epidemiologi.henny.406138077

8/17/2019 Epidemiologi.henny.406138077

1/27

EPIDEMIOLOGI LANSIA DANPERMASALAHANNYA, EPIDEMIOLOGIALZHEIMER DISEASE, KERUGIAN

DAN BIAYA-BIAYANYA, SERTA TENTANG FUNGSI KOGNITIF DAN

MEMORI

Referat oleh He! Hal"#,$%&'()%**

KEPANITERAAN KLINIK ILMUGERIATRI

PANTI WERDA KRISTEN HANA

PERIODE 7 JULI 2014 S/D 9


2/27

EPIDEMIOLOGI LANSIA DANMASALAHNYA

• La+t "a a.alah ora/ !a/ "te#-"te# 0"olo/"!a #e/ala#"1er0aha-1er0aha tr2tr .a f/"

."2area2a "a!a !a/ .ah la+t3• D"tr"0" "a 1o1la" telah 0er0ah .a

a2a ter 0er0ah, 2area 1era +a/2a 1a+a/ .ala# t"/2at 2e0ra.a 1er0a"2a .ala# a/2a 2e#at"a3

Harr"o453 Pr"6"1le Of Iteral

Me."6"e3 E"/hteeth E."t"o3 TheM6Gra7-H"ll 8o#1a"e9 U"te.


3/27




4/27




5/27

• Se#etara 1e"/2ata hara1a h".1, ."ha"l2a.ar" era/2a"a o"al, e2oo#", 2eehata#a!ara2at, .a "o;a" #e." ata at 1e!a2"t3

• Sat aat e2"tar tah :%:%, +#lah ora/ 0er"a&< ata le0"h ta ." ."a "" ."1er2"ra2a a2a#ele0"h" aa2-aa2 ." 0a7ah "a < tah3

• Se2"tar 1erte/aha a0a. 2e.a 1lh, 2elo#1o2"a ." 0a7ah < tah ha#1"r ')@ +ta?, .a A#er"2a Ser"2at >


6/27




7/27

• Dala# e#1at .e2a.e atara tah:%'% .a :%


8/27




9/27




10/27




11/27

• Se+arah 1era #ortal"ta .a1e"/2ata hara1a h".1 #e+22a0ah7a 1er0a"2a .ala# ta.ar h".1ter#a2 – 1e"/2ata .a 1er0a"2a 1e."."2a – 1e"/2ata /"" – 1er0a"2a 2eehata #a!ara2at – Pe"/2ata 1e#aha#a teta/ teor" 2#a

1e!a2"t – 1e"/2ata 1reta" #e." e1ert" at"0"ot"2 – 1e"/2ata 1e#aha#a fa2tor r""2o t2

1e!a2"t +at/ .a 1ere.ara .arah #e+a."fa2tor3




12/27




13/27




14/27

KESIMPULAN

• Po1la" 1eaa #er1a2a feo#ea /lo0al.e/a "#1l"2a" !a/ 0ear .ala# +a/2a1e.e2 .a 1a+a/ t2 2eehata .a2e0tha 1era7ata +a/2a 1a+a/, .a

#e#a/ t2 2ee+ahteraa e2oo#" .ao"al .ar" e/ara3 a2t .a 2ote2 1eaa0er;ar"a" ." et"a1 7"la!ah ."a .a e/ara-e/ara3 Se+ah #aa 1eel"t"a .a1at#ee#2a ol" !a/ #e/ra/" 6a6at C"2

.a 2o/"t"f ." "a ta a2a #e+a." fa2tor"/"C2a .ala# 0a/a"#aa e/ara-e/ara#e/ata" 1er0aha #e.aar "" 1a.a1o1la" .a #a!ara2at3




15/27

EPIDEMIOLOGI ALZHEIMERDISEASE

• T"+aa The orl. HealthOr/a"at"o 1a.a tah :%%% ."Glo0al Br.e of De#et"a, !a/

#er1a2a aal"" .ar" $* r;e" ."'* e/ara t"/2at 1er2"raa t2.e#e"a 9

– '= 1a.a ora/ 0er"a &%-&@ tah, – (@= 1a.a ora/ 0er"a @%-@< tah3

htt19e#e."6"e3#e.6a1e36o#art"6le''($)'*-o;er;"e7a7:aa0&0:0&aa


16/27

• Pre;ale" .e#e"a 1a.a ora/ "a&< tah .a le0"h ta ." A#er"2aUtara e2"tar &-'%=, .e/a AD .a

1ert"/a .ar" 2a ""3• T"/2at 1re;ale" .e#e"a ."te#2a

#e+a." '',: 1er '3%%% ." atara 8"a0er"a


17/27

• Pre;ale" AD #e"/2at .e/a"a3

• AD !a/ 1al"/ ## 1a.a ora/ ta"a &% tah ata le0"h3

• Be0era1a 0et2 fa#"l"al a7al-a7alAD .a1at #6l 1a.a a7al .e2a.e

2et"/a, teta1" 2a-2a fa#"l"al2ra/ .ar" '%= .ar" 2eelrha AD3

htt19e#e."6"e3#e.6a1e36o#art"6le''($)'*-

o;er;"e7a7:aa0&0:0&aa


18/27

• Sa;;a .22 h0/a atara .e#e"a.a Ctr 1atolo/" AD >#"al!a, er"t"61lae, ."e 1lae, ta/le? le0"h2at 1a.a ora/ "a *< tah

."0a."/2a ora/ "a @< tah3• R""2o le0"h t"//" 1a.a 7a"ta

."0a."/2a 1a.a 1r"a3• Set"a1 1er0e.aa e2al #e6er#"2a

hara1a h".1 1ere#1a le0"h t"//"3• D" atara !a/ hetero"/ot t2 APOE E$

allele r""2o .a 2al" l"1at #e"/2at 1a.a7a"ta >Pa!a#" .22?3




19/27

Ke"#1la

• Pre;ale" AD #e"/2at .e/a"a3 AD !a/ 1al"/ ## 1a.aora/ ta "a &% tah ata le0"h3

R""2o le0"h t"//" .ar" AD 1a.a7a"ta ."0a."/2a 1a.a 1r"a !a/#e6er#"2a hara1a h".1

1ere#1a le0"h t"//"3




20/27

KOGNITIF DAN MEMORI

• Ko/"t"f ter#a2

– #e#or",

– 0ahaa,

– or"eta",

– 1e"la"a,

– #ela22a h0/a "ter1eroal,

– #ela22a t".a2a, .a

– 1e#e6aha #aalah3


21/27

• Ga//a 2o/"t"f /a//a .ala# atata le0"h .ar" !a/ ." ata3

• 8otoh !a/ 2o#1le2 atara erolo/",o0at-o0ata, .a 1"2"atr" .ala# 2o.""#e." ata erolo/" /a//a 2o/"t"f0erh0/a .e/a /e+ala 1er"la23

• T"/a 2elo#1o2 1e!a2"t .el"r"#,.e#e"a, .a a#et"6 ."or.er /e+ala ta#a 9 1era 2o/""

– e1ert" .ala# #e#or", 0ahaa, ata1erhat"a3


22/27

• Pre;ale" /a//a 2o/"t"f ter#a2.e#e"a #e"/2at e+ala 0erta#0ah!a"a – (= "a &Roe, '@)*?3


23/27

• Fa2tor la" !a/ 0er1e/arh terha.a1f/" 2o/"t"f 9

• "a,

•1e."."2a,

• 1e2er+aa .a

• t"//al e."r" >Fre"." et al3, '@@&?3


24/27

• I.oe"a e/ara 2ee#1at ."a !a/#e#"l"2" 1o1la" "la tert"//"3

– ."1er2"ra2a a2a #e+a." 2et"/a tert"//" 1a.a:%:%3

• Fa2tor-fa2tor /a!a h".1 9 t"#la" "tele2tal0er2a"ta .e/a 2o/"t"f, tat o"al .aa2t";"ta C"2 #er2a r""2o t2

Alzheimer’s disease .a .e#e"a ;a2lar3

• A2t";"ta C"2 #e6e/ah 2e#.raf/" 2o/"t"f3


25/27

• A2t";"ta C"2 #e"/2at2a f/"2o/"t"f, ter#a2 #ere2a !a/ telah."."a/o" .e/a /a//a

2o/"t"f r"/a ata Mild CognitiveImpairment >M8I? > Alzheimer's

Association International Conference

>AAI8?, :%':?3


26/27

Ke"#1la

• Ko/"t"f ter#a2 #e#or", 0ahaa,or"eta", 1e"la"a, #ela22ah0/a "ter1eroal, #ela22a

t".a2a, .a 1e#e6aha #aalah3 T"/a2elo#1o2 1e!a2"t !a/ 0erh0/a.e/a 1era f/" 2o/"t"f !a"t.el"r"#, .e#e"a, .a a#et"6."or.er3 Pre;ale" /a//a 2o/"t"f#e"/2at e+ala 0erta#0ah!a "a3


27/27

S#0er

• Sa.o62 B, Sa.o62 A3 Ka1la Sa.o624S!o1" of P!6h"atr!9 Beha;"oralS6"e6e8l""6al P!6h"atr!3 '%th E."t"o3L"11"6ott "ll"a# "l2", :%%*3

• Satoo TB, Roh#ah ASN3 Ga//aGera2 Da F/" Ko/"t"f Pa.a a"taLa+t U"a3 Sra2arta, :%''3

• Ma#"l MS, Afr"7ar.", Mart"" RD3

H0/a Atara T"/2at A2t";"ta F""2.e/a F/" Ko/"t"f 1a.a U"la ."Kelraha at" Ke6a#ata Pa.a/ T"#r3Pa.a/ T"#r, :%'$3

epidemiologi.henny.406138077

Documents