xx kk · monohydrate under conditions of hiperoxaluria (ci(ca2+) = 7.5 ∙ 10–3 mol dm–3 and...

KONTAKT/CONTACT:e-mail: [email protected]

tel.: +385 (0) 1 4597 118fax: +385 (0) 1 4597 142

XXVI

. HSK

IKI

26. hrvatski skup kemičara i kemijskih inženjera, Šibenik, 2019. 26th Croatian Meeting of Chemists and Chemical Engineers, Šibenik, 2019

26. hrvatski skup kemičara i kemijskih inženjera s međunarodnim sudjelovanjem

4. simpozij Vladimir Prelog 9. – 12. travnja 2019.

Šibenik, Amadria park (Solaris)

Knjiga sažetaka

26th Croatian Meeting of Chemists and Chemical Engineers with international participation

4th Symposium Vladimir Prelog 9–12 April 2019

Šibenik, Amadria park (Solaris), Croatia

Book of Abstracts


Znanstveno‐organizacijski odbor Scientific and Organizing Committee Aleksandra Sander (predsjednica) Mario Vazdar (dopredsjednik) Jasna Prlić Kardum (tajnica) Danijela Barić Zdenko Blažeković Marijana Đaković Vesna Gabelica Marković Nives Galić Zvonimir Katančić Borislav Kovačević Hrvoje Kušić Sanja Lučić Blagojević Snježana Osmak Jelena Parlov Vuković Marko Rogošić Marin Roje Vesna Tomašić Dubravka Turčinović Lidija Varga‐Defterdarović Miroslav Žegarac Olgica Martinis

Lokalni organizacijski odbor Local Organizing Committee Nenad Kuzmanić Sanja Slavica Matešić Melinda Grubišić Reiter

Međunarodni organizacijski odbor International Organizing Committee Albin Pintar, Slovenia Saša Omanović, Canada Valerio Causin, Italy Andrea Katović, Italy

Organizatori / Organizers Hrvatsko društvo kemijskih inženjera i tehnologa / Croatian Society of Chemical Engineers Hrvatsko kemijsko društvo / Croatian Chemical Society

Tajništvo skupa / Secretariat of the Meeting Jasna Prlić Kardum Fakultet kemijskog inženjerstva i tehnologije Sveučilišta u Zagrebu Marulićev trg 19, HR‐10 000, Zagreb, Hrvatska Tel.: 01/4597‐223 e‐pošta: [email protected] www.26hskiki.org

Grafička priprema programa / Design & Layout Zdenko Blažeković


IMPRESUM

Organizatori / Organizers

Hrvatsko društvo kemijskih inženjera i tehnologa Croatian Society of Chemical Engineers

Hrvatsko kemijsko društvo Croatian Chemical Society

Izdavač / Published by

Hrvatsko društvo kemijskih inženjera i tehnologa Croatian Society of Chemical Engineers

Urednici / Editors

Nives Galić / Marko Rogošić

Grafička priprema / Design & Layout Zdenko Blažeković

Recenzenti sažetaka / ReviewersDanijela Barić

Marijana Đaković Nives Galić

Zvonimir Katančić Borislav Kovačević

Hrvoje Kušić Jasna Prlić Kardum

Marko Rogošić Marin Roje Aleksandra Sander Vesna Tomašić Lidija Varga Defterdarović Mario Vazdar

ISBN: 978‐953‐6894‐67‐3

Mjesto održavanja Skupa / Meeting Venue Šibenik

Amadria Park (Solaris) Hoteli Solaris 86

Šibenik Croatia

Tel: +385 (0) 22 363 951 Fax: + 385 22 363 945

https://www.amadriapark.com/location/sibenik

Zagreb, 2019.


P‐A102 Gordan HORVAT, Antun Barišić, Tamara Rinkovec, Nikola Cindro, Leo Frkanec, Vladislav Tomišić Termodinamičko i strukturno istraživanje kompleksiranja alkalijskih kationa s amidnim derivatima kaliks[4]arena u nekoliko organskih otapala Thermodynamic and structural studies of the complexation of alkali‐metal cations with calix[4]arene amide derivatives in several organic solvents

157

P‐A10 Željka SOLDIN, Dijana Kos, Boris‐Marko Kukovec, Marijana Đaković Reakcije heksafluoroacetilacetonatnih kompleksa bakra(II) i nikla(II) s amidnim derivatima piridina: sinteza i karakterizacija. Reactions of copper(II) and nickel(II) hexafluoroacetylacetonates with pyridine‐based amides: synthesis and characterization.

158

P‐A104 Zlata LASIĆ, Irena Radić, Luka Jerić, Nives Galić Razvoj metode tekućinske kromatografije ultravisoke djelotvornosti za analizu razgradnih produkata lijeka elvitegravira Development of ultra‐high performance liquid chromatographic method for the analysis of Elvitegravir degradation products

159

P‐A105 Zrinka MASTELIĆ SAMARDŽIĆ, Moris Mihovilović, Ozren Wittine, Aida Omerbašić, Vitomir Vušak Primjena protočne kemije u razvoju procesa sinteze aktivnih farmaceutskih supstancija Application of flow chemistry in process development of active pharmaceutical ingredients (APIs)

160

P‐A106 Zvonimir JAŽO, Mateo Glumac, Josip Radić Analitičko istraživanje tla na području Dalmacije Analytical study of soils in Dalmatia

161

P‐A107 Anamarija Stanković, Silvija Šafranko, Jasminka Kontrec, Branka Njegić Džakula, Daniel Mark Lyons, Berislav MARKOVIĆ, Damir Kralj Istraživanje morfoloških karakteristika kalcijeva oksalata monohidrata: formiranje kristala u sustavima različite kemijske kompleksnosti Investigating the morphological properties of calcium oxalate monohydrate: crystal formation in systems with different chemical complexity

162

P‐A108 Maja ANIČIĆ, Mateja Budetić, Mirela SAMARDŽIĆ Primjena tenzidnog senzora pri optimiranju sastava formulacije oplemenjivača rublja The application of surfactant sensor in optimization of composition of fabric softeners formulation

163

P‐A109 Marina POLJAK, Adriana Kenđel, Ines Primožič, Snežana Miljanić, Tomica Hrenar Spektroskopsko i kemometričko istraživanje mirisnih spojeva Spectroscopic and chemometric investigation of odorants

164

P‐A110 Martina Andrijević, Andrea DANDIĆ, Mateja Budetić, Mirela Samardžić, Aleksandar Sečenji Sinteza i karakterizacija novog fluorescentnog indikatora za detekciju selenija Synthesis and characterization of new fluorescent indicator for selenium detection

165

P‐A111 Irena G. STARÁ, Ivo Starý, Jiří Klívar, Michal Šámal, Lucie Bednárová Dijastereomerno i enantiomerno čisti helicenski 2,2’‐bipiridini: novi tip kirooptičkih prekidača Diastereo‐ and enantiopure helicene 2,2’‐bipyridines: a new type of chiroptical switches

166

POSTERSKA PRIOPĆENJA / POSTER PRESENTATIONS KEMIJSKO I BIOKEMIJSKO INŽENJERSTVO / CHEMICAL AND BIOCHEMICAL ENGINEERING

167

P‐B1 Joško BARBARIĆ, Krunoslav Žižek Priprava i karakterizacija čvrstih disperzija lurasidon‐hidroklorida Preparation and characterization of lurasidone hydrochloride solid dispersions

168

P‐B2 Matija GRETIĆ, Gordana Matijašić, Mateja Štanfel, Nikola Rimac Priprava i in vitro karakterizacija farmaceutskih peleta Preparation and in vitro characterization of pharmaceutical pellets

169

P‐B3 Ana PETRAČIĆ, Aleksandra Sander, Matija Cvetnić Ekstrakcija metala, bora i fosfora iz otpadne životinjske masti pomoću niskotemperaturnih eutektičnih otapala Extraction of metals, boron and phosphorus from waste animal fat using deep eutectic solvents

170

P‐B4 Krunoslav ŽIŽEK, Iva Gavran, Joško Barbarić Priprava i karakterizacija minitableta za oralnu primjenu lurasidon‐hidroklorida Preparation and characterization of mini‐tabs for oral delivery of lurasidone hydrochloride

171


162

Investigating the morphological properties of calcium oxalate monohydrate: crystal formation in systems with different chemical complexity

Istraživanje morfoloških karakteristika kalcijeva oksalata monohidrata: formiranje kristala u sustavima različite kemijske kompleksnosti

Anamarija Stanković,1 Silvija Šafranko,2 Jasminka Kontrec,3 Branka Njegić Džakula,3 Daniel

Mark Lyons,3 Berislav Marković,1 Damir Kralj3 1Department of Chemistry, J. J. Strossmayer University of Osijek, Croatia

2Faculty of Food Technology Osijek, J. J. Strossmayer University of Osijek, Croatia 3Ruđer Bošković Institute, Zagreb, Croatia

E‐mail: [email protected]

Urolithiasis, the formation of urinary stones in different parts of kidney or bladder, is a specific form of pathological biomineralization [1]. Recently, an increasing prevalence of kidney stones in industrial countries is observed and the interest of scientists to explain their pathogenesis with a special focus on calcium oxalate stones is renewed. Calcium oxalates crystallize in the form of hydrated salts: thermodynamically stable calcium oxalate monohydrate [2,3] (COM, CaC2O4∙H2O), metastable dihydrate [4,5] (COD, CaC2O4∙2H2O) and trihydrate [6,7] (COT, CaC2O4∙3H2O). The kidney stones formation under biological conditions can be triggered by various metabolic disorders such as: hypercalciuria, hypocitraturia, hyperoxaluria and the change in the urine acidity. The mechanisms and the conditions under which they crystallize are still not completely clarified [1]. In this work, the spontaneous precipitation and characterization of calcium oxalate monohydrate under conditions of hiperoxaluria (ci(Ca2+) = 7.5 ∙ 10–3 mol dm–3 and ci(C2O4

2–) = 6.0 ∙ 10–3 mol dm–3) is reported. The experiments were conducted in a model system (Ic = 0.3 mol dm–3 NaCl, which imitates the physiological conditions in the human body) at two initial pH (pHi = 5.0 and 9.0) and with the addition of amino acids reportedly important for pathologic biomineralization [8,9]. The amino acids selected for the addition are often found in the urine of healthy people and in the organic matrix which is an integral part of kidney stones. The reactant solutions were mixed under controlled hydrodynamic and thermodynamic conditions. Changes in the structure and morphology of precipitated calcium oxalate monohydrate were observed by means of PXRD, SEM, IR and TGA. References [1] B. Hess, R. L. Ryall, J. P. Kavanagh, S. R. Khan, D. J. Kok, A. L. Rodgers and H. G Tiselius, Eur. Urol. 40 (2001) 220‐230. [2] Lj. Brečević and D. Kralj, J. Cryst. Growth 79 (1986) 178‐184. [3] Lj. Brečević, D. Kralj and J. Garside, J. Cryst. Growth 97 (1989) 460‐468. [4] C. Conti, M. Casati, C. Colombo, M. Realini, L. Brambilla and G. Zerbi, Spectrochim. Acta A: Mol. Biomol. Spectrosc. 128 (2014) 413‐419. [5] P. Brown, D. Ackermann and B. Finlayson, J. Cryst. Growth 98 (1989) 285‐292. [6] D. Škrtić, M. Marković, Lj. Komunjer and H. Füredi‐Milhofer, J. Cryst. Growth 66 (1984) 431‐440. [7] D. Škrtić, H. Füredi‐Milhofer and M. Marković, J. Cryst. Growth 80 (1987) 113‐120. [8] K. Kohri, M. Takada, Y. Katoh, K. Kataoka, M. Iguchi and T. Kurita, Int. Urol. Nephr. 21 (1989) 9‐16. [9] S. S. Atanassova, P. Panchev and M. Ivanova, Amino Acids 38 (2010) 1277‐1282.

xx kk · monohydrate under conditions of hiperoxaluria (ci(ca2+) = 7.5 ∙ 10–3 mol dm–3 and...

Documents