volkow204

Upload: shekar-reddy

Post on 10-Apr-2018

221 views

Category:

Documents


0 download

TRANSCRIPT

  • 8/8/2019 Volkow204

    1/50

    Directors Report to theNational Advisory Council

    on Drug Abuse

    Directors Report to theNational Advisory Council

    on Drug Abuse

    February 12, 2004February 12, 2004

  • 8/8/2019 Volkow204

    2/50

    Recent NIDA StaffAppointments/Changes

    Recent NIDA StaffAppointments/Changes

    Richard A. Millstein, J.D.

    Acting Deputy DirectorNIH John E. Fogarty International Centerfor Advanced Study in the Health Sciences

    Richard A. Millstein, J.D.

    Acting Deputy DirectorNIH John E. Fogarty International Centerfor Advanced Study in the Health Sciences

  • 8/8/2019 Volkow204

    3/50

    Recent NIDA StaffAppointments/Changes

    Recent NIDA StaffAppointments/Changes

    Timothy P. Condon, Ph.D.Deputy Director, NIDA

    Timothy P. Condon, Ph.D.Deputy Director, NIDA

    andand

    Director, OSPCDirector, OSPC

    NIDA

  • 8/8/2019 Volkow204

    4/50

    Directors Report to theNational Advisory Council on Drug Abuse

    Directors Report to theNational Advisory Council on Drug Abuse

    Science HighlightsScience Highlights

    Whats New at NIH?Whats New at NIH?

    Budget UpdateBudget Update

    Recent NIDA ActivitiesRecent NIDA Activities

    FY 2004 and BeyondFY 2004 and Beyond

  • 8/8/2019 Volkow204

    5/50

    Whats New at NIH?Whats New at NIH?

  • 8/8/2019 Volkow204

    6/50

    NIH Central Steering CommitteeNIH Central Steering Committee

    Rotating Members (three year terms):

    Francis Collins Genome Research Institute Richard Hodes Aging Stephen Katz Arthritis Musculoskeletal & Skin Diseases Donald Lindberg National Library of Medicine

    Stephen Straus Complementary & Alternative Medicine Larry Tabak Dental & Craniofacial Research Nora Volkow NIDA

    Rotating Members (three year terms):

    Francis Collins Genome Research Institute Richard Hodes Aging Stephen Katz Arthritis Musculoskeletal & Skin Diseases Donald Lindberg National Library of Medicine

    Stephen Straus Complementary & Alternative Medicine Larry Tabak Dental & Craniofacial Research Nora Volkow NIDA

    Permanent Members (three largest institutes):

    Andrew von Eschenbach National Cancer Institute Barbara Albin National Heart, Lung and Blood Institute Anthony Fauci National Institute of Allergy and Infectious Diseases

    Permanent Members (three largest institutes):

    Andrew von Eschenbach National Cancer Institute Barbara Albin National Heart, Lung and Blood Institute Anthony Fauci National Institute of Allergy and Infectious Diseases

  • 8/8/2019 Volkow204

    7/50

    Enhancing the Vitality of theNational Institutes of Health:

    Organizational Change toMeet New Challenges

    Enhancing the Vitality of theNational Institutes of Health:

    Organizational Change toMeet New Challenges

    Report by National Research Council and IoM

    Create a public process for considering proposed changes in the numberof NIH institutes or centers.

    Enhance and increase trans-NIH strategic planning and funding.

    Create a Directors Special Projects Program to support high risk, highpotential payoff research.

    Promote innovation and risk-taking in intramural research.

    2.

    4.

    7.

    8.

  • 8/8/2019 Volkow204

    8/50

    THE NIH ROADMAPTHE NIH ROADMAP

    An Agency-Wide Effort To Identify the

    Critical Roadblocks and Knowledge GapsThat Constrain Rapid Advancesin Biomedical Research Progress

    Molecular Libraries and Imaging Research Teams of the Future High-Risk Research

    Private-Public Partnerships Re-engineering the Clinical Research Enterprise

    Molecular Libraries and Imaging Research Teams of the Future High-Risk Research

    Private-Public Partnerships Re-engineering the Clinical Research Enterprise

  • 8/8/2019 Volkow204

    9/50

    What Has NIDA Done to Ensure Participationof Substance Abuse Researchers

    on the NIH Roadmap?

    What Has NIDA Done to Ensure Participationof Substance Abuse Researchers

    on the NIH Roadmap?

    Dr. Condon named NIDAs representative forthe Roadmap

    Program officers have contacted potential grantees toencourage them to submit grants for Roadmap RFAs

    Created a page on NIDA website that highlightsopportunities from the roadmap relevant to NIH

    grantees

    Periodic staff meetings with NIDA Director to reviewprogress and plan strategies

    Dr. Condon named NIDAs representative forthe Roadmap

    Program officers have contacted potential grantees toencourage them to submit grants for Roadmap RFAs

    Created a page on NIDA website that highlightsopportunities from the roadmap relevant to NIH

    grantees

    Periodic staff meetings with NIDA Director to reviewprogress and plan strategies

  • 8/8/2019 Volkow204

    10/50

    Ethics Issues at NIHEthics Issues at NIH

    New Initiatives to Strenthen the NIH Ethics Program:New Initiatives to Strenthen the NIH Ethics Program:

    Concern by congress that there may be conflict between the rol

    of NIH directors and of NIH scientists and private partnership

    Concern by congress that there may be conflict between the rol

    of NIH directors and of NIH scientists and private partnership

    Raynard S. Kington, M.D., Ph.D., NIH Deputy Director, appointedas Deputy Ethics Counselor (DEC) for the NIH and the Office of theDirector, NIH

    Blue Ribbon Panel established to review current NIH Ethics policies

    NIH Ethics Advisory Committee (NEAC) established(composed of members of the NIH community)

    Raynard S. Kington, M.D., Ph.D., NIH Deputy Director, appointedas Deputy Ethics Counselor (DEC) for the NIH and the Office of theDirector, NIH

    Blue Ribbon Panel established to review current NIH Ethics policies

    NIH Ethics Advisory Committee (NEAC) established(composed of members of the NIH community)

  • 8/8/2019 Volkow204

    11/50

    NIH Consolidation and Centralization Activities(occurring through several approaches)

    Outsourcing studies:

    NIH competes against outside contractorsExtramural Support was studied last year656 FTEs now in ICs (22 in NIDA) will be centralized into a new NIH Office theMEO Most Efficient Organization -- Implementation Date: April 1, 2004.

    Outsourcing studies:NIH competes against outside contractors

    Extramural Support was studied last year656 FTEs now in ICs (22 in NIDA) will be centralized into a new NIH Office theMEO Most Efficient Organization -- Implementation Date: April 1, 2004.

    NIH Administrative Restructuring Plan ARAC

    (Administrative Restructuring and Advisory Committee)Consolidation of functions in several areas including:Personnel, Grants Management, Budget, Acquisitions, Information Technology,Facilities, Financial Maagement and EEO

    NIH Administrative Restructuring Plan ARAC

    (Administrative Restructuring and Advisory Committee)Consolidation of functions in several areas including:Personnel, Grants Management, Budget, Acquisitions, Information Technology,Facilities, Financial Maagement and EEO

    Harmonization of and accountability for achieving both corporate NIH objectiveand IC-specific objectives Looking at Dual Reporting for senior IC staffHarmonization of and accountability for achieving both corporate NIH objectivesand IC-specific objectives Looking at Dual Reporting for senior IC staff

    FTE Ceiling imposed to limit the number of NIH employees at each institute;NIDAs is 373 in FY04FTE Ceiling imposed to limit the number of NIH employees at each institute;NIDAs is 373 in FY04

  • 8/8/2019 Volkow204

    12/50

    Budget UpdateBudget Update

  • 8/8/2019 Volkow204

    13/50

    NIDA BUDGETNIDA BUDGET(Thousands)(Thousands)

    Increase OverIncrease Over

    Prior YearPrior Year

    Increase OverIncrease Over

    Prior YearPrior Year

    AIDSAIDSAIDSAIDS

    TOTALTOTALTOTALTOTAL

    NonAIDSNonAIDSNonAIDSNonAIDS $659,431$659,431

    $301,514$301,514

    2003Actual2003

    Actual

    $960,945$960,945

    +8.2%+8.2%

    $677,808$677,808

    $312,979$312,979

    2004Estimate

    2004Estimate

    $990,787$990,787

    +3.0%+3.0%

    $703,328$703,328

    $315,732$315,732

    2005P.B.

    2005P.B.

    $1,019,060$1,019,060

    +2.9%+2.9%

  • 8/8/2019 Volkow204

    14/50

    Recent NIDA ActivitiesRecent NIDA Activities

  • 8/8/2019 Volkow204

    15/50

    Treatment Interventions Treatment Interventions

    Prevention Research (Children and Adolescents) Prevention Research (Children and Adolescents) Novel Approaches to Phenotyping Drug Abuse (RFA) Behavioral and Cognitive Processes in Adolescent Drug Abuse (RF Animal Models of Adolescent Drug Abuse (RFA) Prevention Research for the Transition to Adulthood (RFA)

    Consequences of Marijuana Use on the Developing Brain (RFA)

    Novel Approaches to Phenotyping Drug Abuse (RFA) Behavioral and Cognitive Processes in Adolescent Drug Abuse (RF Animal Models of Adolescent Drug Abuse (RFA) Prevention Research for the Transition to Adulthood (RFA)

    Consequences ofMarijuana Use on the Developing Brain (RFA)

    New NIDA PAs and RFAsNew NIDA PAs and RFAs

    Medications Development for Cannabis-Related Disorders (RFA) Medications Development for Cannabis-Related Disorders (RFA)

  • 8/8/2019 Volkow204

    16/50

    Training Training

    HIV/HCV HIV/HCV Drug Abuse Aspects of HIV/AIDS and Other Infections (PA) HIV/AIDS and Other Infections Among Drug Users in the Crimin

    Justice System (RFA) Targeted Integrative Research in Drug Abuse and HIV/AIDS in

    Pregnancy (RFA)

    Drug Abuse Aspects ofHIV/AIDS and Other Infections (PA) HIV/AIDS and Other Infections Among Drug Users in the Crimin

    Justice System (RFA) Targeted Integrative Research in Drug Abuse and HIV/AIDS in

    Pregnancy (RFA)

    New NIDA PAs and RFAsNew NIDA PAs and RFAs

    Research Education Grants in Drug Abuse and Addiction (PA) Research Education Grants in Drug Abuse and Addiction (PA)

  • 8/8/2019 Volkow204

    17/50

    PAs and RFA With Other NIH ComponentsPAs and RFA With Other NIH Components

    8 New PAs and4 New RFAs (Totaling $9.8 Million)

    8 New PAs and4 New RFAs (Totaling $9.8 Million)

    Focus predominantly on:

    CO-MORBIDITYMental illness

    Alcoholism

    HIV

    Focus predominantly on:

    CO-MORBIDITYMental illness

    Alcoholism

    HIV

  • 8/8/2019 Volkow204

    18/50

    NIDA/SAMHSAAddiction Technology Transfer Center (ATTC)

    Blending Initiative

    NIDA/SAMHSAAddiction Technology Transfer Center (ATTC)

    Blending Initiative

    Members of CSATs ATTC Network+

    NIDA Researchers

    Members of CSATs ATTC Network+

    NIDA Researchers

    BLENDING TEAMSBLENDING TEAMS

    Buprenorphine awarenesstraining and materials fornon-physicians in the drug

    abuse and addiction field

    Buprenorphine awarenesstraining and materials fornon-physicians in the drug

    abuse and addiction field

    Training materials andproducts to help programmanagers, administratorsand policy makers use

    Addiction Severity Index (ASI)results for management andprogram planning decisions

    Training materials andproducts to help programmanagers, administratorsand policy makers use

    Addiction Severity Index (ASI)results for management andprogram planning decisions

  • 8/8/2019 Volkow204

    19/50

    Highlights of Recent

    Meetings and Events

    Highlights of Recent

    Meetings and Events

    S i t f N i A l M tiS i t f N i A l M ti

  • 8/8/2019 Volkow204

    20/50

    Society for Neuroscience Annual MeetingSociety for Neuroscience Annual Meeting

    2002 ~ 471 of 13, 3932003 ~ 576 of 16,1552002 ~ 471 of 13, 3932003 ~ 576 of 16,155

    ~~~~

    Growth in Drug Abuse-Related PresentationsGrowth in Drug Abuse-Related Presentations

    NIDA-Sponsored Mini-ConventionNIDA-Sponsored Mini-Convention

    Opening Plenary Lecture

    THE ADDICTED HUMAN BRAIN

    Nora D. Volkow, M.D., Director, NIDA

    Opening Plenary Lecture

    THE ADDICTED HUMAN BRAIN

    Nora D. Volkow, M.D., Director, NIDA

  • 8/8/2019 Volkow204

    21/50

  • 8/8/2019 Volkow204

    22/50

    We Recently Released Our NewWebsite for Teens!

  • 8/8/2019 Volkow204

    23/50

    .. ....

    Educational Seminar for Primary Health Care ProvidersCo-sponsored by NIDA and the Sheppard Pratt Health SystemSheppard Pratt Conference CenterBaltimore MDDecember 17, 2003

    Tent at New Years Eve Spectacular(widely attended alcohol- drug- and smoke-free community event)Co-sponsored by NIDA in collaboration with the Maryland Chapter

    of the American Academy of Pediatrics, coalition partners andcorporate sponsorsBaltimore MDDecember 31, 2003

    Educational Seminar for Primary Health Care ProvidersCo-sponsored by NIDA and the Sheppard Pratt Health SystemSheppard Pratt Conference CenterBaltimore MDDecember 17, 2003

    Tent at New Years Eve Spectacular(widely attended alcohol- drug- and smoke-free community event)Co-sponsored by NIDA in collaboration with the Maryland Chapter

    of the American Academy of Pediatrics, coalition partners andcorporate sponsorsBaltimore MDDecember 31, 2003

    NIDAsPrimary Healthcare

    Outreach Initiative

    NIDAsPrimary Healthcare

    Outreach Initiative

  • 8/8/2019 Volkow204

    24/50

    Science HighlightsScience Highlights

    Percent of Students Reporting PastPercent of Students Reporting Past

  • 8/8/2019 Volkow204

    25/50

    Percent of Students Reporting PastMonth Use of Any Illicit Drug

    Percent of Students Reporting PastMonth Use of Any Illicit Drug

    19.419.4

    18.218.2

    17.317.3

    1616

    1717

    1818

    1919

    2020

    20012001 20022002 2003200311% Decline

    2001 to 2003

    11% Decline

    2001 to 2003Monitoring the Future Study 2003Monitoring the Future Study 2003

    GREAT NEWS!!

    Percent of Students Reporting Abuse ofPercent of Students Reporting Abuse of

  • 8/8/2019 Volkow204

    26/50

    Percent of Students Reporting Abuse of

    Pain Killers in Past 12 Months in 2003

    Percent of Students Reporting Abuse of

    Pain Killers in Past 12 Months in 2003

    1.71.72.82.8

    3.63.6

    7.27.2

    4.54.5

    10.510.5

    0.00.0

    2.02.0

    4.04.0

    6.06.0

    8.08.0

    10.010.0

    12.012.0

    OxycontinOxycontin VicodinVicodin

    8th Grade8th Grade

    10th Grade10th Grade

    12th Grade12th Grade

    Source: Monitoring the Future Study, 200Source: Monitoring the Future Study, 200

    Perce

    nt

    Perc e

    nt

    WORRISOME NEWS

    Numbers of New Abusers ofNumbers of New Abusers of

  • 8/8/2019 Volkow204

    27/50

    Numbers ofNewAbusers ofPrescription Drugs: 1965-2001

    Numbers ofNewAbusers ofPrescription Drugs: 1965-2001

    Source: SAMHSA, 2002 NSDUHSource: SAMHSA, 2002 NSDUH

  • 8/8/2019 Volkow204

    28/50

    Millions of Americans Abuse Prescription DrugsMillions of Americans Abuse Prescription Drugs

    SedativesSedativesStimulantsStimulants00

    0.50.5

    11

    1.51.522

    2.52.5

    33

    Millionsof

    Am

    ericans

    Millio

    nsof

    Americans

    3.53.5

    44

    4.54.5

    1.2 million1.2 million

    2.2 million2.2 million

    4.4 million4.4 million

    Use of Prescription Drugs for Non-Medical Purposes2002 National Survey on Drug Use and Health

    Use of Prescription Drugs for Non-Medical Purposes2002 National Survey on Drug Use and Health

    Pain RelieversPain Relievers

    Wh H h Ab f P i iWh H th Ab f P i ti

  • 8/8/2019 Volkow204

    29/50

    Why Has the Abuse of Prescription

    Drugs Increased?

    Why Has the Abuse of Prescription

    Drugs Increased?

    Increasing numbers of prescriptions(greater availability)

    Attention by the media and advertising(television and newspaper)

    Easier access(e.g. internet availability)

    Improper knowledge and monitoring

    (adverse effects go unrecognized)

    Increasing numbers of prescriptions(greater availability)

    Attention by the media and advertising(television and newspaper)

    Easier access(e.g. internet availability)

    Improper knowledge and monitoring

    (adverse effects go unrecognized)

    A P i ti I E RA P i ti I E R

  • 8/8/2019 Volkow204

    30/50

    As Prescriptions Increase Emergency RoomVisits For Non-Medical Abuse

    Have Also Increased

    As Prescriptions Increase Emergency RoomVisits For Non-Medical Abuse

    Have Also Increased

    Num

    berofPr e

    scriptions(in

    1000s )

    Numbe r

    ofPrescript i

    ons(in1000s )

    0

    10000

    20000

    30000

    4000050000

    60000

    70000

    80000

    1994

    1995

    1996

    1997 1

    998

    1999

    2000

    20010

    6000

    12000

    18000

    24000

    E D

    M e n

    tion

    s

    Source: SAMHSA, DAWN, 2002Source: SAMHSA, DAWN, 2002

    HydrocodoneHydrocodone

    OxycodoneOxycodone

    prescriptionsprescriptions

    prescriptionprescription

    emergencyemergency

    emergencyemergency

    I d M di Att tiIncreased Media Attention

  • 8/8/2019 Volkow204

    31/50

    Increased Media AttentionIncreased Media Attention

    Availability on the InternetAvailability on the Internet

    http://images.google.com/imgres?imgurl=www.menstuff.org/books/covers2/time.gif&imgrefurl=http://www.menstuff.org/issues/byissue/healthgeneral.html&hl=en&h=228&w=172&start=83&prev=/images%3Fq%3Dritalin%26start%3D80%26svnum%3D10%26hl%3Den%26lr%3D%26ie%3DUTF-8%26oe%3DUTF-8%26sa%3DN
  • 8/8/2019 Volkow204

    32/50

    Availability on the Internet

    Delivered in the Privacy of your Home

    Availability on the Internet

    Delivered in the Privacy of your Home

    Some reasons wyou should consid

    using thispharmacy

    Noprescriptionrequired!

    Some reasons wyou should consid

    using thispharmacy

    Noprescriptionrequired!

  • 8/8/2019 Volkow204

    33/50

    Other Reasons for ConcernOther Reasons for Concern

    These drugs can have serious medical consequences i.elethal overdose with pain killers, psychosis withstimulant medications

    Misuse in elderly populations who are particularlysensitive to adverse medical reactions

    Increase use by adolescents of drugs that may have longterm effects in brain development

    These drugs can have serious medical consequences i.elethal overdose with pain killers, psychosis withstimulant medications

    Misuse in elderly populations who are particularlysensitive to adverse medical reactions

    Increase use by adolescents of drugs that may have longterm effects in brain development

  • 8/8/2019 Volkow204

    34/50

    How Does NIDAs Science Help

    Fight Prescription Drug Abuse?

    How Does NIDAs Science Help

    Fight Prescription Drug Abuse?

    Continue Research on Prescription Drugs andContinue Research on Prescription Drugs and

  • 8/8/2019 Volkow204

    35/50

    p gon Treatment and Prevention

    p gon Treatment and Prevention

    When analgesics are injected

    they are much more addictive

    than when taken orally; hence

    formulations that can interferewith the drug effects if injected

    would decrease its diversion and

    abuse

    When analgesics are injected

    they are much more addictive

    than when taken orally; hence

    formulations that can interferewith the drug effects if injected

    would decrease its diversion and

    abuse

  • 8/8/2019 Volkow204

    36/50

    Development of Alternative Medications with noDevelopment of Alternative Medications with no

  • 8/8/2019 Volkow204

    37/50

    pDrug Abuse Potential

    pDrug Abuse Potential

  • 8/8/2019 Volkow204

    38/50

    FY 2005 and BeyondFY 2005 and Beyond

    NIDA FY 2005 InitiativesNIDA FY 2005 Initiatives

  • 8/8/2019 Volkow204

    39/50

    Treatment Interventions Treatment Interventions

    Prevention Research (Children and Adolescents)

    Prevention Research (Children and Adolescents)Gene/Environment Interactions

    Drug Exposure and the Developing Prenatal Brain

    The Effects of Drugs of Abuse Across the Lifespan Impact of Drugs, Risky Behavior and HIV on Adolescent Brain

    Drug Abuse Prevention and Treatment in Primary Care System Neurobiological Processes Underlying Co-morbidity

    Gene/Environment Interactions

    Drug Exposure and the Developing Prenatal Brain

    The Effects of Drugs of Abuse Across the Lifespan Impact of Drugs, Risky Behavior and HIV on Adolescent Brain

    Drug Abuse Prevention and Treatment in Primary Care System Neurobiological Processes Underlying Co-morbidity

    NIDA FY 2005 InitiativesNIDA FY 2005 Initiatives

    Pharmacogenetics and Medications Development Pharmacogenetics and Medications Development

    Using Science to Improve Providers Knowledge and Skills Using Science to Improve Providers Knowledge and Skills Training Training

    Systems and Translational ResearchSystems and Translational Research

  • 8/8/2019 Volkow204

    40/50

    genomegenomeprotein expressionprotein expression

    neuronal circuitsneuronal circuits

    DRUGS OF ABUSEDRUGS OF ABUSE

    socialsocial

    behaviorbehavior

    Systems and Translational ResearchApproaches in Addiction

    Syste s a d a s at o a esea cApproaches in Addiction

    Infrastructure Development and the Creation of Translational Research Centers Infrastructure Development and the Creation ofTranslational Research Centers

  • 8/8/2019 Volkow204

    41/50

    Brain, Behavior & Health RoadmapBrain, Behavior & Health Roadmap

    Brain, Behavior & Health InitiativeBrain, Behavior & Health Initiative

  • 8/8/2019 Volkow204

    42/50

    ,Mission

    To develop the knowledge and the technologynecessary for understanding how the human brain

    ,Mission

    To develop the knowledge and the technologynecessary for understanding how the human brain

    works and molds human behavior, how genes and environmental factors mold its

    development and function

    how it changes throughout the lifespan

    works and molds human behavior, how genes and environmental factors mold its

    development and function

    how it changes throughout the lifespan

    This knowledge will help to better understandbrain diseases including ADDICTION, and to

    develop strategies topromote optimal health

    This knowledge will help to better understandbrain diseases including ADDICTION, and to

    develop strategies topromote optimal health

    FIRST MILESTONEC i h illFIRST MILESTONEC t t i th t ill

  • 8/8/2019 Volkow204

    43/50

    Catalog ongoing projects that pertain

    to a brain/behavior/health initiative

    Identify scientific questions

    Identify research areas of redundancy and areas thatneed to be developed

    Identify technology or infrastructure that needs to be

    developed

    Optimize chances for integrating efforts across research

    centers, institutes and agencies.

    Catalog ongoing projects that pertain

    to a brain/behavior/health initiative

    Identify scientific questions

    Identify research areas ofredundancy and areas that

    need to be developed

    Identify technology or infrastructure that needs to be

    developed

    Optimize chances for integrating efforts across research

    centers, institutes and agencies.

    Create a matrix that willCreate a matrix that will

  • 8/8/2019 Volkow204

    44/50

    Matrix is based on a

    systems approach

    including

    data from all levels ofbiology: genes, proteins

    and their complexes,

    cell, circuits, behavior

    individual and social.

    The matrix includes

    projects in laboratory

    animals and implicitly

    addresses development

    and gender.

    Matrix is based on a

    systems approach

    including

    data from all levels ofbiology: genes, proteins

    and their complexes,

    cell, circuits, behavior

    individual and social.

    The matrix includes

    projects in laboratory

    animals and implicitly

    addresses development

    and gender.

    Social Network

    BRAIN BEHAVIOR & HEALTH ROAD MAP

  • 8/8/2019 Volkow204

    45/50

    2. Infrastructure& Projects

    2. Infrastructure& Projects

    3. Need forTechnology3. Need forTechnology

    1. ScientificQuestion

    1. ScientificQuestion

    GENEGENE

    PROTEINPROTEIN

    CELLCELL

    CIRCUITS/

    PATHWAYS

    CIRCUITS/

    PATHWAYS

    BEHAVIORBEHAVIOR

    SOCIAL

    NETWORKS

    SOCIAL

    NETWORKS

    PAs and RFA With Other NIH ComponentsPAs and RFA With Other NIH Components

  • 8/8/2019 Volkow204

    46/50

    p

    National Cooperative Drug Discovery Groups for the Treatment of

    Mood Disorders or Nicotine Addiction (NCDDG-MD/NA)Mechanisms of Alcoholic PancreatitisNeurotechnology Research, Development and EnhancementBioengineering Research PartnershipsHIV/AIDS, Severe Mental Illness and Homelessness (with NIAAA and NIMRuth L. Kirschstein National Research Service Awards for IndividualPredoctoral Fellows (F31)ELSI Regular Research Program (R01)ELSI Small Grant Research Program (R03)Transdisciplinary Tobacco Use Research Centers (with NCI and NIAAA)

    Group Therapy for Individuals in Drug Abuse or Alcoholism TreatmenScreening and Intervention for Youth in Primary Care SettingsHIV/AIDS, Drug Use and Highly Vulnerable Youth: Targeting ResearcGaps (with NIMH)

    National Cooperative Drug Discovery Groups for the Treatment of

    Mood Disorders or Nicotine Addiction (NCDDG-MD/NA)Mechanisms of Alcoholic PancreatitisNeurotechnology Research, Development and EnhancementBioengineering Research PartnershipsHIV/AIDS, Severe Mental Illness and Homelessness(with NIAAA and NIMRuth L. Kirschstein National Research Service Awards for IndividualPredoctoral Fellows (F31)

    ELSI Regular Research Program (R01)ELSI Small Grant Research Program (R03)Transdisciplinary Tobacco Use Research Centers(with NCI and NIAAA)

    Group Therapy for Individuals in Drug Abuse or Alcoholism TreatmenScreening and Intervention for Youth in Primary Care SettingsHIV/AIDS, Drug Use and Highly Vulnerable Youth: Targeting ResearcGaps (with NIMH)

    PAsPAs

    RFAsRFAs

    Monitoring the Future Study 2003P t f St d t R ti A Illi it D U

    Monitoring the Future Study 2003P t f St d t R ti A Illi it D U

  • 8/8/2019 Volkow204

    47/50

    Percent of Students ReportingAny Illicit Drug Usein Past Year, by Grade

    Percent of Students ReportingAny Illicit Drug Usein Past Year, by Grade

    8th Grade8th Grade

    10th Grad10th Grad

    12th Grad12th Grad

    00

    1010

    2020

    3030

    4040

    5050

    6060

    7575 7777 7979 8181 8383 8585 8787 8989 9191 9393 9595 9797 9999 0101 0303

    Recent NIDA Staff Appointments/ChangesRecent NIDA Staff Appointments/Changes

  • 8/8/2019 Volkow204

    48/50

    Steve Oversby, Psy.D. Medications Research Grants BranchJennifer Wong, Ph.D. Regulatory Affairs BranchSteve Oversby, Psy.D. Medications Research Grants BranchJennifer Wong, Ph.D. Regulatory Affairs Branch

    Susan Weiss, Ph.D. Chief, Science Policy BranchRobin Mackar, M.P.H. Deputy Chief, Science Policy BranchGayathri Jeyarasasingam Science Policy Branch

    Susan Weiss, Ph.D. Chief, Science Policy BranchRobin Mackar, M.P.H. Deputy Chief, Science Policy BranchGayathri Jeyarasasingam Science Policy Branch

    Division of Treatment Research & DevelopmentDivision of Treatment Research & Development

    Office of Science Policy and CommunicationOffice of Science Policy and Communication

    Arnold Mills -- Acting Chief, Epidemiology Research Branch

    Kevin Conway, Ph.D. Deputy Chief, Epidemiology Research BranchYonette Thomas, Ph.D. -- Deputy Chief, Epidemiology Research BranchJessica Campbell, Ph.D. Epidemiology Research BranchElizabeth Genexi, Ph.D. Prevention Research Branch

    Arnold Mills -- Acting Chief, Epidemiology Research Branch

    Kevin Conway, Ph.D. Deputy Chief, Epidemiology Research BranchYonette Thomas, Ph.D. -- Deputy Chief, Epidemiology Research BranchJessica Campbell, Ph.D. Epidemiology Research BranchElizabeth Genexi, Ph.D. Prevention Research Branch

    Division of Epidemiology, Services and Prevention ResearchDivision of Epidemiology, Services and Prevention Research

    Center on AIDS and Other Medical Consequences of Drug AbuseCenter on AIDS and Other Medical Consequences of Drug Abuse

    Center for the Clinical Trials NetworkCenter for the Clinical Trials NetworkTheresa Montini, Ph.D.Arnaldo R. Quinones, M.D.Theresa Montini, Ph.D.Arnaldo R. Quinones, M.D.

    Jag H. Khalsa, Ph.D. Acting Head, Medical Consequences UnitDenise BurnsJag H. Khalsa, Ph.D. Acting Head, Medical Consequences UnitDenise Burns

    Office of Extramural AffairsOffice of Extramural AffairsMark Green, Ph.D. Deputy DirectorMark Green, Ph.D. Deputy Director

    Office of the DirectorOffice of the DirectorCheryl Kassed, M.S.P.H., Ph.D., Special Assistant to the DirectorHelen Cesari, M.S., Special Assistant to the Deputy DirectorCheryl Kassed, M.S.P.H., Ph.D., Special Assistant to the DirectorHelen Cesari, M.S., Special Assistant to the Deputy Director

    NIHNIH

  • 8/8/2019 Volkow204

    49/50

    NIMHNIMH

    NCINCI

    NIAIDNIAIDNIAAANIAAA

    NINDSNINDS

    NICHDNICHD

    NIBIBNIBIB

    NIDCDNIDCD NHGRINHGRI

    NCMHDNCMHD

    FICFICNHLBINHLBI

    NIANIA

    NIAMSNIAMS NIDCRNIDCR

    NIDDKNIDDK

    NIEHSNIEHS

    NEINEI

    NIGMSNIGMS

    NINRNINR

    NCRRNCRR

    NCCAMNCCAM

    NLMNLM

    CITCIT CSRCSR CCCC

    NIDANIDA

    NIHNIH

  • 8/8/2019 Volkow204

    50/50

    NIDA-Sponsored Mini-ConventionNIDA-Sponsored Mini-Convention

    Cognition &Behavior:Functional Changes in Synaptic Transmission & Drug AbusCognition &Behavior:Functional Changes in Synaptic Transmission & Drug Abuse

    Dr. Susan Volman, DNBR, chairDr. Susan Volman, DNBR, chair

    Endocannabinoids in the Brain: From Micro to MacroDrs. Yu Lin and Nancy Pilotte, DNBR, co-chairs

    Mechanisms of Receptor & Transporter TraffickingDr. Christine Colvis, DNBR, chair

    Embryogenesis of Reward-Based BehaviorDr. Robert Riddle, DNBR, chair

    Young Investigators: Research & Funding Opportunities at NIDADrs. Susan Volman and Pushpa Thadani, DNBR, co-chairs

    Signal Transduction Mechanism in Drug Abuse & AddictionDr. David Shurtleff, DNBR, chair

    Neurobiological Mechanisms of Drug & Natural RewardDr. Paul Schnur, DNBR, chair

    Endocannabinoids in the Brain: From Micro to MacroDrs. Yu Lin and Nancy Pilotte, DNBR, co-chairs

    Mechanisms of Receptor & Transporter TraffickingDr. Christine Colvis, DNBR, chair

    Embryogenesis of Reward-Based BehaviorDr. Robert Riddle, DNBR, chair

    Young Investigators: Research & Funding Opportunities at NIDADrs. Susan Volman and Pushpa Thadani, DNBR, co-chairs

    Signal Transduction Mechanism in Drug Abuse & AddictionDr. David Shurtleff, DNBR, chair

    Neurobiological Mechanisms of Drug & Natural RewardDr. Paul Schnur, DNBR, chair

    Synaptic Transmission and Excitability: Genetically Encoded Biosensors forDefining Neuronal Circuits and Synaptic ChangeSynaptic Transmission and Excitability: Genetically Encoded Biosensors forDefining Neuronal Circuits and Synaptic Change

    Dr. Jonathan Pollock, DNBR, chairDr. Jonathan Pollock, DNBR, chair