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Page 1: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
Page 2: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require

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Do self-rated and objective measures of cognitive impairment correlate in patients with work-related stress?

preliminary results and perspectives

Johan Høy Jensen a, Steffen Halmø Jonsson b, Jens Peter Bonde a, Jeanett Bauer b, Martin Balslev Jørgensen b, Kamilla Woznica Miskowiak b,c, Nanna Hurwitz Eller a

a Dept. Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg Hospital, Copenhagen, Denmark.b Psychiatric Centre Copenhagen, Copenhagen University Hospital, Rigshospitalet Dept. 6233, Copenhagen, Denmark.c Dept. Psychology, University of Copenhagen, Copenhagen, Denmark.

Bispebjerg Hospital, University of CopenhagenDept. Occupational and Environmental Medicine

RESULTS AND DISCUSSIONWe found no significant association between cognitive complaintsand objectively measured cognitive impairment.

BACKGROUNDThere are indications that complaints about impaired cognition (impaired concentration and/or memory) are limiting return to work among long-term sick-listed patients with work-related stress. The literature supports the neuropsychological substrate of cognitive complaints with findings of impaired performance on cognitive tests.

It is recommended that cognitive impairments are considered when managing work-related stress, e.g., when advising the patient about the optimal time for return to work.

Assessment of cognitive impairment require time-consuming neuropsychological tests administered by a specialized psychologist, which is not routinely employed when managing patients with stress in the Danish occupational clinics. This pose a problem as it is unclear whether cognitive complaints properly reflectobjectively measured cognitive impairment.

AIMIn this ongoing study, we examine the associations between self-reported and objectively measured cognitive function in patients with work-related stress. In addition, we examine the associations between these cognition measures and baseline characteristics.

Self-reported cognitive complaints showed no correlation with objective cognitive function or number of months since diagnosis, but correlated with more subliminal depressive symptoms and more previous stress episodes. Thus, self-reported cognitive complaints seems to reflect psychological distress rather than de facto cognitive impairment.

In contrast, greater objective cognitive impairment was associated with poorer quality of sleep and fewer number of months since diagnosis, but not associated with number of previous stress episodes. Thus, objective cognitive impairment seems to be a better measure of the cognitive consequences of stress.

PERSPECTIVESThese preliminary findings point to a need for an easy-to-administer screening tool for objectively measured cognitive impairment in patients with work-related stress to better qualify the caregivers’ advice about the optimal time for return to work.

* p<0.05.

Contact: [email protected]

METHOD AND MATERIALS

Inclusion of participantsIn this ongoing study, 27 eligible-screened patients (74% females, n=20) aged 18-65 with work-related stress and no present/prior depression or severe somatic disease were assessed for self-rated and objectively measured cognitive function and baseline characteristics.

Screening for eligibility• Currently stressed (Karolinska Exhaustion Disorder Scale score >20)• No present (Major Depression Inventory total score <25) or prior

depression (Mini International Neuropsychiatric Interview)

Assessment tools• Baseline information: Age, sex, number of months since diagnosis,

number of previous episodes, and years of education.• Mass. Gen. Hosp.: Cognitive and Physical Functioning Questionnaire

(CPFQ): cognitive composite score of 4-items.• The Screen for Cognitive Impairment in Psychiatry (SCIP): Total score

of v. learning and recall, v. fluency, working memory, processing speed.• Hamilton Depression Rating Scale, 17-item (HDRS-17).• Non-restorative Sleep Scale (NSS), 9-item questionnaire.• Cohen’s Perceived Stress Scale (PSS), 10-item questionnaire.

Statistical analysesSpearman’s correlation analyses estimated the association between self-rated and objectively measured cognitive function. Spearman’s correlation analyses also estimated the associations between these cognition measures and baseline characteristics.

Page 3: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require

NATIONAL RESEARCH CENTRE FOR THE WORKING ENVIRONMENT, DENMARK

BACKGROUND AND AIM

Studies have indicated that long working hours are

associated with circulatory diseases.

The aim of the present studies was to test if long working

hours were prospectively associated with:

• ischaemic heart disease (IHD)

• usage of antihypertensive drugs (AD) or

• stroke – secondly haemorrhagic or ischaemic stroke

in a large randomly selected Danish cohort.

Long weekly working hours and risk of ischaemic

heart disease and stroke

(1) National Research Centre for the Working Environment, Copenhagen, Denmark; (2) Team Working Life, Copenhagen, Denmark; (3)

National Institute of Occupational Safety and Health, Berlin, Germany; (4) Lægekonsulenten.dk, Ballerup, Denmark; (5) Danish Centre of

Applied Social Science, Copenhagen, Denmark; (6) Department of Public Health, University of Copenhagen, Denmark.

Contact: [email protected]

Ann Dyreborg Larsen(1), Harald Hannerz (1), Karen Albertsen (2) Hermann Burr (3), Martin Lindhardt Nielsen (4), Jan

Hyld Pejtersen (5), Anne Helene Garde (1,6).

METHOD

Self-reported exposure from the Danish

Labour Force Survey (1999-2013) was

linked to national registers. Participants

were followed until becoming a case

(diagnose in health registers),

emigrated/dead due other causes or end of

study period (2014).

Poisson regression was used to analyse

the rate ratios as a function of working

hours. The analyses were adjusted for

calendar time, time since start of follow-up,

age, sex, SES, night and health care work

(the latter two for IHD only).

This work was funded by The Danish Work Environment Research Foundation

CONCLUSION

The analyses cannot confirm long

working hours to be associated with

IHD, AD or overall stroke. Data suggest

however, that long working hours might

be associated with increased rates of

haemorrhagic stroke.

RESULTS

Around 145,000 persons were

included with 3635 cases of

IHD, 20,648 cases of AD and

1737 cases of stroke. Trend test

for stroke showed that

estimated rate ratios per one

category increase in working

hours were 0.99 (0.93–1.06) for

overall stroke, 0.96 (0.88–1.05)

for ischaemic stroke and 1.15

(1.02–1.31) for haemorrhagic

stroke.

Rate ratios (RR) (95% CI) for IHD/AD as af function of working hours

Rate ratios (RR) (95% CI) for stroke as af function of working hours

Page 4: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
Page 5: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
Page 6: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
Page 7: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
Page 8: Skift Typografi - stressresearch.ku.dk · work - related stress, e.g., when advising the patient about the optimal time for return to work . ÙAssessment of cognitive impairment require
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