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Using Ovid® for Meta-Analysis & Systematic ReviewsChris Jung정민우Wolters Kluwer Health – Ovid 한국지사대표

Agenda

2Using Ovid® for Meta-Analysis & Systematic Reviews

1. Preparing for a Systematic Review

2. Ovid® MEDLINE vs. PubMed Content Platform Features Search Functionality Results Management Multiple Database Searching &

Deduplication

3. Structured Search Example

4. Ovid REMINER

3Ovid® MEDLINE PsycINFO・講習会

Preparing for a Systematic Review

Creating a Systematic Review


Source: http://navigatingeffectivetreatments.org.au/

➀

➁

➂ Update, as required

Search

Meta-Analyse

Determining the question


The PICO process is a technique used in evidence based practice to answer a clinical question PICO is an acronym for: Population, Intervention,

Comparison, Outcome

Source: Macquarie University Library, Libguides: http://libguides.mq.edu.au/content.php?pid=371659&sid=3291432

Defining a question


Among Type 2 diabetic patients, do improved lifestyle habitsaffect HbAlc levels?

P Type 2 diabetic patients

I improved lifestyle habits

C HbAlc levels without improved lifestyle habits

O changes in HbAlc levels

Search for relevant data


Cochrane collaboration recommends searching in Cochrane Central Register of Controlled Trials, Medline and Embase.

Search for relevant data


SHKW

SHKW

SH

KWSH

KW

Topical lidocaine for neuropathic pain in adults,Cochrane Database of Systematic Reviews, Volume (6), 2016.

SH: Subject HeadingsKW: Keywords

Methodological limits• RCT and CCT (.pt)• Studies about drug therapy

Ovid®マルチファイル検索・上級検索モード


Ovid® MEDLINE vs. PubMed

Introduction to MEDLINE on Ovid®


Database Creation

MEDLINE In Process Segments

MEDLINE SegmentEpub Ahead of Print

Publisher Submitted

MEDLINE In Process

Pubmed Not MEDLINE

In Data Review

MEDLINE In Process MEDLINE

PubMed Search Page & Ovid®


Advanced Search, Search Fields &

MultiField Search

Find Citation

Clinical Queries

Mapping and Search Tools

PubMed Search Page & Ovid®


Find Citation

Clinical Queries

Mapping and Search Tools

Advanced Search, Search Fields & Multi-Field

Search

PubMed Search – automatic explode


Ovid® MEDLINE Search – mapping process


Explode –include all narrower

terms

Focus – find records where

this is the main concept

Ovid® MEDLINE Search – mapping process


Export Options


Text file or CSV Select all results

or a range

My NCBI vs.My Projects


Add sub-foldersSearch all or selected projects

Collaborate with Annotations

Send Auto-Alert results directly to a project folder

Search multiple databases with deduplication


Search multiple databases with deduplication


Multiple database results combined, ranked by

relevancy (Basic Search) or chronological order (Advanced Search)

Filter results display by database


Structured Search Example

StructuredSearching in Ovid®


Among Type 2 diabetic patients, do improved lifestyle habits affect HbAlc levels?

Type 2 diabetes lifestyle HbAlc

Among Type 2 diabetic patients, do improved lifestyle habitsaffect HBAlc levels?

HLA PD Day

http://access.ovid.com/training/pico/english/pico_widget.htm

Structured Searching in Ovid®


Map keywords to controlled Terms



Click on the scope note to see more

information about the subject heading



(diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulin dependent OR slow

onset OR stable OR type?2 OR type?ii)) OR mody OR niddm

Adjacency operator (searches for words

based on their proximity)

Truncation inside a word (stands for any

letter or nothing)



Click on the subject heading to

view the full thesaurus



Select ‘Explode’ to search the

narrower terms together with the

main term



Select a subheading to

refine the search to a specific

aspect of the controlled term, or leave blank to

perform a general search

Choose the Therapy subheading to limit results

to records indexed with the Therapy aspect of

Diabetes Mellitus, Type 2



‘exp’ means ‘explode’ (the search includes the narrower

terms as well as the main term)

‘/’ means this is a subject heading

‘[ ]’ contains the specified subheading(s)



Deselect ‘Map Term to Subject Heading’ for

keyword search



Select sets and combine with ‘AND’ or ‘OR’






exp Diabetes Mellitus, Type 2/

((diabetes adj2 (adult onset OR ketotis resistant OR maturity onset OR non?insulindependent OR slow onset OR stable OR type?2 OR type?ii)) OR mody OR niddm)



life?style*

Right-side Truncation (search for all words

beginning with certain letters)







exp Life Style/

life?style*




What you do select when searching?



Where you do you click first?



hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR

(glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR

(h?emoglobin* adj1 a1*)



Where you do you click next?



Where you do check?



What you do de-select when

searching?



How do you combine the

searches?







exp Life Style/

life?style*


hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR (glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR (h?emoglobin* adj1 a1*)

exp Hemoglobin A, Glycosylated/



Final set – combine 3 subsets with ‘AND’



Clinical Queries - Limit to types of studies







exp Life Style/

life?style*


hb?a1* OR (a1* adj1 (h?emoglobin* adj1 glycosylated)) OR (glycated adj1 h?emoglobin*) OR (glycoh?emoglobin a) OR (glycosylated a1* adj1 h?emoglobin*) OR (glycosylated h?emoglobin*) OR (h?emoglobin* adj1 a1*)

exp Hemoglobin A, Glycosylated/

middle aged(45 years plus)

Clinical Queries:therapy (best balanceof sensitivity andspecificity



Save results in a Project folder

Meta-Analysis: Extraction of relevant data


Source: http://training.cochrane.org/

Meta-Analysis: Analyze and combine the data


Source: http://support.sas.com/kb/35/addl/fusion_35143_1_forestplot_2col.gif

Auto-Alerts – keep track of new research


Auto-Alerts – keep track of new research


Automatically run search

when database is

updated

Receive results via email and

deliver directly to a

project folder

Ovid REMINER


Use REMINER…• If you have a collection of references from a database, or

another source, and want to find more of the same type of article, or set up an alert…

• If you have a structured Ovid search strategy based on mapping and search tools, and want to add a reliable set of keywords to broaden out your search…

• If you want to turn a gold standard list of references into a search filter for your library clients…

• If you want to explore the characteristics of the references which were used to produce a systematic review – identify similarities – subjects, authors, etc…

Ovid REMINER


Export target records

Ovid REMINER


Export as an ‘Excel Sheet’

and select desired fields (ab, sh, ti, ui/an, etc)

Ovid REMINER


Convert into .xlsx file format and confirm desired fields from selected database

Ovid REMINER


Upload the .xlsx file and ‘Submit Query’

http://tools.ovid.com/REMINER/

Ovid REMINER


Select required fields and words and

phrases from the terms list to include in your search. Edit

as desired.

Ovid REMINER


Confirm for sensitivity vs. specificity

Sensitivity = 23/93or 24.7% of Gold Standard Set

Ovid REMINER


Review Gold Standard

references or references not

included in search results for key subjects and

confirm via scope notes

Ovid REMINER


Edit the search to fit intention (sensitivity vs.

specificity), and Run Search

Ovid REMINER


Export a record from in Word format, and include the

Search History

Confirm for sensitivity vs. specificity

Sensitivity = 93/93or 100% of Gold Standard Set

Review results

Ovid REMINER


Copy the whole search

statement

Creating a Search Link


Input the required information and paste the whole

search statement

Use the Search Link, as desired

http://demo.ovid.com/demo/search_link/search_link.htm

How to learn more


Ovid Resource Center: resourcecenter.ovid.com

How to learn more


PICO Resource Center: access.ovid/com/training/pico/english

How to learn more


Ovid Expert Searches: http://resourcecenter.ovid.com/site/resources/expert_search/healthexp.html

Ovid REMINER:


Filter Link Builder:


Ovid Database Shortnames:

http://www.ovid.com/site/support/tech_support.jsp#tabs5

Widget Builder:

http://tools.ovid.com/widget/

Flinders Filters Smart Searching: Logical Steps to Building and Testing your LiteratureSearch:

https://sites.google.com/site/smartsearchinglogical/home

http://resourcecenter.ovid.com/site/resources/expert_search/healthexp.html



http://www.ovid.com/site/support/tech_support.jsp#tabs5

http://tools.ovid.com/widget/

https://sites.google.com/site/smartsearchinglogical/home

How to learn more


[email protected]

mailto:[email protected]

mailto:[email protected]

Using Ovid® for Meta-Analysis & Systematic ReviewsChris JungRegional Sales Manager, South Korea

2016

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