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Sino Biological Inc. 北京义翘神州生物技术有限公司

GENE|PROTEIN|ANTIBODY|ELISA

北京义翘神州生物技术有限公司（Sino Biological Inc.）成立于 2007 年，是北京市高新技术企业，是科技部认定的“现代服务业创新发展示范企业”。重点从事重组蛋白、抗体、细胞因子、cDNA 、ELISA 试剂盒、转染试剂等产品的研发和生产。产品应用于免疫学、肿瘤、神经生物学、干细胞、病毒等相关领域的生命科学研究以及药物研发。同时，义翘神州也致力于生物技术药物如单克隆抗体、重组蛋白药物、病毒疫苗、快速诊断试剂等的研究开发服务。

义翘神州拥有全球领先的重组蛋白药物和单克隆抗体生产工艺和技术平台。每年新增重组蛋白、抗体近 2000 种，已成为全球十强药企在重组蛋白和单克隆抗体研究开发领域的首选技术服务供应商，产品均产自义翘神州高度集中化的生产实验室，质量控制严格，绝无代工产品。

义翘神州产品已经销往全球 87 个国家和地区，得到了世界范围内 11500 家用户的认可。义翘神州生产的重组蛋白 80% 以上为真核表达，更接近天然蛋白的性质，因此具有更好的生物活性；单抗产品检测灵敏度比国际主流试剂供应商产品高 10-100 倍。相比国外品牌，义翘神州保证科研、企业用户以更低的费用和更快的配送服务获得更高品质的科研试剂。

CONTENTS

产品优势 .......................................................................................................... 2

产品列表 .......................................................................................................... 4

药物靶点 .......................................................................................................... 14

药物靶点文献例证 ......................................................................................... 16

目录

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02 产品优势义翘 CD 分子

兔单抗&鼠单抗可供选择

高亲和力，高灵敏度

多组织验证

蛋白纯度高

满足多种功能应用

现货库存，24h

内发货

涵盖热点药物靶点

生物活性高

Human CD32a binding to IgG10374-H08H

0

1

2

3

4

OD4

50nm

-B

1E-3 0.01 10human lgG1 Con. (ug/ml)

5

0.1 1human lgG1 Con.(μg/ml)

Human CD16a (158V) binding to IgG

0

1

2

3

4

OD4

50nm

-B

1E-3 0.01 10human lgG1 Con. (ug/ml)

10389-H08H1

0.1 1human lgG1 Con.(μg/ml) FGFR1-Fch Con.(ng/ml)

CD331(FGFR1)Fms-like tyrosine kinase

10616-H03H

1E-3

40

50

60

70

80

90

0.01 0.11 10 100 10001


03产品优势多组织验证同靶点：鼠单抗 & 兔单抗其他 IHC 引用范例

IP 引用范例

target-cell:LAMP1-MCF7Cat.No.11215-MM07

target-cell:GCSFR-MCF7Cat.No.10218-MM03

target-cell:E-CAD-P-MCF7Cat.No.10204-MM08

target-cell:CD340-SKBR3Cat.No.10004-R511

target-cell:CD321-A431Cat.No.10198-MM04

target-cell:CD9-HelaCat.No.11029-MM01

E-cadherin-pAb-1ug-IHC-P, Human Liver

Cat.No.10204-T58-100

CEACAM1-5ug-intestine, Rabbit mAb

Cat.No.50571-R030-50

mCD34-0.2ug-heartCat.No.50589-T24-50

E-cadherin-pAb-1ug-IHC-P, colon-carcinomaCat.No.10204-T58-100

CEACAM1-15ug-liver,Mouse mAb

Cat.No.10822-MM02-50

B7-1-1ug-lungCat.No.10698-T24-100

c-KIT-3ug-IHC-P, skinCat.No.11996-R351-100

B7-H1-5ug-placenta,Rabbit mAb

Cat.No.10084-R015-50

VEGFR2-1ug-kidneyCat.No.10012-T24-100

c-KIT-3ug-IHC-P, breast-cancer

Cat.No.11996-R351-100

B7-H1-30ug-placenta,Mouse mAb

Cat.No.10084-MB55-100

ANXA6-0.2ug-pancreasCat.No.100742-T40-100


04 产品列表 (CD1-30)Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD1b T6 11831-H02H WBCD1d R3G1 11009-H08H 50188-M08HCD2 T11, LFA-2, SRBC-R, Erythrocyte receptor, LFA-3R 10982-H08H WB, ELISA, IHC-P, FCM 50537-M08H WB, ELISA, IHC-PCD3gd T3D, OKT3 10981-H08H WB, ELISA, IHC-P, IP 50390-M02HCD3e T3E, TCRE 10977-H08H WB, ELISA, IHC-P, FCM, IPCD4 T4 10400-H03H WB, ELISA, IHC-P, FCM 50134-M08H ELISA, IHC-PCD5 T1, Tp67, LEU1 11027-H08H WB, ELISA, IHC-P, FCM, IP 50403-M08H WB, ELISA, IHC-P, FCM, ICC/IFCD6 T12, OX52, TP120 50711-M02H ELISA, FCM, ICC/IFCD7 LEU 9, GP40, TP41 11028-H08H WB, ELISA, IHC-P, IP 50393-M08H ELISACD8a T8, Leu-2, MAL 10980-H08H ELISA, IHC-P, FCM 50389-M08H ELISA, FCM, ICC/IFCD8b CD8B1 11031-H02H ELISA, IHC-PCD9 p24, MRP-1, 5H9 antigen, MIC3, TSPAN29, GIG2 11029-H08H FCM, ICC/IFCD10 CALLA, NEP, gp100, Neprilysin, SFE, MME, EPN 10805-H01H ELISA, FCM 50218-M07HCD11c p150, 95, CR4, integrin αX, LFA-1A, ITGAL CT017-H2508HCD13 Aminopeptidase N, APN, ANPEP,PEPN 10051-H08H WB, ELISA, IHC-P, IP 50001-M08H ELISA, IHC-PCD14 LPS-R 10073-H01H ELISA, IHC-P, FCM 50023-M03H ELISA, FCM, ICC/IFCD16a FcγRIIIA, FCGR3A, FCG3, FCGR3, IGFR3 10389-H08H ELISA, IHC-P 50326-M08H CD16b FcγRIIIB, FCGR3B, FCG3, FCGR3, IGFR3 11046-H08H ELISA, IHC-PCD18 Integrin β2, ITGB2, MFI7 CT015-H2508HCD19 B4, Leu-12 11880-H08H ELISA, IHC-P, IP 50510-M08HCD20 B1, Bp35, MS4A1 11007-H07H2 WB, ELISA, IHC-P, FCMCD21 C3DR, CR2, EBV-R 10811-H08H WB, ELISA, IHC-P, IPCD22 BL-CAM, Siglec-2, Leu-14 11958-H08H ELISA 51177-M08HCD23 FcεRII, BLAST-2, FCER2, CLEC4J 10261-H07H WB, ELISA, IHC-P 50695-M07H ELISA, FCM, ICC/IFCD24 BA-1, Nectadrin 11030-H02H 50717-M02H CD25 Tac, p55, IL2RA 10165-H02H ELISA 50292-M08H ELISA, FCMCD26 DPP IV, DPP4, ADABP, ADCP2 10688-H01H 50718-M01HCD27 T14, TNFRSF 7, CD27L receptor 10039-H03H ELISA, IHC-P, FCM 50110-M03H ELISA, IHC-P, FCM, ICC/IFCD28 Tp44, T44 11524-H02H ELISA 50103-M03H WB, ELISACD29 Integrin β1, ITGB1, FNRB CT014-H2508HCD30 Ki-1, TNFRSF8 10777-H03H WB, ELISA, IHC-P, FCM, IP*IHC-P: 免疫组化（石蜡切片）; WB: 蛋白免疫印迹 ; FCM: 流式细胞实验 ; ELISA: 酶联免疫吸附试验 ; ICC/IF: 免疫细胞化学 / 免疫荧光实验 ; IP: 免疫共沉淀实验


05产品列表 (CD31-59)Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD31 PECAM-1 10148-H02H WB, ELISA, IHC-P, FCM, IP 50408-M08H ELISACD32a FcγRII, FCGR2A 10374-H08H WB, ELISA 50030-M08HCD32b FcγRII, FCGR2B 10259-H08H WB, ELISA, IHC-P, FCM 50712-M02HCD33 p67, Siglec-3 12238-H08H ELISA 50589-M08H ELISACD34 10103-H02H ELISA ELISA, IHC-P, FCMCD35 CR1, C3b/C4b receptor IHC-PCD36 GPIV, GP3B, GP4 10752-H08H WB, ELISA, IHC-P, FCM 50422-M03HCD37 TSPAN26 WB 50719-M01HCD38 T10, ADP ribosyl cyclase 1 10818-H08H WB, ELISA, IHC-P, IP 50191-M08H ELISA, IHC-P, FCMCD39 NTPDase 1, ENTPD1 10909-H08B 50398-M08B ELISACD40 TNFRSF5 10774-H03H WB, ELISA, FCM, ICC/IF 50324-M03HCD42c GPIbb 10742-H08HCD43 Leukosialin, sialophorin, SPN 50735-M02HCD44 H-CAM, Pgp-1, Epican, HUTCH-I, LHR, ECMR-III 12211-H08H WB, ELISA, IHC-P, FCM, ICC/IFCD45 LCA, T200, B220, PTPRC 10086-H02H ELISA, FCM 50713-MCCBCD46 MCP, TLX 12239-H08H WB, ELISA, IHC-P, FCM, ICC/IF, IPCD47 IAP, MER6 12283-H02H ELISACD48 Blast-1, BCM1 10797-H08H WB, ELISA, FCM, IP 50415-M08H ELISA, FCM, ICC/IFCD49b VLA-2, TGA2 WBCD49c VLA-3, TGA3 IHC-PCD49e VLA-5, TGA5 CT014-H2508HCD49f VLA-6, TGA6 CT013-H2508H IHC-PCD50 ICAM-3 10333-H03H WB, ELISA, IHC-P, FCM, IPCD51 Vitronectin receptor, ITGAV, MSK8 IHC-PCD52 CAMPATH-1, HE5 15105-H02H 50721-M02HCD53 Tetraspanin-25, MOX44 50722-M07HCD54 ICAM-1 10346-H03H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50440-M03H ELISA, IHC-P, FCMCD55 DAF 10101-H02H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50468-M08H ELISA, FCM, ICC/IFCD56 NCAM1 10673-H08H WB, ELISA, IPCD58 LFA-3 12409-H08H ELISACD59 Protectin, MAC- inhibitor 12474-H08H WB, ELISA, IP 50724-M08H*IHC-P: 免疫组化（石蜡切片）; WB: 蛋白免疫印迹 ; FCM: 流式细胞实验 ; ELISA: 酶联免疫吸附试验 ; ICC/IF: 免疫细胞化学 / 免疫荧光实验 ; IP: 免疫共沉淀实验


06Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD61 GPIIIa, ITGB3, GP3A IHC-PCD62E E-selectin, ELAM-1, SELE 10335-H03H WB, ELISA, FCM 50736-M08H ELISACD62L L-selectin, LECAM-1, SELL 11838-H08H ELISA 50045-M03H ELISA, IHC-P, FCMCD62P P-selectin, PADGEM, SELP, LECAM3 13025-H08H ELISA 50737-M08H ELISACD63 LIMP, LAMP-3, MLA1 11271-H08H ELISA, IHC-P, FCM 50557-MNCHCD64 FcγRI, FCGR1A 10256-H08H 50086-M08HCD66a BGP-1, NCA-160, CEACAM1 10822-H03H WB, ELISA, IHC-P, FCM 50571-M08H ELISA, IHC-P, FCM, ICC/IFCD66b CD67, CGM6, CEACAM8 11729-H08H ELISA, FCMCD66c NCA, CEACAM6 10823-H08H ELISA, FCMCD66d CGM1, CEACAM3 11933-H08H ELISA, FCMCD66e CEA, CEACAM5 11077-H03H ELISA, IHC-P, FCMCD66f PSG, Sp-1, PSBG1 15378-H08HCD68 Macrosialin, gp110, KP1 11192-H03H ELISA, IHC-PCD69 AIM, CLEC2C, EA1 11150-H08H WB, ELISA, IP 50731-M08HCD70 Ki-24, CD27L 10780-H01H 51129-M04HCD71 T9, TFRC 11020-H07H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50741-M07H ELISACD72 Lyb-2, Ly-19, Ly-32 50732-M08HCD73 5’-nucleotidase, NT5E 10904-H08H WB, ELISA, IP 50231-M08H ELISACD74 LN2, Ii, DHLAG 11091-H07H WB, ELISA, IHC-P, FCM, IPCD75 ST6GAL1, Sialyltransferase 1 11590-H07H WB, ELISA, IHC-P, IP 50740-M07HCD77 Gb3, Pk blood group, BLA WBCD79a MB1, IGA 13208-H08H WB, IHC-P 50734-M02HCD79b B29, IGB 50754-M08HCD80 B7, B7-1, BB1 10698-H03H WB, ELISA, IHC-P, FCM 50446-M08H ELISACD81 TAPA-1, Tetraspanin-28 14244-HNCH 50743-M04HCD82 R2, KAI1, Tetraspanin-27 12275-H08H WB, ELISA, IHC-P,IPCD83 HB15 11763-H08H WB, ELISA, IHC-P 50694-M08H ELISACDw84 SLAM5 10100-H08H WB, ELISA 50757-M08H ELISACD85a LILRB3, ILT5, LIR3 11978-H08H ELISA, FCM 50760-M08H ELISA, ICC/IFCD85c LILRB5, LIR8 IHC-PCD85d LILRB2, ILT4, LIR2, MIR10 14132-H08H

产品列表 (CD61-85)

*IHC-P: 免疫组化（石蜡切片）; WB: 蛋白免疫印迹 ; FCM: 流式细胞实验 ; ELISA: 酶联免疫吸附试验 ; ICC/IF: 免疫细胞化学 / 免疫荧光实验 ; IP: 免疫共沉淀实验


07Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD85e LILRA3, ILT6, LIR4 16014-H08H ELISACD85f LILRA5, ILT11, LIR9 16059-H08HCD85i LILRA1, LIR6 WB, IPCD85j LILRB1, ILT2, LIR1 16014-H08H ELISA, FCMCD86 B70, B7-2, CD28LG2 10699-H03H ELISA, FCM 50068-M03H WB, ELISA, IPCD87 UPA-R, PLAUR, MO3 10925-H08H ELISA, FCM 50160-M03H ELISACD89 FcαR 10414-H08H ELISA, FCMCD90 Thy-1 WB 50461-M08H ELISA, IHC-PCD91 LRP1,A2MR,APOER 11665-HCCHCD93 C1qR, C1QR1, MXRA4 12589-H02HCD95 Apo-1, FASLG, APTL, TNFSF6 10217-H02H ELISA, FCM 50027-M08H ELISA, FCMCD96 TACTILE 11202-H08H ELISA 50758-M08H WB, ELISA, IHC-PCD97 11280-H08H WB, ELISA, FCM, ICC/IF, IPCD98 4F2hc, SLC3A2, MDU1 12206-H07H WB, ELISA, IHC-P, IP 50813-M07H WB, ELISA, IHC-PCD99 MIC2, E2 50520-M02HCD100 Semaphorin 4D, SEMA4D 11825-H08H WB, ELISA, FCM 50642-M08H ELISA, FCM, ICC/IFCD102 ICAM-2 10332-H03H WB, ELISA, IHC-P 50644-M02HCD105 Endoglin, ENG, END 10149-H02H WB,ELISA,IHC-P,FCM,ICC/IF 50407-M08H WB, ELISA, IHC-PCD106 VCAM-1, L1CAM 10113-H02H WB, ELISA 50163-M03H ELISACD107a LAMP-1 11215-H08H WB, ELISA, IHC-P, FCM, ICC/IF, IPCD107b LAMP-2 13555-H08H ELISA WB, ELISACD108 Semaphorin 7A, SEMA7A 50791-M08HCD111 PRR1, Nectin-1, HVEC 11611-H08H WB, ELISA, FCMCD112 PRR2, Nectin-2, HVEB 10005-H08H WB, ELISA, FCM, IP 50318-M08H WB, ELISA, IPCDw113 PVRL3, Nectin3 10852-H08H WB, ELISA, IHC-PCD114 GCSFR, CSF3R 10218-H02H ELISA, FCM, ICC/IFCD115 M-CSFR, c-fms 10161-H03H ELISA, IHC-P 50059-M08H ELISACD116 GM-CSFRα, CSF2RA 10701-H02H ELISA, FCMCD117 c-kit, SCFR, KIT 11996-H08H ELISA, IHC-P, FCM 50530-M02H ELISACD118 LIFR, gp190 10628-H08H ELISA, IHC-P 50423-M08H ELISACDw119 IFNγR 10338-H03H WB, ELISA, FCM 50705-M08H ELISA, FCM, ICC/IF

产品列表 (CD85-119)



08Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD120a TNFR-I, TNFRSF1A 10872-H03H WB, ELISA, IHC-P, ICC/IF 50496-M08H ELISACD120b TNFR-II, TNFRSF1B 10417-H03H ELISA 50128-M02H WB, ELISA, FCM, IPCD121a IL-1R type I, IL1R1 10126-H02H WB, ELISA 50807-M08H ELISA, FCMCDw121b IL-1R, type II, IL1R2 10111-H02H ELISA 51090-M08H ELISACD122 IL-2Rβ 10696-H02H 50792-M08HCDw123 IL-3R 10518-H08H WB, ELISA, IP 50810-M08HCD124 IL4RA, IL4R 10402-H08H ELISA 51180-M08H ELISACDw125 IL5RA, IL5R 10391-H08H 51154-M08BCD126 IL-6R, gp80 10398-H08H ELISA, ICC/IF 50280-M08H WB, ELISA, FCM, ICC/IFCD127 IL-7R 10975-H03H WB, ELISA 50090-M08H ELISACD130 IL-6Rβ, gp130, IL6ST 10974-H03H 50135-M03C ELISA, IHC-PCDw131 IL-3R common β, IL3RB, CSF2RB 10516-H03H ELISA, FCMCD132 IL2RG, Common γ 10555-H08B ELISA 50087-M03H ELISA, FCM, ICC/IFCD134 OX-40, TNFRSF4 10481-H03H ELISA 50808-M02HCD135 Flt3, Flk2 10445-H08H WB, ELISA, FCM, IP 51119-M08HCDw136 MSP-R, RON, PTK8 11608-H08H ELISA, IHC-PCDw137 4-1BB, TNFRSF9, ILA 10041-H03H ELISA 50811-M02HCD138 Syndecan-1, SDC 11429-H08H WB, ELISA, IHC-P 50641-M08H ELISA, IHC-PCD140a PDGFRα, PDGFRA 10556-H02H WB, ELISACD140b PDGFRβ, PDGFRB 10514-H08H ELISACD142 Tissue Factor, F3 13133-H08H WB, ELISA, FCM 50413-M08H WB, ELISA, FCMCD144 VE-Cadherin, Cadherin-5 10433-H03H ELISA, IHC-P 50192-M08H ELISACD146 MUC18, S-endo, MCAM 10115-H02H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50794-M08H WB, ELISA, IHC-P, IPCD147 Neurothelin, basoglin, Basigin, BSG 10186-H02H WB, ELISA, IHC-P, FCM, ICC/IF, IHC-Fr 50332-M03H ELISA, ICC/IFCD148 HPTP-eta, DEP1, PTPRJ 13165-H07E ELISACD150 SLAM, SLAMF1, IPO-3 10837-H08H WB, ELISA, IHC-PCD151 PETA-3, GP27, SFA-1, IHC-PCD152 CTLA-4 11159-H03H WB, ELISA 50503-M08H WB, ELISA, IPCD153 CD30L 10040-H01HCD154 CD40L, gp39, TRAP 10239-H08E ELISA 50327-M01H CD155 PVR, NECL-5 10109-HCCH WB, ELISA, FCM, ICC/IF, IP 50259-M08H ELISA, FCM, ICC/IF

产品列表 (CD120-155)



09Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD156a ADAM8 IHC-PCDw156c ADAM10 WBCD157 BST-1 10060-H08H ELISA 50319-M08H WB, ELISA, IPCD158a p58.1 13145-H08H ELISA, FCMCD158b2 NKAT-2 12828-H08H ELISACD158d KIR2DL4, KIR-103AS 13052-HCCSCD158z KIR3DL3 16055-H08H WB, IHC-PCD159a NKG2A, KLRC1 13905-H07H ELISA 50834-M07H ELISACD160 BY55 12191-H08H ELISA 50805-M02HCD161 NKR-P1A, KLRB1 50806-M07HCD162 PSGL-1 10490-H03H WB, ELISA, IHC-P 50770-M02H ELISA, IHC-PCD164 MGC-24, MUC-24 12260-H08H WB, IHC-P, IPCD166 ALCAM 10045-H08H ELISA, FCM, ICC/IF 50005-M03H ELISA, IHC-P, FCMCD167a DDR1 10730-H08H WB, ELISA, IP 50829-M08HCD167b DDR2 10209-H08H ELISA ELISA, IHC-PCD170 Siglec-5, CD33-like2, SIGLEC5, OB-BP2 11798-H02H ELISACD171 NCAM-L1, L1CAM 10140-H03H ELISA, IHC-P, FCM, ICC/IFCD172a SIRPγ, SHPS-1, SIRPA 11612-H08H WB, ELISA, FCM, IP 50956-M08H ELISACD172b SIRPβ, SIRB1 50816-M08HCD172g SIRPγ, SIRPB2 11828-H08H ELISACD176 Thomson Friedrenreich Ag 11019-H08H 50817-M08HCD177 NB1 glycoprotein, HNA-2a 14501-H08HCD178 FasL, CD95L 10244-H07Y 50854-MNAYCD180 RP-105 11370-H08H 50491-M02H WB, ELISA, IHC-PCD183 CXCR3 IHC-PCD185 CXCR5, BLR1 WBCD191 CCR1, MIP-1αR, RANTES-R WB, IHC-P, IPCD192 CCR2, MCP-1-R WBCD200 OX-2 10886-H03H WB, ELISA, IHC-P 50074-M08H ELISA, FCMCD201 EPC-R 13320-H08H ELISA, IHC-P 50874-M08H ELISACD202b Tie2, Tek 10700-H03H ELISA, FCM, ICC/IF 51087-M08H

产品列表 (CD156-202)



10Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD204 Macrophage scavenger-R, MSR1 10427-H07H WB, ELISA 50129-M07H ELISA, IHC-P, FCM, ICC/IFCD205 DEC-205 16490-H08HCD207 Langerin 13040-H01H WB,IPCD208 DC-LAMP, LAMP3 10527-H08H WB, ELISA, IHC-P, ICC/IF, IPCD209 DC-SIGN 10200-H01H WB, ELISA 50486-M07HCD212 IL-12-R β1, IL12RB1 11674-H08HCD213a1 IL-13-R α1, IL13RA1 10943-H03H ELISA, FCM 50088-M03H ELISACD213a2 IL-13-R α2, IL13RA2 10350-H03H 50061-M03H ELISACD215 IL15RA WBCDw217 IL-17R 10895-H03H WB, ELISA 50328-M08H ELISACDw218a IL-18Rα, IL-1Rrp 11102-H08H ELISA 50094-M03H ELISACDw218b IL-18Rβ, IL18RAP 10176-H02H ELISA 50845-M08BCD220 Insulin-R 11081-H08H ELISA, IHC-PCD221 IGF-1 R 10164-H08H ELISA, FCM, ICC/IFCD223 LAG-3 16498-H02HCD225 IFITM1, Leu-13, DSPA2a WB, IHC-P, IPCD226 DNAM-1, PTA-1, TLiSA1 10565-H03H ELISA 50232-M03H ELISA, FCMCD227 MUC1, EMA, PUM 12123-H02H ELISA, IHC-PCD228 Melanotransferrin, MFI2 50994-M08H ELISACD229 Ly-9 50504-M08H ELISA, FCM, ICC/IFCD230 Prion protein 12070-H02H 50878-M02HCD231 TALLA-1, A15, Tspan-7, 14031-H08H 50879-M08H ELISACD233 Band 3, SLC4A1 IHC-PCD235a Glycophorin A 16018-H08HCD236 Glycophorin C/D 15627-H07HCD238 Kell IHC-PCD239 B-CAM 10238-H02H WB, ELISA, IHC-P, IP 50960-M08HCD242 ICAM-4 13327-H02HCD244 2B4, NAIL 10042-H02H WB, ELISA, IPCD247 TCRz 13142-H09E WB, ELISA, IPCD249 Aminopeptidase AM, EAP 10554-H07H 50082-M07B

产品列表 (CD204-249)



11Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD252 OX40L, gp34 13127-H04HCD253 TRAIL, Apo-2L, TL2, TNFSF10 10409-H07E ELISA, IHC-P 50166-M07E WB, ELISACD254 TNFSF11, RANKL, OPGL, ODF 11682-H01H WB, ELISA, IP 50343-M01H CD256 APRIL, TALL-2, TRDL-1 10610-H01H 50965-M01H CD257 BLyS, BAFF, TALL-1 10056-H01H WB, ELISA, IPCD258 LIGHT, HVEM-L, TNFRSF14 10386-H07HCD261 TRAIL-R1, DR4 10408-H03H ELISA, FCMCD262 TRAIL-R2, DR5 10465-H03H ELISA, FCM 50412-M08H ELISACD264 DCR2, TRAIL-R4 10413-H08H WB, ELISA, IHC-P, IPCD265 RANK, TRANCE-R, ODFR 16078-H02H ELISACD266 TWEAK-R, FGF-inducible 14 10431-H01HCD267 TACI, TNFR SF13B 11937-H08H ELISACD268 BAFFR, TR13C 50353-M02HCD269 BCMA, TNFRSF13B 10620-H03H 50076-M01HCD270 HveA, TR2 10334-H08H ELISA 10567-M03HCD271 NGFR, p75 (NTR) 13184-H08H 50971-M08H ELISACD272 BTLA 11895-H02H 51060-M02HCD273 B7DC, PD-L2, PDCD1L2 10292-H08H WB, ELISA 50804-M08H ELISACD274 B7-H1, PD-L1 10084-H02H ELISA, IHC-P 50010-M03H ELISA, FCM, ICC/IFCD275 B7-H2, ICOSL, B7-RP1, GL50 11559-H08H ELISA, FCM 50190-M03H ELISACD276 B7-H3 11188-H08H ELISA, FCM, ICC/IF, IP 50973-M08H WB, ELISA, IPCD277 BTN3A1, butyrophilin SF3 A1, BTF5 15973-H02HCD278 ICOS, AILIM 10344-H03H 50466-M02H CD279 PD1, SLEB2 10377-H03H WB, ELISA, IHC-P 50124-M08H ELISA, IHC-PCD281 TLR1 10151-H08HCD282 TLR2 10061-H08B 50502-M08BCD283 TLR3 50161-M08H ELISACD284 TLR4 10146-H08B CD286 TLR6 IHC-PCD292 BMPR1A, ALK3, SKR5 10446-H03H ELISA, IHC-P 50078-M03H ELISA, IHC-PCDw293 BMPR1B, ALK6 10460-H02H 50004-M02H

产品列表 (CD252-293)



12Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD295 LeptinR, LEPR, OB-R 10322-H08H ELISACD297 ART4, dombrock blood group 51093-M08H WB, ELISACD299 DC-SIGN-related, LSIGN, DC-SIGN2, CLEC4M 10559-H01HCD300a CMRF35H, IRC1, IRp60M, CLM-8 12449-H08H ELISA, FCM 50675-M02HCD300b CLM-7, IREM3 13650-H02HCD300c CMRF35A, LIR, CLM-6 11832-H08H ELISA, FCMCD300e CMRF35L, CLM-2 15572-H02HCD300f CLM-1, IREM-1 16034-H02HCD300g CLM-9, TREM4 13365-H08HCD301 MGL, HML, CLEC10A 10821-H01H 50707-M07H ELISACD302 DCL1, BIMLEC 50706-M08H ELISACD304 BDCA4, neuropilin 1, CLEC4C, NRP1 10011-H02H ELISA, IHC-P, FCMCD305 LAIR1 13257-H08H 51030-M08H ELISA, IHC-PCD306 LAIR2 10868-H08H ELISACD307 IRTA2 11536-H08H ELISA 50947-M08H WB, ELISA, IPCD309 VEGFR2, KDR 10012-H02H ELISA, IHC-P 50998-M08H ELISACD314 NKG2D, KLRK1 10575-H07B ELISACD316 EWI2, PGRL, CD81P3, KASP,IGSF8, EWI-2, KCT-4 13435-H08H 51042-M08H CD317 BST2, HM1.24 13370-H01H 51043-M01H CD318 CDCP1, SIMA135 13262-H05H 51110-M08H ELISA, IHC-PCD319 CRACC, SLAMF7 11691-H08H ELISA 50201-M08H ELISACD320 FDC-SM-8D6, TCbIR 51138-M08H ELISACD321 JAM-A, JAM-1, PAM-1, F11R 10198-H08H WB, ELISA, FCM, ICC/IF, IP 50463-M02H CD322 JAM-B, JAM-2, VE-JAM 50464-M08H ELISACD324 E-Cadherin, Uvomorulin, CDH1 12550-H08H WB, ELISA, IHC-P, FCM, ICC/IF 50671-M08H WB, ELISA, IHC-P, IPCDw325 N-Cadherin, NCAD, CHD2 11039-H08H WB, ELISA, FCM, ICC/IF 50752-MCCHCD326 Ep-CAM, Ly74,, EGP314 10694-H02H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50591-M08H WB, ELISA, IHC-PCDw327 SIGLEC6, OB-BP1 12241-H02HCD331 FGFR1, Fms-like tyrosine kinase-2, KAL2, N-SAM 10616-H03H ELISA, IHC-P 50186-M02H ELISACD332 FGFR2, BEK, KGFR 10824-H03H ELISA 51128-M08H ELISACD333 FGFR3, ACH, CEK2 16044-H08H 50071-M03H ELISA

产品列表 (CD295-333)



13Name Alias Human protein Human antibody application Mouse protein Mouse antibody applicationCD334 FGFR4, JTK2, TKF 10538-H03H ELISA, IHC-P 50194-M08H ELISACD336 NKp44, Ly-95 homolog, NCR2 11550-H08HCD337 NKp30, Ly117, NCR3 10480-H03H ELISACDw338 ABCG2, BCRP, Bcrp1, MXR 11648-H02HCD339 Jagged-1, JAG1, JAGL1, hJ1 10004-H08H FCMCD340 ERBB2, MLN 19 10004-H08H WB, ELISA, IHC-P, FCM, ICC/IF, IP 50714-M08H WB, ELISACD344 Frizzled-4, Fz-4, FzE4 16137-H02HCD350 Frizzled-10, Fz-10, FZD10 16045-H08H 50568-M08HCD352 NTB-A, SLAMF6 11945-HCCH ELISA, IHC-P 50275-M08H ELISACD353 SLAMF8 50623-M08H WB, ELISA, IHC-PCD354 TREM-1 10511-H08H ELISACD355 CRTAM 11975-H08H ELISACD357 TNFRSF18 13643-H02HCD358 TNFRSF21 10175-H08H WB, ELISA 50263-M08H ELISACD360 IL-21R 11483-H08H ELISA 51184-M08HCD362 Syndecan-2, HSPG, SDC2 10355-H08H 51047-M05H

产品列表 (CD334-362)



14 药物靶点免疫治疗 - B7 家族蛋白

Fc 受体

配体其它名称种属功能受体其它名称种属B7.1 CD80 h, m, r, cy Co-stimulation CD28 h, m, r, cy

Co-inhibition CTLA-4 CD152 h, m, r, cy, caCo-inhibition B7-H1 PD-L1 h, m, r, cy, ca

B7.2 CD86 h, m, r, cy Co-stimulation CD28 h, m, r, cyCo-inhibition CTLA-4 CD152 h, m, r, cy, ca

B7-H1 PD-L1 h, m, r, cy, ca Co-inhibition PD-1 PDCD1 h, m, r, cy, caCo-inhibition B7.1 CD80 h, m, r, cy

B7-H2 ICOSL h, m, r, cy Co-stimulation ICOS CD278 h, m, rCo-stimulation CD28 h, m, r, cy

B7-H3 CD276 h, m, r, cy UnknownB7-H4 VTCN1 h, m, r UnknownB7-H5 VISTA h, m, r, rh Co-stimulation CD28H TMIGD2 hB7-H6 NCR3LG1 h, r, cy Co-stimulation NKp30 h, r, cyB7-H7 HHLA2 coming soon Co-stimulation CD28H TMIGD2 hB7-DC PD-L2 h, m, r, cy Co-inhibition PD-1 PDCD1 h, m, r, cy, ca

结合亚型分子名称其它名称种属生物素化蛋白结合亚型分子名称其它名称种属生物素化蛋白

IgG

FCGR1 CD64 h, m, r √ IgA FCAR CD89 h, rFCGR2A CD32a h, cy √

IgEFCER1A h, m

FCGR2B CD32b h, m, r, cy √ FCER2 CD23 h, m, rFCGR3A CD16a h, m (CD16), r √FCGR3B CD16b h, m (CD16-2) √FCGRT & B2M FcRn h, m, r, cy

*h: human; m: mouse; r: rat; cy: cynomolgus monkey; rh: rhesus monkey; ca: canine

*h: human; m: mouse; r: rat; cy: cynomolgus monkey


15药物靶点

其它常见药物靶点（选取部分）

免疫治疗 – TNF 超家族蛋白（选取部分）

分子名称种属活性分子名称种属活性CD20 h √ LAG3 h, m, rDPP4 h, m, cy √ NGF h, m √ERBB2 h, m, r, cy, rh, ca √ PCSK9 h, m, r, rh √ERBB3 h, m, r, rh √ VEGFA h, m, r, ca √HGF h, m, r, cy, ca √ VEGFR1 h, r √IL17A h, m, ca, ma √ VEGFR2 h, m, r √IL23 h, m, r, ma √ IGFBP3 h, cy √IL6R h, m, r, ca √ BTLA h, m, r, cy √LOXL2 h, m √ TIM3 h, m, cy

受体其它名称种属配体其它名称种属TNFRSF7 CD27 h, m, cy TNFSF7 CD70 h, rTNFRSF5 CD40 h, m, r, cy, ca TNFSF5 CD40LG h, m, r, cy, caTNFRSF9 CD137 h, m, ca TNFSF9 CD137L h, m, rTNFRSF4 OX40 h, m TNFSF4 OX40L h, cyTNFRSF13C BAFFR m, r TNFSF13B BAFF h, cy, ca

*h: human; m: mouse; r: rat; cy: cynomolgus monkey; ca: canine

*h: human; m: mouse; r: rat; cy: cynomolgus monkey; rh: rhesus monkey; ca: canine; ma: marmoset monkey


16 药物靶点文献例证使用义翘蛋白发表文献（选取部分）

蛋白产品文献名称杂志

PD-L1 HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients Cancer Res.

ICOS Vγ2Vδ2 T cell Costimulation Increases NK cell Killing of Monocyte-derived Dendritic Cells Immunology

CTLA4 Tumor-specific oncolytic adenoviruses expressing granulocyte macrophage colony-stimulating factor or anti-CTLA4 antibody for the treatment of cancers Cancer Gene Therapy

ERBB2 A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein-Receptor Complexes J. Am. Chem. Soc.

ERBB3 Development and characterization of small bispecific albumin-binding domains with high affinity for ErbB3 Cell. Mol. Life Sci.

PCSK9 Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes J. Biol. Chem.

VEGFR2 Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors Cell

IGFBP3 Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cells PLoS ONE

Fc receptors Enhanced potency of a fucose-free monoclonal antibody being developed as an Ebola virus immunoprotectant PNAS

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