case presentation 2 ibtisam
TRANSCRIPT
What are u going to do???
53 years old Indian man presented to A&E at 11:30 am on 25/1/2010 with bilateral lower limbs pain and swelling…
History
53 yrs, Indian, not k/c/o any previous medical problem, was well until 2 weeks before presentation when he started to have on/off h/o LL pain treated in private clinic as MS pain?? and given analgesia, the pain was becoming worse untill 25/1/2010 when he present to Badr al Samawith sever bilateral lower limbs pain started early morning, associated with bilateral limb swelling, and he reffered to us as acute limb ischemia.
Cont.. History
No h/o truma
No chest pain or SOB
Other SR :unremarkable
He is working as trunk driver
Smokes 4ciggrates /day
Secondary Survey…
Head and Neck
Chest
CVS
P/A
Spine
CNS
Extremities: bilateral lower limb cyanosis and swelling with dilated veins, pulses are faint and both limb cold, no neurodefect
How he was managed?
Triage to Cubical area at 11:40am
Analgesia :morphine 10mg IV
Blood investigations sent
CT angiography LL (pt came back at 13:00)
Pt sent back to radiology department at 14:00 for
Ultrasound doppler
Seen by medical oncall: impression compartment syndrome plan to be started on anticoagulation and to be reffered to either vascular or general surgery
Cont,,,
At 14:50 pt started to have chest pain and SOB, shifted to rescues, arrested at 14:57, CPR started, (started on anticoagulation and thrombolysis)
After 15min regain pulse with low BP
Evaluated by: surgeon oncall advice IVC filter
Seen by cardiologist had bedside echo reported as sever RV hypokinesia with massive PE
Kept in A&E awaiting for bed until 17:00 when arrested again, CPR activated
Declared dead at 17:22
Definition:
It is a rare form of massive proximal venous thrombosis of the lower extremities associated with a high degree of morbidity and mortality, presenting with sudden severe lower extremity pain with edema and cyanosis.
Work up
Contrast venography : the gold standard, but it has technical difficulties
Duplex ultrasonography
Magnetic resonance venography (MRV) is an evolving modality of diagnostic imaging. Its principal advantage is its ability to easily reveal the proximal and distal extent of thrombus with a single study.
Treatment
Medical Therapy:
=steep limb elevation, anticoagulation with intravenous administration of heparin, and fluid resuscitation, should be the initial course of therapy
=bolus of 150 u/kg, followed by a continuous infusion of 40 u/kg/h.
Surgical Therapy:
=Surgical thrombectomy
=IVC filter application
Thrombolysis :
Systemic thrombolysis has also been used. Many authors have strongly recommended the insertion of a vena caval filter prior to initiation of thrombolytic therapy.
catheter-directed thrombolysis directly into the vein with high doses of urokinase or tissue plasminogen activator (t-PA).
intra-arterial low-dose thrombolysis via the common femoral artery
Complications
Pulmonary embolism is common, and prophylactic placement of an inferior vena cava filter is recommended in most cases.
Venous gangrene, venous congestion with massive fluid sequestration leading to circulatory collapse, and shock causing death
Amputation and death are common.
Post-phlebitic syndrome and re-thrombosis may be as high as 94% among survivors.
UP to DATE
Most patients, when diagnosed early, respond
to bed rest, extremity elevation, fluid resuscitation,
and systemic anticoagulation. If there is no response to
these measures within 12 hours, thrombolytic therapy
with catheter-based delivery should be instituted. If there
is a contraindication to thrombolytic therapy, venous
thromboectomy should be undertaken. For patients whose
condition is far advanced at presentation, thrombolytic
therapy or venous thromboectomy should be considered as
part of the initial therapeutic plan.
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Do not be missed lead by referral diagnose
Common is common but still Be highly suspicious and keep the rare condition in ur mind
As treating clinician follow ur index of suspicion and do not get influence by others
Even if A&E is busy always follow up ur patient because time is fatal