skift typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient...
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Do self-rated and objective measures of cognitive impairment correlate in patients with work-related stress?
preliminary results and perspectives
Johan Høy Jensen a, Steffen Halmø Jonsson b, Jens Peter Bonde a, Jeanett Bauer b, Martin Balslev Jørgensen b, Kamilla Woznica Miskowiak b,c, Nanna Hurwitz Eller a
a Dept. Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg Hospital, Copenhagen, Denmark.b Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet Dept. 6233, Copenhagen, Denmark.c Dept. Psychology, University of Copenhagen, Copenhagen, Denmark.
Bispebjerg Hospital, University of CopenhagenDept. Occupational and Environmental Medicine
RESULTS AND DISCUSSIONWe found no significant association between cognitive complaintsand objectively measured cognitive impairment.
BACKGROUNDThere are indications that complaints about impaired cognition (impaired concentration and/or memory) are limiting return to work among long-term sick-listed patients with work-related stress. The literature supports the neuropsychological substrate of cognitive complaints with findings of impaired performance on cognitive tests.
It is recommended that cognitive impairments are considered when managing work-related stress, e.g., when advising the patient about the optimal time for return to work.
Assessment of cognitive impairment require time-consuming neuropsychological tests administered by a specialized psychologist, which is not routinely employed when managing patients with stress in the Danish occupational clinics. This pose a problem as it is unclear whether cognitive complaints properly reflectobjectively measured cognitive impairment.
AIMIn this ongoing study, we examine the associations between self-reported and objectively measured cognitive function in patients with work-related stress. In addition, we examine the associations between these cognition measures and baseline characteristics.
Self-reported cognitive complaints showed no correlation with objective cognitive function or number of months since diagnosis, but correlated with more subliminal depressive symptoms and more previous stress episodes. Thus, self-reported cognitive complaints seems to reflect psychological distress rather than de facto cognitive impairment.
In contrast, greater objective cognitive impairment was associated with poorer quality of sleep and fewer number of months since diagnosis, but not associated with number of previous stress episodes. Thus, objective cognitive impairment seems to be a better measure of the cognitive consequences of stress.
PERSPECTIVESThese preliminary findings point to a need for an easy-to-administer screening tool for objectively measured cognitive impairment in patients with work-related stress to better qualify the caregivers’ advice about the optimal time for return to work.
* p<0.05.
Contact: [email protected]
METHOD AND MATERIALS
Inclusion of participantsIn this ongoing study, 27 eligible-screened patients (74% females, n=20) aged 18-65 with work-related stress and no present/prior depression or severe somatic disease were assessed for self-rated and objectively measured cognitive function and baseline characteristics.
Screening for eligibility• Currently stressed (Karolinska Exhaustion Disorder Scale score >20)• No present (Major Depression Inventory total score <25) or prior
depression (Mini International Neuropsychiatric Interview)
Assessment tools• Baseline information: Age, sex, number of months since diagnosis,
number of previous episodes, and years of education.• Mass. Gen. Hosp.: Cognitive and Physical Functioning Questionnaire
(CPFQ): cognitive composite score of 4-items.• The Screen for Cognitive Impairment in Psychiatry (SCIP): Total score
of v. learning and recall, v. fluency, working memory, processing speed.• Hamilton Depression Rating Scale, 17-item (HDRS-17).• Non-restorative Sleep Scale (NSS), 9-item questionnaire.• Cohen’s Perceived Stress Scale (PSS), 10-item questionnaire.
Statistical analysesSpearman’s correlation analyses estimated the association between self-rated and objectively measured cognitive function. Spearman’s correlation analyses also estimated the associations between these cognition measures and baseline characteristics.
NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT, DENMARK
BACKGROUND AND AIM
Studies have indicated that long working hours are
associated with circulatory diseases.
The aim of the present studies was to test if long working
hours were prospectively associated with:
• ischaemic heart disease (IHD)
• usage of antihypertensive drugs (AD) or
• stroke – secondly haemorrhagic or ischaemic stroke
in a large randomly selected Danish cohort.
Long weekly working hours and risk of ischaemic
heart disease and stroke
(1) National Research Centre for the Working Environment, Copenhagen, Denmark; (2) Team Working Life, Copenhagen, Denmark; (3)
National Institute of Occupational Safety and Health, Berlin, Germany; (4) Lægekonsulenten.dk, Ballerup, Denmark; (5) Danish Centre of
Applied Social Science, Copenhagen, Denmark; (6) Department of Public Health, University of Copenhagen, Denmark.
Contact: [email protected]
Ann Dyreborg Larsen(1), Harald Hannerz (1), Karen Albertsen (2) Hermann Burr (3), Martin Lindhardt Nielsen (4), Jan
Hyld Pejtersen (5), Anne Helene Garde (1,6).
METHOD
Self-reported exposure from the Danish
Labour Force Survey (1999-2013) was
linked to national registers. Participants
were followed until becoming a case
(diagnose in health registers),
emigrated/dead due other causes or end of
study period (2014).
Poisson regression was used to analyse
the rate ratios as a function of working
hours. The analyses were adjusted for
calendar time, time since start of follow-up,
age, sex, SES, night and health care work
(the latter two for IHD only).
This work was funded by The Danish Work Environment Research Foundation
CONCLUSION
The analyses cannot confirm long
working hours to be associated with
IHD, AD or overall stroke. Data suggest
however, that long working hours might
be associated with increased rates of
haemorrhagic stroke.
RESULTS
Around 145,000 persons were
included with 3635 cases of
IHD, 20,648 cases of AD and
1737 cases of stroke. Trend test
for stroke showed that
estimated rate ratios per one
category increase in working
hours were 0.99 (0.93–1.06) for
overall stroke, 0.96 (0.88–1.05)
for ischaemic stroke and 1.15
(1.02–1.31) for haemorrhagic
stroke.
Rate ratios (RR) (95% CI) for IHD/AD as af function of working hours
Rate ratios (RR) (95% CI) for stroke as af function of working hours