admission round: respiratory distress in newborn
DESCRIPTION
Admission Round: Respiratory Distress in Newborn (Case Study with Differential Diagnoses)TRANSCRIPT
Admission RoundExt. จริ�ยาภริณ์� พัฒนกุ�ลเล�ศExt. สาธิ�ญา ริตนส�นทวี�ส�ข
General Data
• ทาริกุแริกุเกุ�ดชายไทย• Date of Birth – 9 พั.ค. 2557, 3.39 น.• Age - 39 minutes after birth (4.15 น.)• ภ�มิ�ล!าเนา จ.เช�ยงริาย• CC: Tachypnea (RR 70/min)
Maternal History
• Mother was 32 y/o• G2P1A1L1• Monthly ANC 7 times at
another hospital– 1st ANC was GA 9+5, 12th
Nov 2013
• Anti-HIV: NR; HBsAg: Neg; VDRL: NR
• Blood type= O Rh +• No fever
• No intrapartum conditions, illnesses, or underlying diseases during pregnancy
• No history of smoking, alcohol, illicit drugs or any medication
Natal History
• Preterm (35 weeks)• C/S due to primibreech• PPROM of 4 hours• BW=2,200 gms (AGA)• APGAR=9,10,10• No resuscitation
Neonatal History
• ริบใหมิ&จากุ LR มิาด'วีย shallow and rapid breathing at 70/min, irregular, with nasal flaring and mild retraction
• suction เสมิหะขาวีข�&นมิ�จ!านวีนมิากุ O2 Sat=98%• No cyanosis, asphyxia, thick meconium, or
fever noted• Admitted at 39 minutes old (4:15 AM)
Family History
• No known heredofamilial diseases• No exposure to smoking in the family
Physical Examination
V/S• T=37.2°C• PR=137/min,
regular• RR=74/min• SpO2 94%• BP=63/39
mmHg
Anthropometry• BW=2,200
gms• Lt=46 cm• HC=33 cm• CC=28 cm
GA• Active• No
dysmorphic feature
• Dyspneic with nasal flaring
Physical Examination
Skin• No pallor, no
jaundice, no cyanosis, no plethora
• No purpura
HEENT• Fontanelles not
depressed or bulging
• No mass or swollen scalp
• No cleft lip/palate
• No ear or nasal secretion
Chest/ Lungs• Symmetrical, no
lesions, (+) mild retractions, no lags
• Tachypnea• Equal breath
sounds• No stridor, no
crepitation, no wheezes/rhonchi
Physical Examination
Heart• No visible
hyperactive precordium
• Normal rate, regular rhythm
• Normal S1 S2• No murmur• No distant heart
sounds• No thrills
Abdomen• Globular, no
distention, no lesions
• Normoactive bowel sounds
• Soft, no tenderness, no spleen or liver enlargement
Genitalia• Normal male
genitalia
Physical Examination
Anus• Patent
Extremities• Warm pink• No gross
deformities• No clubbing• No edema• No collapsing
pulses
Neuro• Alert• No stiff neck• Normal grasping
reflex• Babinski positive
Problem List
• PPROM of 4 hrs• Preterm (35 weeks)• Respiratory Distress soon after birth
– Dyspnea– Tachypnea (70/min)– Nasal flaring– Mild retraction
Differential Diagnoses(Respiratory Distress)
Pulmonary Conditions
• TTN (Wet lung syndrome)
• RDS/HMD• Congenital Pneumonia• Meconium aspiration
syndrome• Perinatal asphyxia
Extrapulmonary Conditions
• Sepsis• Pneumothorax• Hypoglycemia• Polycythemia• Cold stress• Hypothermia
Extra Notes (Hidden Slide): RD that can be ruled out initially
MAS: no history of mconium stained
Pneumothorax: no history of fetal distress, resuscitation, difficult
delivery, aspiration of meconium, blood, or mucus; in PE findings: (-) cyanosis, symmetrical chest wall on
expansion, equal breath sounds, liver not palpable, and no distant
heart sounds
Perinatal asphyxia: APGAR 9,10,10 with
no history of fetal distress, resuscitation, or meconium stained
Cardiac conditions (heart failure or PDA): no murmur, collapsing pulses, cyanosis, or
hepatomegaly
Cold stress or hypothermia: no history of low or
unstable temp recorded within 39 minutes of life
Pulmonary ConditionsDifferential diagnosis
PROS CONS Investigation
Transient Tachypnea of Newborn
• Preterm• C/S• RD soon after birth
- CXR
Respiratory Distress Syndrome / Hyaline Membrane Disease
• Preterm• RD soon after birth
• Active• No cyanosis• No edema
CXR
Congenital Pneumonia
• Preterm• PROM• RD soon after birth
• No maternal/NB fever• No records of predisposing factors: (no chorioamnionitis, no offensive liquor at birth)• PROM < 18 hours
CBCHemocultureCXR
Extrapulmonary ConditionsDifferential diagnosis
PROS CONS Investigation
Sepsis • RD• Preterm• PROM
• Active with APGAR 9,10,10
• PROM <18 hrs• no maternal/NB fever• Other SIRS criteria not
met
• CBC• H/C• UA• CRP
Hypoglycemia • RD• Preterm
• Active• No maternal DM
DTX
Congenital Anomalies
RD • No pertinent PE findings
CXR
Polycythemia / Anemia
RD • No plethora / pallor• Active
CBC
Laboratory Investigation9/5/57• CBC
– Corrected WBC=12,210uL; Neutrophils 43%, Lymphocytes 53%, Eosinophils 4%
– Hb=14.5 g/dL; Hct=43.4%– Platelet count = 398,000 uL
• CXR = no infiltrate, air bronchogram, haziness, mediastinal shift, cardiomegaly or anomalies
• DTX=81 mg%
11/5/57• CRP < 5.0 mg/L• H/C = No growth
After investigations, the ff may be ruled out:
CBC:•Congenital Pneumonia (confirmed again with CXR)•Sepsis (other 3 criteria of SIRS are not met: Temp, HR, WBC; confirmed again with CRP and H/C)•Polycythemia•Anemia
CXR:•RDS•Congenital Pneumonia (agreed with CBC)•Congenital Anomalies•MAS•Pneumothorax•Heart Failure
DTX:
•Hypoglycemia
CRP & H/C
•agreed with CBC for Sepsis
Transient Tachypnea of NewbornImpression:
Management Plan
One-day Orders• NPO (due to RD to
prevent aspiration)• Start IV fluid
– 10% D/W 500ml IV 5.9 cc/hr
• On O2 box 5LPM• Keep O2 sat ≥92%• Vitamin K 1mg IM• Supportive care
Continuous Orders• Antibiotics 5 days
– Ampicillin 220 mg IV q 12 hr– Gentamicin 8.5 mg IV OD– Couldn’t rule out Early Onset
Sepsis on admission, hence give Ampicillin (100 mkdose) + Gentamicin (4 mkdose)
• Routine newborn care, record V/S q 4 hours (SBP, Temp, RR, HR, SaO2), record BW OD, record Lt & HC once a week
Progress Notes
Thank You