lung cancer: traditional chinese€¦ · 遺傳風險 —...

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1/10 頁,2014 麥克米倫資料頁:肺癌 肺癌 本份資料主要介紹有關肺癌診斷與治療的資訊。 我們還有以您的語言編寫的有關這些治療的資料頁:化療、放療、手術治療,以及癌 症治療的副作用,您可以做什麼來幫助自己,申請福利救濟和臨終關懷。 我們希望本資料可解答您的問題。如果您還有其他問題,可以詢問您正在其中接 受治療的醫院裡的醫生及護士。 如果您想用自己的語言跟我們的癌症援助專員討論此資料,我們有專為非英語人士 安排的口譯員。週一至週五上午 9 時至晚上 8 時,您可以免費致電英國麥克米倫癌 症援助熱線 (Macmillan Support Line)0808 808 00 00。如果您有聽力方面的困難, 可使用我們的文本電話 0808 808 0121 或文字中轉。您還可以造訪我們的網站 macmillan.org.uk本資料主要介紹: 什麼是癌症? 肺部 肺癌的種類 原因和風險因素 症狀 如何診斷肺癌? 分期 治療 臨床試驗 控制症狀 後續復診 您的感覺 以您的語言編寫的更多資訊 什麼是癌症? 人體的器官和組織由稱為細胞的基本單位組成。癌症是這些細胞的一種病變。 人體各個部位的細胞可能不同,但大多數都是以相同的方式自我修復和複製。正常情 況下,細胞以有序的方式分裂。但是,如果這個過程失控,細胞便會不斷進行分裂, 形成一個被稱為腫瘤的腫塊。 Lung cancer: Traditional Chinese

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Page 1: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 1/10 頁,2014 麥克米倫資料頁:肺癌

肺癌

本份資料主要介紹有關肺癌診斷與治療的資訊。

我們還有以您的語言編寫的有關這些治療的資料頁:化療、放療、手術治療,以及癌

症治療的副作用,您可以做什麼來幫助自己,申請福利救濟和臨終關懷。

我們希望本資料可解答您的問題。如果您還有其他問題,可以詢問您正在其中接

受治療的醫院裡的醫生及護士。

如果您想用自己的語言跟我們的癌症援助專員討論此資料,我們有專為非英語人士

安排的口譯員。週一至週五上午 9 時至晚上 8 時,您可以免費致電英國麥克米倫癌

症援助熱線 (Macmillan Support Line):0808 808 00 00。如果您有聽力方面的困難,

可使用我們的文本電話 0808 808 0121 或文字中轉。您還可以造訪我們的網站

macmillan.org.uk。

本資料主要介紹:

什麼是癌症?

肺部

肺癌的種類

原因和風險因素

症狀

如何診斷肺癌?

分期

治療

臨床試驗

控制症狀

後續復診

您的感覺

以您的語言編寫的更多資訊

什麼是癌症?

人體的器官和組織由稱為細胞的基本單位組成。癌症是這些細胞的一種病變。

人體各個部位的細胞可能不同,但大多數都是以相同的方式自我修復和複製。正常情

況下,細胞以有序的方式分裂。但是,如果這個過程失控,細胞便會不斷進行分裂,

形成一個被稱為腫瘤的腫塊。

Lung cancer: Traditional Chinese

Page 2: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 2/10 頁,2014 麥克米倫資料頁:肺癌

並非所有腫瘤都是癌症。醫生可以透過從腫瘤上切下一小片組織或細胞樣本,判斷是

否屬於癌症。這稱為活組織檢查。醫生在顯微鏡下檢測樣本,查找癌細胞。

如果是良性(非癌性)腫瘤,細胞可能會生長,但不會擴散到身體的其他部位。通常,

只有當它壓迫附近的器官時,才會造成問題。

如果是惡性(癌性)腫瘤,細胞會擴散到附近的組織中。有時,癌細胞會從腫瘤首先

出現的地方(初始位置)擴散到身體的其他部位。它們可以透過血液或淋巴系統傳播。

淋巴系統能幫助我們免受感染和疾病的侵襲。它由叫做淋巴管的細小管道組成。它們

在身體各個部分連接到豆子形狀的淋巴結(淋巴腺)群上。

當細胞到達身體另一部位時,它們開始生長,然後形成另一個腫瘤。這稱為繼發性或

轉移性癌。

肺部

我們的胸腔有兩個幫助我們呼吸的肺。右邊的肺分成三部份(稱為肺葉),而左肺分

成兩部份。

肺部

當我們吸氣時,空氣從鼻子或嘴巴穿過氣管。這股空氣在兩支管道分開,每支通往不

同的肺。這兩支正是右支氣管和左支氣管。然後,空氣又會分開到更細的氣管,名為

細支氣管。細支氣管的末端是數以百萬計的細小氣囊,名為肺泡。

肺癌的種類

氣管

細支氣管

右支氣管 左支氣管

肺泡

Page 3: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 3/10 頁,2014 麥克米倫資料頁:肺癌

肺癌主要分為兩種:

非小細胞肺癌(NSCLC)

小細胞肺癌(SCLC)

大約 15%的肺癌(少於五分之一)是小細胞肺癌,其餘的是非小細胞肺癌。

原因和風險因素

吸煙 —大多數肺癌是由吸煙引起的。吸煙吸得越多,您就越有可能患上肺癌。年輕時

就開始吸煙的人也屬於高危人群。抽旱煙、雪茄或大麻也會增加患肺癌的風險。

不吸煙或過去有吸煙的人群也會患肺癌。大約 10%至 15%的肺癌患者從不吸煙。

其他的風險因素包括:

年齡 — 80%的肺癌病例是在 60 歲以上的人群中診斷出來的。

接觸石棉

接觸氡氣

遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。

肺癌沒有傳染性,所以並不會傳染給其他人。

症狀

肺癌的症狀包括:

持續三個星期或更久的咳嗽

長期咳嗽發生病變

胸腔感染不見好轉

呼吸困難和喘息加劇

痰中帶血

聲音沙啞

咳嗽時隱隱作痛或劇痛難耐

食欲不振或體重下降

吞咽困難

過度疲勞和嗜睡

如果您出現其中任何一種症狀,且持續時間超過三個星期,請務必儘快就醫。所有這

些症狀均可能由癌症以外的其他疾病引起。

如何診斷肺癌?

Page 4: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 4/10 頁,2014 麥克米倫資料頁:肺癌

您的家庭醫生 (GP) 將為您作檢查並安排某些檢查項目。如果您的家庭醫生認為您的症

狀可能是由肺癌引起,他們會立即為您安排胸部 X 光檢查。根據檢查結果,您可能要

轉診至醫院,接受專科醫生的建議和治療。

在醫院

專科醫生會在檢查前詢問您的整體健康狀況和您之前存在的健康問題。若您之前不存

在相關的健康問題,您將要進行一次胸部 X 光檢查。

您可能需要進行一項或多項檢查。如下:

支氣管鏡檢查 — 醫生或護士將檢查肺部氣管的內側,並採集細胞樣本。在任何檢查

之前的幾個小時內,您都不能進食或飲水。醫生首先會給您進行局部麻醉,接著給您

注射鎮靜劑,然後把一條軟管插入您的鼻子或嘴巴,直至您的肺部。該檢查大約持續

20 分鐘,數小時後,您就可以回家了。

CT(計算機 X 線斷層攝影機)掃描 — CT 掃描採用一系列 X 線,以構建人體內部的三

維模型。掃描過程將持續 10-30 分鐘,不會引起疼痛。這會產生少量輻射。這對您造

成傷害的可能性非常小,也不會傷害您所接觸的人。掃描前至少 4 個小時您不能進食

或飲水。

醫生可能會讓您喝下或給您注射一些顯影劑,以便能夠更清楚地看到某些部位。這可

能讓您在幾分鐘內感到很熱。您需要事先告知醫生您是否對碘過敏或患有氣喘,這很

重要,因為您可能會對注射產生更嚴重的反應。

PET-CT 掃描 — 這是 CT 掃描和 PET(正電子發射計算機斷層掃描)掃描的結合。PET-

CT 掃描能更詳細地獲知癌症的嚴重程度,並確定癌症是否已經擴散到肺部以外。

肺活檢 — 這一檢查通常在 CT 掃描期間於 X 光室內進行。將對該部位進行局部麻醉。

醫生會將一根細針紮進您的皮膚並進入肺部時,此時您需要屏住呼吸。整個過程中會

採用 X 光照射以確保細針的位置正確。醫生會採集細胞樣本,並在顯微鏡下觀察。肺

活檢時您可能會感覺不舒服,但這只需要幾分鐘。做完活檢幾小時之後,您便可以回

家。

細針吸取 — 醫生或護士會使用一根細針從您脖子上的淋巴結抽取細胞樣本。

因為在肺活檢之後,您身體內部覆蓋肺部的各組織膜間有極小可能會存在空氣。這被

稱為氣胸。症狀包括胸部劇痛、呼吸困難及胸部收緊。若您出現任何這些症狀,請告

訴您的護士。

更多檢查

如果確診為肺癌,則您可能需要做其他的一些檢查。這些檢查可以為您的手術作準備

或者幫助了解更多關於癌症的情況。這些檢查包括:

Page 5: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 5/10 頁,2014 麥克米倫資料頁:肺癌

縱隔鏡檢查

支氣管內超聲波掃描(EBUS)

超聲內鏡檢查(EUS)

MRI(磁共振成像)掃描

腹部超聲波掃描

同位素骨掃描

肺功能檢查

您的醫生或護士會說明您將進行哪些檢查,以及接下來會發生什麼。

等待化驗結果時,您可能會感到焦慮。向親屬或朋友傾訴您的擔憂可能會有所幫助。

您也可以撥打 0808 808 00 00,用您的母語與我們的癌症援助專員交談。

分期

了解您癌症的所處階段有助於醫生為您制訂正確的治療方案。

肺癌分為四個階段:

1 期癌症範圍小,僅限於肺部。

2 期或 3 期癌症已擴散到肺部週圍。

4 期癌症已經擴散到身體其他部位。

還有另一針對小細胞肺癌的階段體系,即分為自限性疾病和廣泛性疾病。若您的醫生

使用該體系,他會向您解釋其情況。

為了安全起見,通常視為小細胞肺癌已擴散來對其進行治療。

治療

確定最佳治療方法並非易事。您的醫生需要考慮很多因素。最重要的幾點包括:

您的總體健康狀況

癌症的分期

治療可能的好處

治療可能的副作用

您對可能出現的副作用的看法

與您的醫生討論治療方法非常重要,這有助於讓您明白它意味著什麼。最好是有既會

講您的語言又會講英語的人隨行。如果您需要,可以為您安排口譯員。但是如果需要

口譯員到場,應提前告知醫院。

專科護士會跟您討論治療方案。他們能幫助解答您在約診期間遇到的任何問題。

Page 6: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 6/10 頁,2014 麥克米倫資料頁:肺癌

您會被要求簽署一份同意書,表明您了解並同意進行治療。只有同意後,才會對您進

行治療。

手術治療

手術治療通常用於消除癌症。它可以用於移除發病範圍小且尚未擴散的非小細胞肺癌。

手術治療很少用於治療小細胞肺癌患者。

針對肺癌的三種主要的手術治療是:

肺葉切除術 — 切除肺葉

肺切除術 — 切除整個肺

肺楔形切除術 — 切除肺的一小部分

手術類型取決於腫瘤的大小和位置。

人們往往擔心他們的肺切除之後會無法正常呼吸。但是,您可以用一個肺正常呼吸。

如果您在手術前就已經呼吸困難,手術後仍可能繼續存在這一症狀。

關於手術計劃以及手術後會出現的情況,我們有更多以您的語言編寫的資訊。

化療

化療指使用抗癌(具有細胞毒性)藥物來破壞癌細胞。藥物會在血液中傳輸,可到達

身體的任何部位。

化療是治療小細胞肺癌的主要方法。它有助於改善呼吸困難、咳嗽、咳血和胸痛等症

狀。

對於非小細胞肺癌,化療有時候用於手術後降低癌症復發的風險。它還能在手術前縮

小腫瘤,或者若手術不可行,能減緩相關症狀。

關於化療的進行方式,以及它的一些副作用,我們有更多以您的語言編寫的資訊。

放療

放療法是指使用儀器從身體外部發射高能射線來破壞癌細胞,對正常細胞的損害程度

則維持在最低水準。

針對小細胞肺癌的放療放療有時用於侷限性小細胞肺癌。如果癌症在化療後已經大幅

好轉或消失,您可以在化療後進行放療(輔助性放療)。

有時候您會同時進行放療和化療。這被稱為化—放療。這兩種治療有助於防止小細胞

肺癌復發,而且有助於完全消除癌症的各種症狀。化療和放療同時進行會使這兩種治

療的副作用加劇。您的醫生或護士能向您提供更多關於化—放療的資訊。

Page 7: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

第 7/10 頁,2014 麥克米倫資料頁:肺癌

小細胞肺癌有時候能擴散至大腦。您可以針對頭部採用一種名為腦部預放性放射治療

的放療方法,以降低這一風險。化療非常成功或者已經做手術移除腫瘤的小細胞肺癌

患者可能需要做這種放療。

針對非小細胞肺癌的放療您可能會採用能治癒非小細胞肺癌的放療(稱為根治性放

療)。這可以代替手術治療。做根治性放療有不同的方式,您的醫生會向您解說您的

治療方案。

如果腫瘤壓迫了某根氣管,您可能需要進行名為支氣管內放療或近距離放療的內部放

射治療。使用支氣管鏡將固定放射源放置在靠近腫瘤的地方,這一過程將持續數分鐘。

然後將其移開。該治療可以重複兩次或三次。這種放療直接針對腫瘤,因此健康的組

織將不會受到太大的影響。這意味著副作用極小。

姑息性放療可能被用於控制症狀。治療次數會更少,而且通常副作用也更小。

外部放射治療並不會讓您的身體也具有放射性,您在治療之後與他人(包括兒童)在

一起也很安全。

關於放射治療的計劃和進行方式,以及它可能會對您產生的一些副作用,我們有更多

以您的語言編寫的資訊。

針對非小細胞肺癌的靶向治療

靶向治療識別癌細胞和正常細胞,並能夠阻止癌細胞生長。如果您需要採用這些療法,

醫生或護士會向您進行相關介紹。

針對非小細胞肺癌的射頻消融治療

這種治療使用熱量來破壞癌細胞。它僅適用於非小細胞肺癌早期的患者,且以其他治

療不適用於該患者為前提。

醫生會在治療前先給您進行局部麻醉,並注射鎮靜劑。在某些情況下,會進行全身麻

醉。醫生將在肺腫瘤裡紮一根針。這一過程通常會使用 CT 掃描儀確保細針的位置正

確。然後無線電波會透過針傳導至腫瘤,從而加熱和破壞癌細胞。

這種治療的副作用很小,儘管術後患者普遍會有一些疼痛或不適以及疲勞感。患者通

常需要在醫院過夜。

光動力療法(PDT)

光動力療法(PDT)使用鐳射或其他光源,結合光敏感藥物(有時被稱為感光媒介)

來破壞癌細胞。

在肺癌的早期階段,PDT 有時會被用於癌症僅在某條主氣管管壁生長(支氣管癌)。

光敏感藥物以液體狀進入靜脈。一旦藥物被癌細胞吸收,鐳射便藉助支氣管鏡直達腫

瘤。

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PDT 會讓您在幾天乃至幾個月對光敏感,這取決於使用的感光藥物。這段時間您需要

避免強光照射。其他副作用包括腫脹、發炎、呼吸困難和咳嗽。

控制肺癌的症狀

在您發病期間,有時候會出現新的症狀,比如呼吸困難或咳嗽。這可能是由癌症引起

的,但也有可能是其他誘因造成的。若您出現任何新症狀,請立即通知您的醫生,以

便接受治療。

呼吸困難 —會是一種難對付的痛苦症狀。有些治療和鍛鍊方法能有助於減緩或控制您

的呼吸困難,還有其他一些活動有助於舒緩您的呼吸困難。這包括各種藥物、輔佐性

治療、呼吸及放鬆技巧。

咳嗽 — 大約 80%的肺癌患者都會咳嗽,而有些治療手段有助於減緩這種症狀。這包括

外部外照射放療、姑息性化療或藥物治療。

胸膜積液 — 肺癌偶爾會在胸膜腔內引起積液現象(胸膜積液)。醫生通常會把一根針

(插管)插入該部位以排出裡面的液體。針與一根管相連,液體會繼而流入一個引流

袋或引流瓶。有時候還可以將兩層胸膜重新粘合在一起。

疼痛 — 一些肺癌患者感到疼痛。通常用止痛藥來控制疼痛或使用其他控制疼痛的方法。

若癌症已擴散至骨骼,您也會感到疼痛。二磷酸鹽等多種藥物有助於舒緩疼痛。醫生

可能會建議您做短療程的放療。

臨床試驗

為了找尋新的更好的癌症療法,已經開展了一些癌症研究試驗。在病人身上進行的試

驗叫做臨床試驗。現在很多醫院都參與了這樣的試驗。請向您的醫生了解目前的肺癌

研究情況。

後續復診

醫生或專科護士可能會讓您做一些常規檢查和 X 光檢查。這是探討您可能存在的任何

問題的好時機。若您在約診期間發現任何新症狀,請儘快告知您的醫生或護士。

您的感覺

當您被告知患有癌症時,會感到不知所措,出現很多不同的情緒。包括生氣、憤怒、

愧疚、焦慮和害怕。這些都是正常的反應,很多人在接受身患癌症這一事實的過程中

都會有這樣的經歷。感覺沒有對錯之分。您會以自己的方式來面對。

以您的語言編寫的更多資訊

乳腺癌資料頁

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化療資料頁

申請福利救濟資料頁

大腸癌資料頁

前列腺癌資料頁

放療資料頁

關於癌症治療副作用的資料頁

手術治療資料頁

關於您可以做什麼來幫助自己的資料頁

本資料由麥克米倫癌症援助機構的癌症資訊編制團隊撰寫、修訂和編輯。本資料經我

們的醫學編輯資深臨床腫瘤學家 Tim Iveson 博士審核。

特此感謝麥克米倫肺科臨床專科護士 Helen Sparkes;麥克米倫肺癌臨床專科護士

Lindsey Fitzpatrick;麥克米倫癌症護士長 Dorinda Palmer;麥克米倫肺科臨床專科護士

Sharron Newbold;以及所有審閱了此版本的受癌症影響的人士。

在編寫此資料頁的過程中,我們使用了來源可信的資訊。包括:

Crinò L 等。早期和局部晚期(非轉移性)非小細胞肺癌:覆蓋診斷、治療及病

情跟蹤的 ESMO 臨床實踐指南 (Early stage and locally advanced (non-metastatic) non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment

and follow-up)。歐洲醫學腫瘤學會 (European Society for Medical Oncology

(ESMO)),2010 年。

D’Addario等。轉移性非小細胞肺癌:覆蓋診斷、治療及病情跟蹤的 ESMO 臨床

實踐指南 (Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines

for diagnosis, treatment and follow-up)。歐洲醫學腫瘤學會 (European Society for

Medical Oncology (ESMO)),2010 年。

肺癌:肺癌的診斷和治療 (Lung Cancer: The Diagnosis and Treatment of Lung

Cancer)。英國國家健康與臨床卓越研究所 (National Institute for Health and Care

Excellence (NICE)),2011 年 2 月。

我們盡最大努力確保我們提供的資訊準確無誤,但其並不能反映最新的醫學研究情況,

因為這是不斷變化的。如果您擔心您的健康狀況,則應諮詢您的醫生。麥克米倫對由

於此資訊或協力廠商資訊(如我們所連結到的網站上的資訊)的任何不準確所造成的

任何損失或損害不承擔任何責任。

© 麥克米倫癌症援助機構 2014 年註冊慈善機構,註冊地為英格蘭和威爾士 (261017)、

蘇格蘭 (SC039907) 及英屬馬恩島 (604)。註冊辦事處位於 89 Albert Embankment,

London, SE1 7UQ。

MAC15137_Traditional Chinese

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Page 1 of 10 Macmillan fact sheet 2014: Lung cancer

Lung cancer: English

Lung cancer This fact sheet is about how lung cancer is diagnosed and treated.

We also have fact sheets in your language about chemotherapy, radiotherapy, surgery, side effects of cancer treatment, what you can do to help yourself, claiming benefits and end of life.

We hope this fact sheet answers your questions. If you have any more questions, you can ask your doctor or nurse at the hospital where you are having your treatment.

If you would like to talk to our cancer support specialists about this information in your language, we have interpreters for non-English speakers. You can call the Macmillan Support Line free on 0808 808 00 00, Monday–Friday, 9am–8pm. If you have problems hearing you can use textphone 0808 808 0121, or Text Relay. Or you can go to our website macmillan.org.uk

This fact sheet is about:

• What is cancer?

• The lungs

• Types of lung cancer

• Causes and risk factors

• Symptoms

• How is lung cancer diagnosed?

• Staging

• Treatment

• Clinical trials

• Controlling symptoms

• Follow up

• Your feelings

• More information in your language

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Page 2 of 10 Macmillan fact sheet 2014: Lung cancer

What is cancer?

The organs and tissues of the body are made up of tiny building blocks called cells. Cancer is a disease of these cells.

Cells in each part of the body are different but most mend and reproduce themselves in the same way. Normally, cells divide in an orderly way. But if the process gets out of control, the cells carry on dividing and develop into a lump called a tumour.

Not all tumours are cancer. Doctors can tell if a tumour is cancer by removing a small sample of tissue or cells from it. This is called a biopsy. The doctors examine the sample under a microscope to look for cancer cells.

In a benign (non-cancerous) tumour, the cells may grow but cannot spread anywhere else in the body. It usually only causes problems if it puts pressure on nearby organs.

In a malignant (cancerous) tumour, the cells grow into nearby tissue. Sometimes, cancer cells spread from where the cancer first started (the primary site) to other parts of the body. They can travel through the blood or lymphatic system.

The lymphatic system helps to protect us from infection and disease. It’s made up of fine tubes called lymphatic vessels. These connect to groups of bean-shaped lymph nodes (glands) all over the body.

When the cells reach another part of the body they begin to grow and form another tumour. This is called secondary cancer or a metastasis.

The lungs

We have two lungs in our chest that help us to breathe in and out. The right lung has three sections (called lobes) and the left lung has two.

Left bronchus

Alveoli

Windpipe(trachea)

Right bronchus

Bronchioles

The lungs

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Page 3 of 10 Macmillan fact sheet 2014: Lung cancer

When we breathe in, air passes from our nose or mouth through the windpipe (trachea). This divides into two tubes, one going to each lung. These are known as the right and left bronchus. They divide into smaller tubes called bronchioles. At the end of the bronchioles are millions of tiny air sacs called alveoli.

Types of lung cancer

There are two main types of lung cancer:

• non-small cell lung cancer (NSCLC)

• small cell lung cancer (SCLC)

About 15% of lung cancers (less than 1 in 5) are small cell lung cancer; the rest are non-small cell lung cancer.

Causes and risk factors

Smoking – Most lung cancers are caused by people smoking cigarettes. The more you smoke, the more likely you are to get lung cancer. People who start smoking at a young age are also at more risk. Smoking pipes, cigars or cannabis can also increase your risk of getting lung cancer.

People who don’t smoke or used to smoke can also get lung cancer. About 10–15% of people who get lung cancer have never smoked.

Other risk factors include:

• Age – 80% of lung cancers are diagnosed in people over 60.

• Exposure to asbestos• Exposure to radon gas

• Genetic risk – If a close relative of yours has had lung cancer you may be at an increased risk.

Lung cancer is not infectious and can’t be passed on to other people.

Symptoms

The symptoms of lung cancer include:

• a cough that lasts three weeks or more

• a change in a long-lasting cough

• a chest infection that doesn’t get better

• increased breathlessness and wheezing

• coughing up blood in your sputum (phlegm)

• a hoarse voice

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Page 4 of 10 Macmillan fact sheet 2014: Lung cancer

• a dull ache or sharp pain when you cough

• loss of appetite or weight loss

• difficulty swallowing

• excessive tiredness (fatigue) and lethargy.

If you have any of these symptoms for more than three weeks, it‘s important to see your GP. All of these symptoms can be caused by illnesses other than cancer.

How is lung cancer diagnosed?

Your GP will examine you and arrange some tests. If your GP thinks your symptoms could be lung cancer, they will send you for an urgent chest x-ray. Depending on the result, you may then be referred to a hospital for specialist advice and treatment.

At the hospital

The specialist will ask you about your general health and any previous medical problems before examining you. If you haven’t already had one, you will have a chest x-ray.

You may have one or more of the tests below.

Bronchoscopy – a doctor or nurse will examine the insides of the lung airways and may take samples of the cells. Before the test, you cannot eat or drink anything for a few hours. You will be given a local anaesthetic and sedation before a thin, flexible tube is passed up your nose or mouth and into your lungs. The test takes about 20 minutes and you may go home after a few hours.

CT (computerised tomography) scan – A CT scan takes a series of x-rays, which builds up a 3D picture of the inside of the body. The scan takes 10-30 minutes and doesn’t hurt. It uses a small amount of radiation. This is very unlikely to harm you and will not harm anyone you come into contact with. You cannot eat or drink for at least 4 hours before the scan.

You may be given a drink or injection of a dye, which allows some areas to be seen more clearly. This can make you feel hot all over for a few minutes. It is important to let your doctor know if you are allergic to iodine or have asthma, because you could have a more serious reaction to the injection.

PET-CT scan – this is a combination of a CT scan and a PET (positron emission tomograph) scan. PET-CT scans give more detailed information about the size of the cancer, and whether it has spread beyond the lungs.

Lung biopsy – This test is usually done in the x-ray department; normally during a CT scan. A local anaesthetic is used to numb the area. You’ll be asked to hold your breath while a thin needle is passed through the skin and into the lung. An x-ray is used throughout the procedure to make sure the needle is in the right place. The doctors will take a sample of cells to examine under a microscope. The biopsy may be uncomfortable, but it only takes a few minutes. You can go home a few hours after the biopsy.

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Page 5 of 10 Macmillan fact sheet 2014: Lung cancer

Fine needle aspiration – a doctor or nurse may use a fine needle to take a sample of cells from the lymph nodes in your neck.

After a lung biopsy there is a small risk you may develop air between the layers that cover the lungs. This is known as a pneumothorax. Symptoms include sharp chest pain, breathlessness and a tight chest. Tell your nurse if you have any of these symptoms.

Further tests

If lung cancer is confirmed then you may have some other tests. These may be used to prepare you for an operation or to find out more about the cancer. They include:

• mediastinoscopy

• endobronchial ultrasound scan (EBUS)

• endoscopic ultrasound (EUS)

• MRI (magnetic resonance imaging) scan

• abdominal ultrasound scan

• isotope bone scan

• lung function tests.

Your doctor or nurse will explain which tests you need and what will happen.

Waiting for test results can be an anxious time for you. It may help to talk about your worries with a relative or friend. You could also speak to one of our cancer support specialists in your language on 0808 808 00 00.

Staging

Knowing the stage of your cancer helps doctors decide the right treatment for you. Lung cancer is divided into four stages:

• Stage 1 The cancer is small and only in the lung

• Stages 2 or 3 The cancer has spread into areas around the lung

• Stage 4 The cancer has spread to other parts of the body.

There is another system of staging for small cell lung cancer that divides it into limited disease and extensive disease. Your doctor will explain this system if they are using it.

To be safe, small cell lung cancers are usually treated as though they have spread.

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Treatment

Deciding on the best treatment isn’t always easy. Your doctor will need to think about a lot of things. The most important of these are:

• your general health

• the stage of the cancer

• the likely benefits of treatment

• the likely side effects of treatment

• your views about the possible side effects.

It’s important to talk about any treatment with your doctor, so that you understand what it means. It’s a good idea to take someone with you who can speak both your language and English. Interpreters may be available if you need one, but try to let the hospital know before if you would like one to be there.

You might have a specialist nurse who can talk to you about treatment. They can also help with any problems you may have in between appointments.

You will be asked to sign a consent form to show that you understand and agree to the treatment. You will not have any treatment unless you have agreed to it.

Surgery

Surgery is often used to remove cancer. It can be used to remove non-small cell lung cancers that are small and haven’t spread. Surgery is rarely used to treat people with small cell lung cancer.

The three main types of surgery for lung cancer are a:

• Lobectomy – removes a lobe of the lung

• Pneumonectomy – removes a whole lung

• Wedge resection – removes a small part of the lung.

The type of operation you have will depend on the size and position of the tumour.

People often worry that they won’t be able to breathe properly if their lung has been removed. But you can breathe normally with one lung. If you had breathing difficulties before the operation, you may still have them after it.

We have more information in your language about how surgery is planned and what to expect after the operation.

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Page 7 of 10 Macmillan fact sheet 2014: Lung cancer

Chemotherapy

Chemotherapy is a treatment that uses anti-cancer (cytotoxic) drugs to destroy cancer cells. The drugs are carried in the blood and can reach anywhere in the body.

Chemotherapy is the main treatment for small cell lung cancer. It can help with symptoms such as breathlessness, coughing, coughing up blood and chest pain.

In non-small cell lung cancer, chemotherapy is sometimes used after surgery to reduce the risk of the cancer coming back. It may also shrink tumours before surgery or relieve symptoms if surgery is not possible.

We have more information in your language about how chemotherapy is given and some of the side effects you may have.

Radiotherapy

Radiotherapy uses a machine to aim high-energy rays from outside the body to destroy the cancer cells, while doing as little harm as possible to normal cells.

Radiotherapy for small cell lung cancer Radiotherapy is sometimes used to treat limited-stage small cell lung cancer. You may have it after chemotherapy (adjuvant radiotherapy) if the cancer has shrunk a lot or disappeared after the chemotherapy.

Sometimes you will have radiotherapy at the same time as chemotherapy. This is called chemoradiation. The two treatments can help to stop small cell lung cancer coming back and may help to completely remove any signs of the cancer. Giving chemotherapy and radiotherapy together can make the side effects of these treatments worse. Your doctor or nurse can give you more information about chemoradiation.

Small cell lung cancer can sometimes spread to the brain. You may be given a type of radiotherapy called prophylactic cranial radiotherapy to your head to reduce the risk of this happening. It may be given to people with small cell lung cancer if chemotherapy has worked very well, or if they have had surgery to remove the tumour.

Radiotherapy for non-small cell lung cancer You may have radiotherapy that aims to cure non-small cell lung cancer (called radical radiotherapy). This can be used instead of surgery. There are different ways of having radical radiotherapy and your doctor will explain your treatment.

If the tumour is blocking one of the airways, you may have internal radiotherapy called endobronchial radiotherapy or brachytherapy. A solid radioactive source is placed close to the tumour for a few minutes using a bronchoscope. It is then removed. This treatment can be repeated two or three times. The radiotherapy goes directly to the tumour so healthy tissue will not be affected much. This means there are few side effects.

Palliative radiotherapy may be used to control symptoms. Fewer treatments are given and they usually have fewer side effects.

External radiotherapy does not make you radioactive and it is safe for you to be with other people, including children, after your treatment.

We have more information in your language about how radiotherapy is planned and given, and some of the side effects you may have.

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Page 8 of 10 Macmillan fact sheet 2014: Lung cancer

Targeted therapies for non-small cell lung cancer

Targeted therapies work on the difference between cancer cells and normal cells and try to stop cancer cells growing. Your doctor or nurse can tell you more about these treatments if you can have them.

Radiofrequency ablation for non-small cell lung cancer

This treatment uses heat to destroy cancer cells. It's only used if you have a very early-stage non-small cell lung cancer and other treatments are not suitable.

You will be given a local anaesthetic and sedation before the treatment. In some cases, general anaesthetic is used instead. Your doctor will place a needle into the lung tumour. This is usually done using a CT scanner to make sure the needle is in the right place. Radiowaves are then passed down the needle into the tumour to heat and destroy the cancer cells.

There are very few side effects with this treatment, although it's common for people to have some pain or discomfort and to feel tired afterwards. You'll usually need to stay in hospital overnight.

Photodynamic therapy (PDT)

Photodynamic therapy (PDT) uses lasers or other light sources, combined with a light-sensitive drug (sometimes called a photosensitising agent) to destroy cancer cells.

PDT can sometimes be used if the cancer is only growing into the wall of one of the main airways (endobronchial cancer) and is at a very early stage.

The light-sensitive drug is given as a liquid into a vein. Once the drug is taken up by the cancer cells, the laser light is directed at the tumour using a bronchoscope.

PDT will make you sensitive to light for a couple of days to a few months, depending on the photosensitising drug used. You will need to avoid bright light during this time. Other side effects include swelling, inflammation, breathlessness and a cough.

Controlling the symptoms of lung cancer

New symptoms can sometimes develop during your illness, such as breathlessness or a cough. These may be caused by the cancer, but they may also have another cause. If you have any new symptoms, tell your doctor straight away so that you can be treated.

Breathlessness – can be a distressing symptom to deal with. There are treatments and exercises that can help to relieve or manage your breathlessness, and things you can do to make living with breathlessness easier. These include different drugs, complementary therapies, and breathing and relaxation techniques.

Cough – About 80% of patients with lung cancer have a cough, and there are treatments to help ease this. These can include external beam radiotherapy, palliative chemotherapy or medications.

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Page 9 of 10 Macmillan fact sheet 2014: Lung cancer

Pleural effusion – Occasionally, cancer in the lung can cause fluid to build up between the layers that cover the lung (pleural effusion). Your doctor can usually drain the fluid by inserting a needle (cannula) into the area. The needle is attached to a tube and the fluid passes into a drainage bag or bottle. Sometimes, it’s possible to seal the two layers of the pleura together again.

Pain – Some people with lung cancer feel pain. This can usually be controlled with painkillers and other methods of pain control. You may also have pain if the cancer has spread to the bones. There are different medications, such as bisphosphonates, that might help with the pain. Your doctor may recommend a short course of radiotherapy.

Clinical trials

Cancer research trials are carried out to try to find new and better treatments for cancer. Trials that are carried out on patients are called clinical trials. Many hospitals now take part in these trials. Speak to your doctor about current lung cancer research.

Follow up

Your doctor or specialist nurse will probably want you to have regular check-ups and x-rays. This is a good time to discuss any problems you may have. If you notice any new symptoms in between these appointments, tell your doctor or nurse as soon as possible.

Your feelings

You may feel overwhelmed when you are told you have cancer and have many different emotions. These can include anger, resentment, guilt, anxiety and fear. These are all normal reactions and are part of the process many people go through in trying to come to terms with their illness. There is no right or wrong way to feel. You’ll cope with things in your own way.

More information in your language

• Breast cancer fact sheet

• Chemotherapy fact sheet

• Claiming benefits fact sheet

• Large bowel cancer fact sheet

• Prostate cancer fact sheet

• Radiotherapy fact sheet

• Side effects of cancer treatment fact sheet

• Surgery fact sheet

• What you can do to help yourself fact sheet

Page 20: Lung cancer: Traditional Chinese€¦ · 遺傳風險 — 如果您的一位近親患有肺癌,則您的患病風險將更高。 肺癌沒有傳染性,所以並不會傳染給其他人。

Page 10 of 10 Macmillan fact sheet 2014: Lung cancer

This fact sheet has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been approved by our medical editor, Dr Tim Iveson, Consultant Clinical Oncologist.

With thanks to: Helen Sparkes, Macmillan Lung Clinical Nurse Specialist; Lindsey Fitzpatrick, Macmillan Lung Cancer Clinical Nurse Specialist; Dorinda Palmer, Macmillan Lead Cancer Nurse; Sharron Newbold, Macmillan Lung Clinical Nurse Specialist; and the people affected by cancer who reviewed this edition.

We have used information from many reliable sources to write this fact sheet. These include:

• Crinò L, et al. Early stage and locally advanced (non-metastatic) non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. European Society for Medical Oncology (ESMO). 2010.

• D’Addario, et al. Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. European Society for Medical Oncology (ESMO). 2010.

• Lung Cancer. The Diagnosis and Treatment of Lung Cancer. National Institute for Health and Care Excellence (NICE). February 2011.

We make every effort to ensure that the information we provide is accurate but it should not be relied upon to

reflect the current state of medical research, which is constantly changing. If you are concerned about your health,

you should consult your doctor. Macmillan cannot accept liability for any loss or damage resulting from any

inaccuracy in this information or third-party information such as information on websites to which we link.

© Macmillan Cancer Support 2014. Registered charity in England and Wales (261017), Scotland (SC039907) and

the Isle of Man (604). Registered office 89 Albert Embankment, London SE1 7UQ.