2008

C-C bond formationO 0282 Steric Tuning of Silylacetylenes and Chiral Phosphine Ligands for Rhodium-Cat-

alyzed Asymmetric Conjugate Alkynylation of Enones. — It is found that addition of the silylacetylene (III) to enones in the presence of the bulky phosphine (I) allows highly enantioselective formation of β-alkynylketones. These ketones are important building blocks. — (NISHIMURA*, T.; GUO, X.-X.; UCHIYAMA, N.; KATOH, T.; HAYASHI, T.; J. Am. Chem. Soc. 130 (2008) 5, 1576-1577; Dep. Chem., Grad. Sch. Sci., Kyoto Univ., Sakyo, Kyoto 606, Japan; Eng.) — Jannicke

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