a giant buschke-löwenstein tumor · a giant buschke-löwenstein tumor sara mai1*, salima baya2,...

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A Giant Buschke-Löwenstein Tumor Sara Mai 1* , Salima Baya 2 , Safae Maouni 1 , Kaoutar Znati 3 , Jawad Hafidi 2 , Abdellah Abbassi 2 , Karima Senouci 1 1 Department of Dermatology, University Hospital Ibn Sina, Rabat, Morocco 2 Department of Plastic Surgery, University Hospital Ibn Sina, Rabat, Morocco 3 Department of Histopathology, University Hospital Ibn Sina, Rabat, Morocco CLINICAL IMAGE A 70-year-old man with no notable medical history presented to our department with a huge tumor on his pubic area that had been evolving for over 20 years causing itching and foul smelling discharge. Physical examination revealed a cauliflower-like voluminous tumor on the patient’s pubis with extension to the penoscrotal area and the lower abdomen (Figure 1). A giant condyloma acuminate was suspected and extensive surgical excision was performed. Histopathological examination revealed hyperkeratosis, acanthosis, marked papillomatosis and koilocytes; confirming the diagnosis of Buschke-Löwenstein tumor (Figure 2). There were no features of malignant transformation. Figure 1: Voluminous tumour on the pubis and genitalia. Buschke-Löwenstein tumor or giant condyloma acuminatum is a rare sexually transmitted disease, caused by human papillomavirus; genotypes 6 and 11 in most cases. It’s incidence of about 0.1% in the general population, predominantly young men. Clinically it presents as a large, cauliflower-like tumor with papillomatous or verrucous surface. Radical excision of the entire lesion with histopathological examination of the whole lesions is recommended to confirm the diagnosis and detect a malignant transformation. Post-operative surveillance is necessary to identify potential recurrences. Figure 2: FUNDINGS Nil. CONFLICT OF INTEREST The authors declare that they have no competing interest. Jo u r n a l o f C l i n i c a l & E x p e r i m e n t al D e r m a t o l o g y R e s ea r c h ISSN: 2155-9554 Journal of Clinical & Experimental Dermatology Research Image Article Correspondence to: Sara Mai, Department of Dermatology, University Hospital Ibn Sina, Rabat, Morocco, Tel: +212625104836; E-mail: [email protected] Received: November 01, 2019; Accepted: November 14, 2019; Published: November 20, 2019 Citation: Mai S, Baya S, Maouni S, Znati K, Hafidi J, Abbassi A, et al (2019). A Giant Buschke-Löwenstein Tumor. J Clin Exp Dermatol Res. 10: 512. DOI: 10.35248/2155-9554.19.10.512 Copyright: © unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. J Clin Exp Dermatol Res, Vol.10 Iss.6 No:1000512 1 Histologic examination confirming the diagnosis of giant condyloma accuminata. 2019 Mai S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits

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Page 1: A Giant Buschke-Löwenstein Tumor · A Giant Buschke-Löwenstein Tumor Sara Mai1*, Salima Baya2, Safae Maouni1, Kaoutar Znati3, Jawad Hafidi2, Abdellah Abbassi2, Karima Senouci1 1Department

A Giant Buschke-Löwenstein Tumor

Sara Mai1*, Salima Baya2, Safae Maouni1 , Kaoutar Znati3, Jawad Hafidi2, Abdellah Abbassi2, KarimaSenouci1

1Department of Dermatology, University Hospital Ibn Sina, Rabat, Morocco

2Department of Plastic Surgery, University Hospital Ibn Sina, Rabat, Morocco

3Department of Histopathology, University Hospital Ibn Sina, Rabat, Morocco

CLINICAL IMAGE

A 70-year-old man with no notable medical history presented toour department with a huge tumor on his pubic area that hadbeen evolving for over 20 years causing itching and foul smellingdischarge. Physical examination revealed a cauliflower-likevoluminous tumor on the patient’s pubis with extension to thepenoscrotal area and the lower abdomen (Figure 1). A giantcondyloma acuminate was suspected and extensive surgicalexcision was performed. Histopathological examination revealedhyperkeratosis, acanthosis, marked papillomatosis andkoilocytes; confirming the diagnosis of Buschke-Löwensteintumor (Figure 2). There were no features of malignanttransformation.

Figure 1: Voluminous tumour on the pubis and genitalia.

Buschke-Löwenstein tumor or giant condyloma acuminatum is arare sexually transmitted disease, caused by humanpapillomavirus; genotypes 6 and 11 in most cases. It’s incidenceof about 0.1% in the general population, predominantly young

men. Clinically it presents as a large, cauliflower-like tumor withpapillomatous or verrucous surface. Radical excision of theentire lesion with histopathological examination of the wholelesions is recommended to confirm the diagnosis and detect amalignant transformation. Post-operative surveillance isnecessary to identify potential recurrences.

Figure 2:

FUNDINGS

Nil.

CONFLICT OF INTEREST

The authors declare that they have no competing interest.

Journal of

Clin

ical &

Experimental Dermatology Research

ISSN: 2155-9554

Journal of Clinical & ExperimentalDermatology Research Image Article

Correspondence to: Sara Mai, Department of Dermatology, University Hospital Ibn Sina, Rabat, Morocco, Tel: +212625104836; E-mail:[email protected]

Received: November 01, 2019; Accepted: November 14, 2019; Published: November 20, 2019

Citation: Mai S, Baya S, Maouni S, Znati K, Hafidi J, Abbassi A, et al (2019). A Giant Buschke-Löwenstein Tumor. J Clin Exp Dermatol Res. 10:512. DOI: 10.35248/2155-9554.19.10.512

Copyright: © unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

J Clin Exp Dermatol Res, Vol.10 Iss.6 No:1000512 1

Histologic examination confirming the diagnosis of giant

condyloma accuminata.

2019 Mai S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits