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2013 年全国高分子论文报告会
主题 Q 中美高分子材料前沿论坛
Frontiers in Polymeric Materials
The 3rd ACS-PMSE/CCS-PD Joint Symposium
Oct. 15, 2013, Shanghai Expo Center
Program
Room 620, EXPO Center
Oct. 15, 2013
8:30-8:40 Introductory Remarks
8:40-10:10 Host: Ben Zhong Tang
8:40-9:10 R. D. Miller Nanogel Star Polymers as Interesting Soft
Colloid Materials for Biomedical Applications: No Assembly Required
9:10-9:40 Zhibo Li From alpha-Amino Acid to Functional Polypeptide Materials
9:40-10:10 D. A. Savin
Interfacial Curvature Effects in the Self-Assembly and Responsiveness in Polypeptide-Based Star and Triblock
Copolymers
10:10-10:30 Group Photo & Tea Break
10:30-12:00 Host: R. D. Miller
10:30-11:00 Ben Zhong
Tang Functional Macromolecules Constructed
from Triple-Bond Building Blocks
11:00-11:30 D. C. Martin
Functionalized EDOT and ProDOT Thiophene Copolymers for Interfacing
Electronic Biomedical Devices with Living Tissue
11:30-12:00 Yanhou Geng
Conjugated Polymers Based on Dithienocarbazoles
12:00-13:00 Lunch
13:00-15:00 Poster Session
15:00-16:30 Host: Jun Wang
15:00-15:30 S. Z. D. Cheng Molecular Nanoparticles Are
Unique Elements for Macromolecular Science
15:30-16:00 Yuguo Ma Reaction under Pressure: The
Role of Noncovalent Interactions
16:00-16:30 C. W. Bielawski Polymer Mechanochemistry:
Using Force to Direct Chemical Reactivity
16:30-16:50 Tea Break
16:50-18:30 Host: S. Z. D. Cheng
16:50-17:20 Jun Wang Differential Drug Delivery with Bacterial-Responsive Polymeric
Nanoparticles
17:20-17:50 L. T. J. Korley Combining Forced Assembly and
Self-Assembly in Extruded Multilayer Films
17:50-18:20 Yanlei Yu Photocontrollable Liquid Crystalline Polymer Actuators
18:20-18:30 Closing Remarks
Speakers & Abstracts
Dr. Robert D. Miller
IBM Almaden Research Center
Robert D. Miller received his PhD in Organic Chemistry from Cornell University
and spent a postdoctoral year at Union Carbide Research Institute in Tarrytown NY
working on flash vacuum pyrolysis and matrix isolation spectroscopy of reactive
intermediates. He joined IBM at the T. J. Watson Research Laboratories in Yorktown
Heights NY after his postdoctoral year and moved to the San Jose Research
laboratory. He has served in a number of technical management positions at the IBM
Almaden Research Laboratory in San Jose. His research activities have included:
basic photochemical processes and mechanisms, radiation sensitive polymers and
microlithography, synthetic methods utilizing multifunctional synthons, synthetic
applications of strained ring materials, spectroscopy and chemistry of reactive
intermediates, new polymeric materials for nonlinear optics, polymeric light emitting
diodes, novel polymeric architectures, silicon and germanium containing polymers,
controlled polymerization techniques, functionalized organic and inorganic
nanoparticles, materials for molecular and organic electronics, organic materials for
magnetic storage, polymeric electronic materials for semiconductor applications,
nanoporous thin films for Bioscience, Optics and Photonics, photovoltaic materials
and structures, sublithographic self-assembly using block copolymers, air bridge
dielectrics, radiation definable dielectrics, solution and CVD precursors for low-k
applications, and others. He is a member of the American Chemical Society and the
Materials Research Society and currently serves on the editorial advisory boards of
Chemical Reviews and Advanced Functional Materials. During his career, he has
received five IBM awards for outstanding technical achievements and 39 invention
plateau awards, and is designated an IBM Master Inventor and is a member of the
IBM Academy of Technology. Dr. Miller was elected a Fellow of the Division of
Polymeric Materials Science and Engineering (PMSE) in 2006, the Materials
Research Society (MRS) in 2007 and the American Chemical Society in 2010. In
2009, he was elected to the National Academy of Engineering and is the recipient of
the 2010 American Chemical Society award for Chemistry of Materials. Dr. Miller is
a co-inventor on more than 100 patents and patent publications and has published
more than 350 articles in refereed technical journals.
Nanogel star polymers as interesting soft colloid materials for
biomedical applications: No assembly required
R. D. Miller
IBM Almaden Research Center, San Jose CA 95120
Polymers have numerous biomedical applications including delivery of therapeutic
materials, imaging applications, tissue regeneration, antimicrobial action and others.
We have developed a route to nanogel core star polymer amphiphiles with control
over size, arm number, functionality, end groups and molecular architecture. Variants
of these materials were originally developed to serve as sacrificial pore generators
for low-k applications. More recently, we have been focusing on potential
biomedical applications. For these, the particles can either be biostable or
biodegradable depending on the incorporated functionality and the desired
application. With appropriate functionality, the nanogel stars can also be assembled
in layer-by-layer processes both with and without cargos. These materials
spontaneously encapsulate hydrophobic materials such as dyes and therapeutics at
the 10-15% level without covalent bonding. The ligands in the outer shell also
sequester magnetic particles for MRI studies and ligate ions such as copper 64 for
PET. The outer shell can also serve as a catalytic surface to generate a functional
silica shell or initiate the electroless deposition of a gold shell. This can occur either
on a surface or on the individual particles in solution. The later leads to a surface
plasmon resonance absorption shifted into the near IR suitable for inducing
hyperthermic processes in cells upon irradiation. We have also studied the
antimicrobial properties of suitable substituted nanogel star polymers derivatives
when deposited on surfaces. I will discuss the synthesis, characterization and
applications of nanogel stars polymers in this lecture.
Prof. Dr. Zhibo Li
Institute of Chemistry, Chinese Academy of Sciences
Prof. Zhibo Li is a professor in the Laboratory of Polymer Physics and Chemistry at the Institute of
Chemistry, Chinese Academy of Sciences, Beijing, China. He received his B.S. and M.S. degrees
in polymer chemistry from the University of Science and Technology of China (USTC) in 1998
and 2001, respectively. He then came to the U.S. to pursue his Ph.D. degree in the Department of
Chemistry at the University of Minnesota under the supervision of Professors Timothy P. Lodge
and Prof. Marc A. Hillmyer. After completing his dissertation defense in 2006, Dr. Li joined
Professor Timothy J. Deming’s laboratory in the Department of Bioengineering at the University of
California, Los Angles as a postdoctoral researcher. He started his independent scientific career at
the Institute of Chemistry, Chinese Academy of Sciences in later 2008.
Our current research focuses on the design, synthesis and applications of functional
polypeptide materials. Starting with natural amino acid, we introduce additional functional groups
to obtain thermal responsive polypeptides, from which we can construct stimuli-responsive
polypeptide materials. Using these thermal responsive polypeptides as building blocks, we can
construct fully biodegradable and biocompatible drug delivery system and thermal responsive
hydrogel. On the other hand, we are interested using polypeptide as synthetic template to make
non-spherical polymer grafted silica nanoparticle via biomimetic strategy.
From alpha-Amino Acid to Functional Polypeptide Materials
Zhibo Li
Laboratory of Polymer Physics and Chemistry, Institute of Chemistry
Chinese Academy of Sciences, Beijing, China,
Stimuli-responsive polymers are termed smart materials and have extensive
applications in bio- and nanotechnology. Meanwhile, many well studied
thermo-responsive polymers had some limitations regarding their biocompatibility
and biodegradability for in vivo applications. Hence, fully biodegradable responsive
biopolymers are greatly desirable for biomedical applications. We developed a new
synthetic strategy to prepare thermo-responsive polypeptides. The obtained
polypeptides display low critical solution temperature (LCST) behaviors in water,
and the LCST can be tuned via copolymerization of different amino acid monomers
at varied molar ratio. Their study was believed to be the first example of
thermo-responsive helical polypeptide made from ring-opening polymerization of
-amino acid N-carboxy-anhydrides (NCAs).
Furthermore, we prepared three alkyl-polypeptide (AP) amphiphiles using alkyl
amine as initiator via ring-opening polymerization (ROP) of -amino acid
N-carboxyanhydride (NCA). The polypeptide segment was composed of diethylene
glycol monomethyl ether functionalized poly-L-glutamate (poly-L-EG2Glu). These
AP amphiphiles can spontaneously self-assemble into transparent hydrogels in water.
These hydrogels showed shear thinning properties, and their strength can be
modulated by hydrophobic alkyl tails. CryoTEM and AFM characterizations
suggested these hydrogels were formed by nanoribbons arising from intermolecular
interactions between nonionic poly-L-EG2Glu segments.
Scheme 1. Illustration of thermal responsive peglated poly-L-glutamate
polyEG1Glu
polyEG2GlupolyEG3Glu
polyEG1Glu
polyEG2GlupolyEG3Glu
polyEG1Glu
polyEG2GlupolyEG3Glu
Prof. Dr. Daniel A. Savin
The University of Southern Mississippi
Prof. Savin received a BS in chemistry from Harvey Mudd College in 1995 and a
PhD in chemistry with Prof. Gary Patterson at Carnegie Mellon University in
2002. After a postdoctoral position with Prof. Timothy Lodge at the University of
Minnesota, he began his independent career at the University of Vermont. He
joined the School of Polymers and High Performance Materials at the University of
Southern Mississippi in 2008. Research in the Savin group is focused in three
primary areas: self-assembly and responsiveness of topologically complex
peptide-based block copolymers, energy damping nanocomposites, and polymers in
energy and environmental applications.
Interfacial curvature effects in the self-assembly and
responsiveness in polypeptide-based star and triblock
copolymers
Jacob G. Ray, Ashley J Johnson, Greg Strange, Daniel A. Savin
School of Polymer and High Perfoemance Materials,
The Univ. of Southern Mississippi
This study involves the bottom-up design and tunability of responsive, peptide-based
block copolymers. The self-assembly of amphiphilic block copolymers is dictated
primarily by the balance between the hydrophobic core volume and the hydrophilic
corona. In these studies, amphiphilic triblock and star copolymers containing
poly(lysine) (PK) and poly(glutamic acid) (PE) were synthesized and their solution
properties studied using dynamic light scattering, circular dichroism spectroscopy
and transmission electron microscopy. These materials exhibit hydrodynamic size
that is responsive to pH, due in part to the helix-coil transition in the peptide chain,
but also due to changes in curvature of the assembly at the interface. This talk will
present some recent studies in solution morphology transitions that occur in these
materials as a result of the helix-coil transition and associated charge-charge
interactions. We exploit the responsiveness of these materials to encapsulate and
release therapeutics such as doxorubicin and demonstrate the potential to achieve
triggered release as a function of pH due to morphology transitions.
Prof. Dr. Ben Zhong Tang
The Hong Kong University of Science & Technology
Ben Zhong Tang is Chair Professor in the Department of Chemistry and Division of
Biomedical Engineering at Hong Kong University of Scientific & Technology
(HKUST). He is also Stephen K. C. Cheong Professor of Science at HKUST and
honorary professor at South China University of Technology (SCUT). He received
BS degree from Department of Polymer Science and Engineering of SCUT in 1982
and Ph.D. degree from Kyoto University in 1988. He conducted postdoctoral
research at Toronto University and then joined HKUST in 1994. In 2009, he was
elected into the Chinese Academy of Sciences.
His research interests include exploration of new polymerization reactions, synthesis
of new functional (macro) molecules, decipherment of new luminescent processes,
creation of new advanced materials, and development of new fluorescent biosensors.
He has published more than 500 scientific papers, which have been cited by peers
over 10000 times, with an h-index of 73. He is the chief scientist of Key Project of
Chinese National Programs for Fundamental Research and Development (973
Program). He is currently Associate Editor of Polymer Chemistry and
Editor-in-Chief of RSC Polymer Chemistry Series. He has received a number of
awards and honors, including Croucher Senior Research Fellowship Award (Hong
Kong), State Natural Science Award (2nd Class; China), Macro2012 Lecture Award
(US), and Fellow of The Royal Society of Chemistry (UK).
Functional Macromolecules Constructed from Triple-Bond
Building Blocks
Ben Zhong Tang
Department of Chemistry, The Hong Kong University of Science & Technology,
Clear Water Bay, Kowloon, Hong Kong, China
Development of new methodologies for the construction of functional polymers with
novel structures and unique properties is of fundamental importance in polymer
science. Our research group has been actively working on the development of new
alkyne polymerization routes towards functional macromolecules. In this talk, I
will discuss our recent work on the exploration of new alkyne polymerization
reactions. These reactions include alkyne polycyclotrimerization, alkyne–azide
“click” polymerization, palladium-catalyzed coupling of terminal alkynes and
aroyl chlorides, rhodium-catalyzed decarbonylative polyaddition of aroyl chlorides
and alkynes, rhodium-catalyzed oxidative coupling of internal diynes with either
arylboronic acids or phenylpyrazoles, and rhodium-catalyzed hydrosilylation or
hydrothiolation of alkynes. Furthermore, we studied three-component reactions
including polycouplings among aroyl chlorides, alkynes, and boron trichlorides,
indium-catalyzed polycoupling of alkyne, aldehyde, and secondary amine, cuprous
chloride-catalyzed polycoupling of alkynes, aldehydes and amino acids.
Three-component tandem reactions including palladium-catalyzed polymerization of
terminal alkynes, aroyl chlorides and either thiols or amines can generate
well-defined sequence-ordered polymers with easily tunable polymer backbones.
Our recent work has significantly expanded the scope of alkyne polymerizations and
endows the polymers with various topological structures and unique properties
including macroscopic processability, thermal stability, light refractivity, optical
nonlinearity, chiroptical activity, and light emission. The potential high-tech
applications of the functional polymers are explored in the areas of chemical sensing,
biological imaging, fluorescent photopatterning, precursors for magnetic ceramics,
etc.
Prof. Dr. David C. Martin
The University of Delaware
Prof. David C. Martin is the Karl W. and Renate Böer Professor and Chair of
Materials Science and Engineering and Professor of Biomedical Engineering at the
University of Delaware. His research interests include the design, synthesis, and
characterization of conducting polymer coatings for integrating electronic biomedical
devices in living tissue, high-resolution microscopy and impedance spectroscopy
studies of defects in ordered polymers and organic semiconductors, and the
deformation behavior of crystalline polymer and organic molecular materials near
surfaces. His research has been supported by the National Science Foundation, the
Defense Advanced Research Projects Agency, the Army Research Office, and the
National Institutes of Health. Before 2009 Prof. Martin was Professor of Materials
Science and Engineering, Biomedical Engineering, and Macromolecular Science and
Engineering at the University of Michigan in Ann Arbor, MI, and is a Co-Founder
and Chief Scientific Officer for Biotectix LLC of Quincy, MA. He is currently
Chair of the Division of Polymeric Materials Science and Engineering Division of
the American Chemical Society. He is a Fellow of the American Institute for
Medical and Biological Engineering, the American Physical Society, and was an
Alexander von Humboldt Fellow at the Max-Planck Institute for Polymer Research
in Mainz, Germany from 1997-1998. Before arriving at Michigan, Prof. Martin
worked on polyimide morphology with Kenn Gardner and Larry Berger at DuPont
Central Research & Development in Wilmington, DE. Prof. Martin received his Ph.D.
in 1990 in Polymer Science and Engineering from the University of Massachusetts at
Amherst under the direction of Prof. Edwin L. Thomas, who is now the Dean of
Engineering at Rice University. Prof. Martin has held previous positions at the
General Motors Research Center in Warren, MI; at IBM General Technology
Division in Burlington, VT; and at GE Carboloy Systems Division in Detroit, MI.
Functionalized EDOT and ProDOT Thiophene Copolymers
for Interfacing Electronic Biomedical Devices with Living
Tissue
David C. Martin
Materials Science and Engineering, The University of Delaware
We continue to be interested in the development of conjugated organic polymers and
copolymers for interfacing a variety of hard, inorganic metallic and semiconductor,
engineered electronic biomedical devices with ionically-conducting, soft, living
neural and muscular tissue. Current examples of these devices include cardiac
pacemakers, cochlear implants, retinal implants, peripheral nerve interfaces, and
cortical microelectrodes. Recently we have been designing, synthesizing, and
characterizing the properties of chemicall-functionalized versions of the
3,4-ethylenedioxythiophene (EDOT) and 3,4-propylenedioxythiophene (ProDOT)
monomers. Examples of these monomers include carboxylic-acid functionalized
EDOT (EDOT-acid), and thiol-ene functionalized ProDOT. We are also
investigating branched variants of both EDOT and ProDOT to improve mechanical
properties through crosslinking. These new monomers require variations in the
electrochemical deposition conditions, including alternative choices for solvents and
counter-ions. We have characterized the resulting PEDOT and P(ProDOT)
polymers and copolymers using a variety of techniques including optical and
electron microscopy, X-ray diffraction, electrochemical impedance spectroscopy, and
biological activity assays. These new materials make it possible for us to
systematically tailor the stiffness and toughness of the films, their adhesion to solid
substrates, their charge transport properties, their wetting behavior, and their specific
interactions with cells.
Prof. Dr. Yanhou Geng
Changchun Institute of Applied Chemistry
Chinese Academy of Sciences
Yanhou Geng joined Changchun Institute of Applied Chemistry (CIAC), Chinese
Academy of Sciences (CAS) in August 2013 as a Professor in the State Key
Laboratory of Polymer Physics and Chemistry. He was graduated from Department
of Applied Chemistry, Shanghai Jiao-Tong University in 1991, and obtained Ph.D.
degree of Polymer Chemistry and Physics in CIAC, CAS in 1996. After then he had
been research associate in CIAC until 1998. He was honored the Alexander von
Humboldt research fellow in 1998 and had been working in the Max-Planck Institute
for Polymer Research in Mainz, Germany from 1998 to 2000. Then, he moved to the
Department of Chemical Engineering, University of Rochester, USA, and had been a
postdoctoral researcher till back to CIAC.His current research interests include:
design and synthesis of high performance organic semiconductors; controlled
polymerization for the synthesis of conjugated polymers, monodisperse conjugated
oligomers/polymers and their self-assembly properties; chemistry of fused aromatics
and related optoelectronic materials. He has published over 130 papers in
peer-reviewed journals, and was issued over 20 patents. He was awarded by
“National Science Fund for Distinguished Young Scholars” in 2005 and National
Natural Science Award of China (second prize) in 2009.
Conjugated Polymers Based on Dithienocarbazoles
Yanhou Geng
State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of
Applied Chemistry, Chinese Academy of Sciences
One of the strategies for designing high performance polymeric semiconductors is to
incorporate heteroacenes into conjugated polymer backbone to enhance the
coplanarity and thus the intermolecular interaction. However, the solubility of CPs
will decrease dramatically when large heteroacenes are employed. To overcome this
problem, we synthesized two new heteroacenes based on carbazole unit, i.e.
dithieno[2,3-b;7,6-b]carbazole (DTC1) and dithieno[3,2-b:6,7-b]carbazole (DTC2),
in which a alkyl chain can be introduced at N atom. Their copolymers with
bithiophene, diketopyrrolopyrrole (DPP) and thienopyrroledione (TPD) were
synthesized by Stille coupling. Bottom gate and top contact organic thin films
transistors (OTFTs) and bulk heterojunction solar cells (PSCs) were fabricated to
study the effect of molecular structures on charge transporting and photovoltaic
properties. The highest mobility of 1.36 cm2/V·s for OTFTs and power conversion
efficiency of 8.0% for PSCs have been demonstrated.
Prof. Dr. Stephen Z. D. Cheng
The University of Akron, Akron
Cheng received his Bachelor's degree in mathematics from the East China Normal
University in Shanghai in 1977. Cheng received his MSc in polymer science &
engineering from the Donghua University also in Shanghai in 1981.[1] Cheng further
pursued his study in the United States. He became a graduate student at the
Rensselaer Polytechnic Institute in 1981, and obtained his PhD degree in Polymer
Chemistry in May 1985. Cheng became a faculty as an assistant professor of polymer
science at the University of Akron in October 1987. He was promoted to associate
professor with tenure in 1991, and further the professor of polymer science in 1995.
Cheng became the Trustees Professor of Polymer Science in September 1998, and
the Robert C. Musson Professor of Polymer Science in 2001, all at the University of
Akron. From 2001 to 2005, Cheng was the Chairman of the Department of Polymer
Science at the University of Akron, and he was appointed Dean of the College of
Polymer Science & Polymer Engineering on August 1, 2007. Cheng has been
awarded, The Presidential Young Investigator Award, by the White House and the
National Science Foundation (1991), The ACS Akron Section Award (1994), The
John H. Dillon Medal (1995), The Mettler-Toledo Award (1999), The TA-Instrument
Award (2004), The Cooperative Research Award (2005), Polymer Physics Prize
(2013). Cheng was elected Fellow of the American Association for the Advancement
of Science in 2006, Fellow of the American Physical Society in 1994, Fellow of the
North American Thermal Analysis Society in 1992, Fellow of the American
Chemical Society in 2012. In 2008, Cheng was elected Member of the United States
National Academy of Engineering and 2011 he was elected Member of the National
Academy of Inventors.
Molecular Nanoparticles Are Unique Elements for
Macromolecular Science
Stephen Z. D. Cheng
College of Polymer Science and Polymer Engineering,
The University of Akron, Akron, Ohio 44325-3909
Constructing hieratical structures across different length scales is central to the
design of novel materials with controlled and predicted macroscopic properties. We
have introduced a new class of self-assembling hybrid materials, which are built
upon shape- and volume-persistent molecular nanoparticles (MNPs) and other
structural motifs such as polymers, dendramers, and can be viewed as a
size-amplified version of the corresponding small-molecule counterparts:
“nano-atoms”. Giant molecules are constructed by these “nano-atoms”. Among the
different categories of giant molecules, “giant surfactants” with precise molecular
structures have been designed and synthesized via “clicking” compact and polar
MNPs with polymer tails of various composition and topological architecture at
specific sites. Capturing the structural features of small-molecule surfactants but
possessing much larger sizes, giant surfactants bridge the gap between
small-molecule surfactants and block copolymers, and demonstrate a duality of both
materials in terms of their self-assembly behaviors. Another category of giant
molecules is shape amphiphiles and polyhedral. The controlled structural variations
of these giant molecules through precision synthesis reveal that their self-assemblies
are remarkably sensitive to primary chemical structures, leading to highly diverse,
thermodynamically stable nanostructures. These structures possess feature sizes
around 10 nm or smaller in the bulk, thin film, and solution states. The construction
of those nano-structures is relying on and dictated by the collective physical
interactions and geometric constraints. The results suggest that this class of hybrid
materials provides a versatile platform that is not only scientifically intriguing, but
also technologically important.
Prof. Dr. Yuguo Ma
Peking University
Prof. Yuguo Ma obtained his B.Sc. degree with honor in 1994 and a Master degree in
1997 from College of Chemistry at Peking University. His research work was on
liquid crystalline polymers under supervision of Prof. Qi-Feng Zhou. He continued
his graduate study in the Department of Chemistry at University of Illinois at
Urbana-Champaign with Prof. Steven C. Zimmerman, and obtained his Ph.D. in
Organic/Polymer Chemistry in December 2002. From January 2003 to August 2005,
he was a postdoc research associate with Prof. Geoffrey W. Coates in the Department
of Chemistry and Chemical Biology of Cornell University. The main focus of his
postdoctoral work was on organometallic chemistry and catalysis. In September
2005, he returned to Peking University as an Associate Professor in the Department
of Polymer Science and Engineering at College of Chemistry. In 2008, he was
selected to be in “Program of Excellent Talents for New Century” by the Ministry
of Education. He was promoted to full Professor in 2011.
Prof. Ma’s research interest includes: Supramolecular Chemistry; Molecular
Recognition and Self-Assembly; Organic Functional Materials based on Dendrimers;
Organometallic Catalysis; etc.
Reaction under Pressure: The Role of Noncovalent
Interactions
Yuguo Ma
Key Lab of Polymer Chemistry & Physics of Ministry of Education,
College of Chemistry, Peking University
Controlled cycloaddition reactions mediated by noncovalent interactions have great
potential in syntheses, especially in organic syntheses in solid state. Advantages of
such reactions include high yield, convenient work up and “green” process. We
have demonstrated a copper-free 1,3-dipolar cycloaddition of azide and alkyne at
room temperature in the solid state. Crystal packing facilitated by
arene-perfluoroarene interactions offered a desirable spatial arrangement of the azide
and alkyne functional groups, and therefore promoted a relatively well-controlled
regioselective “ click ” polymerization. Then, we continued to design a
supramolecular system to pre-organize azide and alkyne functional groups in
crystalline state via electrostatic and arene-perfluoroarene interactions. After
pre-organization, high pressure was applied to accelerate the cycloaddition of azide
and alkyne. The position of reacting functional groups were suitable to generate
1,4-disubstituted triazole and therefore promoted a regioselective cycloaddition. This
is a good example of pressure-accelerated reaction with high regioselectivity resulted
from suitable packing through two non-covalent interactions cooperatively. Most
recently, we reported a rapid preparation of a unique sandwich-like charge transfer
(CT) complex from electron rich anthracene and electron deficient
5,6,7,8-tetrafluoro-1,4-anthraquinone, either through a solution process within
seconds or solid state mechanical grinding of the binary mixture for several minutes.
CT complex formation inhibits the Diels-Alder reaction in the crystalline state,
which was a rare report in such cycloaddition reactions.
Prof. Dr. Christopher W. Bielawski
University of Texas at Austin
Christopher W. Bielawski is a Professor in the Department of Chemistry and
Biochemistry at the University of Texas at Austin. He holds degrees from the
University of Illinois at Urbana-Champaign (B.S., 1997) and the California Institute
of Technology (Ph.D., 2003). Prof. Bielawski's research program lies at the interface
of polymer science and materials chemistry, and focuses on the synthesis and study
of unique organic and organometallic macromolecules. His contributions to research
and education have been recognized with a National Science Foundation CAREER
Award, an Alfred P. Sloan Research Fellowship, Young Investigator Awards from the
Beckman Foundation and the Office of Naval Research, a Camille Dreyfus
Teacher-Scholar Award, a Research Corporation Cottrell Scholar Award, and a
Presidential Early Career Award for Scientists and Engineers (PECASE).
Polymer Mechanochemistry: using force to direct
CHEMICAL reactivity
Christopher W. Bielawski
Department of Chemistry and Biochemistry
University of Texas at Austin
Mechanochemistry, whereby chemical transformations are facilitated using
mechanical force, often induces reactivity that is otherwise inaccessible. In this
presentation, we will describe how exogenous forces have been used to surmount
thermally-inaccessible isomerization barriers, facilitate retro-cycloadditions, and
activate latent coupling or polymerization catalysts. In general, these transformations
were facilitated through the site-specific activation of mechanophores – or
chemical moieties designed to respond to mechanical force in a predictable manner
– embedded within high molecular weight polymer chains. Included in the
discussion will be a series of extensive spectroscopic analyses and control
experiments that demonstrated the aforementioned activation processes originated
from forces generated under ultrasound. Finally, some perspectives on the use of
mechanical force to enable novel reactivity will be discussed.
Prof. Dr. Jun Wang
University of Science and Technology of China
Dr. Jun Wang is a professor of Life Sciences and Polymer Chemistry of University of
Science and Technology of China (USTC), an adjunct professor of Hefei National
Laboratory for Physical Sciences at the Microscale and Medical Center of USTC. He
received his B.Sc. degree in Chemistry and Cell Biology in 1993 and a Ph.D. degree
in Polymer Chemistry and Physics in 1999 from Wuhan University. From 1999 to
2004, he worked as a postdoctoral fellow at Johns Hopkins Singapore and Johns
Hopkins School of Medicine. In 2004, he joined the faculty of USTC as a full
professor. His main research interests cover polymeric biomaterials, novel drug
delivery systems and nanomedicine. He published ~100 peer-reviewed papers and 6
authorized Chinese patents. Currently, and he has been served as an Editorial Board
Member of Biomaterials Science, a member of Chinese Society for Biomaterials,
Chinese Chemical Society CCS Division of Chemical Biology and Chinese
Micro/Nano Technology Society. He received the Capsugel Innovation Award from
the Controlled Release Society in 2001. He was the awardee of “One Hundred
Talents” of Chinese Academy of Science in 2005 and received “Outstanding Young
Scholar Award” of National Science Foundation of China in 2011. In 2013, he
received the First prize of Natural Science Award of the Ministry of Education of
China.
Differential Drug Delivery with Bacterial-Responsive
Polymeric Nanoparticles
Jun Wang
Hefei National Laboratory for Physical Sciences at the Microscale and School of
Life Sciences
University of Science and Technology of China
Nanoparticles that are responsive to the unique microenvironment of lesion sites
have attracted widespread attention in drug delivery. Herein, we report a new
strategy for differential drug delivery to bacterial infection sites through the
development of bacterial-responsive polymeric nanoparticles. With a convenient
“arm first” procedure via one-step ring-opening polymerization, we developed a
lipase-sensitive polymeric triple-layered and polyphosphoester core-crosslinked
nanogel. This triple-layered nanogel (TLN) contained a lipase-sensitive poly(ε-caprolactone) (PCL) interlayer between the cross-linked polyphosphoester core and
the shell of poly(ethylene glycol). The PCL segment formed a hydrophobic and
compact molecular fence in aqueous solution which prevented drug release from the
polyphosphoester core prior to reaching bacterial infection sites. However, once the
TLN sensed the lipase-secreting bacteria, the PCL fence of the TLN degraded to
release the encapsulated drug molecules. The nanogel has been successfully used for
the treatment of infection caused by bacteria, and for differential anti-cancer drug
delivery to bacteria-accumulated tumor artificial environment.
Prof. Dr. LaShanda T. J. Korley
Case Western Reserve University
LaShanda T.J. Korley joined the faculty of Case Western Reserve University (CWRU)
in July 2007 as an Assistant Professor in the Department of Macromolecular Science
and Engineering and was appointed to the Nord Distinguished Assistant
Professorship in July 2009 and the Climo Assistant Professorship in 2012.
LaShanda Korley earned a B.S. in Chemistry and Engineering from Clark Atlanta
University and a B.S. in Chemical Engineering from Georgia Institute of Technology
in 1999 as an ACS Scholar. Dr. Korley completed her doctoral studies at
Massachusetts Institute of Technology in the Department Chemical Engineering and
the Program in Polymer Science and Technology in 2005. LaShanda Korley was
the recipient of the Provost’s Academic Diversity Postdoctoral Fellowship at Cornell
University, where she completed a two-year postdoctoral appointment.
Her research focuses on the development of mechanically-enhanced, multifunctional
polymeric materials for a myriad of applications, including energy and sustainability,
biomedical engineering, protective fabrics, and structural materials. She is the
Leader of the Science and Technology Innovations Platform within the NSF Center
for Layered Polymeric Systems (CLiPS). Dr. Korley’s research efforts have been
recognized by a National Science Foundation (NSF) CAREER Award, NSF BRIGE
Award, a 3M Nontenured Faculty Grant, and a DuPont Young Professor Award. In
2012, Prof. Korley participated in the Japanese/American Frontiers of Science
Symposium as a Kavli Fellow and the National Academy of Engineering’s U.S.
Frontiers of Engineering Symposium. She was recently nominated (1 of 6
internationally) for the Young Talent Award, Polymers for Advanced Technologies
Congress 2013.
Combining forced assembly and self-assembly in extruded
multilayer films
LaShanda T. J. Korley
Department of Macromolecular Science and Engineering
Case Western Reserve University
Forced assembly via layer multiplication offers the unique opportunity to directly
probe the relationship between structural development and deformation behavior
under confined conditions. Several polymeric materials have been investigated: 1) an
elastomeric block copolymer (BCP) layered against a rigid thermoplastic, 2) a
semicrystalline polymer layered with high glass transition temperature polymer, and
3) a dielectric multilayered films post-processed to achieve various crystal
orientations. Confinement of the cylindrical BCP systems extruded below the
order-disorder transition (ODT) resulted in a layer thickness-dependent shift from
crazing to shear banding under deformation due to a combination of microdomain
orientation, interfacial effects, and thin layer yielding. Microstructure development
of a spherical BCP processed above the ODT was shown to vary with confining layer
due to interfacial interactions and layer thickness. For the semicrystalline multilayer
films, the deformation behavior was observed to shift from axial alignment of the
crystalline fraction in the thicker layers to non-uniform mechanics and micronecking
mechanisms in the thinner layers. In the dielectric materials, we have shown that
various methods of post-processing influence crystallization phenomena and
mechanical response.
Prof. Dr. Yanlei Yu
Fudan University
Yanlei Yu is Professor in the Department of Materials Science at Fudan University.
She graduated in applied chemistry from Anhui University in 1993 and obtained her
Master’s degree in polymer chemistry and physics from the University of Science
and Technology of China in 1996. She gained her Doctoral degree in environmental
chemistry and engineering from Tokyo Institute of Technology and was promoted to
Full Professor at Fudan University in 2004. She obtained New Century Excellent
Talents Fund of the Ministry of Education (2004), Shanghai Shuguang Scholar
(2005), Shanghai Science and Technology Rising Star (2006), Distinguished Young
Scholars Award from the National Natural Science Foundation of China (NSFC)
(2012), etc. Her research interests focus on the development of photodeformable
smart materials and light-controllable interface materials with photosensitive
polymers and liquid crystal polymers. She has over 50 publications in the
peer-reviewed journals with more than 1500 citations, such as Nature, J. Am. Chem.
Soc., Angew. Chem. Int. Ed., Adv. Funct. Mater., etc.
Photocontrollable Liquid Crystalline Polymer Actuators
Yanlei Yu
Department of Materials Science,
Fudan University, Shanghai, China
By incorporating azobenzene groups into the crosslinked liquid crystal polymers
(CLCPs), large deformations such as contraction and bending have been induced by
UV light due to the photoisomerization of the azobenzene chromophores. Since light
is an ideal stimulus for it can be localized (in time and space), selective,
nondamaging, and allows for remote delivery of energy, photodeformable CLCPs
present an interesting opportunity to realize soft actuators in microscope applications.
Recently, we incorporated upconversion materials which absorb low-energy light and
convert it to higher-energy photons in UV and visible regions, into the CLCP films
and succeeded in generating fast bending of the resulting composite films upon
exposure to red light and near-infrared light. It would be interesting and significant to
develop photodeformable CLCPs which could be photo-regulated by such
low-energy light, since it is more environment-friendly and causes less damage.
主办单位：
中国化学会高分子学科委员会
Chinese Chemical Society-Polymer Division (CCS-PD)
美国化学会高分子材料委员会
American Chemical Society-Polymer Materials: Science and Engineering
(ACS-PMSE)
承办单位：
东华大学材料科学与工程学院
College of Material Science and Engineering, Donghua University
纤维材料改性国家重点实验室
State Key Laboratory for Modification of Chemical Fibers and Polymer
Materials
2013 年全国高分子论文报告会组织委员会
顾 问：程镕时，黄志镗，沈家骢，沈之荃，徐 僖，郁铭芳，卓仁禧
主 任：周其凤
副主任：董建华,王笃金,徐 坚
委 员：安立佳，蔡小平，蔡远利，曹少魁，曹 镛，陈祥宝，陈学思，
陈义旺，陈永明，董建华，端小平，方世壁，冯圣玉，傅 强，
甘志华，高从堦，韩艳春，胡 杰，胡文兵，黄 维，黄险波，
黄玉东，江 雷，江 明，蒋士成，李 杨，李子臣，林嘉平，
刘良炎，刘世勇，刘正平，路庆华，马 劲，马建标，毛炳权，
钱家盛，乔金樑，沈一丁，史林启，孙晋良，唐本忠，王笃金，
王佛松，王俊景，王利祥，王 锐，王献红，王晓光，王玉庆，
王玉忠，吴 奇，夏延致，解孝林，谢续明，徐 坚，许家瑞，
徐志康，严 庆，颜德岳，杨 柏，杨万泰，杨玉良，杨振忠，
张俐娜，张建春，张 希， 张先正，赵东元，郑 强，周其凤，
朱美芳，朱秀林 （按姓氏汉语拼音为序）
会议秘书处
秘书长：朱美芳
副秘书长：余木火，王华平，张清华
秘书人员：张耀鹏，叶益红，杨曙光，蔡正国，江晓泽
主题 Q 中美高分子材料前沿论坛
Frontiers in Polymeric Materials: The 3rd ACS-PMSE/CCS-PD Joint Symposium
论坛组织主席： 王笃金， 李子臣， 朱美芳
秘书：杨曙光
材料科学与工程学院简介
东华大学材料科学与工程学院发源于 1954 年钱宝钧和方柏容教授创建的
新中国第一个化学纤维专业，历经化学纤维系、化学纤维研究所、高分子材料
系的发展阶段，于 1994 年成立。2002 年原国家轻工业部玻璃搪瓷研究所并入，
成为覆盖高分子和无机材料的研究型学院。
学院开设高分子材料与工程、无机非金属材料与工程、复合材料与工程以
及功能材料等四个本科专业，设有卓越班和理科试验班。拥有“材料科学与工
程”一级学科博士点、博士后流动站及“化学”理学博士点。建有三大国家和
省部级科研基地，分别为纤维材料改性国家重点实验室、高性能纤维教育部重
点实验室（B）和先进玻璃制造技术教育部工程研究中心。“材料学”为首批国
家重点学科，上海市十大重中之重学科，“材料加工工程”为上海市重点学科。
现有教职工 125 名，其中教授 42 名；在校生近 1700 多名，其中本科生 1000 名，
硕士研究生 480 名，博士研究生 231 名。自 1954 年建立专业以来，已培养毕业
生 13000 余名，遍布世界各地。
长期以来，学院在服务化学纤维工业升级改造中发挥着生力军作用。先后
攻克了功能共聚酯、细旦丙纶、纳米复合功能纤维、大容量聚酯直纺等一系列
行业共性基础问题与关键技术，为我国跃升为世界化纤生产第一大国做出了重
大贡献； 同时积极研发国防军工所需的战略性新材料， 特别是在高性能纤维
研制中取得重大突破和进展， 解决了碳纤维、高强高模聚乙烯纤维、芳香族聚
酰胺纤维等战略材料的有无问题，为我国迈入纤维强国奠定基础。先进玻璃材
料在神舟飞船上的成功应用显示了学院在无机材料研究方面形成了新的特色。
建设有特色、开放性、高水平的研究型学院是我们的发展目标。
COLLEGE OF MATERIALS SCIENCE AND
ENGINEERING
（CMSE）
CMSE in Donghua University, originated from the first major of chemical fibers in New China created by Prof. Qian Baojun and Prof. Fang Borong in 1954, was founded in 1994 after the development phases as Chemical Fiber Department, Institute of Chemical Fibers and Polymer Material Department. In 2002, the Glass and Enamel Institute affiliated with the former State Ministry of Light Industry immerged into CMSE. Currently, the College has four undergraduate disciplines, polymer, inorganic material, composite material, and functional material, and set up two classes of outstanding students, one is engineering and the other is natural science. The college has established PhD programs of materials and chemistry and the postdoc working station. In addition, 3 key laboratories anchor to the college: State Key Laboratory for Modification of Chemical Fibers and Polymer Materials; Key Laboratory of High-Performance Fibers & Products (B), Ministry of Education; Engineering Research Center of Advanced Glass Manufacturing Technology, Ministry of Education. Right now, the college has a staff of 125 people, including 42 full professors, and more 1700 students, 1000 undergraduate, 480 master and 231 doctor degree graduates. Since 1954, over 13,000 students have graduated and served in various areas.
For a long time, the college has taken the lead in upgrading and reforming the chemical fiber industry, successively dissolving the fundamental and the key technological problems in the industry and making contributions to uplifting China to be the biggest producer of chemical fibers. At the same time, the college has conducted research of strategic materials for national defense, and has achieved great breakthroughs in high-performance fibers, such as carbon, ultra-high molecular weight polyethylene, and Aramid fibers. The advanced glass material, which has been used by Shenzhou spaceship, demonstrates the college’s research capacity in the area of inorganic materials. Our aim is to establish the distinctive, embracive, high-level college and to be first-class education and research center.
纤维材料改性国家重点实验室简介
纤维材料改性国家重点实验室依托于东华大学，源于我国第一个化学纤维
专业，于 1992 年由国家计委批准筹建，1996 年通过国家验收，2003、2008 和
2013 年三次通过国家评估，是我国纺织和材料领域重要的国家级科研基地，为
我国发展成为化学纤维生产大国，并向纤维强国迈进作出重要贡献。目前设有
三个研究方向，分别为高性能纤维与复合材料、功能化纤维与低维材料、环境
友好和生物纤维材料。
实验室现有固定人员 50 余人，已形成一支知识和年龄结构合理，学术背景
和综合素质良好的高水平研究队伍。建有仪器设备公共平台，拥有大精测试仪
器 40 余台套，12 条工程试验线，实现 24 小时预约开放。
实验室始终坚持“开放、流动、联合、竞争”的八字方针。凝炼学科方向，
汇聚科研人才，严格规范管理，广泛开展交流与合作。近 5 年，共承担 973 计
划项目和课题、863 计划重大重点项目、国家科技支撑计划、国家自然基金重
大重点研究项目、国家杰出青年基金、省市部级和国际合作及企业合作项目等
900 余项，科研经费超近 3 亿元；先后荣获国家科技进步二等奖 8 项、省部级
科技进步一等奖 11 项、二等奖 23 项；发表学术研究论文 2400 余篇，其中 SCI
论文 800 余篇。申请专利 890 余项，授权发明专利 370 余项，
作为国家级科研基地，纤维材料改性国家重点实验室的发展目标是引领我
国纤维材料科学技术与产业发展，对接战略性新材料重大需求，成为国际一流
学术交流与研究基地。
STATE KEY LABORATORY FOR MODIFICATION OF
CHEMICAL FIBERS AND POLYMER MATERIALS
（SKLFPM）
SKLFPM, relying on Donghua University, was founded in 1992 on the approval
of State Planning Commission, and then passed the national ratification in 1996 and
appraisals in 2003, 2008 and 2013. As a state-level scientific research center of
textile and material in China, the lab has taken the leading role in reforming and
upgrading the traditional general chemical fiber industry, and making contributions
to uplifting China to be the biggest producer of chemical fibers and laying solid
foundation for China to march into the rank of fiber powers in the world. It currently
has three research themes, High performance fibers and composite materials,
Functional fibers and low-dimensional materials, and Environment friendly and
bio-compatible fiber materials. The lab has a faculty of 50 members, which
constitutes the research personnel with strong academic background and potential as
well as age and expertise diversity. The facility platform of the lab has more than 40
valuable high-accuracy instruments and 12 pilot processing lines, which are open 24
h for graduate students.
The lab persist the principle of ‘openness, mobility, cooperation and
competition’ to steer the research direction, attract the scientific talents, standardize
administration and implement extensive exchanges and cooperation. In past 5 years,
the lab has undertaken more than 900 scientific and engineering projects, including
National Basic Research Program (973 programs), Hi-Tech Research &
Development Program (863 programs), National Sci-Tech Supporting Plan, key
projects of NSFC, Distinguished Young Scientists Funding, and its total funding
revenue is about 300 million Yuan. The lab has won 8 second-prize awards in
National Scientific and Technological Progress Award, 11 first-prize awards and 23
second-prize awards in Provincial Scientific and Technological Progress Award. It
published about 2,400 academic articles, submitted 890 patent applications, and
obtained370 authorized patents.
SKLFPM aims to lead the development of fiber research and fiber industry, to
meet the great demand of the strategic fiber materials, and to be the international
first-class academic exchanges and research center.