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    FISIOLOGI

    SISTEM

    RESPIRASI

    Carolin

    IndraNovyan

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    Function of the

    Respiratory System• Gas exchanges (O2 & CO2)

    between the bloo an externalen!ironment

    • "xchange of gasses ta#es placewithin the lungs in the al!eoli(onlysite of gas exchange$ otherstructures passageways

    • %assageways to the lungs purify$warm$ an humiify the incomingair 

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    Organs of the Respiratory

    system

    • ose

    • %harynx

    'arynx• rachea

    • ronchi

    'ungs *al!eoli

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    Figure +,-2

    .pper Respiratory ract

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     /natomy of the asal

    Ca!ity• Olfactory receptors locate in mucosa on

    the superior surface

    • he rest of the ca!ity is line with

    respiratory mucosa

     moistens air$ trapsincoming foreign particles

    • 'ateral walls ha!e pro0ections calleconchae

      F1 3 4 surface area3 4 air turbulence within the nasal ca!ity)

    • he nasal ca!ity is separate from the oralca!ity by palate

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    %aranasal Sinuses

    • Frontal bone

    • Sphenoi bone

    • "thmoi bone

    • 5axillary bone

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    Function of the sinuses

    • 'ighten the s#ull

    •  /ct as resonance chambers forspeech

    • %rouce mucus that rains into thenasal ca!ity

    %/R//S/' S6.S"S

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    %harynx (hroat)

    • 5uscular passage from nasalca!ity to larynx

    • hree regions of the pharynx

    • asopharynx

    • Oropharynx

    • 'aryngopharynx

    • he oropharynx an

    laryngopharynx are commonpassageways for air an foo

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    Figure +,-2

    .pper Respiratory ract

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    'arynx• Routes air an foo into proper channels

    • %lays a role in speech

    5ae of eight rigi hyaline cartilages an a spoon3shape flap of elastic cartilage(epiglottis)

    Structure of the Larynx• hyroi cartilage

    • "piglottis

    • 7ocal Cor

    • Glottis

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    rachea

    • Connects larynx with bronchi

    • 'ine with ciliate mucosa

    •eat continuously in the oppositeirection of incoming air 

    •"xpel mucus loae with ust an otherebris away from lungs

    • 8alls are reinforce with C3shapehyaline cartilage

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    %rimary ronchi

    •Forme by i!ision of the trachea

    •"nters the lung at the hilus

    •Right bronchus is wier$ shorter$an straighter than left

    •ronchi subi!ie into smaller

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    'ungs

    • Occupy most of the thoracic ca!ity

    • /pex is near the cla!icle (superiorportion)

    •ase rests on the iaphragm (inferiorportion)

    •"ach lung is i!ie into lobes byfissures

    •'eft lung * two lobes

    •Right lung * three lobes

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    'ungs

    Figure

    +,-9b

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    Co!erings of the 'ungs

    • %ulmonary (!isceral) pleuraco!ers the lung surface

    • %arietal pleura lines the wallsof the thoracic ca!ity

    %leural flui fills the areabetween layers of pleura toallow gliing

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    Respiratory ree :i!isions

    • %rimary bronchi

    Seconary bronchi• ertiary bronchi

    • ronchioli

    • erminal bronchioli

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    ronchioles

    Figure

    +,-;a

    • Smallest branches

    of the bronchi•  /ll but the smallest

    branches ha!ereinforcing cartilage

    • erminalbronchioles en inal!eoli

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    Respiratory

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     /l!eoli

    •Structure of al!eoli•  /l!eolar uct

    •  /l!eolar sac

    •  /l!eolus

    •Gas exchange

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    Respiratory 5embrane

    (/ir3loo arrier)

    hin s=uamous epithelial layerlining al!eolar walls

    • %ulmonary capillaries co!er

    external surfaces of al!eoli

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    Respiratory 5embrane

    (/ir3loo arrier)

    Figure

    +,->

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    Gas "xchange

    • Gas crosses the respiratory membrane byiffusion

    •Oxygen enters the bloo

    •Carbon ioxie enters the al!eoli

    • 5acrophages a protection

    • Surfactant coats gas3expose al!eolarsurfaces

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    "!ents of Respiration

    • %ulmonary !entilation * mo!ing air in an out ofthe lungs

    • "xternal respiration * gas exchange between

    pulmonary bloo an al!eoli

    • Respiratory gas transport * transport of oxygenan carbon ioxie !ia the bloostream

    • 6nternal respiration * gas exchange betweenbloo an tissue cells in systemic capillaries

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    Mekanisme Pernapasan

    Inhalasi (proses aktif)→ udara masuk  Gas berpindah dari tempat yang

    bertekanan tinggi ke tempat yang

    bertekanan rendah Selama inspirasi → diafragma

    terdorong ke bawah dan paru-paru

    mengembang Pada waktu paru-paru mengembang, volume meningkat → tekanan dlmparu-paru menurun

    ekanan dalam paru lebih rendah

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    Respirasi

    "espirasi eksternal → pertukaran %&dan '%& antara permukaan respirasidan darah

    "espirasi internal → pertukaran %&dan '%& antara darah dan sel-seltubuh

    "espirasi seluler → proses dimanasel-sel menggunakan %& untukmemproduksi P

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    Respirasi Eksternal

    Pertukaran %& dan '%& antara

    alveolus dan darah ekanan parsial %& lebih tinggi

    dalam alveolus daripada dalamdarah → %& berdifusi ke dalam darah

    ekanan parsial '%& lebih tinggi

    dalam darah daripada dalamalveolus → '%& bergerak masuk ke

    alveolus pada arah yang berlawanan

    dan diekshalasikan ke luar

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    Respirasi Internal

    Pertukaran %& dan '%& antara darah

    dan *aringan ekanan %& lebih tinggi dalam darah

    daripada dalam *aringan → %& keluarke dalam *aringan

    ekanan '%& lebih tinggi dalam

     *aringan daripada dalam darah →'%& berdifusi dgn arah berlawanan

    ke dalam darah

    '%& merupakan produk buangan

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    Kontrol Pernapasan

    Pernapasan diatur oleh pusatpernapasan dalam medulla otak 

    +edulla merangsang otot-ototpernapasan

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    Kontrol Pernapasan

    aktor yang palingpenting yangmempengaruhi pusatpernapasan adalah '%&

    Peningkatan '%& arteri→ meningkatkankeasaman 'S

    Peningkatan keasaman

    'S dideteksi olehsensor p dimedulla +edulla meningkatkan

    ke.epatan dankedalaman respirasi

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    Pertukaran Gas

     tmos/r bumi terdiri dari 012 3 dan &42%&

    Paru-paru sehat mempunyai 566 *uta

    alveolus b dapat mengikat 7 molekul %&  8ang ter*adi pada udara yang kita hirupGS I39!: !;9!:

    %& &6042 47

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    LUNG VOLUMES

    ial 7olume (7)

      he amount of air that mo!es into lungs

    with each inspiration or the amount that

    mo!es out with each expiration;?? ml

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    LUNG VOLUMES

      6nspiratory Reser!e 7olume (6R7)

    he air inspire with a maximal inspiratory

    effort

     ,??? ml

      "xpiratory Reser!e 7olume ("R7)

    he !olume expelle by an acti!eexpiratory effort after passi!e expiration

     +2?? ml

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    RESIDUAL VOLUME

      Resiual 7olume (R7)

    he air left in the lungs after a maximal

    !oluntary expiratory effort

    (a!oiing collaps of the lungs)

     +2?? ml @ FRC * "R7

      Functional resiual capacity (FRC)he !olume of gas present in the lung at

    en expiration uring tial breathing-

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    LUNG CAPACITY

      otal lung capacity ('C) is the !olume

    of gas in the lungs after maximal

    inspiration$ or the sum of all !olume

    compartments-

      otal 'ung Capacity

      7 A 6R7 A "R7 A R7 ;B?? ml

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    LUNG CAPACITY

      6nspiratory Capacity

    6R7 A 7 ,;?? ml

      Functional Resiual Capacity"R7 A R7 29?? ml

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    VITAL CAPACITY

      7ital Capacity  he largest amount of air that can be expire after a maximal

    inspiratory effort$ (fre=uently measure as an inex ofpulmonary function)

     9?? ml  7ital capacity (7C) is the !olume change at the mouth

    between the positions of full inspiration an complete

    expiration-

     

    Gi!es useful information about the strength of respiratorymuscles an other aspects of pulmonary function-

      Force 7ital Capacity (F7C) 5aximal inspiration followe by

    maximal exhale as fast as possible

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    VITAL CAPACITY

    he measurement may be mae in one of the following ways

    +- 6nspiratory !ital capacity (67C) the measurement is

    performe in a relaxe manner$ without unue haste or

    eliberately holing bac#$ from a position of full expiration

    to full inspiration-

    2- "xpiratory !ital capacity ("7C) the measurement is

    performe in a relaxe manner$ without unue haste or

    eliberately holing bac#$ starting from a position of full

    inspiration to full expiration-

    ,- Force !ital capacity (F7C) the !olume of gas which isexhale uring a force expiration starting from a position

    of full inspiration an ening at complete expiration-

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    Respiratory !olumes as isplaye by a spirometer- 7olumes shown are those of

    a typical ault male

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    RESPIRATORY DEAD

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    RESPIRATORY DEAD

    SPACE  Respiratory ea space

    he space in the conucting Done of airways

    occupie by gas that oes not exchange with

    bloo in the pulmonary !essels-

      6t plays no role in remo!ing CO2 from the boy or

    aing O2-

      6mportant in humiification of inspire gas an in

    temperature conser!ation-

      7olume can be estimate as + ml1lb boy weight-

    For an a!arage ? #g man$ 7: @ ? x 2$2 x + E

    +;? ml