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MYSOL381

A new additive makes the impossible possible,turning physically incompatible ingredients into thecomponents of a single, stable and homogeneous liquid.Easy to use, MYSOL 381 is the key to solubilizingfragrance oils, lipophilic vitamins and other apolar substancesin highly polar solvents, such as water and ethyl alcohol.

solubilizer No.1000381


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01. IDENTIFICATION OF THE PRODUCTTrade name: MYSOL 381ID code / catalog No. 1000381Short description: liquid solubilizer composed of nonionic surfactants and rheology modifying solventsINCI name: PEG-40 Hydrogenated Castor Oil; Trideceth-9; Propylene Glycol; Water (Aqua)

02. WORKING PRINCIPLES

Surfactants and surfactant systems can greatly increase the solubility of non-polar liquids in polar solvents, andvice versa. This phenomenon, which involves incorporation of the solute by aggregates of surfactant molecules, isknown as solubilization.Under suitable condition, liquid substances with high polarity differences can be turned into a single liquid phasethanks to surfactants and the intrinsic duality of their molecular characteristic. Surfactant molecules, which have apolar headgroup (hydrophilic group) and a nonpolar tail group (lipophilic group), arrange themselves around smallportions of solute, thus forming soluble microstructures, namely micelles where the group of the surfactant moleculethat is soluble in the solvent is facing outward (see the following illustration).

LIPOPHILIC/HYDROPHOBIC CHEMICAL MATRICE(essential oils, fragrance oils, other lipophilic substance)

POLAR/HYDROPHILIC CHEMICAL MATRICE(water/ethyl alcohol/water-alcohol mix)

HYDROPHILIC HEADGROUP

LIPOPHILIC TAIL

MYSOL 381 IS A COMPOUND SPECIALTY DESIGNED TO SOLUBILIZE HYDROPHOBICCHEMICAL MATRICES (ESSENTIAL OILS, FRAGRANCES AND OTHER LIPOPHILICCHEMICALS) IN WATER OR WATER-ALCOHOL SOLVENTS.

SMALL QUANTITIES OF MYSOL 381 FORCE THE CREATION OF A STABLEHOMOGENEOUS PHASE FROM TWO OR MORE LIQUIDS THAT OTHERWISE SEPARATE

INTO DIFFERENT PHASES DUE TO POLARITY DIFFERENCES.

SOLUBILIZATION OF IMMISCIBLE OR SLIGHTLY MISCIBLE LIQUIDS IS ACHIEVED THROUGHTHE FORMATION OF ORDERED AGGREGATES (MICELLES) OF SOLUBILIZER ANDNON-POLAR MOLECULES, WHICH ARE SOLUBLE IN THE INTENDED SOLVENTAND ARE SMALL ENOUGH (TYPICALLY 1 TO 3 nM) TO KEEP LIMPID THE SOLUTION.

MYSOL 381 EASY TO USE AND REQUIRES NO SPECIFIC MIXING TECHNOLOGY.

SURFACTANT SOLUBILIZER


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03. SOLUBILIZATION METHOD / PROCESSING NOTES

Gently mix the substance to be solubilized with the amount of solubilizer which is assumed as strictly necessaryto obtain the desired result. Once that is done, slowly add the solvent matrix (e.g. water, water-alcohol mix) withgentle mixing, avoiding trapping air in the mixture or fragmenting the substance to be solubilized (thereby formingan undesirable emulsion).The process can be generally facilitated by slightly warming the mixture. However, this option must be carefully

evaluated to ensure safety and to avoid undesirable chemical and chemical-physical transformations.In the event that a gel forms, attempt to repeat the process at a higher temperature, while maintaining safe workingconditions.If a cloudy mixture is produced, the entire process has to be repeated with a larger amount of solubilizer.

Note:Before beginning, make sure the individual ingredients are actually homogeneous.

04. SOLUTION TESTS

Test conditions:

4% solubilizer MYSOL 381Y% (values on the y-axis) quantity of solubilized essential oil/ fragrance oilqs to 100% distilled waterNTP (20C; 1 atm)

04.1 WATER SOLUTIONS

%ofs

olubilizedessentialoil/

frag

ranceoil

2%

3%

1,5%

2,5%2,5%2% 2%

4%

3%

5%

ORANGEBRA

ZILEO

WHITEMUSK97

PATCHOULYEO

SPICYF

IGS91

CITRONELLAJAWAEO

OZONICBLOSSOM26

LEMON

SAEO

GREENTEA53

SIBERIANPINEEO

GERANIUMEGYPTEO

ESSENTIAL OILS FRAGRANCE OILS


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05. GENERAL DISCLAIMER

The information contained herein represents the extent of Moellhausens understanding of the art and must not inany way be considered an intimation or warranty of the fitness of the product for any particular purpose.The product referred to herein is sold on the basis of its compliance with the respective specifications (materialtechnical data sheet), and the manufacturer makes no warranties, express or implied, as to the fitness of theproduct for any particular purpose and on the condition that the purchaser/user performs the necessary controlsand tests to verify the fitness of the product for the intended use.Moellhausen shall not be liable for any irresponsible, improper or illegal use, direct or indirect, of the information or ofthe product represented herein, and it shall not be liable for any damage arising from any use in connection therewith.

Test conditions:5% essential oil/ fragrance oilY% (values on the y-axis) quantity of solubilizer MYSOL 381qs to 100% water-alcohol solvent 60/40 wt/wt (60% distilled water + 40% ethyl alcohol)NTP (20C; 1 atm)

04.2 WATER-ALCOHOL SOLUTIONS

DocumentM321

-Copyright2012,

byMoellhausenS.p.A.-

Allrightsreserved.

%ofsolubilizerMYSOL3

81 13%

5%

4% 4%

12%

6% 6%

4% 4%

2%

ORANGEBRAZILEO

WHITEMUSK97

PATCHOULYEO

SPICYFIGS91

CITRONELLAJAWAEO

OZONICBLOSSOM26

LEM

ONSAEO

GREENTEA53

SIBERIANPINEEO

GERANIUM

EGYPTEO

ESSENTIAL OILS FRAGRANCE OILS


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DocumentM321

-Copyright2012,

byMoellhausenS.p.A.-

Allrightsreserved.

STRONG POINTS

GREATLY INCREASES THE SOLUBILITY OFHYDROPHOBIC SUBSTANCESIN WATER AND WATER-ALCOHOL SOLVENTS

SUITABLE FOR BOTH ACIDIC AND ALKALINEMATRICES (pH 3 -11)

LOW QUANTITIES REQUIRED

GOOD RESISTANCE TO FOAM FORMATION

RELATIVELY LOW VISCOSITY

VERSATILE / MODERATE MATRIX DEPENDENCY

HLB (HYDROPHILIC-LIPOPHILIC BALANCE) VALUE: ~ 15

EASY USE AND HANDLING


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Moellhausen S.p.A. - Head Office

Via Torri Bianche, 9

20871 Vimercate (MB), ItalyTel.+ 39 039.685.6262Fax+ 39 039.685.6263E-mail [email protected] www.moellhausen.com

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