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Contents

3 Programme : Wednesday 8th April 6 Programme : Thursday 9th April 7 Posters & Exhibitors Plan 10 Opening Address 11 Plenaries 14 Biological Engineering 15 Education, Outreach & Training, EPSRC 18 Food & Water Security 19 Increased Manufacturing Value 21 Conference Dinner & City Centre Map 22 Materials Innovation 23 Meeting the Sustainable Energy Demand

Professor Geoff Maitland, Imperial College, President of IChemE On behalf of IChemE, welcome to this year’s ChemEngDayUK. We are delighted to continue to support this event, which has become a regular feature of the academic year. It is a great opportunity to find out about the great breadth of Chemical Engineering research being carried out by PhD students across the UK and for you all to meet colleagues from different technical areas and universities. The connections you establish could lead to new ideas and collaborations and some may stay with you for life. Many

thanks to Phil Wright and his team for hosting us and I look forward to meeting as many of you as possible around your posters. I hope you enjoy the technical sessions and social events and return home convinced more than ever that Chemical Engineering matters!

Geoff Maitland

Biological Engineering Education, Outreach & Training Food & Water Security Increased Manufacturing Value Materials Innovation Meeting the Sustainable Energy Demand Conference Team Exhibitor

Professor Phillip Wright, Head of Chemical and Biological Engineering, The University of Sheffield We are delighted to host this year’s ChemEngDayUK in Sheffield. Our conference dinner at the Cutlers’ Hall showcases the chemical engineering heritage of Sheffield as the ‘Steel City’ that led to the development of crucible and stainless streel manufacture throughout the world. We will provide colour coded lanyards with the name badges to help you identify colleagues with similar chemical engineering interests. I hope you enjoy

the opportunity to share your research knowledge and experiences through the themed seminar programme, research posters and with our valued event sponsors who you will find in the ballroom, alongside the research posters.

Phil Wright

Lanyard Theme

Welcome

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Wednesday 8th April 2015

09:00 - 10:30 Registration, Refreshments in the Ballroom

10:30 - 12:30 Memorial Hall : Opening Address Professor Mike Hounslow, PVC Engineering, University of Sheffield, Professor Geoff Maitland, Imperial College, President of IChemE Kedar Pandya, Head of Engineering Capability, EPSRC Sean McDonagh, Siemens UK

Memorial Hall : Plenary 1 Jeroen van der Veer, Former CEO, Shell “Some chemicals for your leadership’’

Memorial Hall : Plenary 2 Professor Ray Allen, Chemical & Biological Engineering, University of Sheffield “A History of the Future of Chemical Engineering”

12:30 - 13:30 Ballroom : Lunch

13:30 - 15:00 Memorial Hall : Manufacturing Value Chaired by Dr Mark Ogden, Chemical & Biological Engineering, University of Sheffield Dr. Teodora Retegan, Chemistry and Chemical Engineering, Chalmers University of Technology “Process valorisation through metal recovery from waste streams.” Dr Chris Tighe, Chemical Engineering, Imperial College London “High Pressure Industrial Systems, the challenge of chemistry, scale-up and engineering materials.” Professor David York, Institute of Particle Science and Engineering, University of Leeds “Conversion of commodity micro capsules into high value components for consumer products.”

North Seminar Room : Food & Water Security Chaired by Professor Catherine Biggs, Chemical & Biological Engineering, University of Sheffield Professor David Butler, Professor of Water Engineering, University of Exeter “The Water-Food-Energy Nexus “ John McGagh, Former Head of Technology and Innovation at Rio Tinto, Visiting Professor, SMI Centre for Water in the Minerals Industry “Water and mining: some challenges, progress and research needs.” Dr Constantijn Sanders, Group leader Powder Science & Encapsulation, Nestlé “Past, present and future examples from the dairy industry”

South Seminar Room : Materials Innovation Chaired by Dr Jonathan Howse, Chemical & Biological Engineering, University of Sheffield Dr Mark Haw, Chemical and Process Engineering, University of Strathclyde “Nanopropulsion by biocatalytic self-assembly: towards functional materials for nanoengineering“ Dr. Valeska Ting, Chemical Engineering, University of Bath “Nanoporous materials for applications in sustainable technologies” Dr Justin Tian, School of Pharmacy, Queen’s University “The introduction of thermodynamics in pharmaceutical formulation design and manufacturing”

15:00 - 15:30 Ballroom : Refreshments

15:30 - 16:30 Ballroom : Poster Session 1 : Even number posters supervised.

16:30 - 18:00 Memorial Hall : EPSRC Support for People: Leadership & Fellowships Kedar Pandya, Luke Davis & Ruqaiyah Patel, EPSRC Engineering Capability Theme

Archers Bar : Informal Advanced Careers Networking

18:00 Close of the days events at City Hall

19:30 - 00:00 Conference Dinner : Cutlers Hall

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Thursday 9th April 2015

08:30 - 09:00 Ballroom : refreshments

09:00 - 10:30 Memorial Hall : Meeting the Sustainable Energy Demand Chaired by Professor Peter Styring, Chemical & Biological Engineering, University of Sheffield John Bøgild Hansen, Senior Scientist, Haldor Topsøe “Chemical Engineering aspects of sustainable fuel production” Professor Paul Williams, Energy Research Institute, School of Chemical and Process Engineering, University of Leeds “Energy & Fuels from Wastes“

North Seminar Room : Education, Outreach & Training Chaired by Dr Martin Pitt, Chemical & Biological Engineering, University of Sheffield Dr Jarka Glassey, School of Chemical Engineering & Advanced Materials, Newcastle University “Engaging chemical engineers from day one” Professor Eva Sorensen, Chemical Engineering, University College London “Experiences of problem-based learning at UCL” Folashade Akinmolayan, Chemical Engineering, University College London “Widening participation initiatives” Dr Mark Haw, Chemical and Process Engineering, University of Strathclyde “Outreach to primary school level”

South Seminar Room : Biological Engineering Chaired by Dr Mark Dickman, Chemical & Biological Engineering, University of Sheffield Professor Nick Turner, School of Chemistry, University of Manchester “Design and Evolution of Biocatalysts for Organic Synthesis” Professor Kenneth F. Reardon, Professor and Jud and Pat Harper Chair of Chemical and Biological Engineering, Colorado State University “Addressing the challenges of large-scale phototrophic cultivations” Dr Steve Pearson, Head of Business & Strategy, Centre for Process Innovation “Innovation; process development & scale-up in IB”

10:30 - 11:00 Ballroom : Refreshments

11:00 - 12:00 Ballroom : Poster Session 2 : Odd number posters supervised.

Memorial Hall : Meeting the Sustainable Energy Demand Dr John Newton, ITM Power “Hydrogen: A vector for Renewable Energy Storage” Professor Peter Styring, University of Sheffield “Carbon dioxide utilisation for future energy storage”

North Seminar Room : : Manufacturing Value Professor Julian Morris, University of Newcastle “Smart Process Performance Monitoring “

12:00 - 13:00 Ballroom : Lunch

13:00 - 13:30 Closing ceremony, Theme Poster Awards & IChemE Photo Caption Winner Presented by Professor Mike Hounslow, PVC Engineering, University of Sheffield

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Ballroom Posters & Exhibition Area

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North Seminar Room Entrance

North Seminar Room Exit

Biological Engineering posters Meeting the sustainable energy demand posters

Materials innovation posters 13-33 Increased Manufacturing Value posters Food & Water Security posters

Materials innovation posters 1-12

Archers Bar area

South Seminar Room Exit

South Seminar Room Entrance

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Professor Geoff Maitland, Professor of Energy Engineering, Imperial College, President of IChemE After a period as an ICI Research Fellow at Bristol University, Geoff was appointed to a lectureship in Chemical Engineering at Imperial College in 1974. In 1986 Geoff moved to the oil and gas industry with Schlumberger, before rejoining Imperial College in 2005 as Professor of Energy Engineering. He is the founding Director of the Qatar Carbonates and Carbon Storage Research Centre. Geoff is a Fellow of the Institution of Chemical Engineers, the Royal Society of Chemistry, the Energy Institute

and the Royal Academy of Engineering. He was awarded the Hutchison Medal by the Institution of Chemical Engineers in 1998 and served as President of the British Society of Rheology. He was awarded the IChemE Chemical Engineering Envoy Award for 2010. In 2011 he chaired the independent review of the UK Offshore Oil and Gas Regulatory Regime (‘The Maitland Report’) and in 2012 received the Rideal Lecture Award from the Royal Society of Chemistry.

Professor Mike Hounslow, Pro-Vice-Chancellor of the Faculty of Engineering, The University of Sheffield Mike is responsible for the operation of all seven Engineering departments comprising more than 800 staff and 3000 students. Mike is a chemical engineer with BE and PhD degrees from the University of Adelaide in South Australia. He is a Chartered Engineer, a Fellow of the Institution of Chemical Engineers and a Fellow of the Royal Academy of Engineering. After completing the first of his degrees he worked for ICI

Australia for four years in a variety of technical and management roles before taking up a lectureship at Adelaide and commencing his PhD.In 1990 he moved to the University of Cambridge to take up a lectureship becoming a Fellow and then Dean of Selwyn College. In 1998 he moved to Sheffield and became Professor of Chemical Engineering. In 2000 he became Head of Department and in 2008 PVC.

Kedar Pandya, Head of Engineering capability theme, EPSRC Kedar's role is to stimulate and support ambitious engineering research for the long-term benefit of the UK. Key to success is supporting visionary leadership across traditional and emerging domains of engineering, as well as encouraging the next generation of leading researchers. Kedar leads a team responsible for managing many research areas and policy

interventions. Synthetic Biology is a priority area within EPSRC and is deliberately led through the Engineering Theme, recognising the importance of scale-up and the potential for industrialisation. Prior to his current role, he led the Cross-disciplinary Interfaces Programme, successfully introducing a number of creative initiatives within EPSRC. Previous roles also include being Head of the Life Sciences Interface Programme and being a portfolio manager in the Chemistry and Engineering programmes.

Sean McDonagh, Siemens UK Sean manages the Chemical & Pharmaceutical sales team, and leads regional strategic development of Siemens Chemical business. Working closely with the Global Chemical Sector HQ advising on the industry challenges faced by UK & Irish manufacturers, OEM`s & engineering businesses, helping Siemens develop value based solutions & technologies for clients.

Opening Address Speakers

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Plenary Speakers Jeroen van der Veer, Former CEO, Shell Chairman of the Supervisory Boards of Koninklijke Philips Electronics N.V. and of ING Group N.V. Shell: Non-executive Director (2009 - 2013), Chief Executive (2004 - 2009) Shell Canada Limited: Director (2003 -2005) Royal Dutch Petroleum Company: President (2000 - 2003), Managing Director (1997 - 2000) As Chief Executive Jeroen led Shell through major change, simplifying governance and organization, while clarifying

accountabilities. In 2009-2010 Jeroen was Vice-Chairman of a group of experts who advised for a new Strategic Concept for NATO. He was World President of the Society of Chemical Industry from 2002 to 2004. From 2000-2004 he served as a supervisory board member of The Dutch Central Bank. He is Advisor to Oman since 2009. He chaired ‘Platform Beta Techniek’, a governmental institute promoting education in science and technology from 2009 – 2011. He was Vice-Chairman and Senior Independent Director of Unilever (which includes Unilever N.V. and Unilever plc) to May 2011. In October 2012 he became Chairman of the Rotterdam Climate Initiative. As of July 1st 2013 Jeroen became Chairman of the Supervisory Council of the Technical University of Delft (Raad van Toezicht TU Delft). Jeroen also has various roles in several foundations and charities.

Professor Ray Allen, FIChemE, FREng, C Sci, University of Sheffield In 1995 Ray was the founding head of the new Department of Chemical & Process Engineering. He spun off Chemical and Process Engineering as an independent Department, doubled staff numbers, decided upon our major lines of research and so laid the foundations for much of the current research programme. My personal research interests began with environmental engineering and now straddle microfluidics, green chemical processes the hydrogen economy and Carbon Dioxide Utilization (CDU). My main focus lies at the chemistry/chemical engineering

interface with the aim of developing novel reactors and energy processes. This has included microfluidic devices and projects associated with lab-on-a-chip, plant-on-a-chip and high throughput screening. Nowadays, this microchemical engineering has been increasingly supplemented by work on larger scale energy producing processes, including Thermochemical Cycles and CDU, for massive scale production of hydrogen respectively to fuel the Hydrogen economy and to provide low carbon routes to transport fuels. Such work focuses on atom efficient chemical engineering processes that are often cyclic. In the case of a thermodynamically adverse reaction such as splitting water to manufacture hydrogen, only water and heat are put into the process and only hydrogen and oxygen are removed. The cycles under study include Sulphur Iodine, Copper chlorine and the Westinghouse hybrid sulphur process. We have a world leading research group in these technologies and our collaborations spread across a broad range of countries including France, Spain, Germany, the US and South Africa. More recently we have been working, under the auspices of 4CU, an EPSRC Programme Grant, on the conversion of CO2 to fuels where my particular focus has been on whole process studies and plasma reactors.

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Biological Engineering Seminar Speakers Chair : Dr Mark Dickman, University of Sheffield Modern medicine increasingly considers disease in the context of a misfunctioning complex biological system. To address this complexity much of my research involves interactions with colleagues in the Medical/Science faculty to bring an engineering approach to understanding disease. My research focuses on the development and application of analytical techniques to study biological systems, in particular, biological mass spectrometry in conjunction with bioseparations, which have been utilised to study a wide variety of biological systems. Using these

analytical approaches we are interested in identifying and characterising biopharmaceuticals, including oligonucleotide therapeutics and protein therapeutics. In addition, these tools are used to analyse protein post translational modifications and RNA post transcriptional modifications.

Professor Nicholas Turner, University of Manchester. My research interests encompass a broad range of biocatalysts, with particular emphasis on using directed evolution technologies to develop enzymes that have enhanced properties and stability when used on larger scale for preparative applications. We are particularly interested in the development of multi-enzyme and also chemo-enzymatic processes in which two or more bio-/chemo-catalysts are

combined. Our work in this area has recently begun to yield major benefits, e.g. in the application of monoamine oxidases for the enantioselective desymmetrisation of a key building block for the synthesis of telaprevir (treatment for hepatitis C).

Professor Kenneth F. Reardon, Professor and Jud and Pat Harper Chair of Chemical and Biological Engineering, Colorado State University Bioenergy, Biofuels, Biorefining Biosensors Environmental Biotechnology Biomedical Engineering Systems Biology, Proteomics, Metabolic Engineering

Most of Ken’s work is environmental biotechnology, particularly bioremediation, to improve our understanding of microbial degradation of hazardous compounds (often with the use of molecular biological and proteomic methods) and to develop better processes for cleanup of

contaminated air, water and soil. Dr Steve Pearson, Head of Business & Strategy, Industrial Biotechnology & Biorefinery Business Unit , Centre for Process Innovation I currently shape and deliver CPI's strategy to generate and facilitate large and small scale projects to progress the development of resource efficient manufacturing and the bioeconomy in the UK. I am a PhD qualified molecular biologist who has a broad understanding of molecular and cellular processes and technologies. Extensive process development and scale-up knowledge has been developed during my time at CPI.

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Education, Outreach & Training Seminar Speakers

Chair : Dr Martin Pitt, IChemE Liaison Officer, Design Teaching Coordinator , University of Sheffield

University of Sheffield: Senate Award for Excellence in Learning and Teaching 2013

Institution of Chemical Engineers: Morton medal for Excellence in Chemical Engineering Education 2012

Royal Academy of Engineering: ExxonMobil for Excellence in Teaching 2010

Dr Jarka Glassey, Reader in Chemical Engineering Education, Newcastle University

IChemE Council member – academic portfolio Chair of EdSIG committee Coordinator of iTeach - an EU funded project on effectiveness of core

chemical engineering knowledge and employability competencies teaching

Extensive research on student engagements and participation Dr Eva Sorensen, Professor in Chemical Engineering and Deputy Head of Department (Education), University College London

FHEA and ExxonMobil Teaching Fellow Educations interests within e-learning, problem- & project-based

learning, peer assessment Research interests within fluid separations

EPSRC Support for People: Leadership & Fellowships Speakers Kedar Pandya, Lead, Engineering Capability Theme Ruqaiyah Patel, Portfolio Manager : Complex Fluids and Rheology, Particle Technology, and Water Engineering.

Luke Davis, Portfolio Manager : Process Systems, Components and Integration, and Synthetic Biology

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Food & Water Security Seminar Speakers

Chair : Professor Catherine Biggs, University of Sheffield

Research interests Biofilms – using a multidisciplinary approach for characterisation

and control of bacterial adhesion and aggregation. Microbiology in urban water systems – using advanced molecular

microbiological techniques to determine who is there, what are they doing, what is the engineering impact?

Environmental proteomics – studying the microbial response to stresses in the natural and urban environment.

Synthetic biology and the water industry – developing solutions for urban water challenges.

John McGagh, Former Head of Innovation, Rio Tinto Group, Visiting Professor, SMI Centre for Water in the Minerals Industry John has significant experience delivering large scale business improvement, business change in the areas of Applied Industrial Technology & Innovation and Global Supply Chain and Procurement. A skilled motivator and communicator with an international perspective having lived and worked in Australia, USA and Europe

whilst being responsible for leading the establishment of facilities and transacting substantial business in Europe, Southern Africa, China, India, North and South America.

Professor David Butler, Director of the Centre for Water Systems at Exeter, Chair of the IWA/IAHR Joint Committee on Urban Drainage, EPSRC Established Career Fellow, University of Exeter David specialises in urban water management, including sustainable and resilient water systems, integration and control and water-energy-carbon interactions. David has authored / co-authored over 250 published papers, in addition to 12 books (including an internationally adopted graduate text book on Urban Drainage), published reports and edited conference proceedings. His research has been funded

continuously by EPSRC since 1995 including a major multi-disciplinary research project entitled Water Cycle Management for New Developments (WaND).

Dr Constantijn Sanders, Group leader Powder Science & Encapsulation,

Nestlé PTC Konolfingen

Constantijn completed his PhD at the University of Sheffield in 2005 in pharmaceutical High Shear Granulation processes, whilst working in the Product Development Group at Organon, Akzo Nobel. After completing his PhD, Constantijn joined the University of California Santa Barbara, to develop control strategies for agglomeration processes together with colleagues at IFPRI, Procter and Gamble and the University of Queensland. In 2009 he joined Grassa! as pilot plant manager and R&D coordinator to refine grass into useful ingredients such as protein for feed

and food, fibre for paper and packaging and minerals and water for returning to the soil. Constantijn joined Nestlé in 2012.

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Increased Manufacturing Value Seminar Speakers Chair : Dr Mark Ogden, University of Sheffield

Research Interests Spent nuclear fuel reprocessing Solvent extraction and ion exchange Novel separation processes including that with ionic liquids Supercritical fluids in separation processes Actinide speciation Dr Teodora Retegan, Chemistry and Chemical Engineering, Nuclear Chemistry/Industrial Materials Recycling, Chalmers University of Technology

Teodora's competence area is solvent extraction of metals, primarily from spent nuclear fuel for separation of actinides from lanthanides for further transmutation. She is also developing competence in safety related issues for Gen IV systems. Other application of her competence area is in recovery or recycling of valuable metals (platinum group metals, lanthanides, etc) from different sources, like electronic waste (WEEE).

Dr Chris Tighe, Imperial College London

Dr Tighe joined the Department as a Lecturer in December 2014, following a varied career spanning 15 years in both academic and contract R&D, and the process industries. The High Pressure Industrial Systems (HiPIS) research group will address challenges related to chemistry, scale-up and engineering materials in industrial processes at high pressure (typically 200 to 2000 atmospheres and usually at elevated temperature) by conducting detailed fundamental experiments and employing computational methods where appropriate to yield deeper insights.

Professor David York, University of Leeds

David is a member of The Institute of Particle Science and Engineering (IPSE), a centre of excellence helping to improve quality of life by addressing the engineering science of particulate processes and products. Current activities are organised within the following areas: - Particulate measurement systems - Particulate systems modelling - Manufacture of advanced particulates

Emeritus Professor Julian Morris, Technical Director Centre for Process Analytics and Control Technology, University of Newcastle Julian is a former CEO and Non-Executive Director Bioinnovel Ltd, a member of the CPI Advisory Committee and a member of the CPI High Temperature Innovation Centre Technology Technical and Innovation Advisory Group, and a member of the NEPIC Innovation and Thrust Team. He was head of the Department of Chemical and Process Engineering from 1990 to 1995 and the first head of the new School of Chemical Engineering and Advanced Materials. His research interests include

process diagnostics and condition monitoring, process performance monitoring, Process Analytical Technologies, neural networks, and advanced process control and optimisation.

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Conference Dinner : Cutlers Hall, Church Street, S1 1HG

Dress code : smart casual, no jeans or trainers please.

Drinks reception : arrive from 7:30pm.

Dinner : served at 8:15pm, with a vegetarian menu provided for all per pre-ordered requests.

Drinks : Included in your menu is a half bottle of red, white or rosé wine, and sparkling water

or orange juice for non-drinkers. A cash bar is also available, providing local Sheffield real ales.

Entertainment: Piano recital by Wendy Allbutt, after dinner entertainment by Paul Pashley.

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Materials Innovation Seminar Speakers

Chaire : Dr Jon Howse, University of Sheffield Research interests Nanoswimmers Understanding Spin-Coating Polymer Vesicle Formation Phase separation in polymer blends

Dr Valeska Ting, University of Bath Valeska's research interests lie in the field of sustainable energies. She has extensive experience of a large range of experimental materials characterization techniques including X-ray and neutron diffraction, electron microscopy, thermogravimetric and spectroscopic analysis, gas sorption testing and physical properties testing. She has contributed to the design and development of equipment for in-situ neutron diffraction experiments as well as aiding in the development and testing of high

pressure gas sorption apparatus. Valeska is currently interested in exploring the possibility of enhancing the storage capacity of existing nanoporous hydrogen storage materials, creating materials for selective storage and sequestration of gases such as carbon dioxide and investigating novel drug delivery methods through development of active nanoscale systems.

Dr Mark Haw, University of Strathclyde I am a lecturer and Director of Teaching in Chemical and Process Engineering at the University of Strathclyde. My research group focusses on particulates, colloids and nanostructured materials. Of particular interest is how chemical engineering can borrow ideas from across the scientific spectrum, from living systems to geology, to create materials and processes that function on multiple scales, from nanometre to macroscopic. I am also keen on public engagement with research, having published a book on Brownian motion (and why life would be impossible without it) and creating

Strathclyde’s ReallySmallScience outreach team.

Dr Justin Tian, Queens University, Belfast Dr Justin Yiwei Tian is currently working as research fellow in Pharmaceutical Engineering group, School of Pharmacy, Queen’s University Belfast. He graduated in Macromolecular Materials and Engineering from Beijing Institute of Technology, China in 2006 and received his MSc in Chemical Process Engineering and PhD in Pharmaceutics in Queen’s University Belfast. His major research interests include fundamental understanding of phase separation, physicochemical characterisation and applications in pharmaceutical process.

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Meeting the Sustainable Energy Demand Seminar Speakers Chair : Professor Peter Styring, Director of EPSRC CO2Chem Network, University of Sheffield Research interests New materials for carbon dioxide capture Catalysts for carbon dioxide utilisation (CDU) Absorber and reactor intensification for CDU Process design for energy and economically efficient CDU Life Cycle Assessment in CDU

CDU Policy and Public Engagement Snowsports Tribology

John Bøgild Hansen, Senior Scientist, Haldor Topsøe John is Senior Advisor to Management in the Company Management of Haldor Topsøe A/S. He graduated with a MSc in Chemical Engineering from DTU in 1975 and has been employed by Haldor Topsøe since then. In 1979 he joined the Research & Development Division where he was Department manager from 1984. In 2000 he became Advisor to the chairman and founder, Dr. Haldor Topsøe. John Bøgild Hansen holds 24 patents and has made more than 60 publications. He has presented more than 30 invited key note lecturers on synthetic fuel production, fuel cells, solid oxide electrolysis and fuels from

biomass production.

Professor Paul Williams, Director of the Centre for Doctoral Training in Low Carbon Technologies, University of Leeds Research areas Waste and biomass pyrolysis, gasification and waste incineration. • Published >400 research papers, with 10,000 citations to his work Awarded ~£15M in research grants from EPSRC, EU, DEFRA, BIS

Dr John Newton, ITM Power Limited John gained his PhD. in Materials Engineering from Sheffield University and joined ITM Power in 2012 from RWE npower where he was CIO for the UK generation business. John has 20 years’ utility experience with a background in energy storage and was part of Regenesys Technologies, a company formed by National Power plc which developed a utility scale

energy storage technology based on redox flow batteries. From 2002 to 2008 John was an

independent assessor for the UK DTI New & Renewable Energy Programme.

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T: +44 (0) 114 222 7576 E: chemeng@sheffield.ac.uk www.shef.ac.uk/cbe Copyright of The University of Sheffield 2015