tara...med 2003, tahara-hanaoka, et al, blood 2006, nabekura et al, pnas 2010, okumura et al, j exp...
TRANSCRIPT
newsletter_vol5L i fe Sc ience Center for Surv iva l Dynamics ,
Tsukuba Advanced Research A l l iance (TARA)
Un ivers i ty o f Tsukuba
TA R A N E W S L E T T E R
h t t p s : / / w w w 1 . t a r a . t s u k u b a . a c . j p
No.5 October 2020
24
DNAM-1
30
Shibuya K. et al, Immunity 1999, Shibuya K, et al, J Exp
Med 2003, Tahara-Hanaoka, et al, Blood 2006, Nabekura et
al, PNAS 2010, Okumura et al, J Exp Med 2020, Nabekura
et al, Immunity 2020, DNAM-1
10
3
Log
DNAM-1 CD226
Fcα/μR CD351
Immunity Immunity J Exp Med J Exp Med J Clin Invest PNAS PNAS Immunity Immunity J Exp Med
1996 1999 2003 2008 2009 2010 2011 2014 2020 2020
2000 2009 2015 2016
2003 2011 2012 2014 2016
J Exp Med J Exp Med J Exp Med Nat Commun Nat Immunol
Nat Immunol 2010 J mmunol 2020
Science Immunol 2019
201910
Honda et al, PNAS 2009,
Honda et al, Nature Commun
2 0 1 620 0 3MAIR - ICD3 0 0 a,
MAIR-IICD300c Yotsumoto et al, J Exp Med
2 0 0 3
Nakano et al, J Exp Med 2011, Nakahashi-Oda, et al, J Exp
Med 2011, Nakahashi-Oda, et al, J Exp Med 2012, Totsuka et
al, Nature Commun 2014, Nakahashi-Oda, et al, Nature
Immunol 2016MAIR-I
Clec10a
Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex
1
PA-3LFN
d. IaNφ e. IaNφ
f
1 2 2
TARA NEWSLETTER October 2020 5
1 RNA 2025RNA
dap
DNA
DNASG2M
G1G2MG1SG2M
nanosnosNanos)
G1 NanosG1S
G1S
TARA NEWSLETTER October 20206
3
2
1
Myc plays an important role in Drosophila PM-hybrid dysgenesis to eliminate germline cells with genetic damage Myc PM
4
DNA
1.
2.
3.
5
Thbs1integrin αvβ1*4
GRap2YAP*5
Thbs1/integrin/YAP*6
Thbs1
2 YAP
Thbs1Thbs1KOYAP
TARA NEWSLETTER October 2020 9
The Corazonin-PTTH Neuronal Axis Controls Systemic Body Growth by Regulating Basal Ecdysteroid Biosynthesis in Drosophila melanogaster Crz-PTTH
6
Mike J. Pankratz
I-
“Structural basis for assembly and function of a diatom photosystem I-light harvesting supercomplex” I-FCP
7
I-
1
18 1000Nature Communications
Synergy between Sophorolipid Biosurfactant and SDS Increases Efficiency of P. aeruginosa Biofilm Disruption SDS
8
100
vi
B12
Z
SLx
SDSSLxSDS
2
9
1
Proceedings of the National Academy of
Sciences of the United States of America
1.
2.
3.
Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
10
5St3gal2St6gal1
Man1a
rHeltubarGal8N
11
3
1.
2.
3.
A
BsaA 20µm
25
Loss of PRMT1 in the CNS induces reactive astrocytes and microglia during postnatal brain development PRMT1
12
PRMT1
2
KO
MRC
TARA NEWSLETTER No.5
202010
h t t p s : / / w w w 1 . t a r a . t s u k u b a . a c . j p
20204 2
2020 Best Poster Award
1
2
3
2TARA
17
93
2020
Un ivers i ty o f Tsukuba
TA R A N E W S L E T T E R
h t t p s : / / w w w 1 . t a r a . t s u k u b a . a c . j p
No.5 October 2020
24
DNAM-1
30
Shibuya K. et al, Immunity 1999, Shibuya K, et al, J Exp
Med 2003, Tahara-Hanaoka, et al, Blood 2006, Nabekura et
al, PNAS 2010, Okumura et al, J Exp Med 2020, Nabekura
et al, Immunity 2020, DNAM-1
10
3
Log
DNAM-1 CD226
Fcα/μR CD351
Immunity Immunity J Exp Med J Exp Med J Clin Invest PNAS PNAS Immunity Immunity J Exp Med
1996 1999 2003 2008 2009 2010 2011 2014 2020 2020
2000 2009 2015 2016
2003 2011 2012 2014 2016
J Exp Med J Exp Med J Exp Med Nat Commun Nat Immunol
Nat Immunol 2010 J mmunol 2020
Science Immunol 2019
201910
Honda et al, PNAS 2009,
Honda et al, Nature Commun
2 0 1 620 0 3MAIR - ICD3 0 0 a,
MAIR-IICD300c Yotsumoto et al, J Exp Med
2 0 0 3
Nakano et al, J Exp Med 2011, Nakahashi-Oda, et al, J Exp
Med 2011, Nakahashi-Oda, et al, J Exp Med 2012, Totsuka et
al, Nature Commun 2014, Nakahashi-Oda, et al, Nature
Immunol 2016MAIR-I
Clec10a
Cryo-EM structures reveal translocational unfolding in the clostridial binary iota toxin complex
1
PA-3LFN
d. IaNφ e. IaNφ
f
1 2 2
TARA NEWSLETTER October 2020 5
1 RNA 2025RNA
dap
DNA
DNASG2M
G1G2MG1SG2M
nanosnosNanos)
G1 NanosG1S
G1S
TARA NEWSLETTER October 20206
3
2
1
Myc plays an important role in Drosophila PM-hybrid dysgenesis to eliminate germline cells with genetic damage Myc PM
4
DNA
1.
2.
3.
5
Thbs1integrin αvβ1*4
GRap2YAP*5
Thbs1/integrin/YAP*6
Thbs1
2 YAP
Thbs1Thbs1KOYAP
TARA NEWSLETTER October 2020 9
The Corazonin-PTTH Neuronal Axis Controls Systemic Body Growth by Regulating Basal Ecdysteroid Biosynthesis in Drosophila melanogaster Crz-PTTH
6
Mike J. Pankratz
I-
“Structural basis for assembly and function of a diatom photosystem I-light harvesting supercomplex” I-FCP
7
I-
1
18 1000Nature Communications
Synergy between Sophorolipid Biosurfactant and SDS Increases Efficiency of P. aeruginosa Biofilm Disruption SDS
8
100
vi
B12
Z
SLx
SDSSLxSDS
2
9
1
Proceedings of the National Academy of
Sciences of the United States of America
1.
2.
3.
Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging
10
5St3gal2St6gal1
Man1a
rHeltubarGal8N
11
3
1.
2.
3.
A
BsaA 20µm
25
Loss of PRMT1 in the CNS induces reactive astrocytes and microglia during postnatal brain development PRMT1
12
PRMT1
2
KO
MRC
TARA NEWSLETTER No.5
202010
h t t p s : / / w w w 1 . t a r a . t s u k u b a . a c . j p
20204 2
2020 Best Poster Award
1
2
3
2TARA
17
93
2020