neuro-ophthalmology - a cautionary tale

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A Cautionary Tale Dr Phillip Hayes GOSFORD AND WYONG EYE SURGERYD

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Giant Cell Arteritis

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Page 1: Neuro-ophthalmology - A cautionary tale

A Cautionary Tale

Dr Phillip HayesGOSFORD AND WYONG EYE SURGERYD

Page 2: Neuro-ophthalmology - A cautionary tale

Mrs JC 76 years old LTG diagnosed 2010 IOP R15 L17 Treated with Xalatan Nov 19 2013 RVA 6/9 LVA 6/9 IOP R13 L17

Page 3: Neuro-ophthalmology - A cautionary tale
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Page 5: Neuro-ophthalmology - A cautionary tale

PHx PMR Mentioned in passing “ eyes were

playing up” with visual disturbance on Left side 2 days previously and a “heavy” head

Complained to the Field Tester that she was having trouble with LE and felt Left field was worse.

Didn’t mention any other symptoms

Page 6: Neuro-ophthalmology - A cautionary tale
Page 7: Neuro-ophthalmology - A cautionary tale

Represented via GP 6 days later (25/11/13)

RVA NLP LVA vague HM R RAPD

Page 8: Neuro-ophthalmology - A cautionary tale

Mrs JC

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Page 10: Neuro-ophthalmology - A cautionary tale

Admitted immediately to Gosford Hospital

3 days IV 1gm Methyl Prednisolone ESR and CRP elevated 26/11/13 TABx: Positive Giant Cell

Arteritis Bilateral AAION with R CRAO Prognosis.....

Page 11: Neuro-ophthalmology - A cautionary tale

Bilateral Blindness happens

Page 12: Neuro-ophthalmology - A cautionary tale

Giant Cell Arteritis

Anterior Ischaemic Optic Neuropathy CRAO CN palsies Plus AMI, Dermal ischaemia,

Mesenteric ischaemia

Page 13: Neuro-ophthalmology - A cautionary tale

Beware to Stoic Little Old Lady with any of these 4› Amaurosis Fugax› New Headache› New Diplopia› Facial/Neck/ Mouth/Jaw Pain

Page 14: Neuro-ophthalmology - A cautionary tale

Transient Monocular Vision Loss

Amaurosis Fugax Fleeting (seconds to mins)painless

significant loss of vision in one eye Severe dimming/Blackout/curtain(partial

field loss) No aura and no neuro symptoms No persistence Exact nature of the symptoms and

associated symptoms Normal examination with no emboli

Page 15: Neuro-ophthalmology - A cautionary tale

History History History Monocular vision loss Recent onset of Diplopia New Headache Unwell, loss of appetite or weight or

night sweats or fever, muscle aches and pains

Face/mouth/tongue/jaw/ throat/ear eye/scalp ache

Scalp tenderness Other recent illness

Page 16: Neuro-ophthalmology - A cautionary tale

New Headache

Temporal Scalp and Temporal artery tenderness Can be diffuse and bifrontal New in character

Page 17: Neuro-ophthalmology - A cautionary tale

History History History Monocular vision loss Recent onset of Diplopia New Headache Unwell, loss of appetite or weight or

night sweats or fever, muscle aches and pains

Face/mouth/tongue/jaw/ throat/ear eye/scalp ache

Scalp tenderness Other recent illness

Page 18: Neuro-ophthalmology - A cautionary tale

Facial Pain Jaw claudication is only the classic

symptom Any ache from scalp to ear to neck Tongue pain with talking Throat with swallowing Ocular ischaemic pain with orbit or eye

pain on standing

Page 19: Neuro-ophthalmology - A cautionary tale

History History History Monocular vision loss Recent onset of Diplopia New Headache Unwell, loss of appetite or weight or

night sweats or fever, muscle aches and pains

Face/mouth/tongue/jaw/ throat/ear eye/scalp ache

Scalp tenderness Other recent illness

Page 20: Neuro-ophthalmology - A cautionary tale

Recent onset Diplopia

A new symptom Can be fleeting or persistent Vertical or Horizontal

Page 21: Neuro-ophthalmology - A cautionary tale

History History History Monocular vision loss Recent onset of Diplopia New Headache Unwell, loss of appetite or weight or

night sweats or fever, muscle aches and pains

Face/mouth/tongue/jaw/ throat/ear eye/scalp ache

Scalp tenderness Other recent illness

Page 22: Neuro-ophthalmology - A cautionary tale

Examination

Ocular exam usually normal Tender swollen Temporal artery Carotid auscultation Rarely signs of ocular ischaemia

› Dilated veins, retinal haemorrhages,uveitis› Corneal oedema

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Page 24: Neuro-ophthalmology - A cautionary tale

Be Suspicious!!!

What do you do if someone over 6o says in passing› Lost vision in one eye› New Headache› New Diplopia› Facial/Neck/ Mouth/Jaw Pain/orbital pain

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Be Suspicious!!!

Ask your questions One confirming symptom Normal or suggestive ocular examination

› GP or Ophthalmologist urgently Request exclusion of GCA› Yes you will be wrong more often than

not. The price of vision is eternal vigilance

Page 26: Neuro-ophthalmology - A cautionary tale

Question 1

In AION caused by GCA the time course to

2nd eye blindness is usually

a. Hoursb. Days c. Weeksd. can be any of above

Page 27: Neuro-ophthalmology - A cautionary tale

Question 2

A new diffuse headache in the elderly is

a. unlikely to be GCA due to poor localization

b. Requires urgent clinical assessmentc. Can be referred for GP assessment in

a few days.d. probably migraine 

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Question 3

Why is aggressive investigation andtreatment required in possible GCA

a. to prevent haemorrhagic strokeb. to prevent permanent bilateral

blindnessc. to avoid steroid complicationsd. to reduce unnecessary osteoporosis