रसशाला V/s GMP

By Dr Sanand Ratnam Thekkayil Under the Guidance of Dr Vinay Chandra Shetty H.O.D Dept. of Rasa Sastra

रसशाला V/s GMP

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Word Meaning:

रस - पारद शाला - भवनम्

शाला is derived from the root word “शलगतॊ” (Dhatu

Roopavali)

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Cont… शाला तरुस्कन्दशाखा शाला भवनमि�ष्यते I (Sasvatha Nighantu)

शालाद्रुस्कन्द शाखाया�् गु्रहगेहैक देशयो: न झषे ( Medini Nighantu)

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Location of the Pharmacy:

रसशाला प्रकुव!त सव"बादाविववर्जि&'ते Iसव(षध�ये देशे रम्ये कूपस�न्विन्वते II ( Rasendra Chudamani 3/1,2)

विव�लोपवनप्रदेशगा�........... (Rasatarangini 1/ 13)रसशाला�् प्रवक्ष्यामि� रसेन्द्रस्य वरानने (Anandakanda 2/22) आतन्गरविहते देशे ध�"राज्ये...... ( R.R.S 7/1)

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Cont…Where there is no obstacles of any kind.Where all the medicinal herbs are available. beautiful well Equipped with equipments. Compound wall

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Working Area: A very beautiful and vivid description with

regards to the site and the building of ‘Rasa Sala’is found mentioned in the Rasa literature along with its working arrangements, various divisions, spiritual rituals, qualities of its employees and the types of equipments to be collected for completion of various Rasa operations and pharmaceutical processes and procedures.

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Cont…

Here the different types of pharmaceutical operations have been found divided on the basis of different directions to achieve highest success in these operations on account of the blessings of Gods ruling these directions.

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The working arrangements of ‘Rasa Sala’ have been divided into eight divisions:

Poorvadik (East) Agnikona (South East) Yamyabaga( South) Nairityakona( South West) Varunabaga(West) Vayavyakona(North West) Utharadigbaga(North) Isanakona( North East)

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शालाया: पूव"दिदक्भागे स्थापयेत् रसभैरव�् I (Rasatarangini 3/3)

The statue of ‘Rasa Bhairava’ should be installed in the Eastern direction of the factory.

Starting and entering point.

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Rasamandapam तत्स�ीपे स�े दीप्ते कत"व्य�् रस�ण्ड्प�् I अवितगुप्त�्.......... (R.R.S 6/14)

• Constructed in a plain and concealed area.• Eight pettaled lotus design• Centre, mercury is placed in a mortar.• Surrounding this mortar, a hexagonal design

is drawn

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Cont..Each corner -Diamond, Flourspar, Black

Mica,Magnatite, Borax and Earth worm extract.

Centre- Sulphur, Yellow orpiment, Green Vitreol, Realgar, Gamboze, Galena, Lapis lazuli and ochre are placed

End-Calamine, Iron pyrites, Copper -pyrites, Bismuth,

Blue vitreol, Stybnites, Corraline ore and peacock ore are placed.

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Installation of Rasalinga नीष्कत्रय�् ह�ेपत्र�् रसेन्द्र�्......... (R.R.S 6/17) Gold leaves - 3 Nishka (72 ratti or 4.5

grm) Parada - 9 Nishka (216 ratti or 13.5

grm) Rubbed with Nimba Juice( 3 hours) and Shiva

linga is prepared.

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Benefits of worshipping Rasalingam:

लिलङ्ग कोदि@सहस्रस्य यत्फल�् सम्यक् अर्च"नात् I तत्फल�् कोदि@गुणिEत�् रसलिलङ्गार्च"नाद्भवेत् II (R.R.S 6/19)• Equal to worshipping one thousand crore

Sivalingas.• Seeing, eradicate the sins acumalated due to

killing of thousand brahmins and lakhs of cows.• Touch, attain Moksha

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Method of Worship

आग्नेय्या�् श्रीअघोरेE �न्त्ररा&ेन र्चार्च"येत् I ( R.R.S 6/21) • Worshipped by chanting Aghora Mantra.

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वमिKक�ा"विन र्चाग्नेये....The operations related to the use of fire are

advised to be carried out in ‘Agnikona’ (South east direction) which is considered to be ruled by God Agni who by virtue of his being the God of fire keeps control on fire related works (operations) thus the success in such operations is always expected if such works are performed in this direction.

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नैर्ऋ" त्ये शस्त्रक�ा"Eी....The ‘Nairitya Kona’ (South west direction)

is advised for performing ‘Sastra Karmas’ like cutting, slicing etc.

As this direction is ruled by Raksasas (Demons) who are cruel in nature and keeps the control on sharp weapons /instruments.

Hence the cutting, slicing etc. operations invoving the use of sharp instruments if done in this direction may likely to be completed safely and successfully with the blessing of the Demons

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वारुEे क्षालनादिदक�् IThe Varuna bhaga (western part) of the

factory is advised for washing ,cleaning etc. works involving the use of water .

As this direction is ruled by God ‘Varuna’ who is considered to be the God of water resources , hence the operations invoving the use of water if done in this direction will never face water shortage and get completed successfully with the blessings of God Varuna.

 

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शोषE�् वायुकोEे र्च...The Vayavya Kona(North West directions)

is ruled by the God vayu,who is supposed to control wind blowing.

The drying operations of the drugs /materials/ and the preparations if done in this direction will never face blowing wind shortage and get dried easily with the blessings of God Vayu.

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वेधक�Nत्तरे तथा IIThe Uttara digbhaga (Northern part) is

governed by God Kuvera who is considered to be the God of ‘wealth and finances’ .

Hence the Vedha Karmas(Transformation operation of lower metals into higher metals) are advised to be done in this direction

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स्थापन�् लिसद्दवस्तूना�् प्रकुया"दीशकोEके IThe Isana Kona (North eastern direction)

is ruled by Lord Siva/rudra who is considered to be the creator of mercurial operations.

The transformed mercurial products and the other finished products if stored in this direction then their potency and effectiveness will be preserved for long time and there self life will be very prolonged one.

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Equipments:

• Koshtis• Storage Tanks• Bhastrikas(bellows)• Mettalic and Bamboo pipes.

सत्वपातनकोष्टीन्& गारकोमिष्ट�् सुशोभना� I (R.R.S 7/6)

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Cont…Vessels and utensils of different size (Gold,Iron,Copper,Bronze, leather and

stones)Different types of kandani(small pounder)Peshani(Bigger,flat stone for rubbing)Droni(Big cauldron)Mortars and pestles of different kindsTaptakhalva

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Fuels:लिशखिखत्रा पावकोलिर्च...... (R.R.S 7/18)Synonyms of Coal:

1. Shikitra2. Pavakochista3. Angara4. Kokila

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Cow-dung Cakes

Synonyms Pistaka Changana Chana Upala Utpala

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Appointment of Physician: • Who has studied Rasasastra well• He should have proper access to

NighantuSastra• Who is well versed in the languages of all

the(nearby) countries.• Amrita hasta (R.R.S 7/23)

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Qualities of Sisya:गुरुभक्त सदार्चारो लोभ�ायाविववर्जिे&Vते:I ( Anandakanda

2/7) Obey the GuruTruthfulStrong determination to workDevoid of pride and greed peaceful and always devoted in practising

mantra

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Attendant:Having good conduct and be clean Strong and courageous more industrious well born and more faithfull ( R.R.S 7/25)

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BalikarmaPerson who is strongTruthful Having Red eyes with black complexionCapable of warding off the evilspirits

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Dhatuvada:Rich personPossess all types of instruments follows the advice of Guru

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Kalini woman:Curly hairsBeautiful eyes like lotus Good Body stature

Kalini woman is extremely good in bringing about the success in Rasabandha and such other Rasayana process.

(R.R.S 6/33-37)

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Qualities of the King:धार्मि�'क: पापभीरुश्च बलवान्.... (Anandakanda 2/20)Kind to the peopleFear in पापStrongKnowledge in रसशास्त्रTruthful

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GOOD MANUFACTURING PRACTISE ( GMP)

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Importance of GMPGMP is an essential and significant step

taken by the government of India in improving the quality & standard of ASU (Ayurveda, Sidha & Unani)

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GMP are prescribed to ensure that: 1. Raw materials used in the manufacture of

the drugs are authentic of prescribed quality & are free from contamination.

2. The manufacturing process has been prescribed to maintain the standard.

3. Adequate quality control measures are adopted.

4. The manufactured drug which is released for sale is of acceptable quality.

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Cont…To achieve the objects listed above, each

licencee shall evolve methodology & procedure for following the prescribed process of manufacture of drugs, which should be documented as a manual & kept for references & inspection.

Building used for the factory shall conform the conditions laid down in the factories Act,1948.

Factory premises should have minimum covered area of 1200 sq.ft.

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Cont…Water System:There shall be validated system for treatment of water drawn from own or any other source torender it potable in accordance with standards specified by the Bureau of Indian standards

or Local Municipality.

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The manufacturing plant should have adequate space for:Receiving & storing raw materials.Manufacturing process area.Quality Control section.Finished goods store.Office.Rejected goods/drug store. Rest and Refreshment Rooms

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Specifications:Specification have made about the batch of

manufacturing, reference during the process of preparation etc.

specific records of the market complaints will also have to be maintained.

Provisions for quality control have also been made through a separate quality control section.

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Cont…One qualified person with degree in Aurveda,

Sidha & Unani should be posted in the quality control section. This is the mandatory requirement. In addition , they may have experts in pharmacy, pharmacognosy & chemistry.

The quality control will be as per the prescribed pharmacopeial standards of ASU drugs. However where tests are not available, the test is enforced according to the manufacturers specification or other information available may be given.1/28/2011

Cont….Specification for other manufacturing

activities like pill making, capsuling etc have been specified.

The GMP has also recommended the various equipments required for carrying out various manufacturing procedures.

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Equipments: Disintegrator Micropulverizer Juicer Granulator Tablet Punching Machine Heater Cutter Grinder

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Disposal of Waste:• The disposal of sewage and effluents from

the manufactory shall be in conformity with the requirements of Environment Pollution Control Board.

• Effluent water treatment plant.• All Biomedical waste shall be destroyed as

per Bio medical Waste Rules,1996.

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The implementation of GMP will increase the faith in public about the

quality of ASU drugs.

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Future:

This step of government will therefore increase the domestic as well as export business of ASU drugs.

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ConclusionIn Rasasala, Medicines are prepared

according to classics and in traditional way.In GMP certified Pharmacy, Medicines are

prepared in Bulk. Preservatives.Quality of Medicines.

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THANK YOU

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