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P1-6-20-D Fontan循環動物実験モデルによる小児用肺循環補助装置の評価○山田　昭博1、白石　泰之2、三浦　英和2、坪子　侑佑1、平　恭紀1、佐野　恭介1、山岸　正明3、本間　大4、山家　智之2

1東北大学大学院　医工学研究科、2東北大学　加齢医学研究所、3京都府立医科大学　小児心臓血管外科、4トキ・コーポレーションExamination of pediatric pulmonary circulation assist device based on Fontan circulation animal experimental model○AKIHIRO YAMADA1, Yasuyuki Shiraisihi2, Hidekazu Miura2, Yusuke Tsuboko1, Yasunori Taira1, Kyosuke Sano1, Masaaki Yamagishi3, Dai Homma4, Tomoyuki Yambe2

1Graduate School of Biomedical Engineering, Tohoku University, Sendai, JAPAN, 2Institute of Development, Aging and Cancer, Tohoku University, Miyagi, Japan, 3Department of Paediatric Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan, 4Toki Corporation,Tokyo, Japan

Fontan procedure is the final palliative surgical operation in pediatric patients with congenital heart disease. After Fontan procedure, there is non-pulsatile flow in the pulmonary circulation. We have been developing the pulmonary circulation assist device for the Fontan circulation using shape memory alloy fibers. The device structure is mechanically contraction from the outside of the extracardiac conduit. For clinical application of the device, we have been also developing the animal experimental model for in vivo examination of the Fontan circulation assist device. In this study, we examined the hemodynamics change in the device driving the animal experimental model. The animal experimental model was constructed in four adult goats (45.8±15.6 kg). The right heart bypass of inferior vena cava to pulmonary artery was constructed by using extracardiac conduit, and the left ventricular assist device was connected to reduce of left ventricular load. The device could be mounted easily to the conduit in the thoracic cavity. The pulsatile flow could be generated in the pulmonary circulation by the device contraction. We performed the evaluation of the pediatric pulmonary circulatory assist device in the animal experimental model.

P1-6-21-D 直接結合および静電結合による経皮的エネルギー伝送に関する基礎的研究○斎藤　逸郎、村上　遥、阿部　裕輔東京大学大学院医学系研究科医用生体工学Basic study of transcutaneous energy transmission system using direct or capacitive coupling electrode○ITSURO SAITO, HARUKA MURAKAMI, YUSUKE ABEDepartment of Biomedical Engineering, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Transcutaneous energy transmission system (TETS) was studied in order to realize a complete implanted artificial heart. A electromagnetic induction coupling was used in most TETS. Because the living body can be considered as a conductive and a dielectric material, it is possible to drain a high frequency current through direct or capacitive coupling into the body. In this study, We studied possibility of the high frequency current energy transmission through direct of capacitive coupling. A direct or capacitive coupling TETS was developed using two 2 cm square aluminum foils as electrodes of the TETS. For capacitive coupling TETS the electrodes covered with polymethl pentene film. A energy transmission test was performed using a meat as a phantom, a 4 MHz frequency and 500 Ω impedance power supply, a rectifying circuit and resistance load. Transmission electricity decreased to nearly 10% with 500 Ω load, however it remained in 80% with 5 Ω load. A cause of low transmission efficiency seems that the high frequency current passed through not only the resistance load but also the phantom. For improvement of the transmission efficiency, the electrode shape is resigning and the high frequency power supply impedance is adjusting.

P1-6-22-D 高速動画像解析による補助循環時の末梢循環モデル化の試み：血液密度モデルを用いた基礎検討○白石　泰之、佐野　恭介、北野　智哉、三浦　英和、佐々木　一益、山家　智之東北大学　加齢医学研究所Effects of blood volume on non-invasive assessment of peripheral perfusion with ventricular assist devices using a high speed CCD○YASUYUKI SHIRAISHI, Kyosuke Sano, Tomoya Kitano, Hidekazu Miura, Kazumasa Sasaki, Tomoyuki YambeInstitute of Development, Aging and Cancer, Tohoku University, Japan

Rotary blood pumps are commonly employed as circulatory support, which might cause changes in circulation in end organs. The purpose of this study was to develop a noninvasive and contactless system for measurement of peripheral perfusion by using a high-speed camera. A measurement system was designed to derive the amplitude of the green level (AGL). The static test of colour intensity was performed in vitro to verify the blood volume density in the materials. We employed a volume density model, which consisted of a polymer sponge under the different absorption condition using fresh goat blood. The sponge with blood was sandwiched between acrylic plates and the gap between them was varied by the linear table so that the density could be evaluated. The intensity of CCD data on the top flat plate was captured and analysed. As a result, the relationship between the density of blood and the CCD intensity could be evaluated under the LED lighting conditions. Therefore, it was indicated that the AGL could be reflected by the blood volume and the system by using a high-speed camera might be useful for measuring patients’ perfusion under the pump support condition.

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