dermatoterapi satya.ppt

8/20/2019 dermatoterapi satya.ppt

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PRINSIP TERAPIDERMATOLOGI


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CARA PENGOBATAN

CARA

PENGOBATAN

TOPIKAL

PRIMER SEKUNDER

BEDAH

LISTRIK

LASER

SINAR UV

RADIOTERAPI

SISTEMIK


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Pemilihan Obat Topial

Um!"

Pemilihan a#en $an# tepat

Loa%i &an l!a% t!b!h $an# te"ena

Sta&i!m pen$ait &an 'eni% le%i

Kon%ent"a%i bahan ati( &alam )ehi!l!m

Meto&e aplia%i

Penent!an lama pemaaian


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Kha%iat Obat Topial

Poten%i obat

Kemamp!an penet"a%i


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Penet"a%i obat topial &i !lit

melal!i*

St"at!m o"ne!m

⇓Epi&e"mi%

⇓

papila &e"mi%

⇓ali"an &a"ah


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Ab%o"p%i Obat Topial

St"at!m o"ne!m

Ol!%i

+"e!en%i pemaaian

,!mlah pemaaian

+ato" lain-lain


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TOPIKAL

PEDOMAN

TERAPI

Semain a!t * bahan %emain lemahI( &"$ .et it/ i( .et &"$ it

a0 ba%ah &en#an

ba%ah 1ba%i% ai"2

b0 e"in# &en#an

e"in# 1ba%i% 3al(2


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Obat Topial

Bahan ati( Vehi!l!m


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Vehi!l!m

P"epa"at pemba.a 3at ati( %!at! obat0

Ke#!naan )ehi!l!m non %pe%i(i*40Men&in#inan/ melin&!n#i/ emolien/ ol!%i( &ana%t"in#en

50Vehi!l!m optimal bila %tabil 1imia/ (i%i2 &an ti&a

menonati(an obat060Nonale"#i/ noni"itan/ &apat &ite"ima %e7a"a o%meti&an m!&ah &ipaai


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Vehi!l!m

CAIRAN BEDAK

KOCOK

BEDAK

PASTA

PENDINGINKRIM

SALAP

PASTA

BERLEMAK


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Cai"an


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KOMPRES TERBUKA

8 Pen#!apan &i%!%!l ab%o"b%ie%!&at

8 In&ia%i * !l!% oto" / in(e%i1e"i%ipela%2/ &e"mato%i%ma&i&an%

8 E(e * K!lit e"in#/)a%oon%t"i%i/ !lit &in#in/e"itema be"!"an#

8 Ca"a * a%a

KOMPRES TERTUTUP

8 Va%o&ilata%i

8 In&ia%i * elainan $# &alam1lim(o#"an!loma )ene"i!m2

8 Ca"a * pembal!t tebal 9&it!t!p pla%ti

Cai"an


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Be&a


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Campuran air dan bedak, yang biasanya ditambahdengan gliserin sebagai bahan perekat

Be&a Ko7o


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Bahan lemak atau mirip lemak yang pada suhu kamarknsistensi seperti mentega!

Salap


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Salap


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KRIM

Bahan .ate" 9 oil 9 em!l#ato"

In&ia%i

A!t:S!ba!t

Ko%meti

,eni%

be"amb!t

Lipatan

1.:o2

1o:.2 Men&in#inan

E(e Emolien


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PASTA

PASTA PENDINGIN : LINIMEN PASTA BERLEMAK

Bahan * 7ai"an 9 be&a

9 %alap

In&ia%i * &e"mato%i%

%!b a!t

Konta * &e"mato%i%ma&i&ane%

Bahan * be&a 9 )a%elin

+!n#%i *

- p"oteti( 9 men#e"in#an

- p"ote%i : tabi" %!"$a

In&ia%i * &e"mato%i% $# a#a

ba%ah

Kont"a * &ae"ah be"amb!t: lipatan :

#enital


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Se&iaan hi&"ooloi& ata! hi&"o(ili be"!pa %!%pen%i $an#&ib!at &a"i %en$a.a o"#ani0

;at !nt! membent! #el &ianta"an$a ialah a"bome"/

meti%el!lo%a/ &an t"a#aan0

Gel


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Bahan Ati(

8 Al!min!m a%etat8 Al!mini!m lo"i&a8 A%am a%etat8 A%am ben3oat8 A%am bo"at

8 A%am %ali%ilat8 A%am t"ilo"a%etat8 A%am !n&e%ilenat8 A%am )it A8 Ben3il ben3oa%

8 Ben3oain8 Campho"a8 Anti 'am!" 8 Antibioti

8 Dit"anol8 +o"malin8 +l!o"o!"a7il8 Io&olo"hi&"o%i!inolin

8 Krtiksterid tpikal8 K"otamiton8 Mentol8 Po&opilin8 Seleni!m %!l(i&a

8 S!l(!" 8 Te" 8 Tio%!l(a% nat"i!%8 U"ea


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Khasiat paliati" dan supresii" antiin"lamasi,antialergi, antipruritus, antimittik, #asknstriksi

Ko"tio%te"oi& topial


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Pen##olon#an

Lemah anti in(lama%i/ anti mitoti 1-2

Se&an# anti in(lama%i/ anti mitoti %e&an#

K!at anti in(lama%i/ anti mitoti !at

S#t !at anti in(lama%i/ anti mitoti %#t !at

E(e %ampin# te"'a&i bila*

Pen##!naan lama &an be"lebihan

Pen##!naan poten%i !at ata! %an#at !at ata! %e7a"a ol!%i(

Ge'ala e(e %ampin# at"o(i/ %t"ie at"o(i%e/ telen#ieta%i%/ p!"p!"a/

&e"matiti% ane(o"mi%/ hipe"t"io%i%/ hipopi#menta%i



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TOKSISITAS

Te"#ant!n# obat/ )ehi!l!m/ ol!%i/ loa%i/ ("e!en%i/

&!"a%i/ 'eni% elainan !lit/ on&i%i "enal/ hepa"


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LOKAL

I"ita%i/ ale"#i/ at"o(i/ ome&o#eni/ telean#ieta%i%/

p"!"it!%/ %tin#in#/ &an n$e"i0

p"o%e% pen#e"in#an !lit/ ata! me"!%a lapi%an !litepi&e"mi%0

SISTEMIK

Pen$e"apan pe"!tan 1SSP/ %ho ana(ilati "enal/a"&ia/te"ato#en/ &an a"%ino#en20

Non im!nolo#i &apat te"'a&i pa&a e"a7!nan pepti%i&a0

TOKSISITAS


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,UMLAH OBATAREA L$AS

PER%$KAAN &'(

)*APLIKASI&gram(

+*-ARISeminggu&gram(

.*-ARISeminggu&gram(


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TERAPI SISTEMIK DALAM

DERMATOLOGI8 AN/I 0IR$S dan DAPS1N

8 AN/I 2A%$R

8 AN/I -IS/A%IN

8 AN/I %ALARIA8 K1R/IK1S/ER1ID

8 1BA/ I%$N1S$PRESI3


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MEKANISME KER,A


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Indikasi

U"tia"ia/ ana(ila%i%/ "hiniti% ale"#ia/ on'!n#ti)iti% ale"#ia0

Kntra indikasi Dsis E"ek samping

Ti&a &apat &ibe"ianpa&a ehamilan0

- Dapat &im!lai &a"i &o%i%

"en&ah &an em!&ian

&itin#atan %e7a"abe"tahap0

- Dapat &ibe"ian

ombina%i &a"i 5

antihi%tamin &a"i ela%

$an# be"be&a

- Se&a%i0

- Pen$ait

'ant!n# %epe"ti#an##!an "itme

'ant!n#0

- E(e oline"#i

%epe"ti*

"eten%io !"in/m!l!t e"in#/

&apat

men$ebaban

%t"oe0

Class Agent Dose Sedating CommentsE h l i Di h h d i () )* , h


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Ethanolamine

Ethylenediamin

e

Piperazine

Alkylamine

Phenothiazine

Piperidine

Nonsedating H1

Thioguanidine

Triyli

antidepressant

Diphenhydrami

ne

Clemastine

Tripelennamine

Hydro!yzine

Chlorphenirami

ne

Promethazine

Cyproheptadine

Azelastine

Cetirizine"e#oetirizine

E$astine

%e!o&enadine

"oratadine

Desloratadine

'isolastineCimetidine

()-)*mg +,-h

1-( mg $.i.d

()-)* mg +,-h

1*-)*mg +-/0

)*mg HS

(-, mg +,-h

1(.)mg t.i.d-

+.i.d.0 ()mg HS

,mg +,-h

(mg $.i.d.

1*mg daily or

$.i.d

)mg daily or$.i.d

1*mg daily or

$.i.d

*mg $.i.d. or

*-1/* mg

daily

1*mg daily)mg daily

1*mg daily

** mg +.i.d.

222

2

22

22

2

222

2

-

-

-

--

-

-

-

-

-

22

Physial

urtiarias3

nighttime use

Nighttime use

Cold urtiaria3

nighttime use0

antiserotonin

ati#ity

Not

meta$olized in

li#er

"ong hal&-li&e

"ong hal&-li&e0

notmeta$olized in

li#er

%or skin

diseases3 used

4ith H1 $loker0

also

immunomodula


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Te"api Ko"tio%te"oi& Si%temi

Ko"tio%te"oi& %i%temi e(e im!no%!p"e%an &an anti-in(lama%i

In&ia%i De"mato%i% ale"#ia ata! $an# &ian##ap memp!n$ai

&a%a" ale"#i

P"in%ip pen#obatan tapp o((

E(e %ampin#*

Hipe"%e"e%i a%am lamb!n#

Hipot"o(i

O%teopo"o%i%

Im!nita% men!"!n

Sin&"om 7!%hin#


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dermatoterapi satya.ppt

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