cgubbs.cgu.edu.tw (O)Ffical (M) 醫學院 [ 系所 ] Parasitology

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校院資訊教學講義分享醫學院基礎醫學研究所寄生蟲學鄧致剛教學網頁：蟲網教學網頁：蟲網

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寄生蟲學科寄生蟲學科醫學大樓 0707王姮臨

鄧致剛 醫學大樓 0706

陳維鈞 醫學大樓 0763

王蓮成 醫學大樓 0710

NEMATODA (Roundworms) 線 蟲

TREMATODA (Flukes) 吸 蟲

CESTODA (Tapeworms) 絛 蟲

Nemathelminthes 線形蠕蟲Nemathelminthes 線形蠕蟲Platyhelminthes 扁平蠕蟲Platyhelminthes 扁平蠕蟲

Human Parasitic Helminthes人 體 寄 生 蠕 蟲

Human Parasitic Helminthes人 體 寄 生 蠕 蟲

N1

NEMATODESNEMATODES 線蟲Blood and Tissue Nematode Blood and Tissue Nematode (( 血液及組織線蟲血液及組織線蟲 ))Blood and Tissue Nematode Blood and Tissue Nematode (( 血液及組織線蟲血液及組織線蟲 ))

Intestinal NematodesIntestinal Nematodes (( 腸道線蟲腸道線蟲 ))Intestinal NematodesIntestinal Nematodes (( 腸道線蟲腸道線蟲 ))Ascaris lumbricoides Ascaris lumbricoides (( 蛔蟲蛔蟲 ))Enterobius vermicularis Enterobius vermicularis (( 蟯蟲蟯蟲 ))Trichuris trichiura Trichuris trichiura (( 鞭蟲鞭蟲 ))Hookworms (Hookworms ( 鉤蟲鉤蟲 )) Necator americanus Necator americanus (( 美洲鉤蟲美洲鉤蟲 )) Ancylostoma duodenale Ancylostoma duodenale (( 十二指腸鉤蟲十二指腸鉤蟲 )) Ancylostoma caninum Ancylostoma caninum (( 犬鉤蟲犬鉤蟲 ))Strongyloides stercoralis Strongyloides stercoralis (( 糞小桿線蟲糞小桿線蟲 ))Capillaria philippinensis Capillaria philippinensis (( 菲律賓毛線蟲菲律賓毛線蟲 ))Trichostrongylus spp. Trichostrongylus spp. (( 毛圓線蟲毛圓線蟲 ))

N1

Importance of Importance of Inestinal NematodiasisInestinal Nematodiasis

Ascaris lumbricoidesAscaris lumbricoides (( 蛔蟲蛔蟲 )) 101008 million 08 million

Hookworms Hookworms (( 鉤蟲鉤蟲 ))

800 million800 million

Trichuris trichiura Trichuris trichiura (( 鞭蟲鞭蟲 ))

900 million900 million

Enterobius vermicularis Enterobius vermicularis (( 蟯蟲蟯蟲 ))

500 million500 millionTotal WorldPopulation

~4500 million

Total WorldPopulation

~4500 million

N1

oviparous 卵生vlarviparous 胎生

Female + male wormsFemale +

male worms

moulting 蛻皮L2

moulting 蛻皮L2

Unfertilised eggs末受精卵

Unfertilised eggs末受精卵

Fertilised eggs受精卵

Fertilised eggs受精卵

Embryonated eggs胚卵

1st stage larva (L1)

Embryonated eggs胚卵

1st stage larva (L1)Hatch (L1)

Hatch (L1)

Adult wormsAdult worms

Infective感梁期

L3 L3

L4 L4

Infective感梁期

Nematode Life Cycle Nematode Life Cycle 線蟲生活週期線蟲生活週期Direct 直接 and Indirect 間接 life cycles

N4

Life Span of some common Life Span of some common intestinal Nematodesintestinal Nematodes

3 months1 year1~3 years4~20 years5~7 years> 30 years

Life SpanLife SpanLife SpanLife SpanParasiteParasiteParasiteParasiteEnterobius vermiculars 蟯蟲Ascaris lumbricoides 蛔蟲Trichuris trichiura 鞭蟲Necator americanus 美洲鉤蟲Ancylostoma duodenale 十二指腸鉤蟲Strongyloides stercoralis 糞小桿線蟲

N4

Drugs for Intestinal Nematode InfectionsDrugs for Intestinal Nematode Infections

A.l. T.t. E.v. N.a. A.d. S.s

High anthelminthic activityModerate anthelminthic activity

Mebendazole

PyrantelLevamisole

Thiabendazole

Piperazine

Tetrachloroethylene

Bephenium

Albendazole

N5