epidemiologyandoutcomesofheadinjurypaents ... ·...

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Characteris*cs Overall, 204 pa-ents with head injury were enrolled; 53 (26.0%) had mul-system trauma. Most head injuries occurred in 16 30 yrs old (51.0%) and men (86.8%). Road traffic accidents (RTA’s) were responsible for the majority of head injuries (40.2%); pedestrians struck being the most common (overall 24.5%). Other mechanisms included: assault with blunt injury (38.2%) or penetra-ng injury (2.5%) and falls (17.7%). Head Injury Severity and Outcomes Overall head injury severity (as per the Glasgow Coma Scale (GCS)) on presenta-on was: 108 pa-ents had mild injury (GCS 1315; 53.0%), 39 with moderate (GCS 912; 19.1%), and 51 with severe (GCS 38; 25.0%). Overall, 21 pa-ents died (10.3%). The majority (62.6%) of deaths occurred within 48 hours of admission to the emergency department. Risk factors associated with mortality are seen in Table 2. These highlight the severity of clinical presenta-on among those pa-ents with mortality – including severe GCS, bilateral fixed pupils and hypoxia. Epidemiology and outcomes of head injury pa;ents in an urban Ethiopian emergency department M. Landes 1,4,5 , R Venugopal 1,4,5 , S. Berman 4,5 , A. Azazh 3,5 Head injury is a leading cause of mortality from trauma in low to middle income countries. Ethiopia is in the early stages of developing prehospital, emergency and cri-cal care services Addis Ababa University’s (AAU) Tikur Anbessa Specialized Hospital (TASH) is a neurosurgical and trauma referral center and the largest general public hospital in Ethiopia. The Emergency Department treats approximately 80,000 pa-ents per year in a low resourced working environment. The first Emergency Medicine residency was started at Addis Ababa University in 2010 and has since graduated the first four emergency medicine doctors in October of 2013. The objec-ve of this study was to characterize the epidemiology and outcomes of head injury at a large urban academic hospital with a newly ac-ve emergency medicine program in Ethiopia. 1 Division of Emergency Medicine, Department of Family and Community Medicine, Toronto, Ontario; 2 Division of Emergency Medicine, Department of Medicine, University of Toronto; 3 Department of Emergency Medicine, School of Medicine, Addis Ababa University; 4 University Health Network, Toronto, Ontario; 5 Toronto Addis Ababa Academic Collabora-on in Emergency Medicine We report a high prevalence of severe clinical presenta-ons and mortality among a prospec-ve cohort of head injured pa-ents in a large urban emergency department in Ethiopia. Road traffic accidents cons-tute a large propor-on of head injuries presen-ng to this emergency department, and reflects the high burden of road traffic related trauma in lowresource seengs. Head injury afer trauma represents a significant risk of morbidity and mortality in this seeng in Ethiopia, for which the ongoing development of emergency and surgical services may improve outcomes Appropriate iden-fica-on and services for pa-ents at risk of mortality may guide this con-nued development. We conducted a prospec-ve cohort of all head injured (including both isolated head injury and mul-system trauma with head injury) pa-ents over 4 months presen-ng to the Emergency Department of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Using a standardized data collec-on form, demographic and clinical informa-on was extracted from the pa-ent’s chart, radiology reports and/or opera-ve reports. Pa-ents were followed un-l they reached one of the following endpoints: discharge, referral to another hospital, death, or 7 days in the hospital. Consent for study par-cipa-on was obtained from the pa-ent or subs-tute decision maker. Support for this study was from a grant from the University Health Network Emergency Department Prac-ce Plan, the Department of Family and Community Medicine at the University of Toronto and the Interna-onal Development Research Centre (Canada). *Table 2. Mul;variate analysis of risk factors for mortality * N=170 includes pa-ents not transferred with known outcomes ** Measured on presenta-on Table 1. Pa;ent Characteris;cs on Presenta;on and Outcomes by Mechanism of Injury

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Page 1: Epidemiologyandoutcomesofheadinjurypaents ... · Head!injury!is!aleading!cause!of!mortality!from!traumain!low!to! middleincome countries.!!! Ethiopiais!in!the!early!stages!of!developing!preEhospital,!

Characteris*cs  Overall,  204  pa-ents  with  head  injury  were  enrolled;  53  (26.0%)  had  mul-system  trauma.          Most    head  injuries  occurred  in    16  -­‐30  yrs  old  (51.0%)  and  men  (86.8%).          Road  traffic  accidents  (RTA’s)  were  responsible  for  the  majority  of  head  injuries  (40.2%);  pedestrians  struck  being  the  most  common  (overall  24.5%).      Other  mechanisms  included:  assault  with  blunt  injury  (38.2%)  or  penetra-ng  injury  (2.5%)  and  falls  (17.7%).        Head  Injury  Severity  and  Outcomes    Overall  head  injury  severity  (as  per  the  Glasgow  Coma  Scale  (GCS))  on  presenta-on  was:  108  pa-ents  had  mild  injury  (GCS  13-­‐15;  53.0%),  39  with  moderate  (GCS  9-­‐12;  19.1%),  and  51  with  severe  (GCS  3-­‐8;  25.0%).        Overall,  21  pa-ents  died  (10.3%).    The  majority  (62.6%)  of  deaths  occurred  within  48  hours  of  admission  to  the  emergency  department.          Risk  factors  associated  with  mortality  are  seen  in  Table  2.    These  highlight  the  severity  of  clinical  presenta-on  among  those  pa-ents  with  mortality  –  including  severe  GCS,  bilateral  fixed  pupils  and  hypoxia.      

Epidemiology  and  outcomes  of  head  injury  pa;ents    in  an  urban  Ethiopian  emergency  department  

 

M.  Landes1,4,5,  R  Venugopal1,4,5,  S.  Berman4,5,  A.  Azazh3,5    

Head  injury  is  a  leading  cause  of  mortality  from  trauma  in  low  to  middle  income  countries.      Ethiopia  is  in  the  early  stages  of  developing  pre-­‐hospital,  emergency  and  cri-cal  care  services  •  Addis  Ababa  University’s  (AAU)  Tikur  Anbessa  Specialized  

Hospital  (TASH)  is  a  neurosurgical  and  trauma  referral  center  and  the  largest  general  public  hospital  in  Ethiopia.  The  Emergency  Department  treats  approximately  80,000  pa-ents  per  year  in  a  low  resourced  working  environment.  

•  The  first  Emergency  Medicine  residency  was  started  at  Addis  Ababa  University  in  2010  and  has  since  graduated  the  first  four  emergency  medicine  doctors  in  October  of  2013.    

 The  objec-ve  of  this  study  was  to  characterize  the  epidemiology  and  outcomes  of  head  injury  at  a  large  urban  academic  hospital  with  a  newly  ac-ve  emergency  medicine  program  in  Ethiopia.    

1Division  of  Emergency  Medicine,  Department  of  Family  and  Community  Medicine,  Toronto,  Ontario;  2Division  of  Emergency  Medicine,  Department  of  Medicine,  University  of  Toronto;  3Department  of  Emergency  Medicine,  School  of  Medicine,  Addis  Ababa  University;    

4University  Health  Network,  Toronto,  Ontario;  5Toronto  Addis  Ababa  Academic  Collabora-on  in  Emergency  Medicine      

We  report  a  high  prevalence  of  severe  clinical  presenta-ons  and  mortality  among  a  prospec-ve  cohort  of  head  injured  pa-ents  in  a  large  urban  emergency  department  in  Ethiopia.          Road  traffic  accidents  cons-tute  a  large  propor-on  of  head  injuries  presen-ng  to  this  emergency  department,  and  reflects  the  high  burden  of  road  traffic  related  trauma  in  low-­‐resource  seengs.          Head  injury  afer  trauma  represents  a  significant  risk  of  morbidity  and  mortality  in  this  seeng  in  Ethiopia,  for  which  the  ongoing  development  of  emergency  and  surgical  services  may  improve  outcomes      Appropriate  iden-fica-on  and  services  for  pa-ents  at  risk  of  mortality  may  guide  this  con-nued  development.    

We  conducted  a  prospec-ve  cohort  of  all  head  injured  (including  both  isolated  head  injury  and  mul-system  trauma  with  head  injury)  pa-ents  over  4  months  presen-ng  to  the  Emergency  Department  of  Tikur  Anbessa  Specialized  Hospital,  Addis  Ababa,  Ethiopia.      Using  a  standardized  data  collec-on  form,  demographic  and  clinical  informa-on  was  extracted  from  the  pa-ent’s  chart,  radiology  reports  and/or  opera-ve  reports.        Pa-ents  were  followed  un-l  they  reached  one  of  the  following  endpoints:  discharge,  referral  to  another  hospital,  death,  or  7  days  in  the  hospital.        Consent  for  study  par-cipa-on  was  obtained  from  the  pa-ent  or  subs-tute  decision  maker.    

Support  for  this  study  was  from  a  grant  from  the  University  Health  Network  Emergency  Department  Prac-ce  Plan,  the  Department  of  Family  and  Community  Medicine  at  the  University  of  Toronto  and  the  Interna-onal  Development  Research  Centre  (Canada).      

*Table  2.    Mul;variate  analysis  of  risk  factors  for  mortality    

*N=170  includes  pa-ents  not  transferred  with  known  outcomes  **Measured  on  presenta-on  

Table  1.  Pa;ent  Characteris;cs  on  Presenta;on  and  Outcomes  by  Mechanism  of  Injury