Web-Based Electronic Data Collection System to

Support Electrochemotherapy Clinical Trial

IEEE TRANSACTIONS ON INFORMATION TECHNOLOGY IN BIOMEDICINE, VOL. 11, NO.

2, MARCH 2007Presentor:陳麒文

information and communication technology (ICT)

electronic data collection (EDC) electronic patient records (EPR) clinical-data-management systems (CDMS) European Standard Operating Procedures of El

ectrochemotherapy and Electrogenetherapy (ESOPE)

case report forms (CRFs)

DesignDesign

centralized database development of an application for easy data su

bmission to the central database computer- and platform-independent solution; remote-application maintenance and upgrading application must work or be accessible inside t

he clinical network respecting the “privacy” and ownership of eac

h medical center’s data

..

..

Data storedData stored

patient data (demography, medical history, physical examination, etc.);

therapy data (sessions, evaluation visits, follow-up visits, etc.);

data from the local databases of Cliniporator medical devices;

digital images of tumor nodules in different phases of therapy and follow up

WEB-BASED EDC APPLICATION

web forms (digital CRF) for data entry; upload of images interactive human map for marking tumor loca

tions; local MDB database upload from the Clinipora

tor medical device; basic online statistics; interactive tumor-history graph

Upload of Images

Auto create smaller preview picAuto create smaller preview pic Comments to every picComments to every pic Image can be manage by groupsImage can be manage by groups Download!Download!

Basic Online Statistics

number of treated patients per center number of ended therapies number of tumor treatments uploaded corresponding local databases distribution of applications of different electro

de types different drugs used

Interactive Tumor-History Graph

interactive Flash presentation of the tumor history for each patient in the database

Each timeline is accompanied by data of tumor initial size and location, therapy, drug, and pulse parameters, as well as tumor images

SECURITY MEASURES

server level; Data transmission level; application level

DATA QUALITY AND DATA ANALYSIS

It is too optimistic to expect that all the data are entered correctly

Check table form-completeness-notification for the statistical analysis, the most suitable for

m of data representation is a “flat table” (one single table with all the required data included in it).

They did not agree on the advantages of Web-based medical-record system over the usual (non-Web based) computer medical-record system. Nevertheless, all the users agreed that an obvious advantage of this system was the support of multimedia content

ConclusionConclusion

The Internet technology fills the gap between application development and deployment

Users/researchers can promptly shape the application design and functionalities

Q&AQ&A