Syllabus Template

BIOL 3220K Genetics (4 hours) Summer 2015Department of Biology

University of North Georgia - DahlonegaSection A (crn 3498)

Lecture: MTWR 0830-1040 Lab: MW 1105-1405Professor:Shane A. Webb, Ph.D.

shane.webb@ung.edu

408 Health & Natural Sciences Bldg.

ph: 706-867-2947

Office Hours:M,W 1405-1505, T,R 1040-1240 & by appt. fax: 867-2703

Course Description: A study of the principles of inheritance to include transmission, molecular, and population genetics. Topics include gene action, transfer systems and mapping, and cytological genetics. With laboratory.Prerequisites: BIOL 1107K (C or better), BIOL 1108K and CHEM 1211/1211L.Course Objectives: On completion of this course students should be able to:

i. Describe the fundamental concepts of transmission & molecular genetics.

ii. Use probability, statistics and other quantitative methods to solve problems in transmission genetics.

iii. Articulate how genetics relates to the biology, health & welfare of humans.

iv. Describe the major machinery and processes of DNA replication and gene expression.

v. Discuss recent technology that has impacted the field of genetics, and understand the ethical implications of these advances.

vi. Apply the scientific method to the collection, analysis & interpretation of genetic data.

This course aims to introduce you to the fundamental concepts of genetics while stressing critical thinking and problem solving skills. Memorization of facts and methods will be necessary, but not sufficient to master this course. It is hoped that you leave this class better prepared to think and work in a scientific manner. An understanding of the principles of inheritance will make you more critical of the ways society will choose to use the knowledge we are rapidly accumulating in this field.

Methods of Instruction: Course consists of four, 120-minute lectures and two, three-hour laboratories each week. Lectures will emphasize basic concepts in genetics. Questions and discussion are encouraged. Homework within Mastering Genetics will be given to stress important concepts and prepare you for quizzes and exams.During the course of this term you will be performing laboratory experiments using a variety of model organisms. The purpose of these experiments is to give you an opportunity to gain skills that you may use in future research/study, and to deepen your understanding of basic principles covered in the lecture. You will keep an 8.5 x 11 lab notebook that I will grade during exams (see Notebook specifications in lab manual).Evaluation Methods: Your final grade will be based on a 490 point total. You will be rewarded for your performance alone, not your performance relative to your peers. This is intended to encourage cooperative learning (e.g. comparing notes & studying). You are guaranteed the letter grade associated with the following intervals (rounded to the nearest % point): A ((90%), B (80-89%), C (70-79%), D (60-69%), F ((59%). You can evaluate your course performance with the file .Point allocation is as follows:

200 ptsTwo midterm exams (lecture & lab content; 100 pts each)

100 ptsCumulative final exam (lecture & lab content; ~half old/new material)

40 ptsDrosophila assessment (40pts; details TBA) 50 ptsLecture quizzes (five of 10 pts each; drop one; scaled to 50pts)

50 ptsMastering homework (posted within the site; scaled to 50 pts)

(If you earn >80% ( 50 pts; >70% ( 40 pts; > 60% ( 35 pts) 50 ptsLaboratory notebook (checked during all exams) & participation

0 ptsGCA bonus (10 pts) for top 50% of students (pre + post)

490 pts

General Expectations

Absence/attendance policy: Refer to the NG Student Handbook for attendance policies. Students that miss 10% of scheduled classes (lecture & lab combined) will be dropped from the course (W or WF) on the basis of excessive absences. Please note that for this summer, short-session course, 10% is three class meetings! Additionally, due to the nature of many of the labs they cannot be repeated at a later date. Failure to attend will therefore result in forfeiture of associated points. You are responsible for all assignments and announcements made in lecture, lab or disseminated online. "I didn't know" is not an acceptable excuse for failure to comply with course requirements.

Exams and quizzes MUST be taken at the scheduled time. If missed due to illness or family emergency, it must be documented in detail by a medical doctor. The availability, scheduling, and format of make-ups are at my discretion.Classroom participation policy: It is expected that students will participate actively in lecture and laboratory. This means, among other things, being respectful (of me, your peers, and the learning environment). If you take notes electronically, no Facebook, Twitter, YouTube, email, etc. Silence phones!

Required activities outside of class time: As we will be working with living organisms, some experiments require attention outside of scheduled laboratory sessions.Individual vs. collaborative work policy: You are encouraged to collaborate with your partner(s)/classmates while studying and in the discussion of lecture concepts, but NOT in the collection of research materials, analysis of data, production of graphs or writing of labs, reports, etc. I reserve the right to use any means necessary to detect cheating and/or plagiarism. Violating this policy will result in formal referral of the instance of cheating or plagiarism to the Academic Integrity Council, and may result in a failing grade in the course. Subsequent violations can result in expulsion from the university.Note: Students should go to theSupplemental Syllabus (http://ung.edu/academic-affairs/policies-and-guidelines/supplemental-syllabus.php) for information regarding Academic Exchange, Academic Integrity Policy, Academic Success Plan Program, Class Evaluations, Course Grades and Withdrawal Process, Disruptive Behavior Policy, Inclement Weather, Smoking Policy, and Students with Disabilities.Knowledge Base - Required text (you may use any of these three formats): Klug, W.S., et al. 2012. Concepts of Genetics, 10th edition. Pearson.

Hardcopy with Access Code (ISBN9780321732330)

Loose Leaf with Access Code (ISBN 9780321792174)

EText with Access Code (ISBN 9780321751010)Optional: You can purchase access to FlyLab ($7) at http://biologylab.awlonline.com/

Buy Now > Online Subscriptions > FlyLab (click on price)Supplementary materials: G: Academic Share > Biology > Webb > Genetics Supplementary materials: Other texts are on reserve in the library.

Hierarchical Learning Levels (bold levels stressed in this course):

Knowledge is the ability to recall or recognize information.

Comprehension is the ability to understand or use information within a limited context.

Application is the ability to use abstractions in particular situations.

Analysis is the ability to break information into its parts to clarify relationships.

Synthesis is the ability to create new concepts through examination of other information.

Evaluation is the ability to use standards and criteria to make judgments.

Mathematics integral to success in this course include:Algebraic manipulation and solving for variables, standard curves (linear and nonlinear), exponents and logarithms, X2 goodness of fit statistical test, descriptive statistics (mean, standard deviation and variance), probabilities (multiplication rule, addition rule, conditional, binomial expansion), combinatorial math, serial dilutions, molarity and concentration calculations (including composite solutions), and using MS Excel to plot graphs.

Note: You will be signing a document during Drop/Add that states you are fully aware of the contents of the syllabus. This means you need to read every word of this document. The statement: I (the undersigned) have read the Summer 2015 Genetics syllabus in its entirety and hereby verify that I understand its contents and am fully aware of my academic responsibilities in the course. I also understand what will be expected of me in terms of professional behavior.

Failure to sign & date this form will result in your removal from the course.Course Schedule(subject to change)

DayDateTopicChaptersLab (M & W)Quizzes

& ExamsAdditional

1wJun 24Introduction; Cell divisions & life cycles21: GCA; Intro Lab

2r25(contd)Drop/Add ends

3m29Mendelian genetics32: Drosophila assess.Quiz 1

4t30Mendelian extensions & sex linkage4, 7& Prob & X2

5wJul 1(contd)3: Biochem geneticsQuiz 2

6r2Genetic linkage & mapping5

7m6(contd)4: ComplementationEXAM 1Notebook due!

8t7Non-Mendelian genetics9W period ends

9w8Chromosomal variation85: Tetrad analysisQuiz 3

10r9(contd)

11m13D/RNA Structure; Replication10, 129: Restriction mappingQuiz 4

12t14Replication (contd)11

13w15Transcription136: DNA extraction

14r16Translation14EXAM 2Notebook due!

15m20Gene regulation16-176 & 7: Quant / PCR

16t21Mutation; Repair15

17w22Quantitative genetics2310: Fly assess.; GCAQuiz 5

18r23FINAL EXAM Thursday, July 23rd, 0830-1030Notebook due!

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