實驗室簡介 final

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National Chiao Tung University, Taiwan Biomechanics and Biomechanics and Medical Application Medical Application Laboratory Laboratory Bing-Shiang Yang, Ph.D., Bing-Shiang Yang, Ph.D., P.E P.E Department of Mechanical Engi Department of Mechanical Engi neering neering

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Page 1: 實驗室簡介 Final

National Chiao Tung University, Taiwan

Biomechanics and Biomechanics and Medical Application Medical Application

LaboratoryLaboratory

Bing-Shiang Yang, Ph.D., P.EBing-Shiang Yang, Ph.D., P.EDepartment of Mechanical EngineerinDepartment of Mechanical Engineeringg

Page 2: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

2

PeoplePeople

10 graduate students (1 doctoral std)10 graduate students (1 doctoral std) 10 undergraduate students10 undergraduate students 1 part-time assistant1 part-time assistant

CollaboratorsCollaborators Brain Research Center, Dept. of EE, CS, NCTUBrain Research Center, Dept. of EE, CS, NCTU Hsinchu General HospitalHsinchu General Hospital Chang Gung Memorial HospitalChang Gung Memorial Hospital National Taipei University of TechnologyNational Taipei University of Technology

Page 3: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

3

Facility Facility

120 m120 m22 lab space lab space Motion analysis systemMotion analysis system Electromyography measurementElectromyography measurement Surface reaction measurementSurface reaction measurement Transcranial magnetic stimulatorTranscranial magnetic stimulator Musculoskeletal modeling packageMusculoskeletal modeling package Net conference systemNet conference system

Page 4: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

4

FundingFunding

National Science CouncilNational Science Council Ministry of EducationMinistry of Education

Page 5: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

5

Stroke neuro-rehabilitationStroke neuro-rehabilitation

Integrated smart living technologyIntegrated smart living technology– Biomechanical considerations for living Biomechanical considerations for living

environmentenvironment– Interactive fitness/training equipment dInteractive fitness/training equipment d

evelopmentevelopment

Light weight vehicle for the elderlyLight weight vehicle for the elderly

Current Research Topics Current Research Topics

Page 6: 實驗室簡介 Final

National Chiao Tung University, Taiwan

The feasibility of using vibratory The feasibility of using vibratory afferent input for stroke hand afferent input for stroke hand rehabilitationrehabilitation

S-J Chen, K-T Huang, P-C Lin, & S-C LiaoS-J Chen, K-T Huang, P-C Lin, & S-C LiaoCollaborators: Collaborators: Hsinchu General Hospital &Hsinchu General Hospital &

Chang-Gung Memorial HospitalChang-Gung Memorial Hospital

Stroke Neuro-rehabilitation

Page 7: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

7

Introduction Introduction

Stroke is the leading cause of long-term disability Stroke is the leading cause of long-term disability (Turney et al. 1984; American Heart Association 2005)(Turney et al. 1984; American Heart Association 2005)

Hand dysfunction is the most common impairmenHand dysfunction is the most common impairment post-stroke. t post-stroke. (Butefisch et al. 2003; Lang and Schieber 2003)(Butefisch et al. 2003; Lang and Schieber 2003)

Lack of finger independency or muscle selectivity iLack of finger independency or muscle selectivity is a primary contributor s a primary contributor (Li et al. 2003; Lang & Schieber 2003, (Li et al. 2003; Lang & Schieber 2003, 2004)2004)

… … A strategy to reduce abnormal coupling?A strategy to reduce abnormal coupling? Muscle vibration affects the motor-evoked potentiMuscle vibration affects the motor-evoked potenti

al (MEP) of the vibrated muscle in healthy and possal (MEP) of the vibrated muscle in healthy and possibly stroke individuals. ibly stroke individuals. (Siggelkow et al. 1999; Rosenkranz a(Siggelkow et al. 1999; Rosenkranz and Rothwell 2003; Yang et al. 2006).nd Rothwell 2003; Yang et al. 2006).

Page 8: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

8

Aim 1Aim 1

Identify the patterns of muscle vibration-modulateIdentify the patterns of muscle vibration-modulated hand corticomotor excitability in individuals follod hand corticomotor excitability in individuals following stroke (Yang et al., 2006)wing stroke (Yang et al., 2006)

Page 9: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

9

Aim 2Aim 2

Effect of MV on stretch Effect of MV on stretch reflexreflex– The contribution of spinal The contribution of spinal

pathways on vibration-pathways on vibration-induced changes in motor induced changes in motor evoked potentials is not evoked potentials is not clear. clear.

Result:Result:– The amplitude of M1 was The amplitude of M1 was

depressed by vibration.depressed by vibration.– The spinal pathway did not The spinal pathway did not

provide the positive effects provide the positive effects on the increase of MEP.on the increase of MEP.

Ia Inhibition

Afferent

Stretch

Vibration

Efferent

1. M1↓2. M2 =

Spinalcord

Brain +

SLSR Peak Amplitude (n=10)

0

50

100

150

200

FDI APB ADM%

MV

C no MV

MV

*

Page 10: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

10

Aim 3Aim 3 Examine whether the Examine whether the

vibration-induced nevibration-induced neurophysiological modurophysiological modulations reflect in the ulations reflect in the voluntary control of fivoluntary control of finger movementsnger movements..

HypothesisHypothesis Muscle vibration to selecMuscle vibration to selec

tive hand muscle affects tive hand muscle affects muscle selectivity and finmuscle selectivity and finger independency in healger independency in healthy/stroke individuals.thy/stroke individuals.

Page 11: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

11

Aim 4Aim 4

Examine the effect of attended prolonged Examine the effect of attended prolonged muscle vibration on hand corticomotor excimuscle vibration on hand corticomotor excitability and control of finger movements. tability and control of finger movements.

Hypotheses:Hypotheses: prolong muscle vibration and subject’s attention prolong muscle vibration and subject’s attention

to vibration provide long-lasting effect on hand corto vibration provide long-lasting effect on hand corticomotor excitability.ticomotor excitability.

the long-lasting modulations of motor pathway exthe long-lasting modulations of motor pathway excitability also reflect on control of finger movemencitability also reflect on control of finger movements.ts.

Page 12: 實驗室簡介 Final

National Chiao Tung University, Taiwan

Integrated Smart Living Integrated Smart Living TechnologyTechnology

H-Y Hu, C-C Wang, S-W Chou, T-S Chen, H-Y Hu, C-C Wang, S-W Chou, T-S Chen, S-T Liao & Yi-Ting YangS-T Liao & Yi-Ting YangCollaborators: Brain Research Center, EE Collaborators: Brain Research Center, EE & CS Dept, NTHU, YMU, NCU…& CS Dept, NTHU, YMU, NCU…

Page 13: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

13

Force PlateForce Plate

Floor Floor Material Material

BB

Floor Floor Material Material

AA

Coefficient of FrictionCoefficient of Friction on Different Floor Surfaces on Different Floor Surfaces

Effects of Floor Transition Effects of Floor Transition on Gait Stabilityon Gait Stability

Adaptation on Adaptation on Different ConditionDifferent Condition

Appropriate Range of COF Appropriate Range of COF and Suitable Floor materialand Suitable Floor material

Effect of Floor Material Change Effect of Floor Material Change on Gait Stabilityon Gait Stability

Page 14: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

14

Effect of Floor Material Change Effect of Floor Material Change on Gait Stabilityon Gait Stability

Foot angle at heel strike would decrease, and lager peak RCOF was also observed.

Page 15: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

15

Real-Time Musculoskeletal Real-Time Musculoskeletal ModelingModeling

Page 16: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

16

Movement Classifier Using Movement Classifier Using Inertial Sensors & EMGInertial Sensors & EMG

Page 17: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

17

Movement Classifier Using Movement Classifier Using Inertial Sensors & EMGInertial Sensors & EMG

Fall occurs at Fall occurs at 1.8s1.8s

EMG EMG

Motion capture

Page 18: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

18

BiometricsBiometrics

Kinetics

Neural Network (Self-Organizing map)

Kinematics Plantar Pressure

Person Recognition

Offering biomechanical point of view for computer science and electronics communitiesReducing computing timeFinding other movement features of human gait that co

uld provide good recognition rate

Page 19: 實驗室簡介 Final

National Chiao Tung University, Taiwan

Light weight vehicle for Light weight vehicle for the elderlythe elderly

S-W Chou, T-S Chen, S-T Liao, & S-T WuS-W Chou, T-S Chen, S-T Liao, & S-T WuCollaborator: Collaborator: National Taipei University of National Taipei University of Technology Technology

Page 20: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

20

Wheelchair or Scooter Foldable seat

Older user – centered designOlder user – centered design

Dynamic controlUser’s needs

Ergonomics

Suspension system Light weight structure

Solar energy A/C

User safety design

Egress/Ingress safetyDynamic driving safetyUser’s physiological status monitoring

Page 21: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

21

Experimental platformExperimental platform

Page 22: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

22

Experimental setupExperimental setup

Page 23: 實驗室簡介 Final

biomechanics biomechanics && medical application lab medical application labNational Chiao Tung University, Taiwan Bing-Shiang YangBing-Shiang Yang, ,

Ph.D., P.E.Ph.D., P.E.

23

Musculoskeletal modelingMusculoskeletal modeling

Page 24: 實驗室簡介 Final

National Chiao Tung University, Taiwan

Biomechanics and Biomechanics and Medical Application Medical Application

LaboratoryLaboratory

Bing-Shiang Yang, Ph.D., P.EBing-Shiang Yang, Ph.D., P.EDepartment of Mechanical EngineerinDepartment of Mechanical Engineeringg