久留米大学病院...
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久留米大学病院
久留米大学病院病理診断科・病理部のあゆみ
2001−2015Department of Diagnostic Pathology
Kurume University Hospital
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5.�Kaida�H,�Ishibashi�M,�Yuzuriha�M,�Kurata�S,�Arikawa�S,�Kawahara�A,�Uozumi�J,�Uchida�M,�Kobayashi�M,�Hirose�Y,�FUjita�H,�Kage�M,� �Hayabuchi�N.�Glucose�transporter�expression�of�an�esophageal�gastrointestinal�tumor�detected�by�F�18�FDG�PET/CT.�Clin�Nucl�Med.�2010;�35:�505�509.���6.�Miura�S,�Azuma�K,�Yamada�K,�Takamori�S,�Kawahara�A,�Noda�K,� �Ayabe�M,�Kage�M,�Aizawa�H,�Tanikawa�T.�Combined�treatment�with�prednisolone�and�tacrikunys�fir�myasthenia�gravis�with�invasive�thymoma.�Acta�Neurol�Belg.�2010;�110:�107�109.���7.�Yamamoto�C,�Basaki�Y,�Kawahara�A,�Nakashima�K,�Kage�M,�Izumi�H,�Kohno�K,�Uramoto�H,�Yasumoto�K,�Kuwano�M,�Ono�M.� �Loss�of�PTEN�expression�by�blocking�nuclear�translocation�of�EGR1�in�gefitinib�resistant�lung�cancer�cells�harboring�epidermal�growth�factor�receptor�activating�mutations.� �Cancer�Res.�2010;�70:�8715�25.���8.�Kaji�R,�Okabe�Y,�Ishida�Y,�Takedatsu�H,�Kawahara�A,�Aino�H,�Morimitsu�Y,�Maekawa�R,�Toyonaga�A,�Tsuruta�O,�Sata�M.� �Autoimmune�pancreatitis�presenting�with�IgG4�positive�multiple�gastric�polyps.� �Gastrointest�Endosc.�2010;�71:�420�2.���9.�Fukushima�N,�Kuromatsu�R,�Akiba�J,�Ando�E,�Takata�A,�Sumie�S,� �Nakano�M,�Nakamura�T,�Kawahara�A,�Torimura�T,�Nakashima�O,�Okuda�K,�Yano�H,�Kage�M,�Kojiro�M,�Sata�S.� �Characteristic�expression�pattern�of�oxidative�stress�in�livers�with�cryptogenic�hepatocellular�carcinoma.� �Experimental�and�Therapeutic�Medicine�2010;�1:�809�816.���10.�Kimura�A,�Kage�M,�Nagata�I,�Mushiake�S,�Ohura�T,�Tazawa�Y,�Maisawa�S,�Tomomasa�T,�Abukawa�D,�Okano�Y,�Sumazaki�R,�Takayanagi�M,� �Tamamori�A,�Yorifuji�T,�Yamato�Y,�Maeda�K,�Matsushita�M,�Matsuishi�T,�Tanikawa�K,�Kobayashi�K,�Saheki�T.�Histological�findings�in�the�livers�of�patients�with�neonatal�intrahepatic�cholestasis�caused�by�citrin�deficiency.�Hepatol�Res.�2010;�40:�295�303.���11.�Tajiri�T,�Yoshida�H,�Obara�K,�Onji�M,�Kage�M,�Kitano�S,�Kokudo�N,�Kokubu�S,�Sakaida�I,�Sata�M,�Tajiri�H,�Tsukada�K,�Nonami�T,�Hashizume�M,�Hirota�S,�Murashima�N,�Moriyasu�F,�Saigenji�K,�Makuuchi�H,�Oho�K,� �Yoshida�T,�Suzuki�H,�Hasumi�A,�Okita�K,�Futagawa�S,�Idezuki�Y.�General�rules�for�recording�endoscopic�findings�of�esophagogastric�varices�(2nd�edition).�Dig�Endosc.�2010;�22:�1�9.���12.�Kobayashi�H,�Tanaka�Y,�Asagiri�K,�Asakawa�T,�Tanikawa�K,�Kage�M,� �Yagi�M.�The�antioxidant�effect�of�green�tea�catechin�ameliorates�experimental�liver�injury.�Phytomedicine.�2010;�17:�197�202.� ��13.�Shiota�M,�Saitou�K,�Mizumoto�H,�Matsusaka�M,�Agata�N,�Nakayama�M,�Kage�M,�Tatsumi�S,�Okamoto�A,�Yamaguchi�S,�Ohta�M,�Hata�D.�Rapid�Detoxification�of�Cereulide�in�Bacillus�cereus�Food�Poisoning.�Pediatrics.�2010;�125:�e951�955.���14.�Karino�Y,�Toyota�J,�Kumada�H,�Katano�Y,�Izumi�N,�Kobashi�H,�Sata�M,�Moriyama�M,�Imazeki�F,�Kage�M,�Ishikawa�H,�Masaki�N,�Seriu�T,�Omata�M.�Efficacy�and�resistance�of�entecavir�following�3�years�of�treatment�of�Japanese�patients�with�lamivudine�refractory�chronic�hepatitis�B.�Hepatol�Int.�2010;�4:�414�422.���15.�Yamaguchi�R,�Tanaka�M,�Yamaguchi�M,�Fukushima�T,�Kaneko�Y,� �Otsuka�H,�Isobe�S,�Terasaki�H,�Nakashima�O,�Kage�M,�Yano�H.�Pleomorphic�carcinoma�of�the�breast�in�a�17�year�old�woman.�Med�Mol�Morphol.�2010;�43:�43�47.��16.�Nakanuma�Y,�Zen�Y,�Harada�K,�Sasaki�M,�Nonomura�A,�Uehara�T,�Sano�K,�Kondo�F,�Fukusato�T,�Tsuneyama�K,�Ito�M,�Wakasa�K,�Nomoto�M,�Minato�H,�Haga�H,�Kage�M,�Yano�H,�Haratake�J,�Aishima�S,�Masuda�T,�Aoyama�H,�Miyakawa�Hayashino�A,�Matsumoto�T,�Sanefuji�H,�Ojima�H,�Chen�TC,�Yu�E,�Kim�JH,�Park�YN,�Tsui�W.� �Application�of�a�new�histological�staging�and�grading�system�for�primary�biliary�cirrhosis�to�liver�biopsy�specimens:�interobserver�agreement.�Pathol�Int.�2010;�60:�167�174.��
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7.�Naito�Y,�Okabe�Y,�Nagayama�M,�Nishinakagawa�T,�Taira�T,�Kawahara�A,�Hattori�S,�Machida�K,�Ishida�Y,�Kaji�R,�Mikagi�K,�Kinoshita�H,�Yasumoto�M,�Akiba�J,�Kage�M,�Nakashima�M,�Ohshima�K,�Yano�H.�Accuracy�of�differential�diagnosis�for�pancreatic�cancer�is�improved�in�the�combination�of�RCAS1�and�CEA�measurements�and�cytology�in�pancreatic�juice.�Med�Mol�Morphol.�2011;�44:�86�92.� ���8.�Shiratsuchi�I,�Akagi�Y,�Kawahara�A,�Kinugasa�T,�Romeo�K,�Yoshida�T,�Ryu�Y,�Gotanda�Y,�Kage�M,�Shirouzu�K.�Expression�of�IGF�1�and�IGF�1R�and�their�relation�to�clinicopathological�factors�in�colorectal�cancer.�Anticancer�Res.�2011;�31:�2541�2545.���9.�Kaida�H,�Hiromatsu�Y,�Kurata�S,�Kawahara�A,�Hattori�S,�Taira�T,� �Kobayashi�M,�Uchida�M,�Yamada�K,�Mihashi�H,�Umeno�H,�Kage�M,�Nakashima�T,�Hayabuchi�N,�Ishibashi�M.�Relationship�between�clinicopathological�factors�and�fluorine�18�fluorodeoxyglucose�uptake�in�patients�with�papillary�thyroid�cancer.�Nucl�Med�Commun.�2011;�32:�690�698.���10.�Hirose�Y,�Kaida�H,�Ishibashi�M,�Kawahara�A,�Kobayashi�M,�Hayabuchi�N.� �Glucose�transporter�expression�of�intraductal�papilloma�of�the�breast�detected�by�fluorodeoxyglucose�positron�emission�tomography.� �Jpn�J�Radiol.�2011;�29:�217�21.���11.�Akiba�J,�Harada�H,�Kawahara�A,�Arakawa�F,�Mihashi�H,�Mihashi�R,�Ohshima�K,�Yano�H.� �Histiocytic�sarcoma�of�the�parotid�gland�region.� �Pathol�Int.�2011;�61:�373�6.� ���12.�Yoshida�T,�Kinugasa�T,�Akagi�Y,�Kawahara�A,�Romeo�K,�,�Shiratsuchi�I,�Ryu�Y,�Gotanda�Y,�Shirouzu�K.� �Decreased�Expression�of�Claudin�1�in�Rectal�Cancer:�A�Factor�for�Recurrence�and�Poor�Prognosis.� �Anticancer�Res.�2011;�31:�2517�25.� ��13.�Fotovati�A,�Abu�Ali�S,�Kage�M,�Shirouzu�K,�Yamana�H,�Kuwano�M.�N�myc�downstream�regulated�gene�1(ndrg1)�a�differentiation�marker�of�human�breast�cancer.�Pathol�Oncol�Res.2011;�17:�525�533.� ���14.�Fujimoto�K,�Tonan�T,�Azuma�S,�Kage�M,�Nakashima�O,�Johkoh�T,�Hayabuchi�N,�Okuda�K,�Kawaguchi�T,�Sata�M,�Qayyum�A.�Evaluation�of�the�mean�and�entropy�of�apparent�diffusion�coefficient�values�in�chronic�hepatitis�c:�correlation�with�pathologic�fibrosis�stage�and�inflammatory�activity�grade.�Radiology.�2011;�258:�739�748.� ���15.�Mizuochi�T,�Kimura�A,�Nishiura�H,�Inomata�Y,�Okajima�H,�Sugie�H,�Mitsubuchi�H,�Yagi�M,�Kage�M.�Liver�biopsy�is�an�important�procedure�in�the�diagnosis�of�glycogen�storage�disease�typeIV.�Pediatr�Int.�2011;�53:�129�130.� ���16.�Nomura�Y,�Naito�Y,�Eriguchi�N,�Kume�T,�Itai�N,�Sonoda�H,�Hayashida�S,�Naito�S,�Naito�H,�Yasumoto�M,�Akiba�J,�Kinoshita�H,�Yano�H,�Kage�M.�A�case�of�IgG4�related�sclerosing�mesenteritis.�Pathol�Res�Pract.�2011;�207:�518�521.� ���17.�Kawaguchi�T,�Kaji�R,�Horiuchi�H,�Shirono�T,�Ishida�Y,�Okabe�Y,�Itou�M,�Mitsuyama�K,�Akiba�J,�Nakashima�O,�Yano�H,�Kage�M,�Harada�M,� �Sakisaka�S,�Sata�M.�Development�of�intrahepatic�cholangiocarcinoma�after�a�14�year�follow�up�of�a�patient�with�primary�sclerosing�cholangitis�and�ulcerative�colitis.�Hepatol�Res.�2011;�41:�1253�1259.���18.�Takenaka�M,�Toh�U,�Otsuka�H,�Takahashi�H,�Iwakuma�N,�Nakagawa�S,�Fujii�T,�Yamaguchi�R,�Yano�H,�Shirouzu�K,�Kage�M.�Giant�malignant�phyllodes�tumor:�a�case�report.�Kurume�Med�J.�2011;�58:�67�72.���
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13.�Yamaguchi�R,�Tanaka�M,�Yokoyama�T,�Nonaka�Y,�Mizushima�Y,� �Kawahara�A,�Yoshida�T,�Ito�T,�Yamaguchi�M,�Kage�M,�Yano�H.�Cytological�features�of�myxomatous�fibroadenoma�of�the�breast.�Diagn�Cytopathol.�2012;�40:�316�320.���14.�Tonan�T,�Fujimoto�K,�Qayyum�A,�Morita�Y,�Nakashima�O,�Ono�N,�Kawahara�A,�Kage�M,�Hayabuchi�N,�Ueno�T.� �CD14�expression�and�Kupffer�cell�dysfunction�in�nonalcoholic�steatohepatitis:�SPIO�MRI�and�pathologic�correlation.�J�Gastroenterol�Hepatol.�2012;�27:�789�796.���15.�Akagi�Y,�Kinugasa�T,�Mizobe�T,�Kawahara�A,�Kage�M,�Shirouzu�K.�Expression�of�dihydropyrimidine�dehydrogenase,�orotate�phosphoribosyl�transferase�and�thymidylate�synthase�in�patients�with�primary�colorectal�cancer,�and�associations�with�site�of�first�metastasis.�Anticancer�research.�2012;�32:�2277�2282.��16.�Kinugasa�T,�Akagi�Y,�Ochi�T,�Tanaka�N,�Kawahara�A,�Ishibashi�Y,� �Gotanda�Y,�Yamaguchi�K,�Shiratuchi�I,�Oka�Y,�Kage�M,�Shirouzu�K.�Increased�claudin�1�protein�expression�in�hepatic�metastatic�lesions�of�colorectal�cancer.�Anticancer�Res.�2012;�32:�2309�2314.���17.�Ohchi�T,�Akagi�Y,�Kinugasa�T,�Kakuma�T,�Kawahara�A,�Sasatomi�T,�Gotanda�Y,�Yamaguchi�K,�Tanaka�N,�Ishibashi�Y,�Miyamoto�S,�Kage�M,�Shirouzu�K.�Amphiregulin�is�a�prognostic�factor�in�colorectal�cancer.�Anticancer�Res.�2012;�32:�2315�21.���18.�Tabara�K,�Kanda�R,�Sonoda�K,�Kubo�T,�Murakami�Y,�Kawahara�A,� �Azuma�K,�Abe�H,�Kage�M,�Yoshinaga�A,�Tahira�T,�Hayashi�K,�Arao�T,�Nishio�K,�Rosell�R,�Kuwano�M,�Ono�M.�Loss�of�activating�EGFR�mutant�gene�contributes�to�acquired�resistance�to�EGFR�tyrosine�kinase�inhibitors�in�lung�cancer�cells.�PLoS�One.�2012;�7:�e41017.� ���19.�Ureshino�H,�Murakami�Y,�Watari�K,�Izumi�H,�Kawahara�A,�Kage�M,� �Arao�T,�Nishio�K,�Yanagihara�K,�Kinoshita�H,�Kuwano�M,�Ono�M.�N�myc�downstream�regulated�gene�1�(NDRG1)�promotes�metastasis�of�human�scirrhous�gastric�cancer�cells�through�epithelial�mesenchymal�transition.�PLoS�One.�2012;�7:�e41312.���20.�Naito�Y,�Kusano�H,�Nakashima�O,�Sadashima�E,�Hattori�S,�Taira�T,�Kawahara�A,�Okabe�Y,�Shimamatsu�K,�Taguchi�J,�Momosaki�S,�Irie�K,�Yamaguchi�R,�Yokomizo�H,�Nagamine�M,�Fukuda�S,�Sugiyama�S,�Nishida�N,�Higaki�K,�Yoshitomi�M,�Yasunaga�M,�Okuda�K,�Kinoshita�H,�Nakayama�M,�Yasumoto�M,�Akiba�J,�Kage�M,�Yano�H.�Intraductal�neoplasm�of�the�intrahepatic�bile�duct:�clinicopathological�study�of�24�cases.�World�J�Gastroenterol.�2012;�18:�3673�3680.���21.�Seki�N,�Toh�U,�Kawaguchi�K,�Ninomiya�M,�Koketsu�M,�Watanabe�K,� �Aoki�M,�Fujii�T,�Nakamura�A,�Akagi�Y,�Kusukawa�J,�Kage�M,�Shirouzu�K,�Yamana�H.�Tricin�inhibits�proliferation�of�human�hepatic�stellate�cells�in�vitro�by�blocking�tyrosine�phosphorylation�of�PDGF�receptor�and�its�signaling�pathways.�J�Cell�Biochem.�2012;�113:�2346�2355.���22.�Yamaguchi�R,�Tanaka�M,�Kondo�K,�Yokoyama�T,�Maeda�I,�Tsuchiya�S,�Yamaguchi�M,�Takahashi�R,�Ogata�Y,�Abe�H,�Akiba�J,�Nakashima�O,�Kage�M,�Yano�H.�Immunohistochemical�study�of�metaplastic�carcinoma�and�central�acellular�carcinoma�of�the�breast:�central�acellular�carcinoma�is�related�to�metaplastic�carcinoma.�Med�Mol�Morphol.�2012;�45:�14�21.���23.�Mizuochi�T,�Kimura�A,�Tanaka�A,�Muto�A,�Nittono�H,�Seki�Y,�Takahashi�T,�Kurosawa�T,�Kage�M,�Takikawa�H,�Matsuishi�T.�Characterization�of�urinary�bile�acids�in�a�pediatric�BRIC�1�patient:�Effect�of�rifampicin�treatment.�Clin�Chim�Acta.�2012;�413:�1301�1304.�
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1.�Kawahara�A,�Harada�H,�Abe�H,�Yamaguchi�T,�Taira�T,�Mihashi�H,�Naito�Y,�Akiba�J,�Kage�M.� �Fine�needle�aspiration�cytology�of�metastatic�polymorphous�low�grade�adenocarcinoma�of�the�palate�in�cervical�lymph�node.� �Cytopathology.�2013;�24:�63�5.���2.�Akiba�J,�Harada�H,�Kawahara�A,�Todoroki�K,�Nagata�S,�Yano�H.� �A�case�of�metastasizing�pleomorphic�adenoma�in�the�maxillary�bone�appearing�twenty�years�after�initial�resection�of�pleomorphic�adenoma�of�the�hard�palate.� �Pathol�Int.�2013;�63:�463�8.���� �
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3.�Gotanda�Y,�Akagi�Y,�Kawahara�A,�Kinugasa�T,�Yoshida�T,�Ryu�Y,� �Shiratsuchi�I,�Kage�M,�Shirouzu�K.� �Expression�of�monocarboxylate�transporter�(MCT)�4�in�colorectal�cancer�and�its�role:�MCT4�contributes�to�the�growth�of�colorectal�cancer�with�vascular�endothelial�growth�factor.�Anticancer�Res.�2013;�33:�2941�2947.���4.�Murakami�Y,�Watari�K,�Shibata�T,�Uba�M,�Ureshino�H,�Kawahara�A,� �Abe�H,�Izumi�H,�Mukaida�N,�Kuwano�M,�Ono�M.� �N�myc�downstream�regulated�gene�1�promotes�tumor�inflammatory�angiogenesis�through�JNK�activation�and�autocrine�loop�of�interleukin�1��by�human�gastric�cancer�cells.�J�Biol�Chem.�2013;�30;�288:�25025�37.���5.�Kanda�R,�Kawahara�A,�Watari�K,�Murakami�Y,�Sonoda�K,�Maeda�M,� �Fujita�H,�Kage�M,�Uramoto�H,�Costa�C,�Kuwano�M,�Ono�M.�Erlotinib�resistance�in�lung�cancer�cells�mediated�by�integrin��1/Src/Akt�driven�bypass�signaling.�Cancer�Res.�2013;�73:�6243�6253.���6.�Shibata�T,�Kan�H,�Murakami�Y,�Ureshino�H,�Watari�K,�Kawahara�A,� �Kage�M,�Hattori�S,�Ono�M,�Kuwano�M.�Y�box�binding�protein�1�contributes�to�both�HER2/ErbB2�expression�and�lapatinib�sensitivity�in�human�gastric�cancer�cells.�Mol�Cancer�Ther.�2013;�12:�737�746.���7.�Takenaka�M,�Seki�N,�Toh�U,�Hattori�S,�Kawahara�A,�Yamaguchi�T,�Koura�K,�Takahashi�R,�Otsuka�H,�Takahashi�H,�Iwakuma�N,�Nakagawa�S,�Fujii�T,�Sasada�T,�Yamaguchi�R,�Yano�H,�Shirouzu�K,�Kage�M.� �FOXP3�expression�in�tumor�cells�and�tumor�infiltrating�lymphocytes�is�associated�with�breast�cancer�prognosis.� �Mol�Clin�Oncol.�2013;�1:�625�632.� ���8.�Takahashi�R,�Ishibashi�Y,�Hiraoka�K,�Matsueda�S,�Kawano�K,�Kawahara�A,�Kage�M,�Ohshima�K,�Yamanaka�R,�Shichijo�S,�Shirouzu�K,�Itoh�K,�Sasada�T.�Phase�II�study�of�personalized�peptide�vaccination�for�refractory�bone�and�soft�tissue�sarcoma�patients.�Cancer�Sci.�2013;�104:�1285�1294.���9.�Takahashi�R,�Toh�U,�Iwakuma�N,�Mishima�M,�Fujii�T,�Takenaka�M,� �Koura�K,�Seki�N,�Kawahara�A,�Kage�M,�Ogo�E,�Shirouzu�K.� �Treatment�outcome�in�patients�with�stage�III�breast�cancer�treated�with�neoadjuvant�chemotherapy.� �Exp�Ther�Med.�2013;�6:�1089�1095.� �� �10.�Isobe�T,�Aoyagi�K,�Koufuji�K,�Shirouzu�K,�Kawahara�A,�Taira�T,�Kage�M.�Clinicopathological�significance�of�hypoxia�inducible�factor�1�alpha�(HIF�1�)�expression�in�gastric�cancer.�Int�J�Clin�Oncol.�2013;�18:�293�304.���11.�Kaida�H,�Toh�U,�Hayakawa�M,�Hattori�S,�Fujii�T,�Kurata�S,�Kawahara�A,�Hirose�Y,�Kage�M,�Ishibashi�M.�The�relationship�between�18F�FDG�metabolic�volumetric�parameters�and�clinicopathological�factors�of�breast�cancer.�Nucl�Med�Commun.�2013;�34:�562�570.���12.�Yamashita�F,�Azuma�K,�Yoshida�T,�Yamada�K,�Kawahara�A,�Hattori�S,�Takeoka�H,�Zaizen�Y,�Kawayama�T,�Kage�M,�Hoshino�T.�Prognostic�value�of�EGFR�mutation�and�ERCC1�in�patients�with�non�small�cell�lung�cancer�undergoing�platinum�based�chemotherapy.�PLoS�ONE.�2013;�8:�e71356.���13.�Hisaka�T,�Horiuchi�H,�Uchida�S,�Ishikawa�H,�Kawahara�R,�Kawashima�Y,�Akashi�M,�Mikagi�K,�Ishida�Y,�Okabe�Y,�Nakayama�M,�Naito�Y,�Yano�H,� �Taira�T,�Kawahara�A,�Kage�M,�Kinoshita�H,�Shirozu�K.�Potential�usefulness�of�mucin�immunohistochemical�staining�of�preoperative�pancreatic�biopsy�or�juice�cytology�specimens�in�the�determination�of�treatment�strategies�for�intraductal�papillary�mucinous�neoplasm.�Oncol�Rep.�2013;�30:�2035�2041.���14.�Sakata�M,�Kawahara�A,�Kawaguchi�T,�Akiba�J,�Taira�T,�Taniguchi�E,� �Abe�M,�Koga�H,�Kage�M,�Sata�M.� �Decreased�expression�of�insulin�and�increased�expression�of�pancreatic�transcription�factor�PDX�1�in�islets�in�patients�with�liver�cirrhosis:�a�comparative�investigation�using�human�autopsy�specimens.� �J�Gastroenterol.�2013;�48:�277�285.���
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1.�Kawahara�A,�Taira�T,�Abe�H,�Watari�K,�Murakami�Y,�Fukumitsu�C,� �Takase�Y,�Yamaguchi�T,�Azuma�K,�Akiba�J,�Ono�M,�Kage�M.�Fixation�effect�of�SurePath�preservative�fluids�using�epidermal�growth�factor�receptor�mutation�specific�antibodies�for�immunocytochemistry.�Cancer�Cytopathol.�2014;�122:�145�52.���2.�Kawahara�A,�Akiba�J,�Abe�H,�Yamaguchi�T,�Taira�T,�Azuma�K,�Kage�M.�EML4�ALK�positive�lung�adenocarcinoma�with�signet�ring�cells.�Diagn�Cytopathol.�2014;�42:�460�463.�
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病理診断科・病理部のあゆみ 2015久留米大学病院
発行日:平成28年3月18日発行者:鹿毛 政義編集者:河原 明彦 安倍 秀幸 久留米大学病院 病理診断科・病理部 福岡県久留米市旭町67 TEL /FAX 0942-31-7651 http://pathology.kurume-univ.jp/