Pro:Typical papules with target featuresAcral distributionMucous membrane erosionsPrevious episodes

Con:Transient lesionsWidespread erythemaMacules and blisters, flat targetsSubacute evolution

Is it EM?

MAYBEYES NO

BopsyDirect IFSerum antibodies

UrticariaADR with some EM-like featuresAutoimmune blistersSJS

Is hospitalization needed?

YES

NO

What is the cause?

History of recurrent herpes

Cough, URT infection

Other patient infection, e.g., orf

No Clue

HAEM

Herpes serology

Idiopathic EM

MP-related EM Post-infection EM

Acyclovir prophylaxis

Possible HAEM

Azathioprine thalidomide

Frequent recurrent

Frequent recurrent

Positive

Negative