2010-4-25

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    *i"ure 3+ Section from endo myometrium shows squamous

    meta!lasia with hi"h "rade dys!lasia 4'% E 5 6778

    *i"ure 9+ Section shows foci of microinvasion 4' % E 5

    2778

    *i"ure 6+ Section shows invasive squamous cell carcinoma

    of endometrium invadin" the myometrium 4' % E 5 6778

    iscussion+

    Feller in .0>5 first coined the term icthyosis teri in (hich the

    entire srface of endometrim is replaced ;y stratified s%am:os epithelim follo(ing iatrogenically introdced s;stances

    like formalin or iodine#.

    !t sally occr secondary to chronic inflammation, irritation,

    foreign ;odies or follo(ing iatrogenically introdced s;:

    stances in to the terine ca*ity# According to some athors

    icthyosis lack malignant potential#Ho(e*er, dysplastic & ana:plastic changes ha*e ;een reported, (ith fe( e)ceptional case

    reports descri;ing the occrrence of primary $CC:' in the

    ;ackgrond of icthyosis teri# 8,2?ill date only 92 cases of

    $CC:' ha*e ;een reported in the literatre#5Among ..> cases

    of terine corps tmor, oodman fond only si) cases of

    $CC:'#9Varios stdies ha*e pt forth t(o plasi;le e)plana:

    tions for the occrrence of $CC:'# 24>5>:>9-#

    2. Faino RJ# Metaplasia# !n !nterpretation of endo:

    metrial ;iopsies and crettings# 'dited ;y4 $il*er:

    ;erg $# Philadelphia4 ippincott:Ra*en/ .00942.:

    9.#

    3. Heckeroth V, Fiegler H# !chthyosis teri# Case re:

    port on a rate clinical entity# e;rtshilfe raen:

    heilkd# .0>9/2942>:20#

    4. anchan M, +rmila M, $ride*i V, Ra7kmar ?#

    Does ichthyosis teri ha*e malignant potentialI 4

    A case report of s%amos cell carcinoma of endo:

    metrim associated (ith e)tensi*e ichthyosis teri#Diagnostic Pathology# -->/842#

    5. Bagga P, Jas(al ?$, Datta +, Maha7an @C#

    Primary endometrial s%amos cell carcinoma (ith

    e)tensi*e s%amos metaplasia and dysplasia# Indi-an J Pathol Microbiol. --> /5.49:9>#

    6. oodman A, Fker;erg R, Rice =, ller A,ong RH, $clly R'# $%amos cell carcinoma of

    endometrim4 A report of eight cases and a re*ie(

    of the literatre# Gynecol Oncol. .009/9.452:9-

    7. ennedy A$, Demars R, lannegan M, Varia

    MA# Primary s%amos cell carcinoma of the endo:

    metrim4 a first report of ad7*ant chemoradiation#

    Gynecol Oncol..005/504..:.8#