye 1Which eye 1Which eye 1Which eye 1stststst ????
The more advanced stagemore advanced stagemore advanced stagemore advanced stage (Except (Except (Except (Except in intumescent
cataract which is tGeated 1st for fear of glaucoma))))
��
N.B. N.B. N.B. N.B. We NEVER operate on the 2 eyes in the same siYing We NEVER operate on the 2 eyes in the same siYing We NEVER operate on the 2 eyes in the same siYing We NEVER operate on the 2 eyes in the same siYing
for the fear of bilateral complication as
endophthalmitis d.t. hidden septic focus.
N.B. N.B. N.B. N.B. Least intervalLeast intervalLeast intervalLeast interval betZeen the 2 operations is 7 days.7 days.7 days.7 days.
� Special consideration Special consideration Special consideration Special consideration beforebeforebeforebefore operationoperationoperationoperation
1. General examination1. General examination1. General examination1. General examination
- General medical check up to ensure surgery fitness.
- Control of any systemic disease especially D.M. &
hypertension.
�� Uncontrolled hypertensionUncontrolled hypertensionUncontrolled hypertensionUncontrolled hypertension � expulsive
hemorrhage.
�� Uncontrolled D.MUncontrolled D.MUncontrolled D.MUncontrolled D.M �
� Possibility of infection.
Possibility of Hemorrhage
(during or after the operation)
� Delayed wound healing.
- Exclude presence of any septic focus in the body
( e.g. Tonsilitis, nasal sinusitis, dental, renal ..) for the
fear of endophthalmitis.
- Exclude & treat any cause of straining e.g. chronic
cough, enlarged prostate & constipation
to avoid � IOP � post operative hyphema, iris
prolapse & delayed reformation of A.C.
2. Local examination2. Local examination2. Local examination2. Local examination
- Complete ophthalmic examinationexaminationexaminationexamination to exclude other
ocular pathology.
- Treat Treat Treat Treat any local disease 1st e.g. chalazion, stye &
rubbing lash
- Exclude presence of any septic focusseptic focusseptic focusseptic focus in the eye,
especially chronic dacryocystitis. �
- If glaucomaIf glaucomaIf glaucomaIf glaucoma, tGeat it 1st. �
- Be sure that the visual acuityvisual acuityvisual acuityvisual acuity of the patient
corresponds to the cataract density.
- Test posterior segment & macular functionTest posterior segment & macular functionTest posterior segment & macular functionTest posterior segment & macular function in presence
of dense cataract.
3. Calculate the power of I.O.L which will be 3. Calculate the power of I.O.L which will be 3. Calculate the power of I.O.L which will be 3. Calculate the power of I.O.L which will be
implantedimplantedimplantedimplanted
Measure the AxiaL lensAxiaL lensAxiaL lensAxiaL lens of the eye
(using AAAA scan Ultrasound ) [Biometry][Biometry][Biometry][Biometry]
� Measure the power of corneapower of corneapower of corneapower of cornea
(using Keratometry )
Then we put & � in a formula to calculate the
power of IOL needed to be implanted.
79
E.C.C.E
EEEE....CCCC....CCCC....EEEE
PhacoPhacoPhacoPhaco----emulsificationemulsificationemulsificationemulsification
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
LLLLTypes of Operation ?Types of Operation ?Types of Operation ?Types of Operation ? LLLL
ICCEICCEICCEICCE ECCEECCEECCEECCE
Principle
Complete removal of lens within its capsule
after cutting the zonules.
Removal of anterior capsule (Anterior
capsulotomy ) leaving the posterior capsule
intact.
� Delivery of nucleus
Washing the remaining lens matter by
irrigation aspiration.
� Implantation of P.C. IOL.
Indication
Rarely done exceptexceptexceptexcept in :
Hypermature cataract with sublaxation of
lens.
SurgerySurgerySurgerySurgery ofofofof choicechoicechoicechoice, unless it is contraindicated
with markedly sublaxated or dislocated lens.
Disadvantage
- VerS large incision (Uom 3 to 9 O'clock )
- High incidence of vitreous prolapse.
- Inability to implant P.C. IOL, SoSoSoSo the eye is
left aphakic !!
)))) PhacoPhacoPhacoPhaco----emulsificationemulsificationemulsificationemulsification))))
�������� [ The most widely technique used nowadays ] [ The most widely technique used nowadays ] [ The most widely technique used nowadays ] [ The most widely technique used nowadays ] ��������
Small incision < 3mm ����
� Removal of anterior capsule
Emulsification of nucleus by introducing a probe having ultrasonic power.
� Irrigation & aspiration.
� Implantation of folded IOL ( by special forceps or injector ) inside capsular bag & it will be unfolded there.
AdvantageAdvantageAdvantageAdvantage
Small incision�
� Rapid visual recovery�
Rapid return to daily activity�
� Less astigmatism�
80
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Down syndromeDown syndromeDown syndromeDown syndrome
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Snowflake cataractSnowflake cataractSnowflake cataractSnowflake cataract
GalactosaemiaGalactosaemiaGalactosaemiaGalactosaemia
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Complicated CataractComplicated CataractComplicated CataractComplicated Cataract
Definition:Definition:Definition:Definition: Lens opacificationLens opacificationLens opacificationLens opacification d.t. local eye disease or a general disease.
Etiology:Etiology:Etiology:Etiology:
Local causes:Local causes:Local causes:Local causes:
1) CorneaCorneaCorneaCornea: : : : e.g. keratitis
2) AAAA.C..C..C..C.: e.g. glaucoma.
3) Uveal tractUveal tractUveal tractUveal tract: e.g. chronic iridocyclitis.
4) LensLensLensLens: e.g. subluxation and dislocation
5) RetinaRetinaRetinaRetina: e.g.
� Retinal detachment. � Retinitis pigmentosa � Chorio-retinitis
6) OtherOtherOtherOther causes: as
� High myopia� � Intra-ocular tumors � Topical drugs: as prolonged use of steroids
� Local irradiation & exposure to infra red rays [[[[ Glass blower cataractGlass blower cataractGlass blower cataractGlass blower cataract ]]]] �
���� General:General:General:General:
� Diseasesiseasesiseasesiseases: as
� Diabetes Mellitusiabetes Mellitusiabetes Mellitusiabetes Mellitus ���� 2 types of cataract may occur
i. Snowflake cataract: occur in juvenile uncontrolled D.M. [[[[ True Diabetic CataractTrue Diabetic CataractTrue Diabetic CataractTrue Diabetic Cataract ]]]] �
ii. Pre-senile cataract: as senile cataract but occurs earlierearlierearlierearlier < 45yG & matures rapidly.matures rapidly.matures rapidly.matures rapidly. �
Down syndrome
� HypOparathyroidismparathyroidismparathyroidismparathyroidism: tetany appear 1st then cataract develops. �
� HypOcalcaemiacalcaemiacalcaemiacalcaemia
� HypOthyroidism.thyroidism.thyroidism.thyroidism.
� Galactoseamia
� Immune diseasesImmune diseasesImmune diseasesImmune diseases as: Atopic dermatitis , Myotonic dystrophy
� Drugs intake rugs intake rugs intake rugs intake : Prolonged use of steroid
� Drugrugrugrug ToxicityToxicityToxicityToxicity: e.g. Ergot – Thalium – Di-nitro-phenol
� Doooooooodoooooooodoooooooodooooooood ! (Parasitic infestation)(Parasitic infestation)(Parasitic infestation)(Parasitic infestation): especially ankylostoma (was common in Egypt)
d.t.: (i) anaemia (↓ nutrition) (ii) toxins of worm
� IrraIrraIrraIrraDiationiationiationiation: by X-ray
MechanismMechanismMechanismMechanism
The metabolic disturbance is d.t.:
(1)(1)(1)(1) Diffusion of toxins
(2)(2)(2)(2) Interference with lens nutrition
81
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
� If the complicated cataract is d.t. a local
� If the complicated cataract is d.t. a general
Except, High Myopia
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
local disease � Unilateral Cataract
general disease � Bilateral Cataract
High Myopia (which is a local disease)� Bilateral Cataract.
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Cataract. ��
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Clinical picture:Clinical picture:Clinical picture:Clinical picture:
1- History : : : :
���� Age:Age:Age:Age: Any age ���� HistoryHistoryHistoryHistory of any local eye disease or general disease. 2- Examination
- General examination:General examination:General examination:General examination: for any general disease
- Local examination:Local examination:Local examination:Local examination:
� � Visual acuity : always less than expected from the density of cataract�
� � Signs of other local disease e.g. glaucoma, iridocyclitis ….…
� � Lens ���� EarlyEarlyEarlyEarly shows : (1) PoPoPoPosterior cortical opacity : this site is due to
No epithelium lining to the posterior capsule.
� Very thin posterior capsule.
(2) PoPoPoPoly chromatic luster: due to diffraction of the slit lamp light by the
granular opacity "cholesterol"�
����LateLateLateLate shows : chalky white lenschalky white lenschalky white lenschalky white lens (due to Ca deposition)
� � Retinal function tests: often bad
3- Investigations: e.g. ultrasonography & retinal functions tests.
D.D. D.D. D.D. D.D.
Senile Cataract Complicated cataract
History of local or general diseaseHistory of local or general diseaseHistory of local or general diseaseHistory of local or general disease -ve +ve
AgeAgeAgeAge Above 50 years Any age
Opacity: Opacity: Opacity: Opacity: ---- EarlyEarlyEarlyEarly
---- LateLateLateLate
Grayish sectors
Grayish white
Posterior cortical "Saucer shapeSaucer shapeSaucer shapeSaucer shape"
Chalky white
Polychromatic lusterPolychromatic lusterPolychromatic lusterPolychromatic luster Not present Present
Local examinationLocal examinationLocal examinationLocal examination Free May show a local disease
RetRetRetRetinal final final final functionunctionunctionunction Good Often bad
PrognosisPrognosisPrognosisPrognosis Good Bad
ManagementManagementManagementManagement: : : : According to CauseCauseCauseCause & AgeAgeAgeAge
EEEExample:xample:xample:xample: CCCComplicated cataract with omplicated cataract with omplicated cataract with omplicated cataract with iridocylitisiridocylitisiridocylitisiridocylitis ��
1. TTT of iridocylitis ( The patient become stable for 6 months )
2. We give CorFicosteroids for 10101010 days
3. Do cataract operation ( Under the umbrella of Corticosteroids)
82
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
YAG laser capsulotomyYAG laser capsulotomyYAG laser capsulotomyYAG laser capsulotomy
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Definition:
It is an opacity in the pupillary area, seen
� Cataract operation (ECCE) �
OR
� Perforating trauma (with capsular injury)
Composition:
After cataract is composed of :
Part of anterior capsule & posterior capsule
� Remnants of lens matter
Hge & exudates
� Proliferated subcapsular epithelium
Clinical Types:
Posterior capsular opacification ( PCO
� Sommering ring [It is opaque ring behind the iris due to adherence of the ant
Posterior capsules with lens fibres in
Elschnig pearls [It is proliferation of t
transparent pearls like soap bubblespearls like soap bubblespearls like soap bubblespearls like soap bubbles
Complications:
� of vision
� Iridocyclitis
Posterior synechia.
� 2ry glaucoma
Treatment:
���� If thin � YAG laser Capsulotomy
���� If thick with :
a. NO posterior synechia : do
b. Posterior synechia
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ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
cataract After
pillary area, seen After:
�
Perforating trauma (with capsular injury) �
Part of anterior capsule & posterior capsule
Proliferated subcapsular epithelium
Posterior capsular opacification ( PCO ) [ Thin after cataract ] ( Most common
opaque ring behind the iris due to adherence of the ant
capsules with lens fibres in-between ]
[It is proliferation of the equatorial subcapsular epithelium
pearls like soap bubblespearls like soap bubblespearls like soap bubblespearls like soap bubbles in the pupillary area along the posterior
otomy.
posterior synechia : do capsulectomy
Posterior synechia : do capsule-iridectomy
83
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Most common )
opaque ring behind the iris due to adherence of the anterior &
he equatorial subcapsular epithelium with formation of
erior capsule.]
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Anterior polar cataract formation
Types
§§§§ ZAPT-Sut-blue.com §§§§
- Zonular
- Anterior X Posterior
- Total
ــــــــــــــــــــــــــــــــــــــــــــــــ
- Sutural
- Blue dot
- Coronary
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
since birthin lens OpacityOpacityOpacityOpacity Definition Definition Definition Definition
Etiology: Etiology: Etiology: Etiology:
1) Heredddditary: usually A.D. (autosomal- dominant)
2) MalnutGition of mother during preg_ancy as Vitamin
3) IntGauterine infection ( as Rubella infection )
4) Teratogenic DDDDrugs
5) Irraddddiations.
Characters of congenital cataract: Characters of congenital cataract: Characters of congenital cataract: Characters of congenital cataract:
1) Commonly Bilateral.
congenital anomaliesother eside it, B2) Commonly
3) Commonly Stationary.
4) Soft cataract.
5) HereditarS may play a role.
Types: Types: Types: Types:
Etiology:Etiology:Etiology:Etiology:
Delayed formation of the anterior chamberDelayed formation of the anterior chamberDelayed formation of the anterior chamberDelayed formation of the anterior chamber
subcapsular epithelium at the anterior pole
Opacity.
Clinical picture:Clinical picture:Clinical picture:Clinical picture:
, but if present:ABSENTABSENTABSENTABSENTUsually :SymptomsSymptomsSymptomsSymptoms �
� SignsSignsSignsSigns: Small opacity at the anterior pole in one of these shapes
at anterior pole. (Immediate separation) shaped opacity DiscDiscDiscDisc1)
. (Delayed separation)opacity PyramidalPyramidalPyramidalPyramidal2)
. ( no separation )opacity glassglassglassglass-HourHourHourHour3)
. (anterior polar + anterior cortical + clear fibers in between )opacity ReduplicatedReduplicatedReduplicatedReduplicated4)
Congenital Cataract
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� ) DevelopmentalDevelopmentalDevelopmentalDevelopmental( shortly after birth, or since birth
dominant)
2) MalnutGition of mother during preg_ancy as Vitamin DDDD & Ca deficiency.
�������infection )
Characters of congenital cataract: Characters of congenital cataract: Characters of congenital cataract: Characters of congenital cataract:
.congenital anomalies
Delayed formation of the anterior chamberDelayed formation of the anterior chamberDelayed formation of the anterior chamberDelayed formation of the anterior chamber � prolonged contact between cornea & lens �
subcapsular epithelium at the anterior pole � proliferation & formation of a mass of cells with Ca deposition
, but if present:
1) Day blindness as the opacity is central. �
2) Diminution of vision.
or pole in one of these shapes
at anterior pole. (Immediate separation)
. (Delayed separation)
. ( no separation )
. (anterior polar + anterior cortical + clear fibers in between )
Congenital Cataract
Anterior polar cataract
84
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
� irritation of anterior
proliferation & formation of a mass of cells with Ca deposition �
. (anterior polar + anterior cortical + clear fibers in between )
P O W
2 4 5
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Hyaloid artery
LeucoLeucoLeucoLeuco----coria = White pupil = coria = White pupil = coria = White pupil = coria = White pupil =
A. Retinoblastoma A. Retinoblastoma A. Retinoblastoma A. Retinoblastoma ���
B. B. B. B. NOT NOT NOT NOT RetinoblastomaRetinoblastomaRetinoblastomaRetinoblastoma
1. Congenital cataractCongenital cataractCongenital cataractCongenital cataract.
2. Cyclitic membraneCyclitic membraneCyclitic membraneCyclitic membrane
3. PHPV PHPV PHPV PHPV ( persistent hyperplastic primary vitreous ) : congenital anomaly with fibrosis of the anterior vitreous.
4. Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis
5. EndophthalmitisEndophthalmitisEndophthalmitisEndophthalmitis
6. Organized vitreous hemorrhageOrganized vitreous hemorrhageOrganized vitreous hemorrhageOrganized vitreous hemorrhage.
7. Coloboma Coloboma Coloboma Coloboma of the retina& choroids showing sclera.
8. RetinalRetinalRetinalRetinal dysplasiadysplasiadysplasiadysplasia : d.t. chromosomal defect.
9. ROPROPROPROP ( retinopathy of prematurity )
Exudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis): : (= diseasediseasediseasedisease Coat'sCoat'sCoat'sCoat's10.
breakdown of the blood-retinal barrier
macrophages into the retina and subretinal space
11. RDRDRDRD (especially if extensive)
12. PosteriorPosteriorPosteriorPosterior polepolepolepole toxocariasistoxocariasistoxocariasistoxocariasis: granuloma caused by toxocara
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coria = White pupil = coria = White pupil = coria = White pupil = coria = White pupil = Yellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eye
Causes:Causes:Causes:Causes:
( persistent hyperplastic primary vitreous ) : congenital anomaly with fibrosis of the anterior vitreous.
Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis Exudate or fibrosis of vitreous after chorioditis [ either : exudative or granulomatous as T.B. ]
of the retina& choroids showing sclera.
: d.t. chromosomal defect.
( retinopathy of prematurity )
disease characterized by CongenitalExudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis): Exudative retinitis = Retinal telangiectasis):
retinal barrier in the endothelial cell � leakage of cholesterol
into the retina and subretinal space � Exudative retinal detachment.
: granuloma caused by toxocara- canis
Nodal point = Optical centreNodal point = Optical centreNodal point = Optical centreNodal point = Optical centre
Def.Def.Def.Def. A point of a lens through which a ray of light pass without
being bent (i.e. refracted).
Site :Site :Site :Site : Just in front of posterior pole of lens.
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Yellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eyeYellow reflex = Amaurotic cat's eye
( persistent hyperplastic primary vitreous ) : congenital anomaly with fibrosis of the anterior vitreous.
[ either : exudative or granulomatous as T.B. ]
disease characterized by
cholesterol crystals and lipid-laden
Nodal point = Optical centreNodal point = Optical centreNodal point = Optical centreNodal point = Optical centre
A point of a lens through which a ray of light pass without
front of posterior pole of lens.
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
D.D. D.D. D.D. D.D.
1) Acquired Cataract1) Acquired Cataract1) Acquired Cataract1) Acquired Cataract caused by a small central perforation. (MORE COMMONCOMMONCOMMONCOMMON) �
Acquired Congenital
At any age Since birth Age
+ ve - ve History of red eye
+ve -ve ( exceptexceptexceptexcept in hour-glass) �������� Corneal opacity
Unilateral Bilateral Side
2) Causes of 2) Causes of 2) Causes of 2) Causes of lllleucocoriaeucocoriaeucocoriaeucocoria = White pupil= White pupil= White pupil= White pupil ��......
::::TreatmentTreatmentTreatmentTreatment
»» If smallsmallsmallsmall opacity NOTNOTNOTNOT affecting the vision (common) � NONONONO TTT is needed.
»» If largelargelargelarge opacity affecting the vision (less common) � Visual iridectomy after mydriatic testVisual iridectomy after mydriatic testVisual iridectomy after mydriatic testVisual iridectomy after mydriatic test.
� of hyaloid artery. of remnantsPersistence ::::EtiologyEtiologyEtiologyEtiology
Clinical pictureClinical pictureClinical pictureClinical picture::::
of vision. �Marked : SymptomsSymptomsSymptomsSymptoms �
� Signs:Signs:Signs:Signs:
- Disc shaped opacity at posterior pole of lens.
- Marked � of vision � [as the opacity is near the nodal point] NOTNOTNOTNOT improved by mydriasis.
correction of aphakia.Lens extraction + ::::TreatmentTreatmentTreatmentTreatment
[ The most common type of congenital cataract [ The most common type of congenital cataract [ The most common type of congenital cataract [ The most common type of congenital cataract �������������������� ]]]] �
� nucleus)fetal (aroundOpacity of one or more lamellae of lens ::::DefinitionDefinitionDefinitionDefinition
Unknown ::::EtiologyEtiologyEtiologyEtiology
� Hereditary
� Malnutrition of mother during pregnancy especially deficiency of Vit D & Ca.
: The child osten has : 1) Rickets. 2) Abnorcalities in percanent teeth. EvidenceEvidenceEvidenceEvidence
Signs:Signs:Signs:Signs: Lens opacity is composed of : Central disc � Projections ( riders )
[Giving the appearance of: Steering wheel of a ship or Cart Steering wheel of a ship or Cart Steering wheel of a ship or Cart Steering wheel of a ship or Cart wheelwheelwheelwheel] �
Posterior polar cataract
Zonular cataract = Lamellar Cataract
85
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
" Rubella is a trivial infection,
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
" Rubella is a trivial infection, Except in pregnant women ! " Dr. Mostafa AkarDr. Mostafa AkarDr. Mostafa AkarDr. Mostafa Akar
SutureSutureSutureSuture in FETAL Lensin FETAL Lensin FETAL Lensin FETAL Lens
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Dr. Mostafa AkarDr. Mostafa AkarDr. Mostafa AkarDr. Mostafa Akar
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
to mother in infection RubellaRubellaRubellaRubella ::::EtiologyEtiologyEtiologyEtiology
Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :
1) Risk of anesthesia ( d.t. associated cardiac anomalies )
2) VirLs become dorcant inside the eye for
( i.e. If the operation is done
They are discovered accidentally during routine examination & do
5) Sutural Cataract (Opacity at the YYYY Suture)
6) Blue dot = Punctate (Small dots scattered in
7) Coronary cataract (Club shaped opacity at the
Clinical picture of congenital cataract:Clinical picture of congenital cataract:Clinical picture of congenital cataract:Clinical picture of congenital cataract:
( given by mother )( given by mother )( given by mother )( given by mother ) :Symptoms
» White pupil
» Child does NOTNOTNOTNOT see well.
Symptoms of complications [ e.g. abnormal eye movement or deviation of eye ] +»
Signs: One of the previous types is seen +
Leucocoria (White pupil) …….. ……… D.D.D.D.D.D.D.D.
Bilateral Opacity
��� Mental Retardation ( MR )
��� Nystagmus (opacity interferes
with foveal development that occurs
in 1st 3 months)
Leucocoria is a retinoblastoma until proved otherwise
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ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
� trimester. stststst
1111to mother in
Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :Note : The operation is RISKY to patient because :
1) Risk of anesthesia ( d.t. associated cardiac anomalies )
2) VirLs become dorcant inside the eye for 2222----3 years3 years3 years3 years
( i.e. If the operation is done � endophthamitis )
They are discovered accidentally during routine examination & do NOTNOTNOTNOT affect the vision.
Suture)
dots scattered in lens)
shaped opacity at the equator)
Clinical picture of congenital cataract:Clinical picture of congenital cataract:Clinical picture of congenital cataract:Clinical picture of congenital cataract:
Symptoms of complications [ e.g. abnormal eye movement or deviation of eye ]
+ signs of complications [ Nystagmus, squint or ambylopia ]
Leucocoria (White pupil) …….. ………
Total cataract
Other Types
(opacity interferes
with foveal development that occurs
Unilateral opacity
�� Squint
Or
�� Amblyopia
(Irreversible after 6 years)
Complications �
Leucocoria is a retinoblastoma until proved otherwise
86
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
affect the vision.
or ambylopia ]
Unilateral opacity
Amblyopia
(Irreversible after 6 years)
Leucocoria is a retinoblastoma until proved otherwise
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Operate as early as possibleas early as possibleas early as possibleas early as possible
Dense Opacity
Operate Early:
Before the 3rd month to avoid nystagmus.
Visual acuity
.With Glasses
Give Glasses
Visual Acuity of 6/18 in presence of accommodation is Better than
Asses the Asses the Asses the Asses the
( child < 2 years ) methodsmethodsmethodsmethods ObjectiveObjectiveObjectiveObjective1)
► Red Reflex
► Fundus examination
► Optokinetic nystagmus ( On looking to movable object e.g. Catford drum )
► Preferential looking ( child prefers to look to stripped cards )
► VEP ( Visual evoked potential ) : Recording electrical activity of occipital cortex.
( child > 2 years ) :methodsmethodsmethodsmethods SubjectiveSubjectiveSubjectiveSubjective2)
♦ Hand test.
♦ Sheridan cards.
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as early as possibleas early as possibleas early as possibleas early as possible to avoid dense amblyopia (before 6 yearsbefore 6 yearsbefore 6 yearsbefore 6 years
to avoid nystagmus.
dense opacityNot
Wait until the patient can tell about his visual
acuity ( about 6 years )
.Visual acuity ≥ 6/18 Visual acuity
Do the Operation
Treatment
Unilateral cases
Bilateral cases
.After Mydriasis
Do Visual iridectomy
in presence of accommodation is Better than
accommodation.
by :by :by :by : visual acuityvisual acuityvisual acuityvisual acuity & the& the& the& the opacityopacityopacityopacityAsses the Asses the Asses the Asses the
( child < 2 years )
Fundus examination
Optokinetic nystagmus ( On looking to movable object e.g. Catford drum )
Preferential looking ( child prefers to look to stripped cards )
VEP ( Visual evoked potential ) : Recording electrical activity of occipital cortex.
( child > 2 years )
ـــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
before 6 yearsbefore 6 yearsbefore 6 yearsbefore 6 years )
dense opacity
until the patient can tell about his visual
.6/18˂ Visual acuity
�������� Do the Operation
without in presence of accommodation is Better than 6/6
Optokinetic nystagmus ( On looking to movable object e.g. Catford drum )
VEP ( Visual evoked potential ) : Recording electrical activity of occipital cortex.
Crystalline lensــــــــــــــــــــ
Dr. Ahmed Omara
Cataract extraction1)
A )A )A )A )----Aspiration ( IAspiration ( IAspiration ( IAspiration ( I ----A. Irrigation A. Irrigation A. Irrigation A. Irrigation
� Procedure:
2 mm limbal incision. �
AspirationAspirationAspirationAspiration of lens matter ( with simultaneous )
� Complication:
PCO (Posterior Capsule Opacification ).
� RD (Retinal Detachment ) Less common.
Mild iridocylitis, 2ry
glaucoma.
B.Pars plana lensectomy:B.Pars plana lensectomy:B.Pars plana lensectomy:B.Pars plana lensectomy:
� Procedure:
Pars plana incision. �
� Advantage:
NONONONO PCO (Posterior Capsular Opacification)
� Used in posterior polar cataract.
�Disadvantage:
RD is more common d.t very strong zonules in children.
Aim :Aim :Aim :Aim : To avoid amblyopia.
Optical TTTOptical TTTOptical TTTOptical TTT
GlassesGlassesGlassesGlasses
���
Anisometropia � AnisoKonia
Diplopia
UnilateralUnilateralUnilateralUnilateral
���� BilateralBilateralBilateralBilateral
N.B. N.B. N.B. N.B. Although IOL is the best correction of aphakia, but
Because of the rapid growth of the eye that occurs up to
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ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
2) CorGection of aphakia Cataract extraction
1) Cataract exFGaction1) Cataract exFGaction1) Cataract exFGaction1) Cataract exFGaction
� Anterior capsulotomy.
of lens matter ( with simultaneous ) IrrigationIrrigationIrrigationIrrigation by saline.
Capsule Opacification ). ������������
Detachment ) Less common. ���
glaucoma.
� Lens removal using vitrectomy machine or with knife.
PCO (Posterior Capsular Opacification)
Used in posterior polar cataract.
RD is more common d.t very strong zonules in children. ������������
2) CorGection of aphakia2) CorGection of aphakia2) CorGection of aphakia2) CorGection of aphakia
Optical TTTOptical TTTOptical TTTOptical TTT
Refractive surgeryRefractive surgeryRefractive surgeryRefractive surgery Contact lensContact lensContact lensContact lens
��� ���� AnisoKonia �
��� ����
IOL is the best correction of aphakia, but we postpone its use;we postpone its use;we postpone its use;we postpone its use;
of the eye that occurs up to 2 Years [Hence, Marked change in refraction]
Lines of Treatment
NowNowNowNow, we do posterior capsulotomy &
remove anterior vitreous face
87
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
2) CorGection of aphakia
Lens removal using vitrectomy machine or with knife.
Surgical TTTSurgical TTTSurgical TTTSurgical TTT
IOLIOLIOLIOL Refractive surgeryRefractive surgeryRefractive surgeryRefractive surgery
Aster 2 yearsAster 2 yearsAster 2 yearsAster 2 years
Aster 2 yearsAster 2 yearsAster 2 yearsAster 2 years
we postpone its use;we postpone its use;we postpone its use;we postpone its use;
Years [Hence, Marked change in refraction]
, we do posterior capsulotomy &
remove anterior vitreous face
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Weil Marchesania Marfan syndrome
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Ectopia lentis
).Subluxation or Dislocation( Displacement of lens from its position Definition
Etiology :
AcquiredAcquiredAcquiredAcquired CongenitalCongenitalCongenitalCongenital
1. Trauma ������������ 1. Marfan Syndrome
2. Degenerative myopia 2. Weil Marchesania syndrome
3. Hypermature cataract 3. Down syndrome Homocystinuria
Subluxation of lens Definition Displacement of lens d.t. partial absence OR tearing of zonules
[ The lens will be displaced towards the untorn portion of zonules & may undergo rotation ]
B4 ………as Etiology :
Clinical picture
Symptoms:
1.DDDDiminution of vision d.t. :
� Myopia ( d.t. increased lens curvature )
Astigmatism ( d.t. tilting of lens )
� Interference with accommodation.
� Complication
2. Uniocular DDDDiplopia : [ if the edge of lens is : Clear � Crosses the pupillary area ]
( One image through the phakic portion of the pupil & another through the aphakic portion )
Signs :
(1) A.C : Irregular depth
(2) Iris : Tremulous ( iridodonesis )
(3) Lens : - edge may be seen
- Tremulous ( phacodonesis )
Complication
2ry glaucoma. � Iridocyclitis. Cataract. (4) Dislocation.
Treatment
(1) if NO complications Nor diplopia � glasses
(2) If there are complications or diplopia � lens extraction
P O W
1 1 2
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Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Aphakia Definition: Absence of lens from pupillary area.
Symptoms:
- Defective visionDefective visionDefective visionDefective vision [ far & near ] defect is especially for near ( no accommodation )
- Blue or violet visionBlue or violet visionBlue or violet visionBlue or violet vision [ d.t. lens absence which was absorbing U.V. rays ]
Signs:
� + ve history of operation
Scar of pervious operation
� A.C. � Deep
� Iris : Tremulous iris + Iridectomy
� Pupil : Jet black ( No posterior capsule ) OR grayish in ECCE d.t. glistening posterior capsule OR Grayish
white d.t. after cataract
� Purkenje – Sanson image : absent of 2 out of 3 ������������
� Refraction : Shift towards hypermetropia
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Dislocation of the lens
Definition : Displacement of lens d.t. total absence OR tearing of the zonules.
Aetiology : as B4 ……..
Types :
1) Anterior Dislocation. [ lens in A.C. ]
2) Posterior Dislocation. [ lens in P.C. ]
3) Subconjunctival dislocation : ( lens lies under conjunctiva )
Anterior Dislocation ( Anterior Dislocation ( Anterior Dislocation ( Anterior Dislocation ( in A.C ))))
Clinical picture:
Signs :
� The lens becomes spherical with golden yellow edges which resemble a droplet of oildroplet of oildroplet of oildroplet of oil in A.C.
� pupillary block
Complication
2ry glaucoma d.t. pupillary block [glaucoma inversus] � Iridocyclitis. Cataract.
(4) Corneal opacification d.t. endothelium damage.
Management: Removal of lens through anterior approach after miosis.
Posterior Dislocation ( Posterior Dislocation ( Posterior Dislocation ( Posterior Dislocation ( in vitreous ))))
Clinical picture:
The same clinical picture of aphakia ……..
++++ dislocated lens can be seen in vitreous.
Fate : either;
Remains quite
� Absorbed
Leads to Complications: 2ry glaucoma. � Iridocyclitis. Cataract.
Management: Removal of lens through Posterior approach [ pars plana vitrectomy ]
89
Crystalline lensــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ
Ramadology ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Dr. Ahmed Omara
Opuft!