test items for licensing examination krok 2 pharmacy · test items for licensing examination krok 2...

MINISTRY OF PUBLIC HEALTH OF UKRAINE

Department of human resources policy, education and science

Testing Board

Test items for licensing examination

Krok 2

PHARMACY

(російськомовний варіант)

Student ID Last name

Variant ________________

Authors of items: Andrieiev V.H., Arkhypova N.V., Baihush Yu.V., Bevz N.Yu., Belehay R.I.,

Beley N.M., Benzel L.V., Bieliaieva O.I., Bilous S.B., Bohdan N.S., Bokshan Ye.V.,

Bratenko M.K., Bushuieva I.V, Cherkovska L.H., Chornous V.O., Darmohray R.Ye., Dasiuk Ye.V.,

Denys A.I., Dorokhova L.P., Doroshkevych I.O., Dovzhuk V.V., Drachuk V.M., Dzviniatska O.F.,

Fizor N.S., Hadiak I.V., Haina Zh.M., Harna N.V., Hasiuk H.D., Herush O.V., Hladyshev V.V.,

Hlushachenko O.O., Hnidets V.I., Holod A.S., Holopykho L.I., Holovkin V.O., Horbata N.Yu.,

Horobynska S.M., Horoshko O.M., Hromovyk B.P., Hrozav A.M., Ivaniulyk I.I., Khmelova M.O.,

Klebansky Ye.O., Kornieva L.O., Korobko D.B., Korovenkova O.M., Kovalchuk T.S.,

Kovalenko S.I., Kraidashenko O.V., Kraievska Ye.V., Kryvoviaz O.V., Kucherenko N.V.,

Leleka M.V., Leonova S.H., Levchenko I.O., Levytska O.R., Liapunova O.O., Lopatynska O.I.,

Maksymchuk N.M., Marchyshyn S.M., Markiv I.M., Mazulin O.V., Muzyka N.Ya.,

Nedorezaniuk N.S., Nemchenko A.S., Nemiatykh O.D., Ohar S.V., Ohdansky K.M., Okkert I.L.,

Palamar A.O., Panfilova H.L., Perederiy Ye.O., Peresekina N.M., Podpletnia O.A., Poliak O.B.,

Popova N.V., Popovych V.P., Romanyshyn N.M., Rykhlitska K.V., Sakhatska I.M., Sasko O.V.,

Shanaida M.I., Sikoryn U.B., Sincha N.I., Skrylova N.M., Skupa O.O., Soboleva V.O.,

Sokolova L.V., Stadniychuk R.F., Sterioni I.V., Taller O.Yu., Tereshchuk S.I., Ternynko I.I.,

Tkachenko O.P., Tkachenko V.H., Trofimova T.S., Tsveiuk N.P., Tykhonov O.I., Tykhonova S.O.,

Tymchenko A.Yu., Upyr L.V., Vashchenko K.F., Vidavska A.H., Vynnyk I.O., Yakovleva O.O.,

Yehorov I.A, Yeromina Z.H., Yevtushenko I.S, Zamorsky I.I., Zaruma L.Ie., Zeleniuk V.H.,

Zhyvora N.V., Zub L.O. and Committees of professional expertise.

Item reviewers: Burian H.O., Darmograi R.Ye., Hala L.O., Holopykho L.I., Hrytsenko B.I.,

Khokhlenkova N.V., Korobko D.B., Koval A.Ya., Kovalska N.P., Lenchyk L.V., Lesyk R.B.,

Levytska O.R., Marchyshyn S.M., Moriak Z.B., Nazarkina B.M., Nemiatykh O.D., Otrishko I.A.,

Pukhalska I.O., Samohalska O.Ye., Unhurian L.M., Vashchenko K.F., Voitenko L.P., Zhadko S.V.

The book includes test items for use at licensing integrated examination “Krok 2 Pharmacy” and

further use in teaching.

The book has been developed for students of pharmaceutical faculties and academic staff of higher

medical educational establishments.

Approved by Ministry of Public Health of Ukraine as examination and teaching

publication based on expert conclusions (Orders of MPH of Ukraine of 14.08.1998 №251,

of 27.12.1999 №303, of 16.10.2002 №374, of 16.04.2003 № 239, of 29.05.2003 №233).

© Copyright Testing Board.

General Instruction

Every one of these numbered questions or unfinished statements in

this chapter corresponds to answers or statements endings. Choose the

answer (finished statements) that fits best and fill in the circle with the

corresponding Latin letter on the answer sheet.

Кrok 2 Pharmacy (англомовнi студенти) 2016 рiк 1

1. A pharmacist prepares powderswith a substance hard to comminute.What substance should be commi-nuted with a volatile liquid?

A. CamphorB. Magnesium oxideC. Zinc sulfateD. Copper sulfateE. Glucose

2. A pharmacist has preparedpowders including extract ofbelladonna in the amount of 0,015per dose. For ten doses he had to takethe following amount of dry extract:

A. 0,3 gB. 0,15 gC. 1,5 gD. 0,03 gE. 0,015 g

3. A pharmacy has prepared a soluti-on of macromolecular substance wi-th limited swelling capacity. Whatsolution was labelled ”warm upbefore use”?

A. GelatinB. TrypsinC. PepsinD. Methyl celluloseE. Pancreatin

4. A dispensing chemist canrecommend a drug made fromseeds of Aesculus hippocastanum tobe taken as a veintonic and anti-thrombotic agent to treat venouscongestion and veins dilatation oflower extremities. This drug is:

A. AescusanB. PhytolysinC. FlaminD. MarelinE. Ajmaline

5. A pharmacy prepares drugs byindividual prescriptions. How oftenshould the floors be mopped down inthe prescription department?

A. Once in a shiftB. Once in a weekC. Once every 10 daysD. Once every 5 daysE. Once every 3 days

6. Schedule of sanitation actionsin pharmacies is regulated by therelevant regulatory acts. Cleaningday at a pharmacy must be scheduledfor at least 1 time:

A. In a monthB. In a weekC. In 3 daysD. In 10 daysE. In 5 days

7. A pharmaceutical companyfocuses on selling a diverse range ofproducts covering different customergroups and regions. What kind oforganizational structure is typical forsuch company?

A. DivisionalB. BureaucraticC. FunctionalD. CentralizedE. Decentralized

8. A pharmaceutical companyproduces cordiamin solution. Duri-ng the quality control its quantitati-ve content was determined by meansof refractometry. For this purpose ananalytical chemist measured:

A. Index of refractionB. ViscosityC. DensityD. Intensity of absorptionE. Angle of rotation

9. Specify which of the alkaloids gi-ven below will react positively toxanthines (murexide test):

A. CaffeineB. Atropine sulfateC. Papaverine hydrochlorideD. Quinine sulfateE. Ephedrine hydrochloride

10. Which of the following drugs isused for thrombolytic therapy in case


of myocardial infarction?

A. StreptokinaseB. HeparinC. PhenylinumD. TiclopidineE. Acetylsalicylic acid

11. A patient, who had a case ofcardiac infarction, is recommendedto take acetylsalicylic acid to:

A. Decrease thrombocyte aggregati-onB. Decrease body temperatureC. Dilate coronary vesselsD. Decrease inflammationE. Lower cholesterol rate

12. Stinging nettle (Urtica dioi-ca) leaves are mostly used as ahemostatic in tinctures and liquidextracts to treat lung, intestinal, anduterine hemorrhages. What bioacti-ve substance provides hemostaticeffect?

A. Vitamin KB. β-caroteneC. RutinD. ReserpineE. Digitoxin

13. What herbal bioactive substancesyield a positive reaction with ferricammonium alum solution?

A. TanninsB. SaponinsC. PolysaccharidesD. BittersE. Fatty oils

14. Cumulating drugs - Digitoxinand Соrdigitum - are used to treatchronic cardiac insufficiency. Whatplant is used as the raw material inproduction of these drugs?

A. Digitalis purpureaB. Strophanthus kombeC. Adonis vernalisD. Convallaria majalisE. Erysimum canescens

15. To prepare a syrup the followi-

ng ingredients are taken: 82 parts ofsugar syrup, 1 part of KJ (KBr),12 parts of liquid thyme extract and5 parts of 96% ethanol. Name thisdrug:

A. PertussinB. CholosasC. AmbroxolD. BroncholytinE. Licorice syrup

16. A pharmaceutical enterprise thathas achieved high sales rates andcustomers’ recognition will reach thehighest profit at the following stageof the product life cycle:

A. MaturityB. Market penetrationC. GrowthD. DecreaseE. Development

17. A marketing specialist of a retailpharmacy analyzes price lists ofwholesale firms and manufacturers.The key factor in the choice of asupplier is:

A. Selection-price characteristics ofproductionB. Production multifunctionalityC. Post-sale service qualityD. Supply volumeE. Market conditions

18. Suspension workshop introducesproduction of new drugs. Specifythe optimal approach to suspensionproduction:

A. Grinding in a liquid mediumB. Drop methodC. RepercolationD. PercolationE. Maceration

19. Aerosol workshop of apharmaceutical plant uses propellantsof different groups. What propellantsbelong to the group of compressedgases?


A. Nitrogen, nitrous oxide, carbondioxideB. FreonsC. Propane, butane, isobutaneD. Vinyl and methyl chlorideE. Methylene chloride, ethylenechloride

20. An analytical chemist confirmsthe presence of calcium ions in calci-um lactate molecule by means ofreaction with ammonium oxalate.The reaction occurs in the mediumof:

A. Acetic acidB. AmmoniaC. Sodium hydroxideD. FormaldehydeE. Potassium chloride

21. A pharmacist has usedcondensation method to prepare asuspension. Select the substancesthat make up the precipitate:

A. Calcium chloride with sodiumhydrocarbonateB. Caffeine and sodium benzoatewith zinc oxideC. Sodium bromide with camphorD. Potassium bromide with sodiumbenzoateE. Magnesium sulfate with potassiumiodide

22. A pharmacy received aformula for an extemporaneouslycompounded medication. Specify thedocument that is used to set the pricefor such medication:

A. Retail price list for drugsB. Inventory reportC. Certificate of qualityD. Cash receipt voucherE. Certificate of analysis

23. A pharmacist has madepolyethylene oxide-based supposi-tories with Streptocid. Specify theapproach to introducing the activeingredient into the vehicle:

A. Dissolution in the molten vehicleB. Emulsification and blending withthe vehicleC. Trituration with small amount ofwaterD. Suspending in the vehicleE. Blending with vaseline oil

24. Preparations from Althaea offi-cinalis roots are used for treatmentof upper airways conditions. Duringharvesting this herbal raw materialthe following can become an admi-xture:

A. Lavatera thuringiacaB. Plantago majorC. Tanacetum vulgareD. Cichorium intybusE. Taraxacum officinale

25. A Ukrainian pharmaceuticalcompany established a subsidiarycompany abroad. What organisati-onal form of international business isit?

A. Direct possessionB. Direct exportC. LicensingD. Contractual production of drugsE. Joint venture

26. What product strategy ischaracterized by introducing to themarket a product designed for thelargest market segments and maxi-mal amount of customers?

A. Undifferentiated marketingB. Differentiated marketingC. Concentrated marketingD. DiversificationE. Variation

27. Which of the following anti-hypertensive drugs has potassium-sparing action?

A. TriamtereneB. FurosemideC. PrazosinD. MetoprololE. Diltiazem

28. An essential oil is a component of


such compound drugs as: Inhalypt,Corvalol, Pinosol, Corvaldin, toothdrops. What herbal raw material isthe source of this essential oil?

A. Folia Menthae piperitaeB. Folia BetulaeC. Folia UrticaeD. Folia AgavaeE. Folia Absinthii

29. A pharmacist has been on a busi-ness trip. What is the deadline forsubmitting a travel expense report?

A. Three working days after returningfrom a tripB. Four working days after returningfrom a tripC. Ten working days after returningfrom a tripD. A week after returning from a tripE. There is no deadline

30. A pharmacy prepares atropinesulfate trituration. What adjuvantshould be used to prepare this tri-turation?

A. LactoseB. SaccharoseC. GlucoseD. StarchE. Talcum

31. To prepare a suspension a medi-cinal substance should be trituratedwith a small amount of liquid. Specifythe optimal amount of liquid for tri-turation of 10 g of zinc oxide accordi-ng to the Deryagin’s rule:

A. 5 mlB. 10 mlC. 2 mlD. 1 mlE. 0,5 ml

32. A pharmaceutical factoryproduces tablets of sodium chloride.What is the method of their producti-on?

A. Direct compression without addi-tional substancesB. MouldingC. Direct compression with the addi-tion of adjuvantsD. Wet granulation prior tocompressionE. Dry granulation prior tocompression

33. Various types of dryers can beused for granule dehumidification.Specify the type of ”СП-30” dryer:

A. Fluidized bed dryerB. Freeze dryerC. Infrared dryerD. Silica gel dryerE. Forced air dryer

34. Ampoule workshop of a factoryproduces injection solution. Namethe stabilizer to be added to 1%morphine hydrochloride injectionsolution:

A. 0,1 N solution of hydrochloric acidB. 0,1 N solution of sodium chlorideC. Amino-propylene-glycolD. RongaliteE. Sodium metabisulfite

35. An analyst of a chemicallaboratory obtained a glucosesubstance for analysis. To check itsquality he used a polarimeter. Theanalyst measured:

A. Angle of rotationB. Refractive indexC. Optical densityD. Melting pointE. Specific gravity

36. Rhamnus cathartica herbal rawmaterial can be used as a laxative.What plant parts are harvested fordrug producton?

A. FruitB. LeavesC. BarkD. RootsE. Sprouts

37. Crude drugs CANNOT be tasted


if they contain:

A. ToxinsB. Essential oilsC. PolysaccharidesD. Bitter glycosidesE. Vitamins

38. During microscopy of Althaearoot it is necessary to determine thepresence of starch granules withinthe plant cells. What reagent enablessuch analysis?

A. Lugol’s solutionB. Ammonium hydroxideC. Concentrated sulfuric acidD. Alcohol solution of α-naphtholE. Thymol solution

39. Collective labour agreement isconcluded by a trade union commi-ttee with the enterprise owner onbehalf of the workforce. Any collecti-ve agreement is worked out in wri-tten form. Which article of the LaborCode regulates the duration of thecollective agreement?

A. 17B. 36C. 38D. 40E. 41

40. For the purpose of sales sti-mulation a pharmaceutical wholesalecompany grants its customers adiscount according to the socialcontract and on condition of theirloyalty. Specify the type of discount:

A. BonusB. DealerC. SeasonalD. Discounts for quantity ofpurchased goodsE. -

41. Before goods are accepted by apharmacy, they should be checkedfor quantity and quality. If there isno discrepancy, the pharmacy issuesa warrant for receipt of goods. Thiswarrant is valid for:

A. 10 daysB. 3 monthsC. 1 yearD. 15 daysE. 20 days

42. Companies producing injectabledosage forms apply differentmethods of ampoule sealing. Sealingagainst a jet of inert gases (nitrogen,argon, carbon dioxide) is suitable forthe following injection solutions:

A. Easily oxidableB. ViscousC. ThermostableD. Hydrolytically unstableE. Photosensitive

43. An analytical chemist of a centralindustrial laboratory performsquantitative determination of peni-cillin sum in benzylpenicillin sodiumsalt by means of iodometric method.What indicator is used?

A. StarchB. PhenolphthaleinC. Potassium chromateD. Methyl orangeE. Methyl red

44. A pharmacist prepares cocoabutter-based round vaginal supposi-tories with less than 5% of citric acid.Specify the most rational approach tointroduction of the active ingredientinto the vehicle:

A. Dissolve in minmal quantity ofpurified waterB. Dissolve in Dimexid (Di-methylsulfoxide)C. Dissolve in molten cocoa butterD. Dissolve in vaseline oilE. Dissolve in alcohol

45. Suppositories are prepared byvarious methods such as rolling,pouring, pressing. What base is usedin the pouring method?


A. ButyrolumB. ParaffinC. Cocoa butterD. VaselineE. Coriander oil

46. A pharmacist has made an injecti-on solution with 0,1 M of sodiumhydroxide solution as a stabilizer.What substance requires such stabili-zer?

A. Caffeine and sodium benzoateB. Dibazol (Bendazol)C. Sodium hydrocarbonateD. Sodium chlorideE. Glucose

47. Anesthesin is a substance withlocal anesthetic activity and a deri-vative of the following acid:

A. Para-aminobenzoicB. Para-aminosalicylicC. Para-aminobenzolsulfonicD. Para-chlorbenzoicE. Para-aminophthalic

48. Paracetamol substance has beenreceived for analysis. Reaction wi-th the solution of iron (III) chlori-de resulted in blue-purple color. Thisindicates the presence of:

A. Phenolic hydroxylB. Aldehyde groupC. Keto groupD. Ester groupE. Alcoholic hydroxyl

49. Production of tablets requiresstage-to-stage quality control. Whatdevices are used to determine theparticle size distribution (fraction) ofgranules?

A. Standard set of sievesB. Various vibrosievesC. Blade friabilatorsD. Laboratory identifiersE. Microscope

50. Various dryer types are used inproduction of herbal and animal-derived drugs. What dryer wouldbe optimal for dehumidification of

thermolabile compounds?

A. Freeze dryerB. Roller dryerC. Band dryerD. Drying ovenE. Drum dryer

51. An analytical laboratory hasreceived a procaine hydrochloridesubstance for analysis. According tothe State Pharmacopoeia of Ukrainelimit content of heavy metals shouldbe determined with the followingreagent:

A. ThioacetamideB. Methoxyphenylacetic acidC. HypophosphiteD. Aminomethyl alizarin acetic acidE. Sulfomolybdenum

52. Select a reagent that should beapplied by an analytical chemist todetect alkaloids in the herbal rawmaterial:

A. Dragendorff reagentB. Bromine waterC. Alkaline solutionD. Stahl’s reagentE. Trim-Hill reagent

53. A warehouse received a batchof herbal raw material consistingof peppermint leaves. Specify thestorage conditions for this herbalmaterial:

A. Separately from other herbal rawmaterialsB. Under the regular conditionsC. In metal storage containersD. Protected against CO2E. At the temperature of -5oC

54. For a month a pharmacy hasbeen receiving multiple deliveriesfrom various suppliers. What accrualdocument is used to record the goodsreceived by the pharmacy?


A. Merchandise activity reportB. Invoice registerC. Receipt log bookD. Cash bookE. Debit/credit invoice

55. A set of values, traditions, behavi-oral norms and views inherent to anorganisation characterize its followi-ng feature:

A. CultureB. SuccessC. ProfitabilityD. Capitalization levelE. Self-development capability

56. Products differentiation (advantages)pursued by a pharmaceuticalcompany with the aim to surpass itscompetitors in satisfying customers’sdemands is called:

A. Product leadershipB. BenchmarkingC. Porter’s generic strategies modelD. Penetration strategyE. Concentration strategy

57. Sterilization methods used for thepreparation of drugs under asepticconditions can be differentiated intophysical, mechanical, and chemicalones. Specify the chemical method ofsterilization:

A. Addition of preservativesB. Dry heat sterilizationC. Radiation sterilizationD. Pressure steam sterilizationE. UV light sterilization

58. One of the first stages of busi-ness activity is to register an enterpri-se with public authorities. Whatdocuments NEED NOT be submi-tted to the local authorities for stateregistration of an enterprise?

A. Samples of director’s and chiefaccountant’s signaturesB. Record cardC. Payment document for registrationfeeD. Payment document confirmingowner’s assessed contributionE. Constituent documents

59. For better coverage of variousmarkets the Lubnyfarm companysells a portion of its productionthrough its chain of pharmacies,another portion is being sold throughdistributors, and the third - throughpharmacies of another owners. Whatmarketing system of distribution isused by this company?

A. MultichannelB. HorizontalC. CorporateD. ContractualE. Administered

60. One of the most importantmarket characteristics is a goodseconomic trend. What economictrend can be characterized by relati-ve stability of high prices and the hi-ghest activity of manufacturers andcustomers?

A. High (stable)B. SubsidingC. DownwardD. SluggishE. Low

61. A patient has been administeredpowders containing menthol. What isthe best way to achieve the requiredextent of menthol comminution?

A. To triturate it with alcohol or etherB. To triturate it with glycerine orchloroformC. To triturate it with purified waterD. To triturate it with othercomponents of the formulaE. To triturate it thoroughly withsugar

62. An analytical laboratory receiveda sample of alpha-aminobutyric acidfor analysis. What reagent should


be used by the analytical chemist toidentify this substance?

A. NinhydrinB. Sodium nitrateC. BenzeneD. AnilineE. Calcium bromide

63. A retail pharmacy has beenpurchasing goods within an accounti-ng period. What changes to thebalance will result from this businesstransactions?

A. Increase in assets and liabilitiesB. Decrease in assets and liabilitiesC. Changes will affect only the assetsD. Changes will affect only the liabili-tiesE. -

64. Which of the following non-steroid anti-inflammatory agentshas the least harmful effect on themucosa of gastrointestinal tract?

A. NimesulideB. DiclofenacC. IndomethacinD. PiroxicamE. Acetylsalicylic acid

65. When preparing an ointment wi-th castor oil and vaseline a pharmaci-st failed to obtain a homogeneoussystem. What is the most likely causeof incompatibility between thesecomponents?

A. Immiscibility of the ingredientsB. Limited solubilityC. Release of crystallization waterD. CoagulationE. Adsorption

66. Tablet quality is assessedthrough various indicators. Name theapparatuses used to measure tabletdissolution:

A. Paddle, flow-through cellB. Rotating basket, flow-through cellC. Paddle, rotating basketD. Flow-through cellE. Rotating basket

67. When doing calculations todetermine the limit of the cashbalance, an accountant must speci-fy the actual amount of cash receipts.What time period should be takeninto account?

A. Three months prior to calculationB. Six months prior to calculationC. 1 year prior to calculationD. 10 days prior to calculationE. 7 days prior to calculation

68. A certain plant is used forproduction of tinctures and extractsthat are a part of complex drugs, suchas Bellataminal, Becarbon, Besalol,etc. Specify the grass that is used forthis purpose:

A. BelladonnaB. Lily of the valleyC. AstragalusD. BeggarticksE. Celandine

69. A pharmacist has prepared a drugby the following prescription:Rp.: Streptocidi

Dermatoli ana 1,0LanoliniVaselini ana 5,0M.D.S.: Apply to the affected area of skin.

Specify the type of the dispersesystem:

A. Suspension ointmentB. Solution ointmentC. Hydrophilic ointmentD. Combined ointmentE. Extraction ointment

70. Which of the following antibioticscan be identified by means of maltoltest?


A. Streptomycin sulfateB. Doxycycline hydrochlorideC. AmoxicillinD. Lincomycin hydrochlorideE. Kanamycin monosulfate

71. What concept can be describedas determining the goods specificati-ons, special features that distinguishthese goods from their competitor-manufactured analogues?

A. PositioningB. SelectionC. QualityD. DemandE. Consumer value

72. Aerosols contain active ingredi-ents, solvents, propellants. Whatsubstances can be used aspropellants?

A. Freon 11, carbon monoxide,propane/butane mixtureB. Isopropyl myristate, neon, sulfuroxideC. Glycerine, argon, heliumD. Linaetholum, myristinic acid,benzocaineE. Hydrogen sulfide, hydrogen, tri-ethanolamine

73. White precipitate producedby the reaction of morphinehydrochloride with ammonia soluti-on dissolves in sodium hydroxidesolution due to the presence of thefollowing group in the structure ofmorphine hydrochloride:

A. Phenolic hydroxylB. Carboxyl groupC. Aldehyde groupD. Alcoholic hydroxylE. Keto group

74. A pharmacy plans to purchaseand retail goods of different stockrecord units. Which group of goodsdoes VAT reduction apply to?

A. MedicamentsB. Baby foodC. OpticsD. Curative cosmeticsE. Perfumes

75. During processing, drying andrefinement of herbal raw materialscontaining saponins the dust parti-cles can cause mucosa irritation.Therefore, precautionary measuresshould be observed when workingwith:

A. Rhizoma et radices PolemoniiB. Rhizomata TormentillaeC. Radices AraliaeD. Rhizomata BistortaeE. Rhizomata et radices Rubiae

76. An analytical chemist identifiesthe substance of potassium acetate.What reagent confirms the presenceof potassium cation in the substance?

A. Tartaric acidB. Sodium hydroxideC. Potassium permanganateD. Iron (III) chlorideE. Zinc oxide

77. A pharmacy has received a batchof drugs from a pharmacy depot.Specify the drug subject to thecontrolled substance inventory inpharmacies:

A. DicaineB. ParacetamolC. AnalginD. NovocaineE. Acetylsalicylic acid

78. A pharmaceutical companyconducted an age-specific segmentanalysis of the regional antihistaminemarket. It revealed the lack of antihi-stamines for children. The companywill consider this segment as:


A. A market nicheB. An unattractive segmentC. A market shareD. A segment requiring furtherresearchE. A market door

79. The manufacturing pharmaceuti-cal company ”Elema” has set upits own corporate pharmacy. In thiscase, it uses the following distributi-on channel:

A. Zero levelB. First levelC. Second levelD. Third levelE. Fourth level

80. What type of market can becharacterized by the following condi-tions: there are many sellers andbuyers, who have no influenceover current prices; similar andinterchangeable competing goodsare available; no price limits?

A. Pure competitionB. Monopolistic competitionC. OligopolyD. Pure monopolyE. Economic planning

81. An analytical laboratory recei-ved the task to confirm the presenceof ethylenediamine in aminophylli-ne. Which of the following reagentsallows to detect ethylenediamine?

A. Copper (II) sulfateB. Sodium hydroxideC. Concentrated sulfuric acidD. Silver nitrateE. Barium chloride

82. Specify the indicator thatmeasures the total contributionof various solutes to the osmoticpressure of the solution:

A. OsmolalityB. IsohydricityC. IsotonicityD. IsoviscosityE. Apyrogenicity

83. Quality of viscous extracts isassessed based on a variety of indi-ces. Specify the maximum allowedmoisture content of viscous extractsaccording to the regulations of theState Pharmacopoeia of Ukraine:

A. 30%B. 20%C. 10%D. 5%E. 100%

84. Injection solutions in ampoulesare assessed through various indi-cators. What percentage of ampoulesshould be checked for mechanicalimpurities?

A. 100%B. 98%C. 95%D. 90%E. 50%

85. A pharmacy prepares suspensi-ons. What substance can be used forpreparing a suspension without addi-ng a stabilizer?

A. Magnesium oxideB. CamphorC. SulfurD. MentholE. Phenyl salycylate

86. During planned inventory of cashmoney in a pharmacy cash registerthere is an unaccounted surplus di-scovered. What should a committeedo with this surplus?

A. Record as receivedB. Transfer to authorized capitalC. Transfer to accounts payableD. Transfer to accounts receivableE. Transfer to emergency fund

87. To confirm the presence of sulfations in the medicinal preparationof magnesium sulfate an analyti-cal chemist of a pharmacy uses thefollowing solutions:


A. Barium chloride and hydrochloricacidB. Ammonium chloride and ammoni-um hydrateC. Silver nitrate and nitric acidD. Benzenesulfonic acidE. Diphenylamine

88. Streptocide, sulfacyl sodium,norsulfazole or sulfadimezinum canbe identified by means of the reacti-on that forms:

A. Azo dyeB. MurexideC. IodoformD. FluoresceinE. -

89. Pharmaceutical market is in sucha situation when there is only onecompany selling a certain product.Specify the competitive structure ofthe market:

A. Pure monopoly marketB. Pure competition marketC. Monopolistic competitive marketD. Oligopolistic marketE. Pure monopoly market and oli-gopolistic market

90. A pharmaceutical company hasmade a decision to expand its activiti-es. The process of the company’s acti-vity expansion by penetration intonew fields of the branch is called:

A. DiversificationB. SegmentationC. ConglomerationD. IntegrationE. Centralization

91. An analytical chemist determinesthe quantity of a drug by the methodof indirect bromatometry. Which ofthe following titrated solutions is tobe used?

A. Sodium thiosulfateB. Calcium bromateC. Sodium edetateD. Sodium nitriteE. Silver nitrate

92. A pharmacist working at ananalytical laboratory is performingsulfite-ion identification of a drug incompliance with the requirementsof State Pharmacopoeia of Ukraine.What reagent becomes colorless inthis investigation?

A. Iodine solutionB. Iron (III) chloride solutionC. Ammonia solutionD. Potassium iodide solutionE. Potassium nitrate solution

93. An analytic laboratory received”Aether anaestheticus” for analysis.Which reagent should be used fordetection of acetone and aldehydeadmixtures according to the StatePharmacopoeia of Ukraine?

A. Alkaline solution of potassiumtetraiodomercurateB. Ammonium solution of argentumnitrateC. Aqueous solution of potassiumiodideD. Sodium hydrosulphiteE. Hydroxylamine solution

94. Natural persons registered assmall business entities with simpli-fied taxation scheme (2 group) aresubject to the limit of the annualamount of sales proceeds. Specify theproceeds limit:

A. 1 million UAHB. 750 thousand UAHC. 100 thousand UAHD. 3 million UAHE. 5 million UAH

95. Fatty oil containing unsaturatedfatty acids is used for the preventionof atherosclerosis. Specify the herbalraw material used in oil production:

A. Seeds of flaxB. Seeds of fennelflowerC. Fruits of dillD. Fruits of black chokeberryE. Hawthorn berries

96. Quality of dried extracts isassessed according to several cri-


teria. Specify the highest acceptableamount of moisture in driedextracts according to the StatePharmacopoeia of Ukraine:

A. 5%B. 25%C. 20%D. 75%E. 95%

97. When preparing dermatologicalointments the following substanceshould be introduced by suspending:

A. XeroformB. CamphorC. MentholD. Protargol (silver proteinate)E. Ephedrine hydrochloride

98. Benzathine benzylpenicillin is thedrug of choice for treatment of thefollowing disease:

A. SyphilisB. Intestinal infectionC. PneumoniaD. TonsillitisE. Furunculosis

99. The main active substances ofsenna leaves and fruits are sennosi-des A, B, C, D. They belong to thefollowing class of biologically activesubstances:

A. Anthracene derivativesB. Phenolic acidsC. FlavonoidsD. IridoidsE. Thioglycosides

100. Codeine is used as a cough-depressant. What herbal raw materi-al contains this alkaloid?

A. Pods of opium poppyB. Pods of plume poppyC. Celandine grassD. Grass of common periwinkleE. Tea leaves

101. What herbal drug producedform alkaloid-containing raw materi-als can be recommended for

neurasthenia, insomnia, menopausaldisorders?

A. NovopassitB. ErgotamineC. Glaucine hydrochlorideD. Securinine nitrateE. Vinblastine

102. A pharmacist prepares 3000 mlof valerian root infusion for a hospi-tal department. The given amount ofextract should be infused in a waterbath for:

A. 25 minutesB. 45 minutesC. 15 minutesD. 10 minutesE. 30 minutes

103. A pharmacist has prepared asolution of menthol oil. Specify thedissolution temperature of the activesubstance:

A. 40-50oCB. 60-70oCC. 30-40oCD. 70-80oCE. 20-30oC

104. The risk can arise from someforms of activity connected wi-th production of goods and servi-ces, their selling, commodity-moneyand financial operations, commerce,implementation of socioeconomicand scientific-and-technical projects.This is the definition of the followingconcept:

A. Business riskB. Loss of propertyC. Labour lossD. Loss of timeE. Financial loss

105. Althaea roots are used as amucolytic agent. Underground partsof this plant are harvested:


A. After the seeds have ripened, andthe above-ground part have died offB. In the period of blossomingC. In the period of fruitingD. In the period of buddingE. In the period of stem extension

106. Substance of calcium pangamateis to be studied in an analyticallaboratory. Calcium cations formwhite precipitate with the followingreagent:

A. Ammonium oxalateB. Sodium chlorideC. Potassium permanganateD. Potassium bromideE. Sodium cobaltinitrite

107. In cases of inorganic mercurycompounds poisoning the followingdrug should be used for antidotaltherapy:

A. Unithiol (Dimercaptopropanesulfonate)B. NaloxoneC. Calcium tetacineD. Desferal (Deferoxamine)E. Dexamethasone

108. As a pharmacist was serving acustomer, who ordered a nonprecri-ption drug, he realized that the pati-ent did not apprehend the verbalinformation. Name the communicati-ve barriers that arise when words orsymbols may have different meani-ngs for the information sender andthe receiver:

A. Semantic barriersB. Neglect of factsC. Nonverbal barriersD. Failure to understand theimportance of informationE. Stereotypes of thinking

109. Tyndallization is used at apharmaceutical factory as one ofsterilization methods for thermolabi-le substances. What is the essence ofthis method?

A. Triple heating of solution to 40-60oC with 24-hour-long intervals inbetween for thermostatingB. Autoclaving at 119-121oC withpressure at 1,0-1,1 atmC. Sterilization with flowing steam at100oCD. Sterilization with dry heat at 180-200oC for a lengthy period of timeE. Sterilization with high-frequencyand microwave frequency current

110. What final document is used forthe preparation of the report on thediscrepancies revealed in the courseof the inventory at a pharmacy?

A. Act on the inventory resultsB. Inventory item descriptionC. ChecklistD. Commercial reportE. Invoice

111. According to the basic regulati-ons for supply of medical products,pharmacies should be supplied withmedicaments that have a remainingshelf life of no less than . . .%, andbacterial preparations of no less than. . .%:

A. 60%, 40%B. 80%, 60%C. 50%, 40%D. 40%, 20%E. 60%, 30%

112. A pharmaceutical enterpriseproduces ointments. What base isused for production of sulfur oi-ntment simple?

A. EmulsionB. VaselineC. Base ”For ophthalmic ointments”D. LanolinE. Polyethylene glycol

113. Powders that quickly enter intoa reaction in presence of water andemit carbon dioxide belong to thefollowing group:


A. Effervescent powderB. Soluble powderC. Powders for oral useD. Nasal powdersE. Powders for external use

114. While filling hard gelatincapsules such glidants as 0,1% - 0,3%aerosil or magnesium stearate alongwith 0,5% - 1% talcum are oftenadded to the filling agent in order toimprove the following properties:

A. FlowabilityB. HomogeneityC. Regulation of moisture contentD. Homogeneity of mixingE. Ability to contact molding

115. A patient suffering frombronchial asthma has been diagnosedwith essential hypertension. Whatantihypertensive drug is contraindi-cated in this case?

A. PropranololB. CaptoprilC. AmlodipineD. Hypothiazid (Hydrochlorothiazi-de)E. Verapamil

116. A female patient in the first tri-mester of her pregnancy has been di-agnosed with acute pyelonephritis.What is the antibiotic drug of choicefor treatment of this patient?

A. AmoxicillinB. NorfloxacinC. GentamicinD. ChloramphenicolE. Amikacin

117. Which group of adjuvantsincludes polyvinyl alcohol allowedfor use under the State Pharmacopoeiaof Ukraine regulations?

A. ProlongatorsB. PreservativesC. pH adjustersD. AntioxidantsE. Isotonizing agents

118. A patient with moderately

severe pneumonia has been admi-nistered ceftriaxone 1 time per day.The drug should be taken once a daydue to its following property:

A. Slow excretionB. Presence of bactericidal actionC. Wide range of actionD. Cumulative abilityE. Poor absorption from the injectionsite

119. A pharmacist is preparing an oi-ntment under aseptic conditions onthe sterile ointment base - composi-tion of vaseline and lanoline at aratio 6:4. The drug substance isincorporated by suspending. Suchtechnology of ointment preparationis typical for the following substance:

A. Benzylpenicillin sodium saltB. Sodium chlorideC. Thiamine chlorideD. Pilocarpine hydrochlorideE. Sodium sulfate

120. Mixers are used to obtaina homogeneous mixture of free-flowing materials. What mixers haveno rotating details?

A. Fluidized bed mixersB. Drum mixersC. Blade mixersD. Double cone blendersE. Centrifugal mixers

121. In the course of isoniazid identi-fication a pharmacy analyst hasthoroughly boiled the substance wi-th 2,4-dinitrochlorobenzene. Thesubstance colored yellow, after addi-ng alkaline solution it colored firstviolet and then brownish-red. As theresult of this reaction the followingaldehyde derivative is produced:

A. GlutaconicB. GluconicC. GlutamicD. GlyoxylicE. Hexanic

122. A routine inventory revealed acash shortage. Who has to reimburse


the sum of the revealed shortage?

A. CashierB. Pharmacy directorC. Deputy director of a pharmacyD. Department headE. Deputy head of a department

123. A 43-year-old patient with asevere form of rheumatoid arthritishas been administered a certain drugfor background therapy. Specify thisdrug:

A. MethotrexateB. Diclofenac sodiumC. NimesulideD. PrednisoloneE. Methylprednisolone

124. A process dealing with drawi-ng the documents, their processi-ng, circulation and storage iscalled records management. If alldocuments circulate through oneorganisation center, - office desk,- then such system of recordsmanagement is called:

A. CentralizedB. DecentralizedC. MixedD. ReferentE. Specialized

125. A pharmacy received aformula for an alcohol solution ofmethylene blue with unspecifiedalcohol concentration. In this case, apharmacist should use ethyl alcoholof the following concentration:

A. 60%B. 90%C. 70%D. 96%E. 40%

126. A pharmacist needs to prepare10,0 g of eye ointment vehicle. Whatamounts of lanolin and vaselineshould be taken?

A. 1,0 g of anhydrous lanolin and 9,0g of vaselineB. 1,0 g of anhydrous lanolin and 29,0g of vaselineC. 12,0 g of anhydrous lanolin and18,0 g of vaselineD. 27,0 g of anhydrous lanolin and 3,0g of vaselineE. 10,0 g of anhydrous lanolin and20,0 g of vaseline

127. Rifampicin is a cytochrome P450 inducer; therefore, its interactionwith other chemically active drugs:

A. Can decrease concentration ofother drugsB. Can increase concentration ofother drugsC. Has no effect on concentration ofother drugsD. Can result in binding with othermetabolitesE. Has no effect on toxicity of otherdrugs

128. Bronchodilatory effect of ashort-acting β2-adrenoceptor agoni-st, - salbutamol, - develops after:

A. 5-10 minutesB. 20-30 minutesC. 45-60 minutesD. 2-3 hoursE. 4-6 hours

129. Representatives of the familySolanaceae are widely used in medi-cal practice as alkaloid-containingplants. Which representative is thesource for production of semi-synthetic steroid hormones?

A. Solanum laciniatumB. Atropa belladonnaC. Datura StramoniumD. Hyoscyamus nigerE. Solanum tuberosum

130. Grass of Equisetum arvenseis recommend as a diuretic. Whatherbal raw material can be used asa substitute?


A. Herba Aervae lanataeB. Herba LeonuriC. Herba Menthae piperitaeD. Herba ConvallariaeE. Herba Adonidis

131. Under the State Pharmacopoeiaof Ukraine (appendix 2) leaves of gi-nkgo are standardized by the contentof:

A. FlavonoidsB. SaponinsC. AlkaloidsD. CoumarinsE. Chromones

132. During employment a pharmacymanager provides a dispensingchemist with job description. Suchcommunication is called:

A. DescendingB. AscendingC. ExternalD. InformalE. Non-verbal

133. Some of the local buisnesses hasentered into a temporary statutoryassociation to buy medical goodsfrom foreign manufactures. Namesuch association:

A. ConsortiumB. ConcernC. CorporationD. AssociationE. Syndicate

134. A pharmaceutical manufacturersets the price for a drug basing onits prime cost with premium. Whatmodel of pricing is it?

A. Cost-basedB. CompetitiveC. Demand-basedD. Supply-basedE. Breakeven

135. A dosage form for internal use,which consists of round or irregular-shaped uncoated grains containingmixture of active ingredients andadjuvants, is called:

A. GranulesB. TabletsC. TeaD. SpansulesE. Dragee

136. What method is recommendedby the State Pharmacopoeia ofUkraine for quantitative determi-nation of potassium chloridesubstance that is used in treatmentof hypokalemia?

A. ArgentometryB. BromatometryC. IodometryD. CerimetryE. Polarimetry

137. A 35-year-old patient withtachycardia has been administeredpropranolol. Which of the followingreactions may be caused by the useof beta-blockers?

A. BronchospasmB. Drug dependenceC. CumulationD. Blood pressure riseE. Constipations

138. Diazotization reaction with thefollowing azo compound is commonfor the substances with primary ami-no groups. What drug DOES NOTyield this reaction?

A. BarbitalB. BenzocaineC. Procaine hydrochlorideD. Procaineamide hydrochlorideE. Sulfanilamide

139. Cash receipts and paymentsat a pharmacy are recorded in acashbook. Which of the followi-ng cash transactions IS NOTREGARDED as a receipt transacti-on?


A. Issuing funds to be accounted forB. Recognizing cash receipts fromsales at a pharmacyC. Recognizing cash receipts fromsales at pharmacy stands and outletsD. Return of unused disbursementfundsE. Recognizing accrued salaries andadvance payable

140. Phytochemical workshop ofa factory manufactures pancreatin.What is the source material for obtai-ning pancreatin?

A. Pancreas of pigs or cattleB. Gastric mucosa of pigsC. Lungs of cattleD. Heart of cattleE. Egg white

141. The following substance is usedas an extractant in production of li-quid extracts:

A. EthanolB. AcetoneC. DichloroethaneD. ChloroformE. Glycerine

142. A patient with signs of morphi-ne intoxication has been deliveredinto an admission room. Name thenecessary antidote:

A. NaloxoneB. CollargolC. EssentialeD. EctericidumE. Trental (Pentoxifylline)

143. A patient, who had been taki-ng acetylsalicylic acid, has developedhemorrhages of mucous membranes.This phenomenon is associated with:

A. Inhibition of prothrombinsynthesisB. Increased absorption in gastroi-ntestinal tractC. Decreased absorption in gastroi-ntestinal tractD. Disorder of protein bindingE. Changed volume of distribution

144. A dispensing chemist withcalculated length of service of 7 yearshas fallen ill. What percent of thesum stated in her sick list would shereceive?

A. 80%B. 100%C. 70%D. 60%E. 50%

145. Quantitative determination ofsodium tetraborate according to theState Pharmacopoeia of Ukraineregulations is performed by means ofalkalimetry method in the presenceof:

A. MannitolB. Acetic anhydrideC. 96% ethanolD. Mercury (II) acetateE. Formaldehyde

146. Quantitative content of a certainmedicinal substance can be determi-ned by means of nitritometry only ifhydrolisis had been performed priorto it. Name this substance:

A. Streptocide solubleB. NorsulfazoleC. BenzocaineD. Dicain (Tetracaine)E. Procaine hydrochloride

147. Specialists of a pharmaceuticalenterprice confirm the identity ofCassia acutifolia herbal raw materi-al. During reaction with alkali itdeveloped cherry-red coloring. Whatsubstances were identified?

A. AnthraquinonesB. TanninsC. AlkaloidsD. GlycosidesE. Iridoids

148. Menthol has anesthetic andantiseptic effect. What herbal rawmaterial is the source of menthol?


A. Folia Menthae piperitaeB. Folia Uvae ursiC. Folia EucalyptiD. Folia SalviaeE. Folia Absinthii

149. The main method of quantitati-ve determination of corticosteroidsis:

A. SpectrophotometryB. PotentiometryC. CerimetryD. ArgentometryE. Acidimetry

150. Thyme grass is used for theproduction of herbal drugs for thetreatment of respiratory tract infecti-ons. Under the State Pharmacopoeiaof Ukraine the herbal raw materi-al is subject to chromatographicidentification by means of thin layerchromatography. What substancesare detected on the chromatographicplate after its treatment with duereagent?

A. Thymol and carvacrolB. Atropine and hyoscyamineC. Quercetin and rutinD. Apigenin and luteolinE. Arbutin and methyl arbutin

151. Eucalyptus leaves contai-ns essential oil and are used inproduction of bactericidal herbaldrugs. According to the StatePharmacopoeia of Ukraine thisherbal raw material can be identifi-ed with thin-layer chromatography.After the chromatographic plate isprocessed with reagent, the followi-ng should be identified:

A. CineoleB. QuercetinC. ScopoletinD. ApigeninE. Glaucine

152. Yarrow grass is a componentof herbal gastrointestinal remedi-es and is used to make herbaldrugs. According to the StatePharmacopoeia of Ukraine the quali-

ty of this herbal raw material isassessed by the content of:

A. Essential oil and proazulenesB. AlkaloidsC. PolysaccharidesD. Cardiac glycosidesE. Vitamines

153. To analyze market activity anddetermine its place within the marketa pharmaceutical company shouldevaluate its potential: strengths andweaknesses within the companyitself (internal factors), as well asopportunities and threats recei-ved from the market environment(external factors). It can be done wi-th:

A. SWOT analysisB. Ansoff’s matrixC. Boston Consulting GroupD. Porter’s matrixE. ABC analysis

154. Mercazolil (Thiamazole) is wi-dely applied in medicine as an anti-thyroid agent. What heterocycle is itsstructure based on?

A. ImidazoleB. TriazoleC. PyrazoleD. PyrroleE. Imidazoline

155. A 48-year-old woman addresseda dispensing chemist with complaintsof constipations developing after shehad started treatment of her chroniccardiovascular disease. What drugcan slow down intestinal peristalsis?

A. VerapamilB. Folic acidC. LosartanD. Ascorbic acidE. Enalapril

156. To identify medicinal substancescontaining calcium an analyticalchemist uses solution of:


A. Glyoxal-hydroxyanilB. Potassium thiocyanateC. β-naphtholD. HexamethylenetetramineE. Potassium permanganate

157. Calcium gluconate is tested forpresence of saccharose and reduci-ng sugars admixtures with copper-tartrate reagent. If these admixturesare present the substance colors:

A. RedB. BlueC. GreenD. TurquoiseE. White

158. A drug has just entered themarket and requires considerableinvestments, while does not returnsubstantial profits, and is currently atthe introduction stage. What groupof products (strategic economic uni-ts) does this drug belong to accordingto the Boston Consulting Group?

A. Problem childrenB. DogsC. StarsD. Cash cowsE. -

159. A 5-year-old boy suffering frompneumonia has problems with mucusexpectoration. A doctor prescribedhim a mucolytic drug that stimulatessurfactant synthesis. Name this drug:

A. AmbroxolB. CarbocisteineC. MucaltinD. AcetylcysteineE. Potassium iodide

160. A patient with peptic ulcerdisease has developed black-colored feces during combinedpharmacotherapy. Name the drugthat can be the cause of thisdevelopment:

A. Bismuth subcitrateB. FamotidineC. OmeprazoleD. LansoprazoleE. Ranitidine

161. A 43-year-old patient was deli-vered to an admission room withrenal colic attack. What group ofdrugs would be the most efficientduring the attack?

A. AntispasmodicsB. HepatoprotectorsC. AntacidsD. AntibioticsE. Cholagogues

162. A bus driver addressed apharmacy due to his suffering fromallergic rhinitis. What antihistaminewith minimal sedative action can yourecommend?

A. LoratadineB. ClemastineC. AstemizoleD. DiphenhydramineE. Chloropyramine

163. What antibiotic has beta-lactamcycle in its structure?

A. Benzylpenicillin potassium saltB. Doxycycline hyclateC. ChloramphenicolD. Streptomycin sulfateE. Lincomycin hydrochloride

164. A 36-year-old patient complai-ns of general weakness, somnolence,increased brittleness of nails, loss ofhair. The patient was diagnosed withiron-deficiency anemia. What drugshould be prescribed for treatment?

A. Ferric sulfateB. CyanocobalaminC. Folic acidD. Myelosanum (Busulfan)E. Riboxin (Inosine)

165. What hypotensive drug is anagent of choice for the patientssuffering from arterial hypertensi-on with concomitant type I diabetes


mellitus?

A. LisinoprilB. HydrochlorothiazideC. AtenololD. LabetalolE. Carvedilol

166. To identify ouabain (a cardi-ac glycoside) an analytical chemi-st performs a reaction with dini-trobenzene solution in alkaline medi-um. What molecule fragment can bedetermined by this reaction?

A. Five-membered unsaturatedlactone ringB. β-lactam cycleC. Pyridine cycleD. Benzene ringE. Purine cycle

167. A pharmacy employee hasto work during night time. Whatdocument must be used as a basis forpay rise calculation by an employerin this case?

A. Collective agreementB. Internal memorandumC. Employee’s applicationD. Expense reportE. Income summary

168. A pharmacy received a batchof drugs from a supplier. What typeof drug quality control should beperformed in the pharmacy by anauthorized person?

A. IncomingB. ChemicalC. PhysicalD. LaboratoryE. Complete chemical

169. A patient with essenti-al hypertension complains ofinfrequent occurrences of dry cough.Clinical and X-ray examination ofthe respiratory organs revealed nopathologies. What drug from thosetaken by the patient can cause coughas a side effect?

A. CaptoprilB. DiltiazemC. HydrochlorothiazideD. NebivololE. Prestarium (Perindopril)

170. A business entity workingin drug retail trade should keepthe documents confirming the factof a sale, where there are name,date, amount and series of a recei-ved drug stated, along with suppli-er information and license details.These documents are retained for:

A. 3 yearsB. 1 yearC. 2 yearsD. 6 monthsE. 5 years

171. A private pharmacy received asupply of a drug with 2,3-dihydro-2-methyl-1,4-naphthoquinone-2-sulfonate sodium as an activeingredient. Name this drug:

A. Vicasol (Menadione)B. RutinC. RiboflavinD. ErgocalciferolE. Cocarboxylase hydrochloride

172. A 53-year-old woman suffersfrom ischemic heart disease and angi-na pectoris. What drug can be used tostop angina pectoris attacks?

A. NitroglycerineB. Drotaverine hydrochlorideC. PropranololD. DipiridamolE. Acetylsalicylic acid

173. A patient is 20 years old. Aftershe was stung by a bee the patientdeveloped Quincke’s disease; rashin the form of blisters and papulaeappeared on her torso. First aid inthis case should start with admini-stering the following drug:


A. PrednisoloneB. PenicillinC. Fresh frozen plasmaD. Rheopolyglukin (Dextran)E. Haemodes

174. A patient with osteoarthritis(gonarthrosis) and peptic gastriculcer in anamnesis should be prescri-bed a NSAID (nonsteroidal anti-inflammatory drug). What NSAIDwould be the safest for this patient?

A. MeloxicamB. Acetylsalicylic acidC. IbuprofenD. IndometacinE. Metamizole sodium

175. In the course of clinicalinstrumental examination a 45-year-old patient has been diagnosed wi-th chronic helicobacter-associatedtype B gastritis. What group of drugsshould be prescribed first of all?

A. Anti-Helicobacter pylori agentsB. Prokinetic agentsC. AntacidsD. Reparative drugsE. Anti-muscarinic agents

176. When servicing customers itis necessary to maintain cash deskdiscipline. A cashier should makerecords in the cash book:

A. Immediately after the cashtransaction occurredB. MonthlyC. QuarterlyD. WeeklyE. At the end of a workday

177. Name the way of injectabulettaeapplication:

A. For injection solutions of drugsB. PeroralC. For implantationsD. VaginalE. Sublingual

178. What factors affect tablet disi-ntegration?

A. Amount and nature of disintegrati-ng agentsB. Poor flowabilityC. High specific gravity of powdersD. Tablet powder contains lamellarcrystalsE. Heterogeneity of granulatedmaterial

179. Cytitonum agitates respiratorycenter during asphyxiation, state ofshock, intoxication and respiratoryarrest. Seeds of a medicinal herb arethe source of this drug. Name thisherb:

A. Thermopsis lanceolataB. Linum usitаtissimumC. Plantago psylliumD. Cucurbita pepoE. Ricinus communis

180. During qualitative chemicalanalysis of nicotinic acid substancethe reaction was conducted, whi-ch resulted in blue coloring. Whatreagent was used?

A. Copper (II) sulfate solutionB. Sodium hydroxide solutionC. Iron (III) chloride solutionD. Thiocyanogen bromide reagentE. Nessler’s reagent

181. Pharmaceutical market subjectsthat purchase drugs and medicalproducts for further resale to makea profit are called:

A. DealersB. ManufacturersC. Consumer organisationsD. Government authoritiesE. Individual consumers

182. A pharmaceutical firm is unableto satisfy the demand for a drug.Specify the type of marketing taskedwith decrease of excessive demandfor a product by raising prices andstopping advertising and promotion:


A. DemarketingB. Creative marketingC. Promotional marketingD. SynchromarketingE. Remarketing

183. Cephalosporin structure is basedon the condensed system containingtwo cycles - β-lactam and:

A. DihydrothiazineB. ThiazolidineC. PyrrolizidineD. PhenothiazineE. Pyridine

184. To prepare eyedrops with antibi-otic a dispensing chemist has beenusing flowing steam sterilizationunder 100oC for 30 minutes. Whatantibiotic allows for such sterilizati-on?

A. Levomycetin (Chloramphenicol)B. Sodium benzylpenicillinC. Streptomycin sulfateD. BiomycinE. Erythromycin

185. A 48-year-old patient hasundergone incomplete amputation ofthe thyroid gland. Choose the drugfor replacement therapy in case ofhypothyroidism:

A. L-thyroxinB. HydrocortisoneC. InsulinD. MetoprololE. Prednisolone

186. Specify the medicinal substancewith pronounced hydrophobicproperties:

A. SulfurB. Basic bismuth nitrateC. Zinc oxideD. Sodium bromideE. Magnesium oxide

187. A 34-year-old patient sufferingfrom systemic lupus erythematosustakes methylprednisolone. Onexamination the patient’s bloodcalcium is revealed to be low.

A doctor suspects osteoporosisdevelopment. It is necessary toprescribe the patient calciumpreparations and:

A. Vitamin D3B. B-group vitaminsC. Vitamin CD. Vitamin AE. Vitamin E

188. A pharmacist has made an oilemulsion with vitamin E oil solutionintended for internal use. What is thebest approach to vitamin introducti-on into the emulsion?

A. Dissolve in oil before makingprimary emulsionB. Suspend in the prepared emulsionC. Dissolve in water for emulsiondilutionD. Dissolve in glycerineE. Dissolve in water to make primaryemulsion

189. Name the professional, who isauthorized to check financial andeconomic activity of an enterprise atthe request issued by an enterpriseor public authority:

A. AuditorB. Chief accountantC. Pharmacy managerD. InspectorE. Compliance officer

190. A 52-year-old patient has beendiagnosed with gouty arthritis, phase2. What drug should be basic intreatment of this patient?

A. AllopurinolB. HydrochlorothiazideC. ParacetamolD. FurosemideE. Penicillin

191. Speed of blend powderdampening can be significantlyaffected by package material. Whatcapsules protect powders from dampair the best?


A. WaxedB. ParchmentC. Soft gelatineD. PolyethyleneE. Paper

192. Anthracene derivativeshave two main directions ofpharmacological activity: purgativeand litholytic. What leads to the di-fference in pharmacological activityof different anthracene derivatives?

A. Hydroxyl group placementB. Amount of sugar residuesC. Presence of methyl groupsD. Presence of carboxyl groupsE. Polymerization

193. A pharmacy manager hascalculated a certain indicator of effi-ciency of pharmacy’s economic acti-vity as percentage ratio of profits toturnover in retail prices. What indi-cator is it?

A. ProfitabilityB. Turnover growth rateC. Turnover expenditureD. Inflation rateE. Trade stock standard

194. A pharmacy sells standard drugsto population. What is a prime costof sold goods, if the retail price is 300000 UAH, and the total markup is120 000 UAH?

A. 180 000 UAHB. 100 000 UAHC. 50 000 UAHD. 120 000 UAHE. 300 000 UAH

195. Pharmacy employees shouldmeet universal qualification requi-rements. Who has the right to holda position of a prescription drugsdepartment manager?

A. Dispensing chemistB. PharmacistC. Sanitary assistantD. PackagerE. Manager

196. During the period when a cashregister is inoperable and undergoesrepairs it is possible to performpayment operations using:

A. Transactions logbook and receiptsB. Payment ordersC. Check bookD. Credit and debit cash ordersE. Accompanying notes

197. An analytical chemist performsidentification of lidocaine hydrochlori-de. According to the StatePharmacopoeia of Ukraine thepresence of chloride ions can beconfirmed by means of reaction wi-th silver nitrate solution resulting in:

A. White caseous precipitateB. Green fluorescenceC. Violet coloringD. Yellow precipitateE. Blue coloring

198. A pharmacist has dissolved amedicinal substance in sterile puri-fied water to make an eye ointment.Specify this medicinal substance:

A. Pilocarpine hydrochlorideB. XeroformC. MentholD. Basic bismuth nitrateE. Purified sulfur

199. What tax is registered as a localone in a pharmacy budget?

A. Single taxB. Corporate income taxC. Value-added taxD. Income taxE. Excise tax

200. An important indicator of busi-ness activity is profitability of a busi-ness. Specify the indices that can beused to measure the profitability:

A. Profit/turnoverB. Turnover/cost priceC. Turnover/incomeD. Income/turnoverE. Liquidity/solvency

INSTRUCTIONAL BOOK

Testing Board

TEST ITEMS FOR LICENSING EXAMINATION: KROK 2. PHARMACY.

Kyiv. Testing Board.

(English language).

Approved to print 01.03/№22. Paper size 60х84 1/8

Offset paper. Typeface. Times New Roman Cyr. Offset print.

Conditional print pages 16. Accounting publishing pages 20.

Issue. 261 copies

List of abbreviations

A/G Albumin/globulin ratio A-ANON Alcoholics anonymous ACT Abdominal computed tomography ALT Alanin aminotranspherase AP Arterial (blood) pressure AST Aspartat aminotranspherase BP Blood (arterial) pressure BR Breathing rate bpm Beats per minute C.I. Color Index CBC Complete blood count CHF Chronic heart failure CT Computer tomography DIC Disseminated intravascular coagulation DCC Doctoral controlling committee DM-2 Non-Insulin dependent diabetes mellitus DTP Anti diphtheria-tetanus vaccine ECG Electrocardiogram ESR Erythrocyte sedimentation rate FC Function class FEGDS Fibro-esphago-gastro-duodenoscopy Gy Gray GIT Gastrointestinal tract Hb Hemoglobin HbA1c Glycosylated hemoglobin Hct, Ht Hematocrit HDL

HR

High-density lipoproteins

Heart rate IDDM Insulin dependent diabetes mellitus IHD Ischemic heart disease IU International unit MSEC Medical and sanitary expert committee NIDDM Non-Insulin dependent diabetes mellitus pCO2 CO2 partial pressure pO2 O2 partial pressure Pm Per minute Ps Pulse rate R Roentgen RBC Red blood count Rh Rhesus RR Respiratory rate S1 (S1) Heart sound 1 S2 (S2) Heart sound 2 TU Tuberculin unit U Unit USI Ultrasound investigation V/f Vision field WBC White blood count X-ray Roentgenogram

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