DS. HUNH TRNG HIP I CNGEntamoeba histolytica (Amip)Giardia lambliaT trng, rut non, rut gi,ng mt, ti mtTiu !"#$%im, &'!() I CNGTrichomonas vaginalisCandida albicanTi*t ni+u,in" -.!%im n"i/m I CNG%i 0"u1n 02 0"3Helicobacter pylori 45 %6NG C7 NIT8&9:;"?i @in "Ap "Bp t"u n" )ngN,thiazolNCNimidazol12345 NHOM 5-NITROIMIDAZOLNNR1O2N R2135CAU TRUC CHUNGC che tac on T!nh "h#$ o%& hoa "h#$ '" (e) "h! Goc t#* +o tha) &a he thon a en,() -.a t/0nh nha1n o1& a2( ADN c.$a 3/oto,oa(Cac protozoa giau A va T nh Trich., Entamoeba) DNCCED NHOM 5-NITROIMIDAZOLCH2CHCH3OHCH2CHCH2ClOHR1 R2 DANH PHPTN THNGCH3CH31,2-dimethyl-5-nitro-1H-imidazolDimetridazolCH2CH2OH CH32-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-olMetronidazolCH31-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-olSenidazolCH31-loro-3-(2-methyl-5-nitro1H-imidazol-1-yl)propan-2-olOrnidazol NHOM 5-NITROIMIDAZOLN (CH2)2O N (CH2)2R1 R2 DANH PHPTN THNG(CH2)3OH CH33-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-1-ol!ernidazolCH32-methyl-5-nitro-1-(4-pyridyl ethyl)-1H-imidazol#anidazolH 4-$2-(nitro-1H-imidazol-1-yl)ethyl%morpholinNimorazol NHOM 5-NITROIMIDAZOL(CH2)2NHCOCH3S&NSO2CH3O(CH2)2SO2CH2CH3CH31-[2-(ethylsulfonyl)ethyl] 2-methyl-5-nitro-1H-imidazolinidazolCH3!-[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl methyl thio"ar#amatCamidazolCH2CH2OH 2-[2-($-%uoro&henyl) -5-nitro-1H-imidazol-1-yl] ethan-1-ol'lunidazolCH3CH2OCO!H2(1-methyl-5-nitro-1H-imidazol-2-yl)methyl "ar#amat(onidazol

CH31-(1-methyl-5-nitro-1H-imidazol-2-yl)-3-(methylsulfonyl)imidazolidin-2-onSatranidazol NHOM 5-NITROIMIDAZOL 4 5I67U CH6HHOO'NH3NH3'OHCH3NNHCH3NNHCH3HNO3(H2SO4)NNHO2N CH3135 NHOM 5-NITROIMIDAZOL 4 5I67U CH6NNHO2N CH3135 (CH3)2SO4(HCOOH)NNCH3O2N CH3135D&)et/&+a,o8NNHO2N CH3135NNCH2CH2OHO2N CH3135ClCH2CH2OHMet/on&+a,o8 NHOM 5-NITROIMIDAZOL 4 5I67U CH6NNHO2N CH3135OCH3NNO2N CH3OHCH3135O/n&+a,o8NNHO2N CH3135NNCH2CH2SCH2CH3O2N CH3135(rCH2CH2SCH2CH3O)y ho*aNNO2NCH2CH2S CH2CH3OOCH3T&n&+a,o8 9I6:M 5;NH5ha$n #n )a?.5ARAMOM]CINTD t#n t#* nh# a)&noK&+ I^AWJCD Fa)&E /.otB Giardia Nh&e_) Cryptosporidum parvum/AIDW T/< Kan )anB &.n UAODLDLNCIN5NC TPNCJIO, ,;IL5NC IRNGJ%i )in"