Myth or Truth?THE BENEFITS OF

COFFEE REVALED!!!!

A little on HISTORY of COFFEE

Ethiopia Egypt South Arab

IndiaEuropeAmerica

Most CommonDisadvantage

Known by everyone

CAFFEINE

CAFFEINE CHMEMISTRY

•Found in beans, leaves, fruits• Natural Pesticide•Consumed by human •CNS stimulant•Physcoactive Substances

HOW MUCH

IS TOO

MUCH?

Caffeine MechanismCaffeine

Molecules Dehydration

ADH

Increase in release of

water

Increase in urination

Pitutary Gland

Inhibits adenosine

Coffee as Antioxidant

Substance in coffee that acts as antioxidants

Polyphenols Flavonoids Proanthocyanidins Cinnamic acids Quinines Trigonelline

SUBSTANCE IN COFFEE THAT ACTS AS ANTIOXIDANTS

Polyphenols Flavonoids Proanthocyanidins Cinnamic acids Quinines Trigonelline

LIST OF CANCER'S RISK THAT CAN BE REDUCED

Oesophageal cancer Liver cancer Oral cavity/ Pharynx cancer Non-hormone receptive breast cancer

REFERENCES http://edition.cnn.com/2010/HEALTH/04/28/coffee.studies/in

dex.html http://www.coffeeandhealth.org/research-centre/cancer/conc

lusion/ http://www.buzzle.com/articles/antioxidants-in-coffee.html http://coffeescience.org/antioxidant

Happiness Booster

The answer lies with

DOPAMINE

What is Dopamine?

a neurotransmitter that activates pleasure centers in certain parts of the brain

helps regulate movement and emotional responses, motivate us

How?

caffeine increases level of dopamine (released from prefrontal cortex)

causes reabsorption of dopamine in the body to be slower

A deficiency of dopamine is likely responsible for the loss of pleasure and motivation found in major depression

Parkinson Diseasea disorder of the brain that

leads to shaking (tremors) and difficulty with walking, movement, and coordination.

participants who carried types of a specific gene — called GRIN2A — received neuroprotective benefits from coffee against Parkinson’s

Caffeine act as antagonist to the A2A receptor, blocking its binding site, rendering it inactive

Made on mice. Inject MPTP to mice pre-treated with caffeine

Recent Research shows:

Extra:

Why don’t you feel sleepy after taking coffee?

Woke up >> neurons produce

adenosine >> adenosine receptor at CNS monitor the action >> caffeine as a block of

wood >> bind at there and doesn’t activate the

receptor >> no stimulant will be

send to brain

Improve on Short-Term

Memory

TWO TYPES Working memory Short-term storage memory

THE STUDIES Some of the studies indicate that drinking coffee can improve short term memory Reaction times Reverse symptoms of Alzheimer's disease Regular consumption of caffeine

How it may work?

• Adenosine and Caffeine• Improving alertness temporarily• Increased neuron firing

HOW IT MAY WORK? Adenosine and Caffeine Improving alertness temporarily Increased neuron firing

• Adrenal gland –produces adrenaline

Adrenal gland –produces adrenaline

Increased Attention andMemory Performance

Feel Fresh and not Sleepy

Decreased Risk of Heart disease

Increased physical performance

Decreased Risk of Liver Disease

Effect of Moderate Caffeine Consumption