Looking beyond the gluten-free diet: the positive impact of supplements

Dr. Alexander Shikhman MD, PhD, FACRGluten-Free Remedies™

The most common food-driven autoimmune disease affecting humans

10 to 35% of general population

The mortality rate in people with gluten intolerance exceeds the general population by a factor of 1·9–3·8

Gluten-free diet is protective against malignant diseases after 1–5 years

Focus on Gluten Intolerance

Why Gluten? Human digestive enzymes cannot completely digest gluten

in the gastrointestinal tract

Consumption results in formation of large protein fragments stimulating inflammatory reaction within the intestinal wall

Gluten peptides can penetrate in systemic circulation and trigger immune responses in internal organs distant from the intestine (thyroid gland, salivary glands, brain etc)

Celiac disease 3-5%

Gluten intolerance without celiac disease

30-35%

Latent gluten intolerance HLA DQ2 or DQ8 +

without clinical symptoms60-70%

35-40% will develop gluten

intolerance during their lifetime

60-70%will be

affectedby

rheumatic,metabolic and

chronicinflammatory

diseases

Spectrum of Gluten Intolerance

Metabolic Problems Associated with Gluten Intolerance

Malabsorption Of VitaminsVitamins A, D, E And KVitamins B1, B2, B6, Folic Acid

Pernicious AnemiaIron DeficiencyZinc DeficiencyCopper DeficiencySelenium Deficiency

Rheumatic Diseases Commonly Associated with Gluten Intolerance

GLUTEN INTOLERANCE

SJOGREN’S SYNDROM

E

FIBROMYALGIA

PSEUDOGOUT

OSTEOPOROSIS

SACROILIITIS

DERMATOMYOSITIS

PSORIASIS/PSORIATIC ARTHRITIS

Nonrheumatic Diseases Commonly Associated with Gluten Intolerance

IRRITABLEBOWL

SYNDROME

DERMATITISHERPETIFORMI

S

CELIACDISEASE

AUTISM

BIPOLARDISORDER

SECONDARY

HYPERPARA-THYROIDISM

ADHD PERIPHERAL

NEUROPATHY

SEIZURE DISORDER

SCHIZOPHRENIA

CHRONIC FATIGUE

SYNDROME

Treatment of Gluten Intolerance

ELIMINATION

OF GLUTEN

CORRECTIONOF

METABOLICDISORDERS

CORRECTIONOF IMMUNERESPONSES

TUMORSURVEILLANC

E

Herbs and Food Supplements in Therapy of Gluten Intolerance

WHY:

• Excellent safety profile and biocompatibility• Broad range of efficient concentrations• Varied choices compared to prescription drugs• Natural targeting of specific biochemical pathways

Herbs and Food Supplements in Therapy of Gluten Intolerance

THE NECESSITIES:

Multivitamins and Minerals Digestive Enzymes Probiotics Prebiotics Omega-3-Fatty Acids (Fish or Krill Oil) Black Currant Seed Oil Sodium Butyrate L-Glutamine

Prevention and Correction of Osteopenia and Osteoporosis

Vitamin DCalcium (Calcium Lactate)Magnesium (Magnesium Citrate)Strontium CitrateVitamin KBiotinOrganic SilicaL-Lysine

Skin, Hair and Nail SupportThinning and loss of hair, acne, loss of skin elasticity and brittle nails are commonly seen in people with gluten intolerance and celiac disease.

COMMON MECHANISMS:Iron deficiencyBiotin deficiencySelenium deficiencyHypothyroidismAutoimmune diseases

Supplements for Skin, Hair and Nails

BiotinIron MultivitaminsEclipta AlbaRubia cordifolia

Hyaluronic AcidCollagen Type 2L-ProlineSelenium

Skin and Mucosal DrynessOne of the first manifestations of Sjogren’s Syndrome

PRINCIPLES OF CORRECTION:N-Acetyl CysteineAcetyl-L-CarnitineCordyceps SynensisArtemisia/Berberine BlendZinc/Elderberry LozengesBlis K12 Oral Probiotic

Restoration of Gut MicrofloraProfound changes in gut microflora persist for years even on a strict gluten-free diet.

PRINCIPLES OF CORRECTION:PrebioticsProbioticsDigestive EnzymesEpicorSodium ButyrateL-GlutamineBiofilzyme

Candida (Yeast) OvergrowthTypical symptoms include:BloatingCraving for sugarsHeadachesHivesEczemaScalp itchinessLoose stools

Supplements for Candida (Yeast) Overgrowth

Low carb dietPau D’arcoBlack Walnut HullsBerberineDigestive Enzymes

TriphalaNeemAnantamulRubia Cordifolia

Brain FogTriggering mechanisms:Adrenal insufficiencyAbnormal gut microorganisms and yeast overgrowthMalabsorbtion of vitamin and mineralsDepletion of nutrients Abnormalities in urea cycle Ineffective elimination of ammonia from the bloodstream

Supplements for Brain FogAcetyl L-CarnitineGotu KolaDMAESunflower LecithinL-methylfolateMethylcobalamine

SAMeTaurineSodium ButyrateRhodiolaEleutherococcus7-Keto

Supplements for Leaky Gut

ProbioticsPrebioticsEpicorBovine ImmunoglobulinsN-Acetylglucosamine

Alpha Lipoic AcidCoix Seed ExtractCitrulline MalateSodium ButyrateL-Glutamine

Increased intestinal permeability where food antigens, toxins and microorganisms leak into the bloodstream

Supplements for Accidental Gluten Consumption

N-Acetylglucosamine/Mannan Oligosaccharies: protect and regenerate intestinal mucosal lining

Yucca Schidigera: soap-like substance that eliminate gluten from the digestive tract and stimulate the growth of beneficial intestinal microorganisms

Triphala: increases peristaltic movement accelerating removal of gluten from the digestive tract

Supplements to Normalize Immune Responses

EpicorYucca Root ExtractBovine ImmunoglobulinsCoix Seed ExtractGermanium

ArabinogalactanProbioticsPrebioticsSerrazimesCordyceps Synensis

Supplements for Preventing Infections

Olive Leaf ExtractBlack Walnut HullsArtemisia/BerberineProbioticsPrebioticsL-LysineGermanium

EpicorBovine ImmunoglobulinsNeemAnantamulAshokaManjistha

Supplements for Stress Responses

RhodiolaEleutherococcusAcetyl-L-Carnitine7-KetoL-Methylfolate

Supplements for InflammationOmega-3 Fatty AcidsBlack Currant Seed OilBoswellia/CurcuminDevil’s ClawMSMN-AcetylglucosamineYucca Schidigera Extract

Keep In Touchglutenfreeremedies.com

facebook.com/gfremedies

@gfremedies

855-TAKE-GFR (855-825-3437)